Digitalis and belladonna are the only natural botanicals in hand that can really confirm their effectiveness, and the mechanism is relatively clear.

The former are fresh plants that have been recently harvested; The latter is a souvenir from Westminster's visit, dried and preserved, perhaps mixed with a few blueberries that were not picked out.

Of course, when they were still fresh and could see the difference, Kraft didn't have time to discern them carefully. When it dries, it can only be said that it is exactly the same thing, similar to strawberry seeds falling into a pile of white sesame seeds.

Fortunately, there are no precision requirements now, and I believe that the sample will not mind whether the reagent belt has a fruity aroma.

Take two teaspoons of dried fruit and bring to a boil with the remaining hot water. The shriveled fruit swells and the liquid is stained with a shiny light purple color, which looks beautiful in a transparent white glass container.

In fact, when belladonna appeared at banquets, it was not all the work of the Assassins, and it also became a dangerous cosmetic.

Because of Kraft's incomprehensible aesthetic, some people insist that larger pupils make them appear more attractive and attractive, and that one of the prodigies discovered that belladonna poisoning causes pupils to dilate.

As a result, belladonna eye drops have become a popular beauty product, and a small drop before the appearance can have large sparkling and attractive pupils. Although there are always accidents with varying consequences, there are still only a lot more fans.

This is probably one of the earliest examples of medicinal use of belladonna, which explains its pharmacological mechanism well, i.e., anticholinergics. Because cholinergic receptors are widely distributed in many smooth muscles and glands, belladonna has a very large range of effects.

The pupillary sphincter, which controls miosis, is certainly one of them, and it has to be said that topical use as eye drops is a relatively sensible way to use it – and the most sensible way is not to use it blindly. "Blindly" can be used in a literal sense here.

Kraft sucked a small amount through a feather tube and dripped it onto the sample that had returned to normal, and the unkeratin-free surface quickly absorbed the liquid, and the purple color soaked into the translucent soft body, slowly spreading and fading.

Following the color diffusion trajectory, you can see some small capillary tubes that are not visible when the color is not developed, and the absorbed liquid is transported along with the pipeline system, which quickly penetrates the corner of the sample and then comes to an abrupt end.

With a small but complex period of fluctuations, the flow of bodily fluids is suddenly stuck. It seems that the valve in the tube is closed, forcibly confined the drug to a certain range, and the diffusion rate is greatly slowed down.

"Is this all right?" In a normal vessel, the valve is supposed to act as a one-way valve to prevent blood from going retrograde, but in the sample, this simple structure seems to have been modified to allow for controlled opening and closing as needed.

You can choose to control the poisoning locally, instead of being like a person, and after absorption, it will spread throughout the body after blood circulation.

Kraft tried to pour in more liquid, but instead of absorbing it, Kraft formed the same cuticle that it had before, isolating itself from the outside world.

This did not dampen the professor's determination to continue the experiment. Since it doesn't absorb, inject the drug into it.

He didn't have a syringe in the strict sense of the word for the time being, and he hadn't thought of asking for one before. In his view, there are basically no drugs suitable for injection.

Unfortunately for patients, the concept of intravenous administration predates the emergence of drugs suitable for intravenous administration.

Attempts have been made to speed up the onset of action by injecting drugs into blood vessels, but not with syringes. Theoretically, all that is needed is a thin tube with a pointed tip and a vessel that can provide pressure.

"Next time, I should really ask the Xiguo family if they can make syringes, and digitalis will let them agree." With limited conditions, Kraft used the forerunner syringe provided by the clinic – a skin made from an animal's organ that temporarily stored liquid metabolic end products.

"Well, that thing looks a little bit like that." Koop felt that the shape of the tool and the way it stored were a bit unpleasant.

"You're right, I'm asking for it, and David won't be able to use it on patients." Kraft attaches the needle to the balloon, aspirates the belladonna solution, and injects the liquid into the sample.

In order to prevent the difficulty of diffusion, he deliberately injected at different points and at different depths.

The spheroids, which were completely stained with light purple, contracted violently, and the frequency increased significantly, but the internal digestive vesicles became stagnant and sluggish, and some parenchymal particles and small lumps of different colors proliferated and enlarged, and their supply was maintained by abundant neovascularization, which was suspected to be a compensatory enlarged secretory gland.

It was almost as expected, and it was a compound fluctuation under the vision of the spiritual senses, which could not be resolved. Presumably, the target receptors are ubiquitous, causing the whole body to be adjusted.

It took some time for the sample to adjust, and the fluctuations were even stronger than they would be in the heat, but they were also more chaotic.

In response to the imbalance of different systems caused by the same drug, it has chosen to simply respond with multiple pathways changes.

The assistant noticed the professor's seriousness mixed with bewilderment and a little disappointment.

"Purple bell flower stems and leaves juice, hurry up." He commanded. The hourglass was no longer turning, but it seemed like some other timer was rushing.

"Wait a minute, you'll be fine." Coop tosses the whole plant into a washboard-like juicer, presses it down to squeeze out the fresh juice, and bottles it for the eager employer.

After a simple four-fold dilution modulation, digitalis injection is squeezed into the freshly calmed sample.

Unlike the brightly colored belladonna tea, the pale yellow-green solution is difficult to distinguish after entering, and there is no way to trace the trajectory.

Kraft subconsciously stared wide-eyed for the result. As time passed, the familiar pain and discomfort were unexpectedly less severe, and on the contrary, an unsettling sense of ease was growing.

It should be almost time, but the feeling is not there yet, and he wants to see it again.

The specimen's overall movement slowed down, but the amplitude became larger, as if from a short gasp to a deep breath, and the rhythmically moving bundles of muscle fibers forcefully pulled the surrounding tissues and contracted inward.

The intensified contraction squeezes the body fluids in the tubing and pumps them to all parts of the body at high speed, affecting more muscle bundles, so the contraction is more forceful.

When this trend reaches a certain limit, the situation is reversed, and the frequency of relaxation begins to increase and the intensity becomes weaker.

When the frequency reaches a certain level, the scale of contraction is reduced to a very undesirable degree, and it is not so much a contraction as a spasm and trembling, and high-frequency shallow contractions can no longer effectively produce pressure.

What happens in people also appears in the sample, in a similar way.

This would be a good teaching aid if it was used to explain the electrophysiology of cardiomyocytes. The contraction of myocardium needs to maintain a certain difference in the concentration of ions inside and outside the cell, and the inhibition of the sodium-potassium pump of digitalis will destroy this state due to the change of potassium ion concentration after reaching a certain level, resulting in a decrease in resting potential.

For those who happen to remember a little bit of the electrophysiological basis of cells, it quickly comes to mind what this means – increased excitability.

It is manifested in the heart, that is, faster and faster, when it reaches a certain point, like a convulsion, its contraction no longer produces effective pressure, just like a constantly twitching hand cannot lift anything.

【Ventricular fibrillation】

The most lethal arrhythmia is formed, and the whole process is visualized. The professor glanced at Koop regretfully, but unfortunately the only teachable object here was nowhere near that level.

"Let me see, what are you going to do now?" Kraft observed the specimen with great interest, his attention raised to the extreme.

The entire circulatory system of the specimen should have been completely shut down by now, and it would be useless to create any new tissue, unless it could reverse this critical problem.

His expectations were answered.

A new wave spilled over from the moon remains, not necessarily strong, but not accompanied by too much clutter, so that it stood out for a brief moment and reached a recognizable level.

The mental organs, which are always ready, perceive it, and inscribe this ripple, which cannot be described in the form of other senses, into a sophisticated memory.

To the naked eye, the twitching of the internal bundle branches of the specimen is controlled.