Chapter 422: Autologous tumor bone inactivation and replantation and heavy ion proton therapy
Next. Eight twenty a.m. In the office, Zhao Heng was having a morning meeting. After Li Yang, the attending doctor on the night shift, told the night shift about the situation, Zhao Heng looked at the doctors in the audience and said slowly: "What do you think about the treatment of the newly admitted Ewing sarcoma patients yesterday?" As soon as Zhao Heng's words came out, the advanced training, training and intern doctors here were silent, and the treatment of a patient with advanced Ewing's sarcoma was obviously not something that their current level could handle.
Seeing that everyone was silent, Zhao Heng was slightly disappointed in his heart, it is obviously not so easy to train a capable general, look at the current dean Liu Shangming, he has been the director of the oncology department for so many years, isn't it just a Li Haiyang?
Zhao Heng wants to cultivate the main force of a department of Li Haiyang's level, obviously there is still a long distance, and this distance is not easy to narrow.
After a while, Liu Meng said: "For now, it is to implement the radiotherapy and chemotherapy regimen set by the oncologist, strengthen the care, and I recommend some treatments that will help improve the physique." ”
"So be it, adjournment." Zhao Heng nodded, and didn't say anything more, what Liu Meng said was just a conventional way for the treatment of patients with advanced tumors, after all, most doctors in most hospitals treat it like this.
It's just that this effect is very difficult to say, and it can be seen from the low and terrible survival rate of advanced Ewing tumor.
After the meeting ended, Zhao Heng took Liu Meng, as well as a bunch of advanced studies, training and interns, to make rounds together.
To be honest, these trainees, regular training and interns have also been in the department for several days, but except for Ruan Liuzheng, no one can leave any deep impression on Zhao Heng, let alone make Zhao Heng feel like he wants to teach in person.
I have to say, talent is rare! After a while, Zhao Heng took a few doctors to the ward of Wu Yiming, a little girl with Ewing's sarcoma.
Entering the ward, Zhao Heng saw Wu Yiming lying on the hospital bed, his face was pale, and he didn't have the vitality and vitality of a seventeen or eighteen-year-old girl at all.
Seeing Zhao Heng come in, Father Wu, who was sitting on the side of the bed, hurriedly stood up.
"Director Zhao." Father Wu said. To be honest, before bringing his daughter here, he still had some expectations, hoping to create a miracle on Zhao Heng's side.
But the reality is cruel, but think about it, Friendship Hospital, as the top cancer hospital in China, has no good way there, so it can only do radiotherapy and chemotherapy, and if the effect of these two treatments is not good, it may have to be amputated.
If I changed to other hospitals in China, it was similar.
"Director Zhao, is there really no other treatment besides radiotherapy and chemotherapy?" After a pause, Father Wu asked with some reluctance.
Regarding the treatment effects and side effects of radiotherapy and chemotherapy, when I was in the friendly hospital, the doctors there had already made it very clear, to put it bluntly, that is, the effect was very poor and the side effects were very large, but at present, this is the mainstream treatment method, which is used by most cancer hospitals.
"Chemotherapy and radiotherapy are currently the mainstream treatments for Ewing's tumor, and at present, there is another treatment." Zhao Heng thought about it and said, he sat on the sofa last night and got a laptop for half a day, which is to engage in the treatment of this Ewing tumor other than radiotherapy and chemotherapy, this method is not common, and at present, it is rarely used.
"What is the treatment? Director Zhao, you said that as long as there is hope, we are willing to try. Father Wu heard Zhao Heng say this, and hurriedly continued.
During this time, he also consulted a lot of oncologists through some channels, and after consulting more, he gradually understood that for his daughter's current disease, radiotherapy and chemotherapy are, to put it bluntly, prolonging a certain life in pain, and in the long run, it is almost meaningless.
Compared with painful treatment, which can only prolong a short life, it is better to make the quality of the rest of life too high.
"At present, there is another way for the treatment of Ewing's osteosarcoma, which is autologous tumor bone inactivation and replantation." Zhao Heng said briefly.
As soon as he said this, not to mention Father Wu, even a few doctors, trainees and interns, and even Liu Meng, were at a loss.
Obviously, no one had heard of this treatment method that Zhao Heng said.
"Autologous tumor bone inactivation and replantation is to physically and chemically inactivate the residual autologous bone after the removal of tumor tissue, and then transplant it back to the human body in situ." After a pause, Zhao Heng explained.
"Director Zhao, can you be more detailed? I didn't get it. Father Wu said.
"To put it simply, it is to take out the bones with tumors to kill the tumor cells, and then transplant the bones back to let the bones start to grow again, the advantage of this is that there is no need to amputate the limbs, but at present, it is a trial stage in China, and there are no reports on the success rate." Zhao Heng patiently explained.
As soon as he said this, Liu Meng seemed to think about it, as if there was such a treatment, but several trainees, regular training and interns were still at a loss, obviously with their level and knowledge, they had never heard of this rare treatment.
"This, this bone has been taken out and disposed of, can it still live if it is put back?" Father Wu said with some doubts and apprehension when he heard this.
"Generally speaking, there are several ways to extinguish the fire of isolated tumor bone cells, such as liquid nitrogen, hypertonic saline and microwave, but these methods are very damaging to the remaining normal bone cells."
"At the medical department of Yenching University, a new heavy ion proton meter has been introduced, which can be used to kill tumor cells at a fixed point, and if these two treatment methods are combined, the normal residual bone transplanted back will have a greater chance of survival. Of course, no one can guarantee 100% success with such an experimental treatment. Zhao Heng explained.
As soon as these words came out, heavy ion protons or something, not to mention Dad Wu, but several trainees, trainees and interns were stunned.
"Director Zhao, can you please explain again?" Dad Wu continued, worthy of being the director, and the methods he used were all not mentioned by the oncologist he had seen before.
This made Wu's father can't help but have some hope in his heart.
"Heavy ions and protons are both particles, and unlike traditional photons, particles can form energy Bragg peaks, which can carry out concentrated blasting of tumors and reduce damage to healthy tissue cells."
"To put it simply, the previous extermination of tumor treatment is equivalent to bombing with bombers one by one, and this heavy ion proton is equivalent to a precision attack by a fixed-point cruise missile." Zhao Heng explained as easily as possible and said.
When protons or carbon ions are accelerated to about 70% of the speed of light by a synchrotron, these ions are ejected into the human body, and before reaching the tumor lesion, the radiation energy is not much, but after reaching the lesion, the emission will instantly release a large amount of energy, forming a name
The energy release trajectory of the "Bragg Peak" makes the whole treatment process as if it were for a tumor
"Stereotactic blasting" can kill tumor cells to the greatest extent and reduce the damage to normal tissues.
"Director Zhao, can this treatment really be done without amputation?" Father Wu couldn't help but ask. He knew that the most unacceptable thing for his daughter was amputation.
"This method does not require amputation, but because it is still in the experimental stage, it is difficult to say whether it will be successful." Zhao Heng nodded.
"Dad, I'm going to do this treatment." Before Father Wu could speak, the little girl Wu Yiming said very firmly, for a little girl of the same age, especially if she is a top skier at the national level, amputation is too cruel.
It can be said that she would rather die than have her leg amputated!
"Director Zhao, please leave it to you, no matter how successful it is, we are willing to give it a try." Hearing his daughter's words, Father Wu suddenly made up his mind, his daughter didn't want to have her leg amputated, so how could he want to see his daughter have one leg amputated.
"In the case of surgery, it will take a while to prepare, and during this time, it is better to calm down and try to recuperate your body." Zhao Heng said.
"Okay, we know, Director Zhao." Dad Wu nodded, obviously, Dad Wu had seen the world, he knew that at this time, he could only try it reluctantly, at least, when other oncologists had no solution, Zhao Heng proposed a new treatment here.
Hope is good, and Dad Wu can only think so now. At this moment, the trainees, trainees and interns standing behind them looked at Zhao Heng with admiration.
If these new young doctors still had some doubts about the level of the equally young Zhao Heng before, now this doubt has been completely dispelled.
Zhao Heng said that the two treatment methods are a combination of treatment options, and they have never heard of these two methods.
Out of the ward, Liu Meng, who was next to Zhao Heng, suddenly said with some worry: "Director, this heavy ion proton therapy instrument from Yenching University is not easy to borrow, there was a patient in the oncology department who wanted to try this treatment, but he was never ranked." ”
"It's okay, if you talk about Yenching University, I still have some way." Zhao Heng said.
"Yes, it's Professor Li Hongwei, I even forgot about this." Liu Meng then remembered that Zhao Heng and Professor Li Hongwei developed siRNA colloidal beams together, and the friendship between the two was very unusual.
"It won't be long before a few people from the open recruitment will come." Zhao Heng said slowly.
"I heard that there are four people this time, are you going to come together?" Liu Meng asked.
"It's not four, it's those who pass the written test, they will first come to the department to work for a short time, and then look at the performance and leave four at the end." Zhao Heng corrected Liu Meng's statement.
"This is what the director mentioned to the hospital?" As soon as Liu Meng heard this, he knew that this must have been proposed by Zhao Heng to the hospital, a young genius like Zhao Heng attaches great importance to efficiency and ability ratio, so he is naturally reluctant to be admitted to some people who are good at exams, but who are not good at ability.
Although the current medical doctorate, graduate and doctoral programs are basically completed in hospitals, they are actually exposed to clinical practice.
But in fact, everyone's focus is different, and some people's clinical skills are really difficult to explain.
"Corey is about to expand further, and he urgently needs a group of people with practical work ability, if a few people come in, it might as well not be recruited." Zhao Heng said.
Although the words are ugly, but the reality is so, the competition is so fierce, basically all the industries recruit people, are required to come up to work, no one has the resources and time, recruit people to slowly cultivate.
Let's just say that among these several trainees, regular training and interns, so far, Zhao Heng has not found anyone worthy of key training.
"That's right." Liu Meng nodded very approvingly, the current industry volume is so serious, there is a feeling of seizing the day, how can there be that time to cultivate slowly.
Coming out of the ward, Zhao Heng came to the oncology department. In the oncologist's office, Zhao Heng told Li Haiyang about the idea of autologous tumor bone inactivation and replantation and heavy ion proton therapy, and Li Haiyang's eyes immediately lit up.
"How can you come up with so many ways at any given time?" Li Haiyang looked at Zhao Heng and said with envy, as a doctor, Zhao Heng's flexible and keen thinking was what he envied the most.
"I just thought about it, I figured it out, what's so difficult." Zhao Heng said casually.
"Maybe this is a genius, but this heavy ion proton therapy instrument of Yenching University, it's very precious over there, last time I had a patient to use, I didn't get in line, and when I arrived, I said that a part of the instrument was broken, and I had to wait for the original factory to send it." Li Haiyang said with some sighs.
At present, the gap between domestic and foreign countries in cutting-edge medical equipment is still not small, just say that the latest high-tech products such as heavy ion proton therapy instruments can only be imported, and people only teach you how to use them.
As for what the specific principle is, or even how it is made, sorry, it is an absolute trade secret, and you don't want to know it at all, after all, it is someone else's guy.
"It shouldn't be difficult for me to contact Professor Li Hongwei." Zhao Heng said.
"That's the beauty of having a relationship." Li Haiyang said enviously. Although he can now be said to be an absolute relative of the Oriental Hospital, because his teacher is the director of the Oriental Hospital.
But this is what he got from following the teacher for more than ten years, like Zhao Heng, his development is like taking a plane.
"When the time comes, you'll need to be the main surgeon on your side." Zhao Heng said disappreciatively. Although he can also do this tumor surgery, it is obvious that Li Haiyang's level in this area is also very high, and it is not a difficult operation to remove the tumor bone.
"Okay, no problem, I can't ask for it." Li Haiyang smiled and responded, he knew that Zhao Heng came to him to bring him with him, after all, Zhao Heng was not a person who ate alone.
Such a highly experimental operation, especially for oncology, is very difficult for oncologist Li Haiyang to encounter, and it is also a very precious surgical opportunity.