Chapter 379: The Secret of Longevity
After staying in the prairie for a few more days, Ye Li is about to return to the West, of course, Ye Xing is a full-time driver, but this time she brought Ye Xiaozi and Ye Xiaoming, oh and the white fox.
The two eldest children are already in their twenties, in fact, they are not young anymore, standing in front of their parents, they are like brothers and sisters, just because the two of them have cultivated since childhood, and they look relatively young.
In the East, the two should have talked about marriage a long time ago, but the two are cultivators, and they really can't ask for this, the key is that with the arrogance of the two children, it is estimated that it is difficult to find a suitable candidate.
A day later, back in Lanbo City, Ye Xing gave the two children some newly refined foundation building period pills, as well as some self-defense equipment, and let the two of them travel.
Ye Xiaozi and Ye Xiaoming now have the cultivation of the sixth layer of the foundation, and they have a new type of spiritual qi gun for self-defense, Ye Xing is not worried about the safety of the two.
Moreover, now that Ye Li is in charge of the secret guards, all over dozens of countries in the Far West, as long as she wants, she can quickly get the exact whereabouts of the two of them, and the key is that the two of them have long-wave phones with them and can contact them at any time.
As a person who shakes his hands, Ye Xing no longer cares about anything in the Lixing Group at all, he basically stays in his own laboratory, doing that biotechnology research.
Ye Xing has analyzed the cell structure of hundreds of species of animals and plants, and has conducted the most detailed research on various human bodies in this world, and has also had a genetic map of human beings.
The research that was interrupted by various things was picked up again, this time, Ye Xing asked everyone not to disturb, determined to figure out the mechanism of life aging, and it was best to prepare a drug that could keep him young forever.
The reason why this research was done first was also requested by Ye Li, she was forty years younger than the Qin sisters, but it seemed that she was still a little older than the two daughters.
Ye Li has been nagging about this matter, and it is also the only thing she is dissatisfied with Ye Xing, always teasing Ye Xing, and saying that she is a miracle doctor?
Ye Xing also saw the desire of his daughter Ye Xiaozi, in fact, women want to be young and beautiful forever, Ye Xiaozi and her mother stand together, they are definitely sisters.
But for a while, you can't go back to the small space of the elixir, and if you go back, you may not know what you have eaten, so that the four of them will not age for a long time.
Thinking that I have the scientific and technological knowledge of the earth in my previous life, I am actually clear about the mechanism of cellular aging, and now if I compare and study the mechanism of cells, I can also make anti-aging drugs.
Another reason, which made Ye Xing even more determined, was that Ye Mu's face was already extremely old, and her body seemed to be okay, but she was nearly ninety, and her face was extremely old.
There are certainly no immortal people in the world, but it is also good to make life more beautiful and beautiful when you are alive.
At the same time, it is also what Ye Xing wants to do, besides, this really involves the improvement he is researching, the efficiency of the conversion of spiritual qi into true qi.
It took twenty days to build a new laboratory in a cave in the back mountain of the Royal Academy, and set up the most tightly protected formation.
Such strict security measures are not because of confidentiality, but because Ye Xing has raised a lot of small animals in it, all of which are here for experiments.
Biochemical experiments are extremely dangerous, and if one is not careful, it is very likely to cause a terrible disaster, and he does not dare to mess around, at least he has to be extremely cautious.
It's really not a fool's errand, from the memory of the superintelligence, Ye Xing found the biochemical knowledge that had already been understood and solved on the earth in his previous life, and then compared and studied the life in this world.
The earth technology of the previous life has clearly understood all the biochemical processes of life's birth, growth, and aging, and has corresponding countermeasures, but now it is just a new experiment, detection, and comparison according to the characteristics of life in this world.
From the knowledge reserve of superintelligence, Ye Xing is completely clear that the reason why the cells of the main life forms on the earth will age is actually caused by several mechanisms of biochemical processes inside the cells:
1. Aging caused by DNA replication, lack of telomerase activity in cells, and gradual shortening of telomeres with the increase of cell division times, that is, DNA is damaged, so that DNA cannot replicate normally.
Telomerase deficiency also significantly increases the content of intracellular inhibitors, which in turn induces the expression of intracellular viability factors, which over-activates intracellular biochemical processes and triggers cellular senescence.
2. Environmental stress-induced aging: external stress conditions can also shorten the life span of cells and promote cell senescence, mainly oxidative damage, which is caused by damage caused by the active oxidative components metabolized in life activities.
3. The telomeres become shorter every time the DNA is replicated, which is manifested by cell division once, the telomeres are shorter, and the telomeres slowly disappear when the number of divisions increases, and when the critical point is reached, the telomeres cannot protect the DNA, resulting in the DNA replication errors described above, resulting in the appearance of mutant cells.
4. Mutant cells will activate the expression of another inhibitory enzyme, thereby inhibiting the cell cycle, causing the cell to enter senescence, and the cell will soon apoptosis.
5. When cells are damaged or mutated, aging will be accelerated, oxidative free radicals will damage DNA, and cells will age if they cannot repair the damage.
If telomerase is overactivated at this time, the cells may become immortalized, but this is also a sign of a tumor.
6. Tumor cells can replicate endlessly, but in fact, there is an abnormality in the internal biochemistry of the cell, there is a problem with the environment and DNA replication, the telomerase level is too high, but the DNA telomeres will not become shorter.
The animals used in Ye Xing's experiments are generally simple lives with rapid growth and aging, with a lifespan of only ten days, so the results will be quickly obtained by observing and contrasting.
Sure enough, the length of life depends mainly on the internal biochemical processes of the cell, not all of it is due to genetic DNA.
Let's put it this way, there is not much difference between human DNA, the lifespan should be comparable, but the truth is very different, the real reason is determined by the biochemical processes inside the cell, that is, it depends on the interaction of specific active enzymes.
Ye Xing also used the newly developed electron microscope to observe and compare himself with other people's cells, animal and plant cells, and the cells of white foxes, and he really made a major discovery;
The process of cell division and aging in ordinary people is very fast, but the process of cell division and aging in ordinary people is several times slower, taking the skin as an example, the epidermal cells of ordinary people generally divide once a month. And Ye Xing and White Fox's are only split once a year.
The cell aging process of the cultivator is slower, and the production of free radicals is very small, because of the daily cultivation, most of the free radicals are basically removed every day and the cells are repaired.
Compared with Ye Li and others, inside Ye Xing's cells, after the production of oxidative free radicals, there will be a mechanism that is quickly cleared, which is the fundamental reason why Ye Xing, Qi Ming and others do not look old.
The four of them did take one or more kinds of elixir in the small space of the elixir, so that the cells in the body produced a mechanism to scavenge oxidative free radicals and repair cells, that is, a specific active enzyme was a hundred times higher than others.
Ye Xing also remembered that the ice silkworms and ice bear insects that he found when he went to the North Pole of the ice field ten years ago were the ones that could go without eating or drinking for hundreds of years, and he didn't know what kind of internal mechanism it was.
Immediately took out an ice bear insect from the space ring, carried out a detailed dissection and comparative study of the internal composition of the cell, and after a month, finally had a clear answer;
In addition to the special structure of ice bear cells, the fundamental reason for its long life is that the biochemical processes inside its cells are extremely slow, and they will automatically remove various harmful substances from the cells.
Its cells can maintain the same acid-base level for a long time, and there is a similar active enzyme in the same high amount.
Ye Xing tried to extract this enzyme from the ice bear insect's body, and after half a month of hard work, he really extracted a little bit, stored it in a jade bottle, and mixed it with the ice spirit crystal liquid to keep it active.
It was also tested with the cells of some animals with a very short lifespan, using a very fine syringe under the microscope, taking a microdrop of active enzyme solution, and injecting it into the cell, and sure enough, the cells with a lifespan of only two days were 30 times more.
At the same time, Ye Xing also tested dozens of animal cells, and obviously, the biochemical process of the cells has changed, generally becoming slow, and the lifespan has become longer, and the worst ones are more than ten times.
I also did the test with other people's somatic cells, and sure enough, after injecting the inhibitory active enzyme, the cell activity changed, the damage was quickly repaired, and the level of biochemical activity inside the cell decreased a lot.
Compared to its own cells, the active enzymes extracted from the ice bear are much more effective, which is likely to be a method of cell longevity.
It's just that there are trillions of cells in the human body, and it is impossible to use this injection method, or it is necessary to activate the content and activity of this enzyme in the body, and permanently change the specific active enzymes and acid-base levels inside the cells.
In other words, the problem of longevity at the cellular level is actually completely clear, just how to permanently change the biochemical indicators inside the cell and increase the content of specific active enzymes.