Huang Ruifang felt a little incredible.

Obviously, there is no condition for intravenous administration, why does Zhang Chen still use this method of administration.

Zhang Chen smiled slightly, he actually didn't know much, but fortunately, during the simulation, the system gave detailed supplementary information.

I didn't think it was anything to look at, so I didn't copy it to them.

But now that Huang Ruifang asked, Zhang Chen immediately realized that this seemed to be the advantage of these two products.

"I've done some modifications to add a mutant protein to the adenovirus capsid so that it eliminates the tropism of the natural virus and ensures a tumor-targeted treatment outcome.

In addition, this modification also unexpectedly enhances the specificity of oncolytic adenovirus, which can ensure zero damage to normal ordinary cells.

Finally, this modification can also allow oncolytic adenovirus to infect nerve cells or mesenchymal stem cells, use the cells as transport carriers, and finally accurately deliver to the location where tumor lesions occur, that is, this modification enhances the mobility of oncolytic adenovirus. ”

Now Zhang Chen's memory has reached a very terrifying level, and after reading the information a little, he can almost write it down.

Although I haven't understood it yet, I can still do it by filling it in a cup and reading it out to shock the two people present.

Although my memory has improved a lot, it is still very difficult to learn the system materials.

Just like the information of oncolytic adenovirus, for Zhang Chen, he just remembered, but did not fully understand and digest.

"The Sword Comes"

However, the standard of the system to reward points must be fully understood, and even to the point that it can be used in reality.

If you really memorize all the contents, you can get points, then the systematically published "Molecular Biology" should have been changed a long time ago.

When I first took the intermediate "Thinking Capsules", the memory in that state could completely memorize the content of this "Molecular Biology" within an hour.

But until now, there is still the last section of the most difficult knowledge node, which is worth at least 6000 points.

Zhang Chen estimated that it would take at least a month to completely win the last knowledge node.

After Huang Ruifang and Liu Qiang listened to Zhang Chen's words, they were all shocked.

So, what kind of transformation have you always made, what kind of fairy protein has been added, and it has brought such a miraculous effect.

"Therefore, it is because of this transformation that we can have the following data."

Liu Qiang looked a little faster, and he had already seen the data listed behind.

The shock in her heart was no less than when she confessed to Huang Ruifang at the beginning, and she agreed without hesitation.

The oncolytic virus therapy takes effect for at least one day or more.

You're good, in less than half an hour, no matter how big the tumor is, it can be killed directly.

The gene therapy drug for cardiovascular treatment can also have a perfect effect in half an hour.

Why, your medicine can't escape this half-hour cycle, right?

Liu Qiang complained frantically in his heart, but on the surface, he still tried his best to remain calm.

Looking at Liu Qiang, whose face was flushed, Zhang Chen wanted to laugh a little, what is the matter with you, just say it, how uncomfortable it is to hold back.

He continued to fill the cup and said abruptly: "By the way, the onset time of the drug is also due to the addition of this mutant protein." ”

Liu Qiang didn't say it, he forgot about this stubble.

"If you look at the information later, the gene sequence that regulates this protein has been listed in the data."

Although this is the core of these two products, Zhang Chen did not intend to hide it from them.

This is a R&D personnel, and they all have to sign a confidentiality agreement and a competition agreement.

If these key things are kept from them, then how do they do relevant research?

Moreover, if they can really make some optimizations, it will save a lot of points.

It's unlikely, but that doesn't mean it doesn't work.

Huang Ruifang and Liu Qiang are rare talents in the field of oncolytic viruses.

Otherwise, the boss of Beihe Gene would not have pulled them over to bring the project as soon as they graduated.

Those who can start a company are not fools, although they still failed to succeed in clinical practice in the end, but they are only the last step away.

Drug development is very difficult, and it is not something that can be done.

Huang Ruifang and Liu Qiang, it is already very good to be able to make products like that.

If it weren't for the two of them insisting on leaving, the boss of Beihe Gene would definitely not let them go easily.

"I see the characteristics of these two products, there are far more than these, in order to achieve such a good therapeutic effect, its oncolytic effect must be very powerful, but to enhance the oncolytic effect alone, it is actually very simple, the difficult thing is that after enhancement, it will not affect normal cells."

At this time, Huang Ruifang discovered a new problem.

Zhang Chen raised his eyebrows, followed his memory, and explained the two of them again.

"Well, you're right, this needs to be grasped well, but I found a suitable therapeutic gene, which can enhance virus-induced apoptosis, so that the adenovirus death protein can be expressed in an appropriate amount, so that it can be both safe and effective, and the design of this gene expression box is also available in the attachment at the back."

After listening to Zhang Chen's words, Huang Ruifang and Liu Qiang glanced at each other speechlessly.

Therefore, the reason why these two products are so exaggerated is because of the addition of a protein and a gene.

Well, or rather, two genes were added.

In fact, the translation of proteins is regulated by genes.

That's a small change, big wisdom, right?

Liu Qiang swallowed his saliva involuntarily and said: "Mr. Zhang, then let's start the verification experiment as soon as possible, I don't think there is anything else that needs to be improved, and the company's production equipment is also complete, if the verification meets expectations, then it can be directly pilot-produced, on experimental animals, and in vivo verification." ”

Zhang Chen nodded, "However, you can also try it, make some transformation on this basis, try to make these two medicines more perfect, and don't worry about these few days." ”

"Okay."

"In addition, if your project team needs to recruit people, you can go and ask Mr. Zhang, she will cooperate with you, you can recruit in advance, and the configuration must be complete."

Zhang Chen plans to assign a special person to be responsible for each project.

From early R&D to process development to series production, he intends to have all the people involved.

There will be more and more projects in the future, and it is necessary to manage the project separately from now on.

Otherwise, when the time comes, it will only become more and more chaotic.

Thinking of this, I can't help but feel a little worried, and the current workstation seems a little nervous.

Fortunately, the construction progress next door has not fallen behind.

On the contrary, under Zhang Chen's money offensive, coupled with perverted materials, the construction progress was much faster than expected.

Construction of the research base has also begun.

Zhang Chen is looking forward to the day when the entire park is built.