Chapter 35 The First Dose of Antibiotics at the End of the Han Dynasty!

Before the Industrial Revolution began, it was not as difficult as usual to rub antibiotics by hand.

Antibiotics such as erythromycin and tetracycline are simply not possible.

Although penicillin can be produced manually, the yield of penicillium is pitifully small before modern industrial radiation selection.

Not to mention that the production process is cumbersome and abnormal, even if it is made, there are still a lot of impurities that are harmful to the human body that cannot be removed.

It's not so much an antidote as a poison.

Under such medical conditions in the late Han Dynasty, it could only be taken orally, if you tried to inject it with a needle...... That's looking for death.

I had a chance to survive the plague, but I died on the spot as soon as I was injected.

Comparatively speaking, there is an antibiotic that is very suitable for manual extraction, and the yield is also relatively much higher, and the content of harmful substances is also very low.

In addition, the extraction process is much simpler, even in ancient times when there was no industrialization, it can still be extracted manually.

Moreover, its antibacterial ability is very good, and the types of antibacterial bacteria are also wider.

Penicillin is only effective against bacteria and not against fungi, but this antibiotic is one of the few antibiotics that can work against both bacteria and fungi.

The most important thing is that it is also suitable for oral administration!

The name of this antibiotic is allicin.

As the name suggests, it is an antibiotic extracted from garlic.

After entering the industrial age, the main users of allicin were farms that raised livestock.

But.

Even veterinary antibiotics were still absolute miracle drugs in ancient times.

After all, what can save lives, where does it matter if you are a beast or not?

The only problem is......

Was there any garlic in the late Han Dynasty?

Many crops in ancient times were imported products, and there was no local area.

For example, peppers, tomatoes, potatoes, sweet potatoes, etc.

Including garlic, in fact, it is also an exotic variety.

Garlic originated in Central Asia and the Mediterranean region.

Luckily.

At the end of the Han Dynasty, there was garlic.

As early as the Western Han Dynasty, when Zhang Qian went to the Western Regions, he was introduced.

Historically known as "garlic".

Later, it was popularized, and by the end of the Han Dynasty, it was already one of the common crops.

……

Open your eyes and go back to the end of the Han Dynasty.

Lu Yu immediately took action.

After you have everything you need to prepare.

The first experiment began.

Start by mashing the garlic so that it becomes minced garlic.

At this time, the alliin and alliinase in the garlic collide to produce a decomposition reaction.

In this way, allicin is formed.

Leave it for another half an hour.

To make the reaction sufficient, the concentration of allicin at this time is the highest.

In principle, it is not too simple to obtain allicin, as long as it is made into garlic puree, it can be automatically generated.

Allicin has a strong inhibitory effect on most cocci and bacilli, and even some molds, viruses, human parasites and other microorganisms.

Whether it is taken orally or externally, it has a very good antibacterial effect.

Merely.

It's not enough to turn garlic into an antibiotic for all.

Because allicin will be further decomposed at room temperature, and the content is too low.

Therefore, if you want to cure your illness by eating garlic, it is really a drop in the bucket.

Looking at the garlic that had fully reacted and smelling the pungent smell, Lu Yu said softly: "It's now." ”

He picked up a jug of high-purity alcohol.

The high concentration of alcohol is also easy to make, and the liquor is dried with quicklime and then distilled.

In this era, there was distillation technology, but there was no distilled spirit.

Through distillation, Lu Yu obtained a high concentration of alcohol, then soaked the garlic paste with alcohol for half an hour, and finally extracted the allicin solution by distillation.

This step can actually be replaced by water and extracted by steam distillation.

After all, garlic is not valuable, but wine is different, especially high-concentration alcohol, which requires a lot of wine to extract, which cannot be popularized and applied at all.

The reason why I use high concentration alcohol at this moment is just to extract the highest concentration of allicin solution.

Let's see how effective this allicin solution is in the treatment of the plague.

If it really works.

After that, just use water instead of distillation to extract, even if the content is a little lower, it doesn't hurt, as long as it has an effect!

Extracted with distillation.

Soon.

Lu Yu obtained some garlic solution with a golden color.

This is relatively rich in allicin.

"The first dose of antibiotics at the end of the Han Dynasty was taken out by me."

Lu Yu looked at the translucent golden liquid, his eyes full of anticipation.

Although extracting this allicin is relatively simple, it has many disadvantages.

One is the pungent taste, and the other is perishable.

After making it, it must be taken as soon as possible, and it is not suitable for long-term transportation, otherwise the effect will be greatly reduced.

But no matter how many shortcomings it has, as long as it can be effective, then everything is worth it!

Lu Yu called Kong Yue.

"Big brother!" As soon as Kong Yue entered the house, he smelled the pungent smell of garlic, and it was inevitable that he felt a little strange in his heart.

"Do our people have typhoid fever and the plague?" Lu Yu asked directly.

"Not really." Kong Yue shook his head: "We all listen to the words of the eldest brother, wear silk cloth to cover our mouth and nose, the silk cloth is scalded and washed every day, everyone drinks hot water, lime is sprinkled outside the house, and we are careful when entering and exiting, so no one has been infected with the plague until now!" ”

"These methods of the eldest brother must still be effective, but unfortunately many people in the sect don't take this seriously, they still drink raw water, and the silk cloth is not washed, which is really harmful to others and themselves!"

Hearing this, Lu Yu shook his head and said, "The habit of drinking raw water can't be changed in a day or two, and there's no way to make a fire to drink water anytime and anywhere, and there is not enough firewood." ”

"I proposed these methods to prevent problems before they happen, but I also knew that if I wanted to prevent them completely, it was impossible, as long as there was some effect, it would be very good."

"By the way, find someone to take me to the camp for typhoid patients."

"Yes...... Yes? Kong Yue subconsciously should be, but before he opened his mouth, he noticed that something was wrong, and hurriedly raised his head and said in astonishment: "Big brother, are you going to the typhoid patients?" There are all typhoid plague patients over there, if the eldest brother is infected with wind cold, what should it be? ”

Taiping Dao gathers patients infected with typhoid fever and plague to prevent the spread of the source of infection as much as possible.

Because the talisman water can be used to cure the plague, these typhoid plague patients did not resist, but cooperated very much, otherwise they would be 'unbelievers', and they could only wait for death.

Those who have not been infected with the typhoid plague will never dare to approach that side, unless it is some people who have drunk the water and survived the typhoid plague, they dare to enter and exit at will, in the eyes of these people, they have been blessed by the great sages and good teachers, and they are not afraid of this little plague at all!

Lu Yu's request caught Kong Yue by surprise, and he couldn't understand why the eldest brother wanted to go to such a dangerous place.

"I've got a medicine that may have an effect on the typhoid plague." Lu Yu thought for a while and said, "So I want to give it a try." ”

"Then, hand it over to someone else!" Kong Yue was stunned for a moment, and then shook his head, resolutely opposing Lu Yu to go on an adventure.

At this moment, someone from outside the house came to report.

"Deacon Tang sent someone to deliver the letter!"

"Let him come." Lu Yu nodded.

Soon, a tall young man walked in.

This is Tang Shigui's personal guard, Lu Yu has some impression of him, his name is Fan Yun.

"Deacon Lu!" Fan Yun saluted seriously.

"Brother Tang asked you to come over, what is the matter?" Lu Yu asked.

"Childe has been busy with business these days and accidentally contracted typhoid fever...... Fan Yun said in a somewhat depressed tone: "So, Childe said, the business with you, I'm afraid it will be delayed a little, this is Childe's letter......"

He was originally a slave of the Tang family, and after becoming Tang Shigui's personal guard, Tang Shigui was relieved of his status as a domestic slave, because he was grateful, he was loyal to Tang Shigui, and his mood at the moment was naturally very heavy.

Lu Yu frowned, he really didn't expect that Tang Shigui was infected with typhoid plague!

"Take me there!" Lu Yu took the letter, took a brief look, and then raised his head and said.

Fan Yun was stunned for a moment, but still nodded: "Yes!" ”