Knowing that four firefighters were unfortunately poisoned while performing their duties, Liu Tangchun immediately rushed to the rescue room to deploy work.

Unlike other types of disease, acute organophosphate inhalation poisoning can cause very severe respiratory and nerve damage. When organophosphorus passes through the lungs and enters the bloodstream, it produces an inhibitory effect on acetylcholinesterase in the human body. The main role of acetylcholinesterase is to degrade acetylcholine.

Acetylcholine is a special substance that acts mainly in several special nervous systems of the human body. The sweat gland secretory nerves that control sweat secretion, all the parasympathetic nerves, the preganglionic fibers of the sympathetic nerves, etc., are transmitted through acetylcholine. Acetylcholinesterase, on the other hand, works by terminating these transmissions at the right time.

After the degradation function of acetylcholinesterase is prevented by the interference of organophosphorus, excess acetylcholine floods the nerves, and the secretion concentration continues to increase. Eventually, it will trigger generalized choline nerve excitation, and there is only one result after excessive excitation - failure.

The main causes of death in organophosphate poisoning are respiratory failure and coma due to nervous overexcitation. To rescue a person from poisoning, it is necessary to first get rid of the toxic environment, and then immediately use anticholinergics to help the body hydrolyze too much acetylcholine in the nervous system.

The drug of choice for clinical rescue of organophosphate poisoning is atropine.

Atropine is usually used in resuscitation to relieve visceral colic, including gastrointestinal cramps, as well as sinus bradyarrhythmia and atrioventricular obstruction. Atropine extracted from belladonna or mandala blocks the choline nerve's response to acetylcholine, thereby stopping the choline nerve's overexcitation.

And the reason why Liu Tangchun made a special trip to the rescue room to arrange the work was because of a somewhat speechless reason.

At present, the dosage of atropine injection produced by pharmaceutical factories is too small, and the common specification of atropine injection is 0.5mg/1ml. In order to achieve the blocking effect, a patient needs at least 400mg of atropine per hour, that is, a minimum of 800 bottles of atropine injection is enough.

High-dose atropine injections have not been produced for many years. The clinical use of atropine is mainly based on its antispasmodic effect. Large doses of atropine injections do not seem to be necessary – after all, there are simply too few cases of organophosphate poisoning.

"All the nurses who can leave their posts, all the resident doctors who don't have patients at hand, all gather at the nurses' desk!" Director Liu shouted at the top of his voice in the emergency room, "Come and break the ampoule!"

The door of the rescue room was pushed open, and a blue flat trolley was pushed in by the pharmacy staff, "Director Liu, the atropine injection you want, there are five boxes here, a total of 2,500 pieces." ”

Sun Lien was taken aback by this number.

"It's not enough, hurry up and move again. Urging the pharmacy to continue to deliver medicine, Director Liu asked the nurse to give a 100-milliliter syringe to each of the doctors present, "You all know how to open ampoules, so I won't talk nonsense." Hurry up, the helicopter is expected to arrive on the tarmac in six minutes, and before then, at least four people will have to come up with atropine!"

The normally chaotic and orderly organizational structure in the emergency room of the Fourth Central Hospital began to play a role. The senior nurses suddenly turned into sheepdogs and began to drive the residents in white coats to cooperate with each other. Each nurse was in charge of three residents at the same time, and they quickly knocked out the head of the ampoule in their hands with scissors. The ampoules that were cracked open in groups of five were quickly stuffed into the hands of the residents. The injection was carefully drawn into the syringe, and then the cracked ampoule was thrown on the spot in the empty box, followed by the opening and inhalation of the second and third groups.

Sun Lien and Xu Yourong did not join the team, the neurosurgeon's hands needed to be protected, and the rough work of breaking ampoules was not suitable for Xu Yourong, and Sun Lien was called up by Director Liu.

"You go to the pharmacy immediately and find Han Wenping, the director of the pharmacy department. Liu Tangchun called Sun Lien, "Tell him that I still need at least more than 10,000 atropines here." I don't care if he steals or robs, or simply goes to the pharmaceutical factory to move the warehouse, within an hour, I have to see the medicine, do you understand?!"

Sun Lien was about to go out, but suddenly heard Liu Tangchun shouting behind him, "Tell Han Wenping that this is Dean Song's order!"

Dean Song Wen had indeed given the order. She received a call directly from the municipal party committee two minutes ago. Long Xinsheng, secretary general of the municipal party committee, made a direct request on the other end of the phone, "At all costs, do your best to cure these four heroic firefighters." ”

The call ended quickly, and when it was over, Secretary General Long deliberately emphasized again, "We must not let heroes shed blood and tears, and we must use the best measures and the most advanced means!"

Now the most stressful person in the whole hospital is President Song Wen, who received the call. When she answered the phone, Liu Tangchun happened to be in the dean's office to report on the progress of the emergency response mechanism. In this way, Deputy Director Liu was arrested by his own director and dean.

"Director Han, I'm Sun Lien from the emergency department. Sun Lien pushed open the door of the pharmacy, and a group of pharmacists were carrying boxes in the storage warehouse. In order to make it easier to do their work, these doctors, who were not very strong, even took off their shirts and walked back and forth from the shelves shirtless.

After asking several people in a row, Sun Lien found Han Wenping, the director of the pharmacy department who was shirtless and moving boxes, in the deepest part of the pharmacy.

"Director Liu said that the current dose of atropine is still not enough, and more than 10,000 atropine must be gathered within two hours!" In order to better preserve the medicinal materials in the reserve warehouse, a low temperature of about eight degrees has always been maintained. Director Han is a bald head, and his bare head is hot in the warehouse. When people reach middle age, it is inevitable to have a beer belly, but Director Han's upper body muscle lines are still quite conspicuous - he looks like he can beat at least five Sun Lien.

"Isn't my mother looking for medicine?" Director Han wiped the sweat from his head and scolded his mother, "Four organophosphate poisoning! Last year, I said that there was a shortage of atropine, but no one believed it!"

Sun Lien didn't dare to get involved in the war of words of these directors, he just faithfully performed the duty of a messenger, "Director Liu said, whether you steal or rob, or simply go to move the warehouse of the pharmaceutical factory, atropine must be delivered." After a slight pause, Sun Lien continued, "Director Liu said, this is also what Dean Song meant. ”