Chapter 134: Observation Period
In the end, this artificial intelligence heart transplant operation took six and a half hours of operation time.
When they saw the stable operation of the artificial intelligence heart, the smooth continuation of the patient's vital characteristics, and the various work indicators meeting psychological expectations, the two brothers showed a gratifying smile on their faces.
One aspect that needs to be paid close attention to over the next month is the change in the patient's body temperature, an increase in which there is inflammation, and a decrease in the temperature that may lead to the non-continuation of life.
As for rejection, it is basically non-existent.
The biggest feature of the AI heart is that it does not need to be matched with the patient's heart. Because there is no blood type, there is no such thing as a match.
This is the same as the bypass devices that are implanted in various parts of the heart. Have you ever heard of a case of rejection of implanted body organs?
At present, the success rate of human heart transplantation is 95% for the entire medical community, the survival rate for 1 year after heart transplantation is 85%-90%, and the mortality rate is about 4% for each year thereafter.
Rejection occurs in at least one episode in 50% to 80% of patients, and most have no obvious manifestations, but left ventricular dysfunction or atrial arrhythmias occur in 5% of patients.
The peak of rejection after heart transplantation is about 1 month, and it gradually decreases over the next 5 months, and begins to stabilize in about 1 year.
One year after heart transplantation, most patients achieve class I cardiac function, and more than 70% of patients can return to full-time work.
Patients who survive more than 1 year after heart transplantation have a good state of functional recovery, but their exercise levels are still lower than normal, and there is a possibility that their heart function will gradually improve over time and sympathetic function recovers.
Heart transplantation is usually used for patients with end-stage heart failure, coronary heart disease, arrhythmias, hypertrophic cardiomyopathy, congenital heart disease, etc., which are at risk of death and cannot be controlled with medications.
For predictors of 1-year mortality, pre-transplant includes preoperative ventilatory dysfunction or left ventricular assister, cachexia, female recipient or provider, other diagnoses other than heart failure or coronary artery disease, and post-transplant including elevated reactive protein and troponin levels.
The most common cause of death within 1 year is acute rejection or infection, and the main cause of death after 1 year is coronary vascular disease or lymphocyte proliferation after heart transplantation.
In view of this, the barriers to the completion of human heart transplantation in the early stage are rejection and infection, and the later obstacles are coronary vascular disease and lymphocyte proliferation.
However, these problems can only occur with matched heart transplants. And the AI heart avoids just that.
Therefore, the only thing to pay attention to at present in this operation is the problem of infection, and the most obvious reaction of infection is the change in body temperature.
Ou Zhou and Jiang Yang, the brothers, took this as the first key point for monitoring, and in other aspects, they were monitored by vital signs instruments.
As for the ECG, it is only useful when doing blood circulation outside the body, and it is useless in front of the artificial intelligence heart.
The operating status of the AI heart will be monitored by vital signs instruments during hospitalization and detected by a smart control meter worn on the wrist after discharge.
The work was given to the three cardiac surgeons who participated in the operation as the first priority, and the monitoring was the first priority.
Ou Zhou and Jiang Yang only have a routine check-up once a day.
Obviously, as long as the body temperature is normal and the vital signs instrument does not alarm, then everything is OK.
On this day, Ou Zhou, Jiang Yang, and Ke Feier discussed the commissioned manufacturing of the artificial intelligence heart with Jin Cheng and Liao Yunhui, the two helmsmen in the conference hall.
"Mr. Ou, we have contacted all the medical device manufacturing companies on the island, and they seem to have questions about the production prospects of artificial intelligence hearts, and even directly express their disbelief, how to deal with this matter?"
"If it really doesn't work, just look for it overseas, and if it doesn't work, we will acquire a company on Bay Island, and we will manage the processing and production of artificial intelligence hearts by ourselves." Ou Zhou said.
Jiang Yang continued: "I prefer to acquire nearby on the island, so that it is easy to manage, and on the premise of not delaying the production of artificial intelligence heart, it can also develop the production of other product businesses." ”
Koffiel agreed to the proposal: "Rather than being controlled by others, take the initiative." ”
Ou Zhou looked at the two helmsmen and asked, "Which topic do you two prefer?" ”
The two helmsmen said almost in unison: "It is ideal to buy nearby." ”
"Okay, since everyone has agreed to make a nearby acquisition, let's go with this plan. In addition, I also have an idea that the target of the acquisition should preferably involve the production of cardiovascular and cerebrovascular drugs, so as to facilitate the development of the second phase of drugs that are matched with artificial intelligence heart in the future. Ou Zhou said again.
"There are three companies on the island that have cardiovascular and cerebrovascular medicine research and medical device production at the same time, namely Jiahe Medical, Guirong Medical and Ginseng Sputum Biotechnology." Jin Cheng said like a treasure.
Ou Zhou nodded and said with a smile: "Among the three companies, which one do you tend to acquire?" ”
"Jiahe Medical." Jin Cheng's words are concise and to the point.
"Tell me your reasoning?"
"Compared with the other two companies, Jiahe Medical has its own three fist products, namely epinephrine preparations, ginseng injections, and cardiac defibrillators. And the size of the company is also relatively moderate. ”
"Is Jiahe Medical a public company?" Ou Zhou asked with interest.
"It's a public company."
Ou Zhoudao instructed: "Let's take a look at this company on the computer!" ”
Jin Cheng opened the Bay Island stock market on the computer and retrieved Jiahe Medical Company.
Ou Zhou saw that Jiahe Medical has a total share capital of 170 million, fully circulating, and the stock price is NT$23.
The main business is the development and production of cardiovascular and cerebrovascular medicines, and the development and production of medical devices.
Listing date, September 1999.
He focused on the shareholding of the three major shareholders: the first largest shareholder holds 23 percent of the shares, the second largest shareholder holds 12 percent, and the third largest shareholder holds 10 percent. The remainder are outstanding shares.
Ou Zhou paid attention to it in his heart, and said with a smile: "Two helmsmen, do you have any securities accounts?" ”
Jin Cheng and Liao Yunhui glanced at each other and said in unison, "Yes." ”
"That's easy to do," Ou Zhou slapped his fist and said with a smile, "Hmph, if you don't do the business that comes to your door, you have to force us to use some means." He looked at Jin Cheng and Liao Yunhui, "You open several securities accounts separately, and inject no less than NT$500 million into each account." Then create some bad news for Jiahe Medical Company, make its stock price plummet, and you will secretly eat it in a big way. Fifty-five percent of the shares outstanding in the market are 98 million shares. If we buy more than 25 percent of the total share capital, we will exceed the 23 percent of the largest shareholder, and we can control it. ”
Jin Cheng and Liao Yunhui said happily: "I didn't expect Mr. Ou to know so much about the capital market at such a young age. It's really impressive. ”
"Haha, these are all plots, I'm just using them to practice. Who told them to toast and not eat, and to eat and punish wine? Ou Zhou smiled.
"However, there is a problem with this, this matter can only be carried out secretly, once it is detected by the major shareholders, they will unite with the other two shareholders to release good news to hedge the stock price, and may even compete with us for chips, resulting in a sharp rise in the stock price. If this happens, it is likely to disrupt our acquisition plans. ”
"Two helmsmen, we have two purposes for taking this move. First, smoothly control Jiahe Medical Company. Second, in case the major shareholders perceive that there is a situation like the one you mentioned, but as long as we hold the full stake in the company, we have the bargaining chips to negotiate terms with them. At that time, they can agree, and if they don't, we will continue to create some episodes for him. Hehe, let him put out the fire today, fill the pit tomorrow, and be busy. ”
Jin Cheng and Liao Yunhui laughed and said: "Mr. Ou, your style of play is a bit of a scoundrel, but it is very practical, so let's do it." ”
"The capital market was originally a battlefield without gunpowder. In order to benefit the common people, it is necessary to use some extraordinary means. Ou Zhou smiled.
Jiang Yang gave Jin Cheng a bank card and said with a smile: "There are 2.1 billion Hong Kong dollars in it, you exchange it for 10 billion New Taiwan dollars, and start our acquisition action plan." ”
Jin Cheng took the bank card and said with a smile: "Rich is the uncle, since Jiahe Medical is in our favor, it is the dish on our plate." ”
After the two helmsmen left, Ke Feier said with a smile: "There is really a father and a son, Ou Dad has been in the securities market for many years, and he has never played such a trick. ”
"Sister, the so-called big things are not informal, and we are forced to do this. Who made them ignorant? ”
Jiang Yang smiled: "Yes, we can be regarded as salute first and then soldier." If they happily agree to the production of the artificial intelligence heart, why should we play this play? ”
"People say that the rivers and lakes are sinister, but in my opinion, where there are interests, there are sinister." Koffiel laughed.
"Sister, we are not doing this for ourselves, so it is not insidious and cunning. If you look at it from another angle, over time, after Jiahe Medical grows in our hands, the shareholders will make a lot of money, but I am afraid that it will be too late to thank us! ”
"If you look at it this way, we're forcing them to make money, not taking their assets." Jiang Yang said with a smile.
"So, as far as this matter is concerned, we should be at ease, not ashamed." Ou Zhou Road.
Ke Fei'er nodded: "If you understand it like this, isn't it a good thing?" ”
"Now that the three of us have agreed on the same opinion, let's go and see the first artificial intelligence heart transplant patient who has contributed to the great cause of mankind, right?" Ou Zhou suggested.
The three of them then walked out of the hall and went to the monitoring room of the Artificial Intelligence Heart Research Institute.
The doctor on duty saw them come in and got up to report on the patient's performance.
The patient is not yet awake but is breathing steadily.
Ou Zhou personally took the patient's temperature and observed the vital signs. Indicators show that everything is off to a good start.
Jiang Yang also repeated those actions.
Ou Zhou looked at the doctor on duty and said: "What this patient carries is not only our years of hard work, but also the gospel of all mankind, from the moment he received an artificial intelligence heart transplant, all his reactions and performances will be recorded in the history of human history!" ”
The doctor is from the Cardiovascular and Cerebrovascular Department of the Affiliated Hospital of Wandao University, and is a well-known expert on the island, named Zeng Yiming, who is just over forty years old, nodded and said: "I understand what Mr. Ou means, I will do my best to do every record and patient monitoring work." ”
Ou Zhou nodded: "Let's join hands and work together to complete this great cause of human beings to eliminate evil and promote good!" ”
"Let us join hands to accomplish the great cause of eliminating evil and promoting good."
This sentence has become the lifelong goal of the Institute of Artificial Intelligence Heart Transplantation.