Chapter 306 Preparation of Nano Reagents
Four o'clock in the afternoon.
Zhao Heng came to the No. 1 laboratory of the School of Life Sciences of Yenching University.
In the office, Professor Li Hongwei was in a very good mood when he saw Zhao Heng coming.
"Come, Xiao Zhao, drink tea."
Li Hongwei personally poured a cup of tea for Zhao Heng and put it on the coffee table in front of him.
"Professor, how's the experiment going?"
Zhao Heng nodded, picked up the teacup and took a sip, and asked Li Hongwei.
"With your joining, the experiment has gone a lot smoother recently, Xiao Zhao, this is an important role you play."
Li Hongwei said with great appreciation.
What he regretted recently was that Zhao Heng couldn't join his laboratory full-time, so that the progress of many of his experiments could be greatly improved.
An assistant like Zhao Heng can be said to be something that every scientist can meet but cannot find, and it is not something that can be found casually.
The most important thing is that if you have the ability and quality of Zhao Heng and your knowledge, under normal circumstances, you will not be an assistant to others.
"Professor, I'm here this time because I want to ask you for help."
Zhao Heng nodded and continued.
He knows what kind of person Li Hongwei is, and there is no need to say those polite words, the time of top scientists is very precious, and they generally don't waste their time on those useless politeness.
In fact, people like Li Hongwei have a lot of appetite for Zhao Heng, compared to the people in the hospital, such as Gao Jun and Dean Liu Shangming, after they took the position, intentionally or unintentionally, they had some more polite parts.
Like Professor Li Hongwei, although he leads a top laboratory, he is more like a scientist than a leader.
"Well, you say."
Li Hongwei nodded slightly, today is a rare rest time in the laboratory, not the appointed time, but Zhao Heng came, there must be something, Zhao Heng guessed it as soon as Zhao Heng came.
However, Zhao Heng is so honest and direct, which makes Li Hongwei more appreciative, today's young people basically show two extremes, some people are extremely confident, even arrogant, and the other part is very inferior, inferior to the kind that they are low to the dust.
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Li Hongwei doesn't like these two, as a young person, he must have the sharpness and self-confidence that young people should have, but he can't be overconfident or even arrogant.
These two points, in Zhao Heng, are well integrated, which is also part of the reason why Li Hongwei admires Zhao Heng.
"Yes, professor, I had a patient who was infected with Naeglera fowleri, and you know, clinically, the survival rate of infection with this parasite is very low. When I was reading the literature, I found that in a case of surviving patients abroad, the attending doctor gave the patient miltefosin because the patient had skin cancer, and I wondered if I could also give the patient this medicine. ”
"Now that the patient's condition is very critical, I thought that I could use a rapid drug administration method to teach the nanotube treatment that I developed, and I think it will be just right for use."
Zhao Heng said very methodically, time is urgent, and it is impossible for him to say things little by little, he can only say that he can pick the more important and critical parts.
"Xiao Zhao, are you talking about brain-eating amoeba? And now there are more than a dozen cases of infection with that parasite in country H? ”
Hearing Zhao Heng say this, Li Hongwei said in surprise.
As a big name in the field of life science research, he has always been very concerned about this kind of news and hot spots in the biological science community.
For microorganisms, as a top biological scientist, he naturally has research, although Li Hongwei's research direction is not mainly microorganisms, but his understanding of microorganisms still exceeds that of ordinary clinicians.
"Professor, you know that, too?"
Zhao Heng was a little surprised, Professor Li Hongwei is very well-informed, although the outbreak of brain-eating amoeba on Jeju Island has been confirmed, but it is only known to a small range of people, and it is not on the news, and ordinary people do not know.
"Well, a friend in the ministry told me, so that the infected patient in China is now Xiao Zhao, and you are admitted to it?"
As soon as Li Hongwei heard that Zhao Heng had treated this patient, he immediately became interested, as a top biological scientist, he was very interested in this amoebic protozoa with a very high lethality rate.
Because in nature, scientists have such a cognition that the more deadly animals, plants or microorganisms are to humans, then to a certain extent, they can get the enlightenment of curing some rare disease of human beings.
For example, the snake venom of the highly venocious cobra is extremely toxic, but the snake venom extracted from the snake venom has good medical value and has a unique role in the treatment of cardiovascular and cerebrovascular diseases.
Moreover, the snake venom enzyme in the nerve snake venom can also be extracted from the natural anesthetic, with few side effects, and the analgesia is particularly good.
This is a good revelation, the fatality rate of patients infected with Naegria flexneri protozoa is so high, which shows that Naegleria fowleri protozoa has a special pathogenic mechanism for the human body, and once this special pathogenic mechanism is thoroughly studied, it may have some inspiration for the treatment of a certain disease.
"Yes."
Zhao Heng nodded.
"I heard from a friend in the ministry that on our side, the attending doctor found the Naegleria fowleri protozoa as soon as possible, and on the H side, it was only after our side was diagnosed that they did this kind of testing, and then the diagnosis was made. Xiao Zhao, your ability to make clinical diagnoses is also extremely strong. ”
Li Hongwei said with some sighs.
Clinical diagnosis is a very complicated thing, and it is not easy to find out so quickly that a patient is infected with an extremely rare parasite called Naegleria fowleri.
It can be said that it is precisely because our side was discovered and diagnosed first that this matter has a certain initiative.
"Actually, it is not difficult to diagnose Naegleria flexneri infection, but people don't think about it, especially the doctors in Jeju Island, when the patient was sick in Jeju Island, he was diagnosed with acute meningitis by the doctors there and treated as acute meningitis."
Zhao Heng thought for a while and said.
"I can't say that, although I don't work clinically, but I also know that sometimes the most difficult thing in clinical practice is diagnosis, and some patients may not be able to diagnose the diagnosis after going to many hospitals, doing a lot of examinations, and spending a lot of time and energy. Xiao Zhao, you were able to diagnose the patient so quickly, and it also won a head start for the ministry, which is very important in international exchanges. ”
Li Hongwei said very seriously.
"Professor, I'm afraid there are more than 10 infected patients in country H."
Zhao Heng said.
It's easy to calculate, the number of tourists received by Jeju Island was as high as 40,000 per day during the peak period, and now the tourists who have returned from there have been diagnosed, which means that there is a Naegria fuckeri in the waters of Jeju Island.
With such a high number of tourist days, there must be more than 10 infected patients.
"For this kind of thing, country H doesn't dare to break out directly, after all, Jeju Island is a tourist attraction, and once such a thing is exposed, the impact on local tourism will be fatal."
Li Hongwei said with some sighs, this is the difference in the way the two countries deal with the problem, if it is in China, this tourist destination must be shut down as soon as possible, and the relevant personnel involved will immediately conduct a comprehensive screening, and then invest a lot of manpower and material resources to deal with this incident.
But for country H, the way of dealing with it seems to be different.
At least in this processing action, this speed difference is not half a star.
"Even if it doesn't come out, then the processing speed is really too slow, I heard that the part of the examination and diagnosis is only carried out over there, and this speed is too slow."
Zhao Heng said again.
"Xiao Zhao, this national situation is different, not all national processing departments are like ours, and the safety of people's lives is the first priority."
Li Hongwei said meaningfully.
"In this way, Xiao Zhao, you want carbon nanotubes to carry the drug miltefucin, which can go directly to the lesion, so that not only the speed of the treatment will be greatly improved, but the effect of the treatment will also be enhanced."
After a pause, Li Hongwei talked to Zhao Heng about nanotherapy again.
As for the different handling methods of the handling departments of the two countries, even Li Hongwei cannot discuss this matter too much, not to mention that his status is not ordinary, and it is not suitable to discuss this kind of matter too much.
"Yes, if this infected patient wants to survive, nanotherapy is the only treatment I can think of that that will be effective."
Zhao Heng nodded and said.
As the saying goes, it is difficult for a good woman to cook without rice, and modern medicine has advantages and disadvantages, and the advantage is that a set of effective medical systems including diagnosis and treatment has been formed.
The disadvantage, that is, the treatment of patients is more limited by equipment and drugs, for example, this nano treatment, if Zhao Heng is not in the East Hospital, if he doesn't happen to know Professor Li Hongwei, even if he thinks that such a treatment method may be useful for patients, but there is no such condition.
"Without further ado, you have always had the authority of the laboratory, and you are familiar with the relevant equipment, and I am still a little urgent here, and the preparation of nanotherapy reagents can only be completed by yourself."
Li Hongwei said directly.
This modern top biological laboratory, of course, is already fully scientific and technological informatization, so it needs authorization to enter, and in terms of management, it is also all intelligent.
Li Hongwei can give Zhao Heng this permission, which can be said to be extremely trusting of him, this is a heavy trust, because in this laboratory, there are still experimental results worth hundreds of millions.
Only for Zhao Heng and Li Hongwei can they have such trust.
"Thank you, Professor."
Zhao Heng said to Li Hongwei very gratefully.
Since I met Professor Li Hongwei, Li Hongwei has spared no effort to help him.
For now, the authority of this laboratory was given to Zhao Heng, you know, in this laboratory, there are still research results worth hundreds of millions.
"No thanks, when the time comes, you can give me a copy of the treatment data, which is very helpful and realistic for the next step of nanotherapy."
Li Hongwei waved his hand, signaling Zhao Heng not to thank him, there are still many places where he will use Zhao Heng in the future, the more he comes into contact with Zhao Heng, the more he feels that an assistant like Zhao Heng is really too rare.
So now give Zhao Heng some convenience, which is also under Li Hongwei's consideration.
"There is no problem with the treatment data, and if this nanotherapy can be successful, then it can be regarded as opening up the field of nanotherapy. Moreover, this type of treatment can also be used for the treatment of cancer. ”
Zhao Heng thought for a while and said.
Mitefocin was originally used in cancer treatment, if this treatment is successful, then nanotherapy can also be used in the treatment of cancer, such a treatment method, the effect is better, the damage to the human body is less, it can be said to be a very promising treatment method.
"Yes, the current progress in the research of nanotherapy is already very good, and what is missing is clinical application. In this regard, Xiao Zhao, you have a natural advantage. ”
Li Hongwei said again.
Although this is biased, it also shows to a great extent that the purpose of scientific research is to actually use.
As a clinician and Li Hongwei as a top professor of biology, many of the results of his research are to be applied in clinical practice, so it can be said that the cooperation between Li Hongwei and Zhao Heng is deep.
"Xiao Zhao, I still have some things, the preparation of nano reagents can only be completed by you independently."
After a pause, Li Hongwei said.
It's not that apart from him and Zhao Heng, no one can operate professional equipment to make nano reagents, but that Professor Li Hongwei can completely trust the only person Zhao Heng alone.
Therefore, the maximum authority of this laboratory, Li Hongwei is only open to Zhao Heng, such a high permission, it is impossible to open it to others casually, even if it is the working researcher of Li Hongwei's laboratory, it is the same.
"Okay, Professor, go get busy. If the treatment is effective, I will record the relevant data and send it to the professor's mailbox when the time comes. ”
Zhao Heng nodded and said, Professor Li Hongwei can so readily agree to him to prepare nano reagents, which is already the greatest support for him.
Li Hongwei explained to Zhao Heng some precautions for the preparation of nano reagents, and left, while Zhao Heng came to the laboratory on his stomach.
After the scanning of the access control, Zhao Heng, who had permission, naturally directly entered the core area of the laboratory, that is, the test room for the preparation of nano preparations.
This place has always been only allowed by Li Hongwei to enter.
After all, although carbon nanotubes are used by Professor Li Hongwei for medical treatment and drug delivery, as a very useful carrier, carbon nanotubes can carry more than just drugs.
This is also the reason why Professor Li Hongwei is so cautious, such a high-end technology, if the prepared carbon nanotubes are used for things other than treatment, it will be an unpreventable disaster.