Chapter 105: Targets (Additions)
After Li Qingye arranged these things.
looked at another piece of information that Chen Jianxiong had just reported, which was about Huaguo's side.
After reading the relevant information, Li Qingye immediately ordered: "Fili, strengthen the investigation of various control areas, especially foreign personnel." ”
"Yes, boss."
Chen Jianxiong was also a little worried: "Boss, I suspect that the world has been ....... ”
Li Qingye is more sure of this than him: "Don't doubt it, it's like finding a cockroach in the house, and it must be everywhere secretly." ”
"Shall we be more vigilant, then?" Chen Jianxiong became more and more worried.
Li Qingye thought for a while, nodded and said, "It's okay, take this opportunity to let Luzon and Honsawady close the country for a while." ”
"I see." Chen Jianxiong also knows that this is one of the few things they can do now.
As for other things, even the Homo sapiens company, which has increased its power a lot, does not have the ability to meddle in the family affairs of the five hooligans.
Suddenly, Li Qingye ordered again: "During the investigation, you will send some of the target's blood samples over as soon as possible, I need to study it and prepare just in case." ”
"Yes, I'll arrange it right away." Chen Jianxiong is convinced of Li Qingye's scientific research ability in the field of biology, as long as Li Qingye is willing to make a move, Homo sapiens will not at least be powerless.
Looking at Chen Jianxiong, who was leaving in a hurry, Li Qingye sat on the sofa and fell into deep thought.
This sudden situation affected many of his plans.
Originally, he wanted to take action against Du Jianxin's family in the near future, but now due to the grounding of planes and the increase in the investigation of entry, the soldiers who are preparing to carry out the task will not be able to pass for a while.
Li Qingye was not annoyed by this, after all, it was impossible for everything to be smooth sailing.
And it's not that he doesn't have a backup plan, but he needs a few months to adjust.
Pulling his thoughts back to reality, Li Qingye washed his face in the bathroom, then passed through the disinfection area, and then passed through layers of tight gates, and came to his exclusive laboratory.
The AIDS target drugs he developed for Domino and others have entered the final testing stage.
More than a dozen scumbags infected with AIDS were held in special wards by soldiers' assistants, monitoring the condition of these test subjects at all times.
"How's it going?"
Assistant No. 15 reported to him: "The subject's body is not abnormal, and the HIV in the body is basically undetectable, but it cannot be ruled out that it is an illusion." ”
HIV is very cunning, often evading the eradication of drugs, then lurking, waiting until the effects of the drugs have passed, and then continuing to come out and make waves.
The target drug developed by Li Qingye is different from the traditional AIDS treatment drug, nor is it the RNA technology that has just emerged in recent years.
This is a customized drug that specifically targets a specific gene, somewhat similar to an advanced version of an RNA vaccine.
The core of its technology is to quickly determine the genetic sequence of the virus, and then use genetic recombination technology to create a suicide virus specifically for the virus, and then inject the suicide virus into the patient's body, so that the suicide virus and the virus in the patient's body will die together.
In fact, this thing is one of the derivative technologies of the genetic bomb.
Therefore, this target drug does not allow the patient to produce antibodies, but it can kill the virus, and it is a special specific drug.
Since it is a drug that is specific to a specific virus, it is necessary to carefully analyze the genes of the virus in the patient's body before it can be manufactured.
In other words, there is no way that the targeted drug will work on all AIDS, it can only kill specific HIV.
For example, the 15 experimental subjects in front of them, the HIV in their bodies is called AIDS, but the genes of these AIDS are different, and they must be customized for each person.
If the traditional technology is followed, the production cost of this exclusive target drug is definitely a sky-high price.
Fortunately, Homo sapiens' technology is different from traditional genetic technology.
The technical points of manufacturing exclusive target drugs are as follows:
First, genetic testing technology, in this regard, Homo sapiens currently has biochips and DNA storage, which applies gene spot determination technology that can be quickly detected, and results can be obtained almost in seconds.
Second, genetic recombination technology, Li Qingye designed a general virus bomb framework - [TYBD—(X)—JYZD].
This framework is very simple, and the general framework consists of six parts: immune deception gene sequence, structurally stable gene sequence, target chimeric gene sequence, blasting gene sequence, autologous replication restriction gene sequence, and timed disintegration gene sequence.
Among them, the target chimeric gene sequence is the position used to quickly insert the gene of the virus target.
Although at the stage of target gene insertion, only a small percentage of the target gene will be successfully inserted into the framework at a time.
But as long as one of them is successful, the successful part can be extracted through rapid genetic testing, and then autologous replication can be turned on using hormones and viral culture media until enough target drugs are obtained.
This session usually only takes about 5~12 hours.
In fact, the simplified version of this technology is the current RNA vaccine technology.
The advantage of the target drug is that the speed of killing the virus is very fast, the degree of killing is almost 100%, and the virus does not have time to mutate at all, and it will not make the virus resistant to drugs, and there are almost no side effects on the patient's body.
The disadvantage is also very obvious, the patient's body cannot produce antibodies, there is a risk of secondary infection, and it cannot be used in areas without relevant supporting facilities.
This targeted drug is more suitable for viruses such as AIDS, Ebola, and rabies, but not for viruses such as smallpox and influenza.
The reason why smallpox and influenza are not suitable is not that they cannot be used, but that these viruses have the characteristics of aerosol transmission, and the virus is killed in the patient's body, but there may be other sources of infection in the surrounding environment, which can easily cause repeated infection.
In the event of repeated infection, the virus gene should be re-tested and the target drug should be manufactured according to the viral gene sequence.
Although Homo sapiens' genetic testing technology is very fast and very cheap, about a few cents at a time; The cost of cultivating the raw materials of target drugs is also only a dozen yuan.
The problem is that such repeated tossing and turning can easily cause leaks, and it also requires a lot of manpower, especially valuable professional medical manpower.
Therefore, Li Qingye will use two other schemes for aerosol-borne viruses such as smallpox.
One is a simplified version of the target drug technology - RNA vaccines.
The other is bacteriocins (i.e., antibiotics) that target universal targets.
In fact, these two technologies are not bad, at least the technology in Li Qingye's hand is more perfect than the current RNA vaccine technology and antibiotic technology of the same type in human beings.
The principle of the two is basically the same, but Li Qingye has upgraded and improved.
For example, RNA vaccine technology, the full name of the technology in Li Qingye's hand is: complex-multi-target combined RNA vaccine technology.
Specifically, more than 10 gene targets are determined for the circulating virus strains, and then several 10-target RNA vaccines are developed, and then these vaccines are combined and used together.
In the face of this vaccine, even an RNA virus with a very fast mutation rate is invincible with two fists.
The same is true for targeted antibiotics.
This is also the drug that Li Qingye intends to launch on the market through the Aoba Group and Homo Sapiens.
As for the exclusive target drug, this technology can only be used on a small scale internally, after all, it involves gene bomb technology.
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