August 26, morning.

After Zhang Chen sent his parents and grandfather to the company, he once again learned about the progress of the experimental animals with Wang Lele.

The mouse model built for Beihe Biologics has passed the gestation period and will be weaned and live independently in a few days, and is expected to be delivered on August 31.

The requirements of many customers are not complicated, and even most of them just ask to be humanized mice.

It's just that the first batch of breeding humanized mice, just after the gestation period, is estimated to be around the 31st, and can be delivered to all customers.

The first batch needs to be bred, and there will be no need to wait so long in the future, as long as it is in stock, it can be delivered directly.

The mouse model that Zhang Chen exchanged in the system was originally a mouse model with a whole gene humanization.

Delivering such mice to the customer is completely beyond their requirements.

It is used for new drugs or some vaccine animal experiments, and the effect is much better than that of ordinary mice.

Moreover, the growth rate of mice exchanged from the system is three times that of ordinary mice.

However, Zhang Chen did not make a specific distinction, and all humanized mouse models have a unified price.

If it is the same as Beihe gene, it is required to do fixed-point gene knockout or knock-in on the basis of humanized mice, then the fee will be a little more expensive.

However, the experimental animals of Chenyue Biology are completely worth the money, not only the animal models have quality assurance, but also the growth rate is very fast, which is equivalent to speeding up the research and development progress.

Wang Lele manages all the projects in an orderly manner and without any chaos.

However, now there is only one company called Beihe Biotech, which needs to be specially transformed.

At present, the workload of mouse reproduction management is not large, and it is only necessary to ensure that mice always have sufficient inventory.

In the future, if other animals are added, or if other companies do special modifications, the management difficulty will increase exponentially.

And Wang Lele is also responsible for sequencing services, and when the time comes, the experimental animals can only be exchanged for a [primary gene cloning housekeeper] to manage.

Zhang Chen found out, and in the end, each product needs a managed clone to be in charge.

Not only in terms of management, but also in terms of the core secrets of the product, the more high-tech the product, the more the core things can not be leaked out.

Zhang Chen has always been very cautious in this regard, at least until now, there have been no problems.

Of course, it's all about the system, and without managed clones, a lot of secrets may not be kept.

If you keep the secret and Zhang Chen does everything himself, then the company's development speed will not be so fast, don't even think about earning 600 points a day now.

After Zhang Chen carefully explained to Wang Lele again, he took Zhang Yue to the People's Hospital together.

As of now, all of Mona's physical indicators are normal.

It can be concluded that the gene therapy drug will not cause any effect on healthy subjects.

Jiang Zhenguo had taken this medicine a long time ago, and there had been no abnormal situation until now.

But according to the requirements, the clinical trial still has to be carried out, and it is not just the time of the day.

In the days to come, Mona would come to the hospital from time to time for a comprehensive check-up.

Close monitoring of this day can only show that so far the drug has no effect on healthy people.

It stands to reason that there will be drug residues in the body when general drugs are ingested, but it is only a matter of how much, especially such gene therapy drugs.

Small kiosk app

People don't know enough about this drug, and sometimes when they hear the word gene, they become extremely cautious.

will consider whether this gene introduced into the body will follow people for a lifetime and whether it will cause potential unknown effects on the body.

There are also those genetically modified crops, which people avoid even more.

But even without a system, Zhang Chen can say with certainty that gene therapy is theoretically safe.

The gene introduced into the human body is not integrated into the chromosome, it is only free in the cell, regulating the translation of proteins, so there is no need to consider that this gene will cause other adverse effects.

The safety of genetic drugs is mainly related to the delivery system.

The therapeutic gene is just a nucleic acid sequence, and without the appropriate means, there is no way to send it to the designated location of the human body.

Now, the most commonly used method is to use the virus as a vector to deliver therapeutic genes to the designated location in the human body.

Viruses are specific, some viruses only infect eye cells, while others only infect liver cells.

This specificity of the virus is used to deliver therapeutic genes.

Genetic engineering technology is then used to modify the virus in all aspects, so that it becomes non-pathogenic, but still retains its specificity.

Many companies often have problems with this design, resulting in the pathogenicity of the virus still existing, or the specific modification is not in place, and the therapeutic gene cannot reach the designated position, which will produce unexpected toxic side effects.

And the gene therapy drug produced by the system has almost achieved perfection in the modification of the virus.

The therapeutic gene can be delivered to the designated location very precisely, and the virus is not pathogenic in the slightest.

Zhang Chen and Zhao Yingbo discussed the next test arrangement.

With the addition of yesterday's old man, there will be five volunteers at the same time today.

All five subjects have the same characteristic, and their families are not wealthy enough.

They don't have extra money to spend on cardiovascular disease, and they're all elderly.

At their own insistence, the elders persuaded their sons and daughters to agree to participate in the trial of this gene therapy drug.

Every family has its own difficult scriptures, and every family has its own difficulties.

The long-term high cost of chemical drug treatment has made the already not wealthy family even more stretched.

In order not to drag down their children, they chose such a way, and after doing the test experiment, they still have 500,000 cash to take.

This is also a point that they value very much.

Of course, Zhang Chen's original intention was not to use the 500,000 to tempt people to do this test experiment.

He just felt that as long as someone trusted him unconditionally and gave 500,000 in return, it should be.

Except for the old man yesterday, the other four all suffered from high blood pressure all year round, which eventually led to various physical diseases.

The treatment of various chemical drugs can only relieve the symptoms, but cannot completely eradicate them.

Now I finally came across a drug that can effectively cure cardiovascular diseases, and I am really unwilling not to try it.

Although it is only the clinical trial stage, after checking the relevant information, the family also has a certain understanding of drug clinical trials.

Clinical trials are subject to the approval of relevant national departments, and it is not possible to achieve this level of any drug.

In addition, this time not only can 500,000 cash be taken, but if there are some unexpected situations with this drug, the state will also compensate accordingly.

Since the state has made a commitment in this regard, it means that there is probably not much of a problem with it.

So they all took the attitude of giving it a try and participated in this volunteer call.