After reaching the Sacred Seal level, simply cutting off the opponent's head or penetrating the organ can no longer cause fatal damage.

Usually, only by completely annihilating the opponent's soul can it be regarded as truly killing a Saint Seal-level life.

Including the higher level of the stage, at least according to the information left by the original wizard civilization, unless the other party is the world master who has completely mastered the origin of a world, otherwise the soul annihilation will be on the Holy Seal or even the next two levels

Chapter 16 of "The Wizard's Path": Realm and Domination System is in the middle of the fight, please wait a moment,

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