Chapter 766: Genetic Chimerism
Although the private prison in the United States is indeed rotten, the management of the state prison is obviously not so bad that the felons are impersonated, and when Jack and Jubal arrive at the state prison, they see Kerry McMay himself.
"So what the hell is going on?" Jubal, who was scolded by the other party, did not get angry because of this, but was more confused and uneasy.
"Let's go to the CSI laboratory and ask, what reasonable explanation may be given for the DNA identification they made." Jack probably has some ideas, but he still needs the help of a professional.
Around noon, the two found Mike Taylor in the director's office, who was sucking instant noodles.
After nibbling on the sandwich he bought on the way to the aroma of instant noodles, Jack explained his intention, "Hannah is on her way to contact McMae's sister, ready to ask her if McMae has made a bone marrow donation before.
I know that bone marrow transplants can lead to the development of gene mosaicism, but doesn't this usually happen only in the blood? ”
Chimera is used in genetics to denote individuals with different genetic traits that are chimeric or mixed, and the English word seems more intuitive, chimera, a monster with a lion's head and a sheep's body and a snake's tail in ancient Greek mythology.
The phenomenon in which a normal person carries at least two sets of DNA is called the "Chimera phenomenon", and fraternal twins form two separate embryos when they are developing normally in the mother's body.
However, if there is a lack of maternal support or other reasons that may cause one of the embryos to die, the other surviving embryo will absorb it, and the embryo will grow up to become a chimera.
Another way to cause chimerism is bone marrow transplantation, which is a very effective treatment because the cause of leukemia is a problem with the patient's own hematopoietic function.
The transplanted bone marrow contains other people's hematopoietic stem cells, which is equivalent to the patient's own hematopoietic stem cells being replaced by others, so the patient's blood cells will contain the donor's DNA.
This is also where Jack wonders, they have basically ruled out the possibility of Kerry McMae having an identical twin brother, so the only possibility seems to be a bone marrow transplant.
However, the DNA samples used by the CSI laboratory for DNA testing are not the blood of the murderer, but the epithelial cells on the surface of the skin.
Mike Taylor pondered for a while, and then called up a document on the computer, "In fact, not only epithelial cells, but also the donee's semen and DNA in the epithelial cells may be replaced by the donor's DNA."
This is a case in Wausau County, Nevada, where a man named Chris Lang received a bone marrow transplant eight years ago for acute myeloid leukemia and myelodysplastic syndrome.
Within three months of successful surgery, the DNA in his blood was altered, and DNA from the donor was subsequently found in swab samples taken from his lips, cheeks and tongue, and four years later, the DNA in his semen was replaced. ”
"Ugh me. Is it true that you're talking about it? "Jubal is also a highly educated person, and although he can't interject the whole time, he does understand it in general.
"So your instinct is right, in that case 3 years ago, Kerry McMay really wasn't the murderer." Jack smiled and reached out to shake him.
Jubal had mixed feelings for a moment, and he didn't even know whether it should be joy or sorrow.
"Don't think too much, the responsibility is not on you, and it won't even affect your partner, this kind of thing is too rare, it is a non-subjective factor, you may not be too clear in your mind at that time, but there is nothing wrong with the whole case handling process.
What we need to do now is to correct that mistake as soon as possible and catch the real culprit before the next victim appears. ”
After saying that, Jack thanked Mike Taylor and left the CSI lab with Jubal, and before they could return to the Federal Building, Hannah called, and she had already received confirmation from Kerry McMay's sister that he had indeed donated bone marrow once when he was 20 years old.
"So all we have to do is find the recipient through the medical records, Isobel, immediately apply for a search warrant for access to the relevant medical files, and we need to catch the Gou Niangyang before the next victim appears." ”
Isobel, who was waiting at the door as if to greet the two of them, showed a strange smile, "I think we may have found out who the murderer is." ”
"Is that the children's hospital volunteer who claimed his vehicle had been stolen?" Unlike Jubal, who was full of emotions and thoughts along the way, Jack had already roughly guessed the identity of the murderer on the way back from the two.
Among the suspects currently under investigation, it just so happens that this guy has had leukemia.
There's a hint of undisguised appreciation on the smile on Isobel's face, "Yes, we've captured quite a few portraits from the ATM machine across the street from Sigby's café, and the time is about ten minutes before the suspicious computer logs into a website in the café.
Originally, we were just trying to find a few frequent faces and investigate the identity in detail, but Aubrey recognized the Pete de Leon at a sight. ”
There was no one in front of the big screen in the operations center at this time, only the photos and materials of Pete de Leon were still on the screen, a fat white man with brown curly hair, who looked safe and harmless, and the smile on the photo was also full of warmth, which was quite ironic.
"After receiving your phone call, coupled with these photos, we found out what was going on, and I contacted the judge as soon as possible, and the local police have arrested Pitt de Leon, and Aubrey can bring him back in an hour at most, and Hannah and Jiejie are on their way to search his apartment."
Isobel explained what had happened and what she had planned.
"Looks like you're comfortable with your job." Jack complimented Isobel.
Jubal rubbed his hands together and asked with a little hesitation, "Can I be in charge of the interrogation later?" ”
Jack almost didn't laugh out loud, "Have you forgotten that you're still the boss of the operations center?" ”
After two days of observation, he had confirmed that Jubal had indeed quit drinking, and that he had not drunk a drop of alcohol, which was quite an easy task, and it seemed that those things had indeed taught this old man a profound enough lesson.
While Jubal waited for more than an hour, an energetic Aubrey escorted Pete de Leon into the interrogation room.
Jack didn't participate too much in this case, from the scene investigation, analysis and reasoning to the final revelation, it was basically completed by teamwork, and he only played a role as a catalyst at most.
The performance of the crowd was also very satisfying, and it could even be said that it far exceeded his expectations, and Jack stood in the observation room, watching Jubal and Aubrey enter the interrogation room together, and his heart was secretly proud.
"I'm Agent Valentine." When he walked into the interrogation room, Jubal seemed to be a different person, and threw a pile of documents on the table with a serious face.
Pitt De Leon, whose hands were cuffed to the table, habitually smiled all over his face, without the slightest uneasiness, looking harmless to humans and animals, and even his voice was still slow, as if he was afraid that others would not hear clearly.
"Can anyone tell me what's going on?"
Jubal asked a question as he paced slowly, walking behind him, speaking without any ups and downs in his tone, "Did you have acute lymphoblastic leukemia when you were a child?" ”
Pete DeLeon moved his cuffed hand as if he felt a little uncomfortable, and the smile on his face remained unchanged, as if some solidification magic had been applied, "Is there something wrong with this?" ”
"And then you had a bone marrow transplant, and the guy who was matched with you, who was not related to you in any way, but the operation was successful, and you could almost say healed, right?" Jubal continued.
"Yes, how do you know that?" Pete de Leon looked at Aubrey standing in the doorway, and then turned to look at Jubal with a curious expression.
(End of chapter)