Before the departure of the old factory director, Fang Hanmin proposed the short, medium and long-term scientific and technological development plan of the Red Star Pharmaceutical Factory, which is a concrete embodiment.

At that time, all the veterans of the factory, including the chief engineer Lao Xia, either thought that Fang Hanmin's plan was ambitious and unrealistic, and could not be turned into reality at all, or they thought that he was grandstanding and deliberately pleasing the leaders.

In the face of a voice of doubt, the old leader Director Yuan seemed very calm, he did not rush to express his position, but asked Fang Hanmin a question, "In the short, medium and long-term scientific and technological development plan, why should we first imitate the drugs whose patents of foreign pharmaceutical companies have expired?" ”

Fang Hanmin thought for a while, "Let me make an analogy, the development and growth of an enterprise is like the growth of a baby, you must first learn to crawl, then learn to walk, and then learn to run." Imitation of drugs with expired patents of foreign companies is the process of babies practicing crawling, and the creation of new drugs in the future belongs to the normal walking or running stage, how can a person learn to walk or run before learning to crawl? ”

The old factory director nodded in agreement, "Well, that's the truth!" However, by imitating drugs whose patents have expired, can new drugs be created? ”

"That's not necessarily, but through the imitation process can cultivate a group of high-quality scientific and technological talents, which is the basis of innovation, only with a talent base, can we talk about innovation. However, just like a person's growth, learning to crawl in infancy can only mean that his body control and limb coordination have been exercised, laying the foundation for walking and running in the future. ”

"Well said! I hope that your scientific and technological development plan can bring a bright future to Red Star Pharmaceutical Factory! The old factory director not only fully agreed with Fang Hanmin's short, medium and long-term plan, but also strongly recommended Fang Hanmin to the higher authorities to replace him before leaving office.

Despite this, Fang Hanmin is too young after all, he has no foundation in the Red Star Pharmaceutical Factory, and he is often criticized for his shortcomings in terms of academic qualifications, he is very aware of his situation, except for the deputy director Wang in the leadership team who blatantly opposes him, the other veterans are the same as the chief engineer Lao Xia, who obeys his leadership on the surface, but in fact has resistance.

Just before Fang Hanmin proposed the first step to implement the specific scientific and technological development plan, that is, to prepare for the implementation of the imitation test of the drug with the expiration of the patent, at a symposium of scientific and technological personnel of the whole factory, Su Wenquan, the deputy chief of the technical department who had a holiday with Fang Hanmin, mocked Fang Hanmin in person, "Director Fang, since you want to realize your plan, why not directly develop new drugs, what kind of ability is it to engage in imitation!" Aren't you afraid of being laughed at? ”

Although the other party had bad intentions, Fang Hanmin disagreed, "Section Chief Su, you are an old engineer, you must have received systematic professional training during college, you should know that the development of new drugs is innovation, and innovation is not building a castle in the air!" ”

"Needless to say, it's hard to say innovation directly! Now that you know the difficulty of innovation, aren't the plans you put forward bluffing for yourself? ”

Lao Su's cynicism and unrelenting pushed Fang Hanmin into a corner, "Section Chief Su, if you don't understand the laws of scientific research, please don't jump to conclusions!" Don't you think it's a fantasy for a baby who hasn't learned to walk yet, but wants to walk or run like an adult? All innovations in the field of scientific research are built on a strong foundation of research and development, and the imitation of drugs with expired patents is not only to consolidate the foundation of technology research and development, but also to prepare for the product upgrading of Red Star Pharmaceutical Factory. Without imitation, how can we talk about innovation? This basic logical relationship, as an old engineer, have you never heard of it? ”

These remarks not only pointed out the ignorance of Lao Su, but also made the reason very clear; a group of old scientific and technological personnel, including Su Wenquan, no longer raised objections, but their attitude was still not positive, but many young scientific and technological personnel were extremely interested in implementing the scientific and technological development plan, and raised many questions of concern at the forum, and Fang Hanmin gave detailed answers.

After analyzing the situation that happened at that symposium, Fang Hanmin had a plan in his heart, and he decided to completely rely on the young scientific and technological personnel in the factory in the process of implementing the scientific and technological development plan.

Although the basic knowledge of young scientific and technological personnel may not be much better than that of the previous generation, they at least have a positive attitude, flexible mind, and consciousness to keep up with the pace of the times, plus they are in the prime of life, full of energy, these factors are conducive to the normal development of imitation experiments.

Because the old comrades don't care about this matter, from the beginning of the trial to the present, Fang Hanmin has not mentioned the progress of the trial of generic drug development in various meetings, and now has achieved phased results, when it is necessary to invest more resources to promote the overall advancement, he convened a special meeting attended by the heads of relevant departments, hoping that everyone will work together to promote this generic product to the pharmaceutical market as soon as possible.

Chief engineer Lao Xia is about to retire in less than two years, and when this drug completes technical development, is successfully registered and introduced to the market, he may have left the unit and gone home to recuperate, he does not want to help the filing and registration of generic drugs, Fang Hanmin thinks it is excusable.

But the negative attitude of Lao Xue, director of the General Engineering Office, made Fang Hanmin feel a little ignorant of current affairs, these old Xue has nothing to do in the position of director of the General Engineering Office, it can be said that he is completely chaotic, and he also enjoys the treatment of the deputy factory, Fang Hanmin turned a blind eye to this, after all, Lao Xue has left the technical post for many years, and it is really difficult for him to be responsible for a specific technical work.

Fang Hanmin asked Lao Xue to be in charge of this work, the original intention was to give him a chance to participate, because he was three or four years younger than Mr. Xia, and he could not retire within three or five years.

Fang Hanmin believes that if under the leadership of Lao Xue, this generic drug is filed with the regulatory department and completes the registration license, which can be regarded as his contribution to the generic drug project.

Maybe he didn't understand Fang Hanmin's kindness, or he didn't want to get involved with Fang Hanmin's project like Mr. Xia's thoughts, Lao Xue's negative attitude made Fang Hanmin lose patience with him, and in the end, this work was led by Wan Cheng, the young technical section chief, and the director of the chief engineering office, Lao Xue became a dispensable supporting role. ......

After the meeting, Wan Cheng, the chief of the technical section, personally went to the provincial regulatory department to get back the drug filing application materials, and then compared them one by one according to the requirements of the materials.

It took more than two months for the preparation of the reporting materials, and two staff members of Wancheng and the technical department came to the provincial pharmaceutical supervision department with materials filled with three file bags, classified the materials, and submitted them to the relevant departments of the Provincial Pharmaceutical Administration. They lingered in the provincial capital for two more days and did a few official things, and just as they were about to return to their units, the hotel communication room notified Wan Cheng to answer the phone.

Wan Cheng hurriedly ran to the communication room, and when he picked up the phone, he knew that it was the attendance officer of the technical department of the unit calling, "Section chief, are you still in the provincial capital?" Director Lin of the Registration and Regulation Department of the Provincial Medical Administration just called and asked you to go to his place, saying that he had something to do with you. ”

Hearing this news, Wan Cheng was very happy, he thought that the filing procedures had been completed, and sincerely admired the efficiency of the regulatory department.

Wan Cheng did not dare to delay, explained the situation to the two colleagues, asked them to wait at the hotel, got on the bus by himself, and arrived at Director Lin's office an hour later.

Lao Lin is a middle-aged man with a polite manner, with a pair of myopic glasses on the bridge of his nose, and when he saw Wan Cheng enter the house, he got up to greet him, "Comrade Xiao Wan, you are the technical section chief of Hongxing Pharmaceutical Factory, right?" It seems that I should call you Section Chief Vanke. ”

"Director Lin is polite, I'm young, it's more casual to call Xiao Wan, I don't know what Director Lin is looking for me?"

Lao Lin pointed to the chair opposite and motioned for Wan Cheng to sit down, "Regarding this generic drug you declared, I have some information that I need to know from you. ”

Across the desk, Wan Cheng sat down opposite Director Lin, "Oh, aren't our filing and declaration materials not fully prepared?" ”

"That's not it, the materials you prepared according to the regulatory requirements are fully in line with the regulations, but I want to know some situations outside the regulatory requirements, I wonder if the chief of Vanke can provide them?"

"What happens outside of regulatory requirements? What does Commissioner Lin want to know? ”

Director Lin, who graduated from a top university in China in the mid-60s with a major in organic synthesis, was engaged in related research in a research institute of the Chinese Academy of Sciences until the mid-80s, and had a deep accomplishment in the field of pharmaceutical synthesis. Because in the past few years, there have been several drug fraud incidents in the province, which have caused a very bad impact on the society, in order to strengthen the supervision of the industry, the organization department has transferred several skilled technical elites from the relevant institutions in the province to enrich the Provincial Pharmaceutical Administration, and Lao Lin is one of them.

After seeing the registration materials submitted by Red Star Pharmaceutical Factory, Lao Lin first felt very pleased, he did not expect that domestic companies could imitate patented drugs with excellent efficacy in such a short period of time.

After spending a whole day of working hours, after reviewing the filing materials of the Red Star Pharmaceutical Factory from beginning to end, there was no fault with the materials themselves, but as the director of the registration and regulation department of the regulatory department, Lao Lin's attitude was quite cautious, because he had a general understanding of the process technology of this drug, and he thought that it would not be easy for a local state-owned pharmaceutical company with a small reputation, even if it was placed in a professional pharmaceutical research institute, to successfully imitate this drug.

Thinking of the counterfeit drug incident a few years ago, Director Lin was more careful, he felt that it was necessary to interview the people of the Red Star Pharmaceutical Factory in person to see if he could find any problems from it, so he grabbed the phone in front of him and dialed a long-distance number, and connected to the technical department of the Red Star Pharmaceutical Factory.

"Can you contact him, while he is still in the provincial capital, let him come to me, there are some things that need to be discussed with him."

At that time, the means of communication were backward, and in order to facilitate contact, after Wan Cheng and others arrived in the provincial capital, they called the technical department and informed them of the name and telephone number of the hotel they were staying in.