Chapter 310 - Interventional magnetic levitation: a very small artificial heart
"What do you mean?" Luo Ya is not good at Chinese, and I don't know the word Guotai Min'an.
Zhou Qiao told her that it was something that almost every Chinese longed for, although it sounded ordinary, but in fact there was a great wish.
Sui Tsai carefully explained the meaning of "Guotai Min'an".
Luo Yawan'er gave two thumbs up and praised: "As long as it is taken by my father, it's fine!" ”
After a pause, he said, "I also thought of four names, English names, do you want to hear them?" ”
Zhou Qiao clapped his hands and shouted, "Okay! I am responsible for the Chinese name, you are responsible for the English name, the division of labor is clear, very good! ”
"Haha." Luo Ya smiled, heroic and cool, revealing two rows of brilliant teeth.
Although Fang Yuanyuan is also heroic, compared with Luo Ya's aura, there is a world of difference. After all, Fang Yuanyuan is just the youngest daughter, and Luo Ya is in a high position and holds great power, so she is a big man.
"Which four?" Zhou Qiao asked.
Loya: "Klein, Gelman, Sherlock, Lumian." ”
Zhou Qiao suddenly fell into deep thought, how familiar it is, it seems that he has heard it somewhere.
"The sunset on the horizon is so beautiful, come, help me take a picture!" Luo Ya's smile was like a spring breeze, stretching her arms and posing in a beautiful pose.
Zhou Qiao no longer bothered about where he had seen the name, and immediately went to take pictures of Luo Ya.
Anyway, as Luo Ya said, as long as it is the name chosen by the father, then the same, as long as the name is taken by the mother, it is also good!
Generally speaking, the pregnancy period is about 280 days, about 40 weeks.
Children born within 5 weeks of normal delivery within 3 weeks before the expected date of delivery, i.e., after 37 weeks of pregnancy, and within 2 weeks after the expected date of delivery, i.e., within 42 weeks of pregnancy, are all normal births, which are called full-term births.
Luo Ya is only 19 weeks pregnant, more than halfway through, and there is still plenty of time, but Luo Ya has already begun to prepare all kinds of small clothes, small shoes, small scarves, small gloves, small socks, small toys, cartoon bottles, strollers, small cots, ......and even plans to raise a group of cattle and sheep.
As for the various high-end milk powders on the market, you can stock up as much as you want. Anyway, just more, no less. When the time comes, I can't finish eating, and when there are still a few months to come, I will give it to the people in the manor to drink. It won't go to waste.
This is the love of a mother for her child.
On the wine estate, a children's playground covering several acres has been built for the baby to play after birth.
I have to say that the child born with a golden spoon in his mouth is quite happy. Even the territory and family property in a few decades are ready.
One took over the East African Empire, the other took over the French nuclear power plant and the Italian mafia family, the other dominated American politics and perhaps challenged the presidency, and the other took over the commercial companies in the United States.
Zhou Qiao was very ashamed, after he sowed the seeds, he didn't care much, thinking that he would accompany Luo Ya more in the future.
The child was born in the United States, and the mother is a standard American, and he is a naturalized American citizen at birth, and he is eligible to run for president.
In fact, although Luo Ya was born abroad, as soon as she was born, her mother had the foresight to apply for American citizenship for her. She can also run for president of the United States.
……
In addition, with Zhou Qiao here, Sequoia Tree Hospital was suddenly full of confidence. Any patient dared to take it.
Before, when Zhou Qiao was away, some critically ill patients, or those whose conditions were quite difficult, were recommended to be transferred to Houston University Hospital.
Although Zhou Qiao can be connected remotely, it is not good to trouble Zhou Qiao all the time. Moreover, the remote connection is only a guide, and the specific operation has to be done by them, so there is not so much certainty.
And now, Zhou Qiao is here, so it's much more convenient.
……
There is a local uncle in Christ Mills County, 52-year-old Atholl Conway, who was a good hunter a few years ago, and often ventured deep into the mountains and old forests.
However, five years ago, he had a physical problem, and he had symptoms of chest tightness and shortness of breath, which became more and more serious, not to mention hunting, and his daily life was significantly affected.
I once went to another big hospital in Christ Mills, and the doctor diagnosed chronic heart failure and recommended conservative treatment.
So, in the past few years, I have been treated conservatively in that hospital, and basically I have to go to the hospital for half a month or more than a month every year.
However, the condition can only be relieved, not cured, and as a few years pass, it will naturally become more and more serious.
In the past, it only intensified in autumn and winter, but now it is also serious in summer.
Especially these days, it seems that I can't even walk thirty meters. The family suggested going to the hospital again, but Atholl Conway heard that the new Sequoia Tree Hospital was good, the medical conditions were good, and it seemed that the fees were cheaper than similar hospitals.
This is because Luo Ya's original intention of establishing the hospital was for votes, so there is a charitable nature in it.
So, accompanied by his family, Uncle Atholl Conway came to Sequoia Tree Hospital for treatment, and was treated by a senior doctor in the Department of Cardiology.
It turned out that the condition was quite serious, and there was no need for a detailed examination, and after listening to the symptoms, I knew that simply using drugs to adjust heart function would not have much effect, so I was transferred to cardiac surgery.
After a consultation with the cardiology surgeons, they all agreed that a heart transplant and an artificial heart implant were his hope of survival.
However, this kind of difficult surgery has not been carried out by Sequoia Tree Hospital. Fortunately, Dr. Zhou is here.
Dean Joachim Langlei invited Zhou Qiao again.
It's still Lu Xianna, the little black beauty, who picks up and drops off.
Zhou Qiao led the doctors of the Department of Cardiac Surgery and Cardiology of Sequoia Tree Hospital to further improve the examination items for patients and analyze their conditions.
On ultrasound examination, Uncle Atholl Conway's left ventricular ejection fraction (EF) was only 7% at its lowest, which was significantly lower than normal. In general, a normal person's EF is at least greater than 50%.
At the same time, the left heart is enlarged with severe mitral regurgitation, cardiac insufficiency, and the right heart is enlarged with moderate to severe tricuspid regurgitation, pulmonary hypertension, and a trace pericardial effusion.
This is already in the terminal stage of heart failure.
To put it simply, the heart is no longer good, it has completely decayed, to the point where it has to be replaced.
EF represents the heart's ability to pump blood, 7% means that the heart is no longer able to beat, coupled with persistent atrial fibrillation, Uncle Atholl Conway's condition is quite unoptimistic, and timely surgical intervention is required.
For the treatment of patients with advanced heart failure, there are currently only two methods: heart transplantation and implantation of artificial hearts, and Zhou Qiao led the team to evaluate and formulate the most suitable plan for the patient.
In fact, he can analyze the condition and formulate a surgical plan, and now he is leading the team "hand in hand", which is nothing more than to give the cardiac surgery and cardiology department of Sequoia Hospital a chance to experience and grow.
If it was another hospital, there were not tens of thousands of dollars, don't want to invite him to share "a lesson", let alone teach it by hand, but Sequoia Tree Hospital is Luo Ya's team, and Luo Ya has to give birth to four children, so he has to contribute.
Luo Ya spent $5.8 million just to give him a watch.
In the end, Zhou Qiao led the team of doctors to formulate a treatment plan that uses "artificial heart" to cooperate with the original heart.
The patient was 66% positive for HLA class I antibodies, and the cardiopulmonary exercise test result was VO2/kg 8.0ml/min/kg.
What does this mean?
This indicates that the risk of transplant rejection is quite high, and the risk of rejection of HLA class I is generally lower than 10%.
For heart transplantation, plasma exchange is required first, and then surgery is performed within the time after replacement, not to mention the high risk of surgery, and the incidence of postoperative rejection will be very high according to the patient's data.
Therefore, in combination with cardiopulmonary exercise testing, the indications for ventricular assist are clear.
In fact, there are two kinds of artificial hearts, one is to assist the artificial heart, which retains the patient's original heart, and places an auxiliary device next to it to work in conjunction with the original heart, and the auxiliary artificial heart has left ventricular assist, right ventricular assist and double ventricular assist.
The other is to replace the real heart with an artificial mechanical heart, which is a complete artificial heart.
Zhou Qiao plans to choose an LVAD product from Boston Medical.
Boston Medical Company, a subsidiary of Academician Dominory and a leading company in the medical device industry in the United States, is currently working closely with the future medical device company controlled by Zhou Qiao.
Getting the goods from Boston Medical, not only is the quality guaranteed, but the price is very affordable.
Of course, this is not the most important thing.
On top of that, Boston Medical's latest artificial heart is far ahead in all parameters.
Its core component, the blood pump, weighs only 90 grams, with a diameter of 34 mm and a thickness of 26 mm, making it the world's smallest and lightest interventional full magnetic levitation artificial heart.
It is used for surgery, which is less invasive during the operation, has a quick recovery after surgery, and the total weight of the extracorporeal controller and battery worn for a long time after surgery does not exceed 800 grams, allowing patients to travel lightly.
This is not the first generation of VAD products from Boston Medical, but the third.
Since it was Zhou Qiao who asked for the goods, it was sent over quickly.
Zhou Qiao also called, and chatted with Academician Dominory by the way, but he hadn't seen him for a long time, and the old man said that he missed him very much, so he had time to come to Boston again.
In addition, Academician Domitri said that next month, there will be an opportunity for academic exchange, which is to go to the University of Tokyo Hospital in Japan and ask him if he is interested.
Then, Academician Domitrie's research institute is about to test a new drug in Japan, and it needs to go there to do some experiments and collect some data. I also want him to try to lead the team.
"Trials of new drugs in Japan?" Zhou Qiao was taken aback.
He only heard that the United States is conducting new drug experiments in some backward countries such as India, Ukraine, Romania, Tunisia, Lithuania, Brazil, and Argentina, but he did not expect that there are also in Japan.
Actually, there are also in South Korea.
The United States is the father of those countries, and they all have military bases, and this kind of thing is a trivial matter for new drug experiments.
"Teacher, what kind of test is it?" Zhou Qiao asked.
Academician Domitri said: "It is resistant to nuclear radiation. In a radiation emergency, people can be exposed to radiation doses ranging from negligible to life-threatening. As you know, Fukushima discharged a large amount of nuclear-contaminated water into the sea, and there was a mass base for experiments, and many volunteers were willing to cooperate. ”
"The new drug I developed, which I named DOZO 16-1, is a metal ion chelator that can selectively combine with the F-region of the periodic table, lanthanide and actinide metal elements to form a complex and quickly excrete with the excretion."
"In addition, its dosage form is an oral capsule, which is easier to store than intravenous drugs and easier to use and administer in an emergency. Phase I safety and tolerability clinical trials are now being conducted in Fukushima mainly in humans. ”
"Of course, there is still a certain amount of radiation in Fukushima, and if you don't want to, the teacher won't force you. All you need to do is go to Tokyo and participate in an academic exchange. ”
Zhou Qiao thought for a while and said, "I'm willing to go." Give me this chance. As for Murphy and Stephanie, Zhou Qiao decided not to let them go.
First, the iris clinic is busy, and second, Fukushima has radiation, so girls should try not to go.
As for himself, he has quadruplets and sons, and in addition, he has a system that can remove radiation from his body at any time without being contaminated.
Academician Domitri said: "You think about it again, and then you can talk about it." ”
After hanging up the phone, Academician Dominory pondered, if Zhou Qiao was willing to go, he would have to give some compensation, after all, he was taking a risk.
His old man specially paid him, so he naturally wouldn't be stingy.
Academician Dominory considered dividing some of his companies, such as Boston Medical, into some shares, and let Zhou Qiao participate first.
The gossip spread by the previous research institute was not groundless.
In fact, if you only stay in the vicinity of Fukushima for a short period of time and do not enter the nuclear exclusion zone, the impact will not be too great.
The new drug trial is only to recruit volunteers who are contaminated or slightly contaminated in the area, and the experimental site can actually be selected separately.
……
When the small magnetic levitation artificial heart was obtained, the operation began to be prepared in full swing.
This is not a simple operation and can be described as extremely complex.
There were also a lot of people involved.
Medical staff from many departments and fields such as cardiac surgery, ultrasound, anesthesiology, intensive care unit, and cardiopulmonary bypass all came with the purpose of learning.
It's a pretty rare opportunity.
Under the attention and cooperation of so many people, Zhou Qiao led the team members to carry out left ventricular assist system implantation + tricuspid valvuloplasty for the patient.
At the beginning of the operation, Zhou Qiao first underwent a right heart catheterization to reassess the function of the right ventricle, and then performed tricuspid valvulopasia.
As soon as the connoisseur makes a move, he will know if there is one.
Exact positioning, threading the needle, placing the fixed ......
With perfect surgical skills, an ultra-small fully magnetic levitation artificial heart weighing only 90 grams was implanted into the patient's body.
The artificial heart pump head was successfully placed, the blood pump rate was set, and it was successfully operated.
Everyone cheered and jumped for joy, because this hopeful operation was easily successful!
The "artificial heart" gently rotates, assisting the patient's hard-beating heart and keeping him alive together.
This artificial heart is not small, but its pumping capacity is not small, with a displacement of 50 mL and a cardiac output capacity of 10 L/min, which is quite impressive.
After the operation, Uncle Atholl Conway, who was equipped with "turbocharging", was transferred to the intensive care unit, and a series of treatments followed.
Cardiac drug support, diuresis, inhaled nitric oxide to reduce pulmonary artery pressure, etc., can reduce the pre/afterload of his right ventricle, and at the same time, the medical staff will also guide Uncle Atholl Conway to adapt to the artificial heart.
The heart surgery done by Dr. Zhou, a top celebrity, will naturally not have much of a problem, and Uncle Atholl Conway's discharge from the hospital is just around the corner!
(End of chapter)