432 The right medicine
When it comes to the body's defense mechanism, this blood-brain barrier is undoubtedly the most powerful one.
This is also the main reason why modern medicine is mostly helpless in the face of various brain diseases.
Because of the peculiarities of the human brain, if a lesion occurs here.
Many diseases are not suitable and are treated surgically.
Even if modern medicine is so advanced that brain diseases can be treated surgically, there will be various sequelae.
Therefore, more doctors prefer to use drug treatment when treating brain diseases.
However, the biggest problem facing the use of drug treatment is to face it.
That is how to deliver some special drugs to the patient area.
At present, there are several ways to do it, which are nothing more than intravenous injection, or oral administration.
At the end of the day, it all requires blood to transport drugs to diseased areas of the brain.
However, before these drugs can enter the brain, they must be tested by the body's immune system.
The immune system of this brain is called the blood-brain barrier.
This blood-brain barrier not only kills all kinds of bacteria and viruses that he thinks are harmful.
It also clears all kinds of specific drugs that want to enter the brain......
After all, many special drugs, in fact, to put it bluntly, are special proteins.
The white blood cells in the blood-brain barrier will kill all of these substances that are considered harmful.
As a result, it is difficult for the drug to enter the affected area of the brain.
If you want to achieve efficacy, you need to increase the amount of medicine delivered.
However, once the dosage of the drug is increased, it will increase the burden on the liver and kidneys.
In the end, the disease of the brain was not cured, but other organs were damaged.
Therefore, this is the main reason why many brain diseases are difficult to treat.
Alzheimer's disease, for example, scientists have discovered.
One of the triggers of this disease is that it increases with age.
In the human brain, acetylcholine secretion is greatly reduced.
And if this thing is reduced, it will cause the brain neuron to be insensitive, or even ineffective.
Causes failure of information transmission in the cranial nerves.
For treatment, acetylcholinergase inhibitors are used to increase acetylcholine secretion.
For example, donepezil, rivastigmine, huperzine A, etc.
However, if you want to transport these drugs to the brain disease area, you will face the problem of the blood-brain barrier.
When used in normal doses, most drugs are cleared by the blood-brain barrier defense mechanism.
Only a small percentage can be transported to the patient area.
However, if the amount is increased, it will cause damage to other organs of the human body.
Long-term overdose use will lead to other organ lesions.
So now, doctors can only reduce the dosage and slow down the progression of lesions.
As for completely suppressing the progression of the disease, it is not possible at all.
This is the current state of the treatment for Alzheimer's disease.
And this Fang Tong happened to be because there was an old man in the family who had this disease.
That's why I understand what the blood-brain barrier is.
So at this moment, I was also aroused, so I asked Xu Xin.
Xu Xin listened to his question and smiled secretly in his heart.
You kid, you've got a bite to crack.
This second half is actually the right medicine for you!
"Ah, since Mr. Fang is interested, then I won't hide it."
"The phone call just now came from the person in charge of a project I invested in before."
"Haha, it's finally saved."
"This person's name is Middleton, and he used to be the head of a pharmaceutical company in country M, and the head of the laboratory in the Magic City area."
"At that time, I happened to be doing financial investment work in the magic capital."
"We met at a drinking party, and the more we talked, the more speculative we became, and we became friends."
Later, he had some ideas for scientific research and set up a laboratory in China.
"Specializing in scientific research on the blood-brain barrier, I saw that the project was not bad, so I invested a sum of money in him."
"Later, he went back to country M and set up a laboratory there."
"This research group has been established for almost five years, and now it has finally achieved results."
"My previous investment was not in vain."
As soon as Xu Xin explained this, Mr. Li on the other side also understood why a foreigner called him.
However, when he shifted his gaze to Mr. Fang next to him, he saw Fang Tong's eyes wandering non-stop.
Apparently it is also speculating, measuring.
He suspected that the call had come by a coincidence.
But how did this guy know that his favorite grandmother had Alzheimer's?
And I am also all over the world searching for the treatment of this Alzheimer's disease.
But if you're going to say he doesn't know.
So how could the project he invested in make a breakthrough at this time?
Could it be that this guy still wants to pit himself a second time?
The more Fang Tong thought about it, the more suspicious he felt, but he was looking at Xu Xin.
At least in terms of expression management, what this guy does is not showing.
He didn't see anything wrong.
Think again, if what he says is true.
Oh my boy, that's amazing!
Since his grandmother's Alzheimer's disease, he has also looked up a lot of information.
In China alone, there are 15 million Alzheimer's patients.
Worldwide, there are more than 50 million people suffering from this disease.
And the data is growing steadily every year.
So it's a huge market!
And this disease is not like other diseases, but if anyone in any family has this disease.
Then even if he doesn't want to treat himself, his family will treat him.
His family can't afford to treat him, and the state will pay for him to treat it, because this disease is too grinding......
And now this guy is very short of money......
As soon as he thought of this, Fang Tong's heart began to beat faster.
This opportunity is in front of you, do you want to ......
At this time, he looked up at Xu Xin, this guy picked up the wine glass and took a sip without heart.
"How? You've all asked what you should have asked. ”
"As for the 60 million, it really has nothing to do with me, I was also deceived by that Wang Heng for 30 million."
"If you want, we can also cooperate and find this bastard together."
"Can you send me back now?"
The bald Mr. Li couldn't make up his mind, and turned his head to look at Fang Tong.
Fang Tong turned his heart sideways again.
"Eh, Mr. Xu, are you in a hurry? It's not easy to get out yet. ”
"It's such a beautiful night tonight, why don't we enjoy it and go back?"
"Yo, it's been a long time, you've been talking, are you hungry?"
"Come on, serve ......"
This Fang Tong is really good at enjoying it, and there is a special team of chefs on board.
After a while, they really made a seafood feast full of color and flavor.
"Mr. Xu, it's a bit abrupt to invite you here today, don't take it to heart, come and have a drink."
When the banquet began, Fang Tong toasted Xu Xin.
Xu Xin didn't talk nonsense, he dried it up, and it was a wine and a grudge.
After three rounds of drinking, Fang Tong gave Mr. Li a look.
"Mr. Xu, I just heard you talk about that project, and I am also very interested."
"I don't understand the technology you talked to your friend about, but I can tell that your friend seems to be short of money right now?"
Bald Li asked suddenly.
Xu Xin was stunned: "Huh? This ......"
"Eh, Mr. Xu, we can get together today and we can be regarded as friends."
"If you really need help, why don't you talk about it?"
"Maybe, we can help?"
Fang Tong said at the right time.