574 Fecal Capsules (I)

The patient was stunned by Director Zou's words, and looked at the short and drooling Director Zou in a daze.

Is he serious?

Fecal capsules? Name implies...... If you understand correctly, you have to eat yourself?!

Is he really not joking?

……

In the review room.

The guests and the bald host were also taken aback by Director Zou's words.

The bald host tilted his mouth and looked at Professor Shen.

Shen ...... Mr. Shen. The bald host was obviously stimulated, and he stammered, "Fecal capsule, is it homophonic, I heard it wrong?" It should be the resolution resolution. ”

"No, poop means poop." Professor Shen said lightly.

“……”

“……”

“……”

The atmosphere in the review room was a little weird and awkward.

Professor Shen knew that this was not just a layman, even if some large tertiary hospitals ranked outside the top 20 in the country had not carried it out, so he began to explain.

"Clostridium difficile is an obligate anaerobic bacterium of the genus Clostridium, which is very sensitive to oxygen and difficult to isolate and culture, so the first researchers gave it a simple and crude name - Clostridium difficile.

Clostridium difficile was first discovered in 1935, and it was discovered in 1977 that it was associated with pseudomembranous enteritis caused by long-term clinical use of certain antibiotics, and it has only been noted since then. ”

"The production of Clostridium difficile is related to the long-term use of large amounts of antibiotics."

"Teacher Shen, is that what everyone said about the abuse of antibiotics in hospitals?" One of the guests asked.

The bald host glared at him unhappily and gave enough hints.

If you really can't speak, how can you scold a bald head in front of a monk?

"Misuse of antibiotics." Professor Shen didn't care very much, he smiled slightly, "The most abused antibiotics are animal husbandry, but public opinion ...... Hahaha, don't talk about this, we now have to approve clinical pharmacy for the use of antibiotics in clinical practice, which is very troublesome. ”

"Teacher Shen, you continue to talk about fecal capsules." The bald host pulled the topic back and continued to control the scene.

"Clostridium difficile is present in the gut of about 50 percent of infants at 12 months of age, and about 3 percent of children over two years of age, but Clostridium difficile occurs less frequently in healthy adults."

"Because this patient has been using antibiotics for a long time, Clostridium difficile appeared in the intestine, and the diagnosis speed of the First Affiliated Hospital is very fast, which is quite good." Professor Shen praised, "This is the diagnosis, let's talk about the fecal capsule." ”

Fecal transplantation, also known as fecal transplantation, is the transplantation of functional flora in the feces of healthy people into the gastrointestinal tract of patients, rebuilding the intestinal flora with normal function, and realizing the treatment of intestinal and extraintestinal diseases.

Other names are "intestinal bacteria transplantation" or "intestinal microbiome transplantation". ”

"......" The bald host was slightly stunned.

His expression was difficult, and his face was full of simple and rough difficult clostridium.

"Teacher Shen, do you mean to eat other people's stool?" One of the guests asked.

"That's about what it means." Professor Shen smiled, "Actually, the main ingredients of many drugs cannot be detailed. For example, luminous sand, for example...... cough cough, such as the new rehabilitation liquid commonly used in clinical practice. ”

"I know this, American cockroach." The bald host tried his best to soothe the atmosphere in the review room, "During the epidemic a few years ago, many people had the reaction of swallowing razor blades, and drinking rehabilitation new liquid worked very well. But I have a few friends who say it's cockroach juice and don't drink it when they die. ”

"Hahaha." Professor Shen smiled, "Fecal capsules are another matter. Thousands of patients worldwide have been treated with fecal transplants, and the United States is the most rapidly growing in this area, with some institutions establishing blood bank-like stool banks to serve as a support platform for this treatment. ”

"Manure Depot ......"

"Manure Depot ......"

Professor Shen's words were amazing, and the bald host and guests were speechless. The bald host, who is experienced and has a strong ability to save the scene, doesn't know how to continue.

In fact, he does not reject the topic of, pee and fart, after all, eating, drinking, lazing and sleeping is a major event in life. But the word fecal bank was beyond the cognition of the bald host, and he didn't know what to say at all.

"The results of a new study, published in the Journal of the American Medical Association, show that frozen excreta is encapsulated in capsules for the treatment of Clostridium difficile infection.

The 1.6-gram synthetic pill will be as safe and effective as traditional excrement transplantation techniques. Within 8 weeks, 18 out of 20 patients had complete relief of diarrhea after taking 30 or 60 stool pills. ”

"Of course, I know it's disgusting."

Professor Shen glanced at the host and the guests present, smiled slightly, and explained.

"It sounds disgusting, but it makes sense that human feces are the excrement of the human body, and the main components are bacteria.

Current research has proved that the function of intestinal bacteria is very important, and some scholars even believe that the intestinal flora is an important organ of the human body, so logically speaking, transplanting the stool of a normal healthy person to a patient is very similar to the concept of organ transplantation. ”

"The intestinal flora belongs to the organs?" Mao Mao whispered.

"Figuratively, figuratively, certainly not a real organ." Professor Shen said, "But the production and clinical application of fecal capsules have been carried out in China. Although there is no fecal bank, as far as I know, the First Affiliated Hospital of Hangzhou Medical University should be able to make fresh frozen fecal capsules. ”

“……”

Fresh......

Frozen ......

For the first time, the guests associated these two words with feces, and for a while, they couldn't accept it at all.

"Antibiotics cause a disturbance of the intestinal flora, and the intestinal flora needs to be rebuilt, to put it mildly - eating is the best way to do it. In nature, the intestinal bacteria of many young herbivores are constructed from the excreta of practical mothers. ”

……

……

In the private room of the barbecue, Director Liu sighed.

"Lao Bai, when will our hospital have similar equipment?"

"It's impossible, it needs a low temperature of more than 100 degrees below zero, and it's not something that can be eaten with a piece of." Director Bai obviously understood this, and he said with a little unhappiness.

"Have you applied?" Director Liu knew Director Bai too well, and when he saw that he was unhappy, he guessed why.

"I asked the gastroenterology department to mention it, but because the equipment was too expensive, I didn't approve it." Director Bai said.

"Something is good, will it be expensive?" Director Liu asked a strange question.

"If our hospital is just entered, it should be very expensive, but if it is launched, it will be much cheaper. For example, the United States is $40 a piece of. ”

"It's disgusting, you can't be more elegant." Director Liu frowned.

"You're a urologist, a sewer, tell me about gentleness?"

"We're going to be part of the sewer, and you're talking about gastrointestinal surgery and anorectal surgery."

(End of chapter)