Chapter 533: Mass production of penicillin
After getting a reserve of 200 tons of gold from Nicholas II, Arthur was still in a very good mood.
Although the gold theoretically belonged to the Russian government, and only if Russia failed to repay the loan within ten years, it did not affect Arthur's mood in the slightest.
After all, the loan has been picked up by an Australasian transport ship and is to be stored in Australasia.
Can Russia really repay $60 million in ten years? This question is worth digging into and has all the possibilities.
However, if we discuss it in the light of Russia's actual situation, there is actually only one answer, that is, it is basically impossible.
Unless the Russian civil war ends immediately, and the Russians stop behaving and enter a decade-long period of recuperation, they may be able to easily repay the $60 million loan in ten years.
But the problem is that neither of these elements is basically possible, and Europe does not want to see the end of the Russian civil war so soon, after all, many countries have not yet eaten meat.
Whose meat is eaten? That's Russia, of course.
Russia has spent more than £2 billion on the war, more than half of which was spent on buying supplies from other countries.
This has also given many European countries a taste of sweetness, and in the period of economic recession, Russia's orders are like a life-saving straw, saving the economies of some European countries, so that the collapse of these countries' economies is at least not so fast.
It is precisely for this reason that the end of the Russian civil war is undesirable for almost all European countries, and under such circumstances, it is impossible to end the Russian civil war on its own except to get the support of all the Russian people.
Did Nicholas II have such prestige? Perhaps before all the events happened, but since Nicholas II ordered the expulsion of the marchers by force, many people have completely lost faith in Nicholas II, and the worship of the Tsar in Russia has gradually decreased.
Russia cannot end the civil war as soon as possible, and there is little hope of repaying the loan within ten years.
In fact, this also means that this gold has almost become Australasia's reserves, and there is a high probability that it will not go out of Australasia.
With this gold, the Royal Bank will be able to print more Australian dollars, creating far more value than 60 million Australian dollars, which is why Arthur is willing to mortgage more Australian dollars.
After all, the Australian dollar was printed by Arthur, and on the premise of having sufficient gold reserves, how many Australian dollars he wanted to print was only a matter of Arthur's words.
After a few happy days, Arthur ushered in the even better news, that is, the aforementioned penicillin had found a way to mass produce.
The importance of penicillin has been mentioned, and the mass production of penicillin is also the most important event for Australasian Pharmaceutical Group at present.
Previously, due to the delay of the flu, the pharmaceutical group focused on the production of masks and disinfectants, as well as the research on the flu, and the mass production of penicillin slowed down.
After the flu really disappeared, the pharmaceutical group did not dare to delay any time, and once again launched the research on the mass production of penicillin, and the results were quickly obtained.
Of course, strictly speaking, the research on the mass production of penicillin took more than five years, and it was not very effective.
From the discovery of penicillin to mass production, this is not a one-step process.
The penicillin found in the laboratory is the result of a coincidence, and how to reproduce this coincidence and effectively achieve the mass production of penicillin with skills has been a key topic for pharmaceutical groups, especially biological laboratories, for a period of time.
Fortunately, both Fleming, who discovered penicillin, and his mentor Wright, have quite good abilities and patience in the field of medicine and biological research.
When it comes to the name penicillin, some people may feel unfamiliar. However, penicillin, also known as penicillin, is a more commonly used antibacterial drug and is a relatively common antibiotic.
It is effective in treating all kinds of wound infections and is a life-saving medicine for soldiers who have suffered various gunshot wounds and traumatic injuries in war.
It is a pity that penicillin was not found in World War I, otherwise it would have saved hundreds of thousands, if not millions, of soldiers and families.
After receiving the news that penicillin could be mass-produced, Arthur did not hesitate and immediately rushed to the pharmaceutical group's biological laboratory outside Sydney.
It was still the same as five years ago, Fleming and Wright, the heads and deputy heads of the biology laboratory, were concentrating on their own research, and Arthur had no intention of bothering.
After about half an hour passed, the afterglow of the two swept to Arthur, and they quickly stood up and saluted respectfully: "Your Majesty!" ”
"No need to be polite, two experts. Heard that mass production of penicillin has been achieved? When will it be able to enter the full-fledged production process? Arthur stepped forward with a smile, signaled that the two of them did not need to be polite, and asked with a smile on his face.
"Your Majesty, the initial mass production method has been realized. According to the current construction progress, the first pharmaceutical plant for mass production of penicillin can be established and officially put into production in two months, opening a precedent for us to mass produce penicillin. Wright replied with a smile.
The mass production of penicillin is the hard work of everyone here, and it is also the pursuit and dream of the biological laboratory for many years.
Since the discovery of penicillin five years ago, Fleming and Wright have conducted a comprehensive study of penicillin, which Arthur has attached great importance to.
Initially, penicillin only dissolved and inhibited staphylococcus, but its true effect on the human body has not been verified.
In order to fully experiment with the new object, Fleming and Wright first studied rats, injected them with lethal doses of streptococcus, and selected a few to be treated with penicillin alone.
The mice eventually treated with penicillin were still alive and healthy, and the other mice all died within a few hours.
The results of this experiment also proved that penicillin has a good therapeutic effect on streptococcus.
In order to increase their conjectures, Fleming and Wright conducted a number of clinical experiments in the following years, not only on mice, but also on monkeys and various animals.
Eventually, after two years of research, Fleming made the bold decision to use penicillin in humans to further explore its therapeutic effects on humans.
In this era, once a person is infected by trauma, the fatality rate is very high, even close to 100%.
This also allowed Fleming to quickly find an infected person who was willing to conduct experiments, and conducted clinical trials on humans with the permission of the government.
The end result is exciting, because penicillin contains penicillane that impairs the synthesis of pathogen cells, causing the bacteria to dissolve and die.
But human and animal cells do not have a cell wall, so penicillin does not affect people and animals, which is the real reason why penicillin can kill germs and does not damage human cells.
After fully testing the effects of penicillin, Fleming and Wright did not hesitate and immediately entered the mass production of penicillin.
To achieve this, with the help of the Australasian government, Fleming collected soil from all over the world and isolated strains from it, increasing the production of penicillin from 2 units per cubic centimeter to about 20 units.
At Arthur's behest, Fleming accidentally found a mold on a melon that could be used to extract penicillin in large quantities, and prepared a corresponding culture from corn flour, increasing the penicillin yield from 20 units per cubic centimeter to about 50 units.
It is also with these results that the mass production of penicillin has become a reality. The biological laboratory immediately began research, and it was not long before the mass production of penicillin was realized.
The pharmaceutical group to which the Biological Laboratory belongs immediately began to build an environment for penicillin production, and as long as the relevant facilities are in place, the pharmaceutical factory in charge of penicillin production, which is named the No. 7 Pharmaceutical Factory, can start mass production of penicillin.
"After the pharmaceutical plant is built, will the penicillin production rate be able to meet our needs?" Arthur asked the most crucial question.
"No problem at all, Your Majesty. Based on our estimated production speed, it will only take one year after the completion of the pharmaceutical plant to meet the needs of Australia. Within five years, the needs of the scale of the First World War could be met. Wright nodded proudly and said confidently.
Once we found a way to produce penicillin in large quantities, it was not difficult to achieve large-scale production.
Hearing Wright say this, Arthur nodded with satisfaction and said with relief: "You have worked hard during this time, you have made significant contributions to the development of Australasia, and the country will not forget your contributions." ”
As he spoke, Arthur motioned for the guards to take out the rewards that had been prepared long ago and distribute them directly to all the researchers and employees in the biology laboratory.
Among them, Fleming and Wright are the most credited, with cheques ranging from $10,000 to hundreds for each other, depending on how long they joined the lab and what they have done in the lab.
But no matter who it is, as long as they get the money, they have a happy smile on their faces.
After all, this is real money, whether it is hundreds of Australian dollars or 10,000 Australian dollars, it is a lot of money for these researchers, and they will naturally be happy to get the money.
For the 10,000 Australian dollars awarded to Fleming and Wright, Arthur was not distressed at all, and even felt that the reward was less.
After all, penicillin can bring Arthur far more than 20,000 Australian dollars, at least 10,000 times, or even millions of times.
You know, even in later generations, penicillin is a very important antibiotic, and the annual production volume is even more huge and scary, and the huge market is enough to create greater profits.
Compared to those profits, $20,000 is simply not worth mentioning. If it weren't for the delicious reward that followed, Arthur would have felt that he was too stingy.
While everyone was still smiling and celebrating, Arthur did not sell anything, and continued: "For the great contribution of Mr. Fleming and Mr. Wright to the study of penicillin, I have decided to confer the title of Baron on Mr. Fleming, the title of Sir on Mr. Wright, and the others according to their merits. Everyone, have a blast! You are the heroes of the country, you are the heroes of the people! ”
After getting the answer he wanted, Arthur did not stay long in the biological laboratory, but only instructed his subordinates to organize a large banquet at the hotel in Sydney to celebrate the discovery of penicillin and the realization of large-scale production.
Of course, before this banquet, Fleming and Wright would also make a request to the researchers to make sure that they did not confide in Australasia in advance to reveal the truth while drunk.
Fortunately, there must have been strict identity restrictions at this banquet, which also ensured that the news of penicillin would not spread abroad.
Although the relevant extraction methods and production methods are destined to be unpreservable, before the leak, it can still generate a lot of income for Australasia, and this money should not be in vain.
After returning to the palace, Arthur officially signed a document granting Fleming, Wright and others knighthoods, which also symbolized that Australasia once again had several more nobles.
In fact, this penicillin research was not limited to the contributions of Fleming and Wright. According to the results of the intelligence investigation and the situation reported by Fleming, because of penicillin, a total of five people were knighted this time, one baron, and four knights.
In the biology laboratory, in addition to Fleming and Wright, the name of another person who received a knight also came into Arthur's sight.
It's a young man, but a true Australasian man.
Howard Walter Flory, born in Adelaide on September 24, 1898, entered the Faculty of Medicine of the National University of Australasia in 1916, and after graduation, he successfully entered the biological laboratory of the pharmaceutical group.
Perhaps because of his same youth (Fleming is 39 years old), Fleming was interested in the boy who had just entered the biology lab and showed his talent, and trained him as a deputy.
Throughout the discovery and research of penicillin, Flory showed extraordinary talent, and his creative thinking provided Fleming with a lot of ideas, which was why he received the title of knight at such a young age.
Of course, the famous Flory is also very famous in the original history.
Coincidentally, this is the person who struggled in the research of penicillin, and it was he who succeeded in increasing the production of penicillin to an exaggerated number.
Because of this, Flory and Fleming were awarded the Nobel Prize in Physiology or Medicine together and were awarded the title of Barony of the British Empire by the famous Queen Elizabeth.
Although the current development and history are different, Flory still struggled with the research of penicillin, and still worked with Fleming to discover and achieve the mass production of penicillin.
For such an Australasian born and raised biological talent, Arthur has only one attitude, and that is to focus on training.
You must know that although there are a lot of talents in Australasia at present, there are not many talents who are truly born and nurtured locally.
Flory is an example of how to better encourage the Australasian government to nurture homegrown talent, and Australasian people to choose their own country's universities and training environments.
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(End of chapter)