From Qi Lele's reaction to seeing Wang Sanma, Xie Zi'an guessed that what she was going to say was related to smallpox, so he interrupted all the way and took her home, lest she speak amazingly.

However, he still underestimated his little wife after all.

Rao was mentally prepared, but he was still shocked by her words.

"Smallpox, can it be prevented?"

Qi Lele nodded: "Yes!"

Xie Zi'an's hand behind his back pinched his palm hard, trying to ease his demeanor and keep his voice steady: "I have never heard of this matter, and I would like to hear about it."

"As far as I know, there are probably two ways. But the principle is the same, they all implant smallpox-related viruses in people who have never had smallpox."

As soon as these words came out, Xie Zi'an was silent for a long time, he looked at Qi Lele quietly, if it wasn't for her who said this, he was afraid that he would immediately blast people out.

It's just gibberish!

Qi Lele actually knew how shocking her words were, if it weren't for the person in front of her, she probably wouldn't be so straightforward.

After a long time, Xie Zi'an said, "But I am wrong? You mean, to actively transmit smallpox to people?"

"Yes!" "Because smallpox can be immunized once and not a second time," he explained.

"Then we can artificially implant a small amount of smallpox virus into the body to make people mildly infected, so that by the time the disease strikes, the symptoms are very mild, and they can heal on their own with almost no treatment, and there will be no scarring."

"Because of the nature of the smallpox virus, even a very mild infection, once cured, the body can produce an immune effect, so as to achieve the purpose of preventing smallpox."

Tse thought for a longer time this time: "Smallpox is a virus? If this virus enters the body, it will only kill if it is in large quantities, and it will not kill and infect others if it is in small amounts."

Qi Lele said, "That's probably the case. If the infection is mild, it is still contagious, but it is not serious, and as long as you pay more attention, it will probably be fine."

Xie Zi'an asked, "Then how can we ensure that only a small amount of virus enters the body?"

"Take off the scabs of people who have had smallpox, grind them into fine powder, mix them with clean water, spread the clean cotton into thin sheets, wrap the mixed pox seedlings with cotton, form them into jujube pits, tie them with thread and stuff them into their nostrils, and take them out after six hours.

After Xie Zi'an groaned, he shook his head: "It's too risky to act like this. Even if the dosage is small, there will always be seriously ill people, and if you don't check it, it will be a big disaster. Wouldn't that be a calamity without a cause?"

Qi Lele said: "There are no absolutes in the world, not to mention the prevention of smallpox, even if it is a small illness and pain in daily life, there will also be accidents."

The room fell silent again, Xie Zi'an frowned, the smallpox was so terrifying, he really didn't dare to touch it easily.

"Allow me to think again."

"Actually." Qi Lele looked at Xie Zi'an and said slowly, "If you think this method is too risky, there is another way, and the risk is much lower."

Xie Zi'an raised his eyebrows: "Is there another way?"

"Yes, cowpox!"

"Cowpox? Could it be that cows also have smallpox?"

"Clever!" "Cowpox is a smallpox virus in cattle, which is also a virulent infectious disease in cattle, and can also infect us, but people will only have mild symptoms after infection, and generally do not have much physical discomfort," said Qi Lelele.

"Since the vaccinia virus and the smallpox virus are essentially the same antigenic nature, people can also be immune to smallpox after being vaccinated with cowpox."

Xie Zi'an was silent for longer this time.

Qi Lele knew that he needed time to digest, so he quietly accompanied him on the side.

Unlike antibiotics, smallpox prevention is a passive defense skill, and once proven effective, any person in a position of authority will only want to do it as soon as possible rather than keep it secret.

Even if it finally reached the ears of the emperor, it would only reward the proposer and continue to promote it vigorously.

That's why Qi Lele dared to bring it up without hesitation.

"Madame first talked about human pox, and then came to mention cowpox, compared to the two, if I wasn't stupid, I would choose cowpox."

Xie Zi'an thought thoughtfully: "So, the smallpox prevention method that Madame wants to talk about is actually a kind of cowpox?"

Qi Lele generously admitted: "If I had started with cowpox and got the smallpox virus from cattle into people's bodies, you might not accept it, would you?"

Xie Zi'an was noncommittal, and only asked, "Have you ever planted cowpox?"

Qi Lele shook his head, "The place I went to, smallpox has been completely eradicated."

Xie Zi was relieved: "Smallpox can be completely eliminated?"

"Yes, as long as everyone is immune to smallpox, there will be no room for the smallpox virus to survive, and it will naturally disappear."

"So, as long as everyone is planted with cowpox, can they be wiped out?"

"Yes, it's just that it may take a long time, and it may take several generations of continuous cowpox to make it disappear completely."

"Actually, in the earliest days, we used the method of planting human pox, and only later did we find a safer cowpox, and after the widespread practice of cowpox, the smallpox virus slowly disappeared or even disappeared," said Qi Lelele.

Xie Zi'an finally made up his mind, and said, "In this case, let's give it a try."

Qi Lele didn't know what this decision meant, nor did he know what kind of entanglement Xie Zi'an had experienced in his heart, the courage to break through the cauldron, and the unparalleled absolute trust in her.

But she also has something she wants to do for Xie Zi'an: "Since I proposed it, and only I know how to operate it, then I'll try it first."

"No!"

Qi Lele was not surprised, and said in a resolute tone: "It must be me, otherwise I won't tell you what to do!"

"Since cowpox comes from human pox, there must be something in common between the two, if you don't say it, I can infer one or two."

Qi Lele stretched out his index finger and shook it: "That's not necessarily! Why is cowpox safer than human pox? In addition to the relatively small physical reaction caused by cowpox, there is also the difference between the extraction of pox and the way of planting pox!"

Xie Zi'an stopped talking.

Qi Lele also looked at him silently.

This method was proposed by her, and the deliberate planting of the smallpox virus into the human body is simply unbelievable and even appalling in the eyes of people in this world.

If Xie Zi'an is asked to find someone else to try, no matter how loyal those people are to Xie Zi'an, it is difficult to guarantee that they will not be resentful, after all, smallpox is too terrible!

Only when she tried it herself, could the others be convinced, and then sincerely accept the matter of cowpox.

How could Xie Zi'an not know what she was thinking?

Because he knew, he wouldn't agree even more.

In his eyes, there is nothing in this world that is worth the adventure of the people in front of him!