Chapter 167: Artemisinin, Artemisia annua!
The clinical manifestations are so complex, latent and intermittent, cold and hot.
With the level of medical technology in ancient times, it is natural that there is almost no way to deal with this disease.
Don't look at the Baicaotang Divine Doctor of Da Zhou, his brows are twisted together.
Even the era in which Xiang Yan was originally staying.
It was not until 30 June 2021 that WHO declared Huaxia malaria-free.
From this, we can see what level this disease is, and what is the difficulty of the Great Zhou era.
But fortunately, Xiang Yan is not from this era, and she happens to have a certain understanding of this disease.
In this case, there is no way to do it if it is not true.
Xiang Yan just smiled, so that Xiang Yuxia didn't have to worry.
Xiang Yuxia was suddenly very surprised:
"What? Yan'er, do you have a way or a recipe for this malaria? ”
"You read it in the old book you were talking about, too?"
Xiang Yan explained the principle of malaria infection and the clinical manifestations.
Xiang Yuxia was suddenly shocked:
"What's the name of that book? Lend me a look! ”
"Yan'er, this is a major event related to the progress of all mankind, you can't hide your secrets."
Xiang Yan pretended to be distressed:
"I don't remember when I read that ancient book, and I don't remember where it is now, and I can't find it if you ask me to look for it now."
"But I still remember some of the treatments mentioned in the book!"
First, basic treatment.
First, bed rest should be given during the attack and 24 hours after the fever has subsided.
Secondly, it is necessary to pay attention to the supply of water, give liquid or semi-liquid diet to those with poor appetite, and give a high-protein diet during the recovery period; Those who vomit and diarrhea and cannot eat should be properly rehydrated; People with anemia may be given iron supplements.
In this era, there is no oral liquid for iron, so you can only replace it with foods with high iron content.
Then, take care to keep warm during chills; Heavy sweating should be dried with a dry towel or a warm wet towel in time, and the sweaty clothes and quilts should be changed at any time to avoid cold.
Physical cooling is used in case of high fever, and patients with excessive fever can be cooled by drugs because of unbearable high fever.
Patients with dangerous fever should closely observe their condition, find changes in vital signs in time, record the amount of entry and exit in detail, and do a good job in basic nursing.
The second aspect is drug treatment.
And this drug is famous.
Artemisinin!
Artemisinin is a colorless needle-like crystal, with a melting point of 156~157 °C, soluble in chloroform, acetone, ethyl acetate and benzene, soluble in ethanol and ether, slightly soluble in cold petroleum ether, and almost insoluble in water.
Because of its special peroxide group, it is thermally unstable and susceptible to decomposition by moisture, heat and reducing substances.
Artemisinin is the most effective drug in the treatment of malaria drug resistance, and artemisinin-based combination therapy is also the most effective and important means for the treatment of malaria.
The extraction process is very complicated, and Xiang Yan did not introduce it in detail.
Rather, it directly points out the plant species needed to extract artemisinin.
Artemisia annua.
But even with this plant, it is impossible to extract artemisinin with the current level of science and technology.
It can only be said that there are some ways to take advantage of the useful elements in it.
Although there is no guarantee of a 100% cure, at least it is more or less effective.
The immediate priority is to grow this plant on a large scale in vegetable greenhouses.
"If the plant you are talking about can really be useful in the treatment of malaria, the economic benefits will be incalculable!"
Xiang Yuxia said,
"Malaria is prevalent all year round in the south, while in the north it is endemic between spring and autumn."
"The medicine you grow is the best cure."
"But even if it can't be cured."
Xiang Yuxia paused here before continuing.
"Even if it can't be cured, the money you can make from this medicine every year can reach the level of millions of silver!"
Hearing Xiang Yuxia's estimate, Xiang Yan was also very excited.
"In that case, let's not hurry up!"
"Auntie, don't say that my little stone has a good thing and doesn't want you, how can you say, do you want to participate in the planting and development of this medicine?"
Xiang Yuxia thought about the potential huge value behind this matter.
Thinking about it again, Xiang Yan had already proved in Jiangnan that the knowledge in that ancient book was indeed useful.
The profits are great, and the odds of success are not small.
Whoever doesn't do this is a fool.
So Xiang Yuxia gritted her teeth.
"Yan'er, I believe you, you go to the account room in the hall to withdraw money! How much do you want! ”
"Great!" Xiang Yan said excitedly.
……
Although he had only been out for a while, Xiang Yan had a large amount of money in his hands.
But now he was frowning.
It's just that the problem of the greenhouse has encountered difficulties.
The greenhouse at home has its fixed purpose, and there is no land to grow Artemisia annua.
Even if you can make a little effort to make a little effort, it will be a drop in the bucket and will not solve the problem at all.
Looking at their busy vegetable greenhouse, people and tenants are going in and out of it.
Xiang Yan was also stunned like Xiang Yuxia.
"Stinky boy, what's wrong?"
Xiang Guozhong saw it, so he came over and asked.
"I want to grow something new."
Xiang Yan replied,
"But there isn't enough land at home."
"Dad, do you think I'm lifting a stone to shoot myself in the foot."
"When I wanted to use the land, the law prohibiting the sale of land that I had promoted blocked my way."
"At this time, I can't help but wonder if it would be a bad idea to ban the sale of land."
Xiang Guozhong smiled.
"That's it?"
"Little stone, your brain is usually very bright, why can't you turn a corner sometimes?"
Xiang Yan asked:
"How?"
Xiang Guozhong replied:
"You don't have to be your own land to use it."
"Just let the owner of the land grow what you want."
Xiang Yan shook his head:
"I've thought about it, but if I think about it, I can't do it."
"It's not safe, don't say it."
"And I have too much land to use, too many owners, do I want to talk about them one by one?"
"When the time comes, there will be a little problem, and I will have to notify and coordinate, dozens or hundreds of households, so I won't do anything else?"
"Every day, I spend all my time just talking."
"And the land owned by each family is too small, if I don't connect all the land, how can I build my greenhouse?"
Xiang Guozhong suddenly laughed again:
"That's why you can't turn your brain when you get there."
"If you're afraid of being unsafe, it's good to find someone you can trust."
"Since there are many owners, it's good to find only one person."
"Since the land is too small, then it is good to find someone who owns a lot of land!"
Xiang Yan suddenly said unexpectedly:
"After the promotion of the law prohibiting the sale of my land, there are still such people?"
Xiang Guozhong said a name, and Xiang Yan suddenly understood:
"Isn't that your daughter-in-law who hasn't been through the door?"
"Princess Yuanhua!"