In the second official medical office of Jingzhou, in the deepest part of the medical office, there is a courtyard, which is heavily guarded outside, and it is a hidden silkworm house during the period.

Pingsuli, only Zhang Zhongjing, and a few of his direct disciples Wang Shuhe, Du Du, Wei Xun, and Diao Chan are allowed to enter...

Because of this, the entire government and medical offices, whether doctors or patients, are not allowed to enter here.

For this reason, it has also become the most "mysterious" place in the mouth of those young doctors in the medical department.

At this moment, Diao Chan stayed alone in it, and in front of her, dozens of oranges had grown thick moss on their skins because of more than ten days of drying.

The sable carefully placed the moss in a container and then filled it with brine to isolate the hyphae from the moss.

The soaked debris is sifted out through salt water to remove the mycelium.

Next comes the most important step...

Diao Chan poured a bottle of red tar-like liquid into the container and stirred it quickly with the moss.

This process is extremely cumbersome...

She stirred a stick of incense for a whole time, not fast or slow, always consistent.

The red tar-like liquid is none other than a liquid extracted from wood in another process.

If you follow the "step diagram" left by Guan Lin, this liquid is called - wood tar!

The specific steps...

It is to put the wood into a closed environment, and then roast it over a high fire, which is called "dry distillation of wood" in the step diagram, and at the end of the dry distillation, you can see the red tar-like substance, as well as charcoal, this red substance is called wood tar!

Diao Chan didn't know that the main ingredient of this "wood tar" was "wood creosote oil", and the smoke in the confined environment was wood gas, whether it was liquid or gas, it contained the most critical substance in the "step diagram" provided by Guan Lin - methanol!

The substance that dripped into the moss and then quickly stirred was this methanol.

As for the stirring of moss and methanol, it is for the extraction of "penicillin"!

Needless to say, penicillin is important.

Especially in ancient times, if you encountered a bacterial infection, it was only a matter of resignation.

If you can carry it, you will escape, but the result of most people is often wound infection, bacterial attack, and death!

The emergence of penicillin solves this big problem of "bacterial infection"!

After doing the previous steps, Diao Chan has come to the last step, thanks to her following Zhang Zhongjing for so many years, she has an in-depth understanding of medical science and pharmacology...

But even so, she still didn't dare to be careless at every step.

At this moment, Diao Chan gritted her teeth, she had already prepared a distortor made of black carbon and sand nets, and thoroughly considered the last liquid in the moss with a layer of black charcoal, removing mycelium and other solid substances, leaving the purest liquid.

It wasn't until this step was completed that she had her hands free to wipe the beads of sweat from her forehead...

Of course, this is not the complete process of penicillin extraction.

The last step is to pour the penicillin extract into a shallow dish and let it dry in the air.

The whole process lasts for several weeks until the dry penicillin is left at the end.

It's just that this time takes too long, so according to the guidance on the "step chart", Diao Chan first tried to use liquid on the small animal...

See if the sores from small animal infections can get better.

Outside the door, Da Qiao was already waiting here.

Speaking of which, since Da Qiao settled in Jiangling, he has met Diao Chan, a close friend who "has a similar experience", and has seen his daughter who has been missing for many years, and even heard that his son Sun Shao also defected to Guan Sigongzi and fled from the land of Dongwu.

It's a wish fulfilled...

So, it's quite boring to do nothing all day, simply... I followed Diao Chan to learn medicine, but medicine and pharmacology are broad and profound, and you can learn it in a moment.

It just so happened that Guan Lin left Diao Chan a scroll of step diagrams and gave her a task of refining "penicillin", and Diao Chan asked Da Qiao to help when she lacked manpower.

Of course, Da Qiao doesn't know medical science, and she can't help much with refining "penicillin", but... Let her use the refined "penicillin" to try it for the small animal, which is relatively simple.

It's just that in this way, it has only been a month, and Da Qiao's hands are stained with the blood of "small animals".

You must know that even if Guan Lin left the specific steps of "local method of extracting penicillin", theory is theory, and practice is practice, which is completely incomprehensible.

For example, along with penicillin, there is also a substance called "patulin", which, like penicillin, is produced by molds that parasitize the surface of fruits.

Penicillin is antibacterial, and patulin is more antibacterial than it;

Penicillin is soluble in water, and patulin is also soluble in water.

But the biggest difference between the two is that penicillin is an antibiotic, while patulin is a toxin, and the final result cannot be distinguished by the naked eye.

Of course, according to Guan Lin's memory, it has been mentioned in the step diagram that the use of "orange and citrus aurantium", a fruit that is not favored by penicillin, should be selected as much as possible when selecting strains.

Actually, there's another one...

The safest thing is to train two generations...

But this was completely unrealistic in ancient times, and there were no conditions for incubating two generations.

The difference between "penicillin" and "patulin" is actually just one of the many pits in the penicillin refining process...

Otherwise, there would not be a large number of large animals that died at the hands of Diao Chan.

"The previous three white rabbits are dead... The potion that was smeared yesterday was just now... All dead... It's miserable. ”

Big Joe took the latest vessel containing "penicillin" and reminded Diao Chan softly.

"So fast?" Diao Chan bit her lip slightly...

Through a large number of rabbit attempts, she discovers a serious problem.

If penicillin is not used correctly, it will die instantly.

This is because the "penicillin" is never pure enough in the process, or mixed with impurities...

In case of infection, hard resistance is stronger than trying crude penicillin...

After all, there is still a chance to survive the hard resistance, and trying crude penicillin is undoubtedly a race against death!

"Did you fail again?" Diao Chan sighed helplessly.

In fact, she did not only try this way of refining "penicillin", such as stirring moss with rapeseed oil, mixing it with black charcoal powder, then wrapping it in gauze and washing it with spring water.

Another example is to mix rice into juice, use taro juice as the culture medium, implant Penicillium for seven days, filter with cotton filter, add rapeseed oil, use the water under the oil to dissolve penicillin, and then worry...

But either way, it seems, she failed.

Even, not only can't save people, it's even fatal!

"Alas..."Thinking of this, Diao Chan felt that he had been busy for more than a month.

"But there was a red rabbit whose wound was healed, and there were no more abscesses..."

Not...

With Da Qiao's words, Diao Chan's originally languishing and annoyed mood changed completely...

"What about the rabbits?"

"In... Still in that silkworm room! I just saw that I can already jump..."

"I'll take a look..."Diao Chan's whole body became excited, as if at this moment, everything she had done these days suddenly had meaning.

It also proves that the "step map" left by Yunqi Gongzi is effective, and it is possible to cure the extremely terrible "abscess" of this era!

…

…

Shouchun City, Cao Cao has returned.

Outside the city gate, except for Cao Zhen with a few horses, no one greeted him, and no one even knew that Cao Cao was returning today.

Two rows of tiger soldiers lined up on either side, and Cao Cao walked out of the carriage with dignity.

It's just that after all the fatigue along the way, after all, this old man who is over sixty years old still can't bear it on his body.

He is no longer the Prime Minister Cao Cheng who once galloped on horseback and took "General Zhengxi" as his grand wish!

Cao Zhi supported his father, and Cheng Yu walked last.

"Prime Minister."

Seeing Cao Cao, Cao Zhen immediately greeted him.

Cao Cao stopped, revealing a pair of tired eyes, "Zidan, tell me, is Huainan okay?" ”

"Thanks to Prime Minister Huwei, the Jiangdong rats dare not come to attack!" Cao Zhen replied, speaking of which, he gently raised his eyes and glanced at Cao Zhi, and saw that although Cao Cao was very weak, he still cared about and cared for this son, and even the weight of his body was reluctant to press on Cao Zhi's side.

Such a loving act made Cao Zhen feel very worried for Cao Pi.

It's just that this worry only lasted for a moment, and he hurriedly raised his hand and said softly: "There are still a few things to report to the prime minister." ”

"Say!"

Cao Cao sat at the stump on the side and listened patiently to Cao Zhen's report.

Cao Zhen said truthfully: "The first thing is that I just received information that Zang Ba, the lord of Langya Country, has already led his troops to Nanyang, and in addition, the families of these soldiers are also moving to Nanyang in batches. ”

Although it was to clarify the facts, this incident made Cao Zhen's eyes faintly worried.

"Lone doesn't plan to let Zang Ba be the lord of Langya again, as long as he can block the offensive of the Guan family Shilang, and stop the Jingzhou soldiers from the country for Lone, Lone plans to seal the entire Nanyang to him... Let him be the lord of the southern capital! ”

This...

Cao Cao's words made Cao Zhen subconsciously experience a deep compromise.

A corner of Langya, how can it be compared with the vast Nanyang, Nanyang has rich acres of land, is the economic center of the north and the Central Plains, and Emperor Guangwu started here!

- "Nanyang... Nanyang, the prime minister would give in to such an extent, is the prime minister jealous of that Guan family Shiro?"

Don't wait for Cao Zhen to groan...

Cao Cao's words came out again, "Back then, Lone occupied Yanzhou and had a bad relationship with Yuan Shu and Lu Bu, so he called Liu Bei to Xuzhou and let him stay in this middle military buffer zone.

Speaking of this, it seemed that suddenly, Cao Cao's mind had the voice and smile of an old man.

also emerged his sonorous and powerful words that helped Cao Cao dominate the Central Plains:

- "This is a plan to drive away the tiger and devour the wolf!"

This made Cao Cao suddenly fascinated...

"It turns out that the prime minister has already made arrangements..."Cao Zhen continued, "Just yesterday, General Xiahou sent another urgent letter from the north, and under the order to recruit widows, he recruited another 30,000 new soldiers!" Now I am stepping up my training, and I will rush south within a month..."

Hearing this, Cao Cao bowed slightly, not leaking joy and anger.

30,000 soldiers, although the number is a lot, but they are new recruits...

In today's situation, what Cao Cao lacks most is veterans, experienced veterans...

3,000 veterans, each of whom is long, can train a new army of 30,000 people who will come to fight overnight, but without these 3,000 veterans, the recruits are just a basin of loose sand.

But now...

Cao Cao's ace legions "Tiger and Leopard Cavalry" and "Runan Soldiers" were burned to death, shot to death, surrendered, and rebelled, and there are not many veterans under Cao Cao who can really be entrusted with important tasks!

Cao Cao pondered for a moment, as if he had made a certain decision, and he immediately ordered: "Tell Xiahou Yuanrang and let him hand over all the recruits of 30,000 people to Pang Lingming, I heard that Pang Lingming's poisonous arrow hit Guan Yu, and so far Guan Yu has not been able to heal, this is a great merit to protect Xiangfan, and it should be rewarded, in addition, he will be crowned as the general of Zhennan, and he will eat two thousand!" Tell him that as long as he can keep Xiangfan, he still has a lot of canonization in his lonely hand, and he can give it all to him! ”

Cao Cao was canonized in this way, and Pang De jumped from the original miscellaneous general to the "Siping" and "Si'an" generals, and directly became one of the generals of the four towns, only one step away from Zhang Liao and Zhang Wenyuan's official title of "Four Expedition Generals".

This is enough to show that Cao Cao attaches great importance to Pang De.

Not to mention the "Lord of Nanyang"!

It's a huge pie!

But Cao Cao was also helpless.

After the death of Manzhong, Wenpin, and Le Jin, Li Dian was captured, and Zhang Liao's whereabouts are unknown.

"Whoa..."

Cao Zhen hurriedly surrendered his hand, "The last general will send someone to pass on the prime minister's dictation, let Shang Shutai draft the canonization, and the Son of Heaven will stamp the seal, and then ask General Xiahou to hand over all 30,000 recruits to General Pang De." ”

Cao Cao squinted, and he groaned in his heart.

- "Xu Gongming defeated first and then won, Zixiao just woke up, and the situation in Xiangfan is all in the hands of Pang Lingming!" Ling Ming, don't let Gu down!"

Cao Cao is now extremely important and trusts Pang De, just as he used to unconditionally trust and reuse Zhang Liao and Zhang Wenyuan.

Speaking of this, Cao Cao got up slowly, almost rested, and prepared to enter the city.

Cao Zhen reported again, "Prime Minister, there is one more matter, an important matter. ”

"Say!"

"It's General Wen Yuan, he's back!" Cao Zhen hurriedly told Cao Cao the news of Zhang Liao's return.

is also this sentence, Cao Cao, who was originally tired, suddenly mentioned twelve points of spirit... He shook Cao Zhi away, his eyes widened, if Fang is the squinting eyes, then now the eyes are wide, the eyes are tigers...

It seems that Zhang Liao's safety and well-being made Cao Cao feel rejuvenated in an instant.

"Where's Wen Yuan?" Cao Cao hurriedly asked.

"General Zhang had many sores all over his body, and according to what he said, he also fell into the fat water..."Cao Zhen explained in detail: "However, General Zhang has treated these wounds by himself and burned them with a soldering iron to stop the bleeding. ”

"Lead the way ahead, take Gu to see Wen Yuan..."Cao Cao no longer had the patience to continue listening, and immediately instructed Cao Zhen, he was eager for Zhang Liao's return.

Cao Zhen hurriedly led the way...

But after only a few steps, after Cao Zhen hesitated repeatedly, he couldn't help but turn around and speak to Cao Cao, "Prime Minister, there is something that 'Zhen' must tell the Prime Minister." ”

"What's the matter? It's even more important than seeing Wenyuan alone! ”

"It matters." Cao Zhen accentuated his tone, and his tone became meticulous: "General Wenyuan returned from injury, and the last general talked to him and asked what happened to General Wenyuan, but Wenyuan's three armies went around his mouth three times, and he was left and right... Therefore, the last general was a little worried, for fear that someone would bewitch General Wen Yuan, so he sent someone to investigate against the way General Wen Yuan returned! ”

"The result?" Cao Cao's footsteps paused, he was suspicious by nature, and when he heard such words, it was inevitable that the doubts in his heart would not be aroused.

"The last general found out that General Wen Yuan went up to Bagong Mountain, and the same... There was also a person on Bagong Mountain, and after the last general inquired, he found out that it was actually the young general of Eastern Wu - Ling Tong! The last general thinks that my Great Wei and Eastern Wu are in the same boat, how can General Wenyuan..."

When Cao Zhen said this, Cao Cao was furious, he subconsciously raised his hand and directly knocked down Cao Zhen with a slap.

"Get out—"

Cao Zhen suddenly woke up, he knew that what he had just said... Most of the reason is that the prime minister has noticed the intention of provoking.

In the face of Cao Cao, who was furious, Cao Zhen didn't dare to explain more, and even retreated.

After Cao Zhen left, Cao Cao's tiger eyes loosened slightly, and Fang Cai's anger immediately dissipated invisibly.

He glanced at Xu Chu, and Xu Chu approached Cao Cao.

Cao Cao whispered, "Spread the news of this slap of the lonely fan Dan..."

Xu Chu immediately understood, and hurriedly surrendered his hand, "Prime Minister rest assured." ”

I'm turning around to make arrangements.

Cao Cao hurriedly shouted to him again, "Wait", his voice continued, but it became much softer and more cautious, and his tone became a little more suspicious and hoarse.

"Fang Cai Zidan said, Wen Yuan and the Eastern Wu general Ling Tong appeared on the Bagong Mountain together, you go to investigate this matter, send a trustworthy tiger soldier to investigate, but tens of millions, you have to check secretly-"

As soon as these words came out, Xu Chu was also stunned, and he raised his head to look at Cao Cao in surprise.

It seems that in an instant, the one he is most familiar with, the suspicious Prime Minister Cao Cheng, is back, just like the sentence "I'd rather bear the world than the world!" ”

Even if the object is Zhang Wenyuan this time, Cao Cao, as always, is like this.

At this point, Cao Cao's cheeks had turned to the other soldiers, and his tone returned to the most urgent concern for his subordinates.

"Lead the way ahead, quickly, lead the lonely to see Wenyuan-"

After such a sentence, Cao Cao seemed to think of something again, he looked back again, looked at Cao Zhi, and added, "Zijian, then Sima Zhongda, you go to trial, whether you kill or chop, it's all up to you-"

Speaking of this, Cao Cao did not hesitate, turned over and got on the horse, and the horse took four or six steps that he did not recognize, and walked away.

…

…

Jiangling City, Jingzhou Second Official Medical Office.

Guan Lin has just arrived here.

He didn't stop, and directly took Zhang Xingcai, Shiwu... Together with Zhang Zhongjing, who was late, he walked to the secret room in the back hall.

In the courtyard, there are a few poor rabbits, I don't know who got hurt, and I don't know how the wound became infected!

Of course, in addition to rabbits, there are a couple of dogs ... The same is true.

They are the losers in the extraction of "penicillin".

"Looks good..."

Guan Lin was quite relieved to see the rabbits and dogs here, thinking... Penicillin was a great success.

Who would have thought that at this moment, Diao Chan and Da Qiao hurriedly walked out of the house.

"And it was a great success..."

Diao Chan pointed to a red rabbit in the rabbit cage, "Except for it, all the rabbits and dogs here are newly replaced, and they have never been medicated..."

Yes...

Guan Lin was stunned for a moment, and hurriedly asked, "What does Senior Sister Ren mean... What about the other rabbits and dogs? ”

"It's all dead," Diao Chan said with some frustration and regret.

Then she pointed to the red rabbit again, "But thankfully, it's... It seems to have come back to life, and the sores have healed! At the very least, it proves that this method works! ”

This one...

Hearing this, Guan Lin realized a serious problem.

This special meow is "I don't usually burn incense, and I temporarily cram Buddha's feet"...

Guan Lin found that he was still too naïve, extracting penicillin and using penicillin to cure the infection of the wound, only a month, and he still unintentionally inserted willows, and the time was still too rushed.

With this in mind...

Guan Lin raised his eyes to look at the red rabbit that was jumping alive because of the healing of the wound, and couldn't help but sigh in his heart.

- "Penicillin, my dad's 'face', it should be... It's not that red, is it?'

- "If that's the case, then you can only follow the second plan, and you have to put the 'ultimate'!" Eventually... I'm going to have to make you look good!'

…

…

(End of chapter)