Chapter 188: It's Not the Same Thing (Supplement September 5 1/1 Update)

If the myocardial ischemia infarcts, the myocardial cells are completely dead. Cardiomyocytes and nerve cells in adults are among the most regenerative cells. Therefore, myocardial infarction due to myocardial ischemia and cranial nerve death due to stroke, therefore, myocardial infarction and cerebral infarction can cause almost irreversible damage. Clinically, the treatment of these two diseases is also the most fast-seeking - the faster the reversal of myocardial infarction and cerebral infarction, the easier it is to control the extent of the damage. The smaller the extent of the injury, the easier it is for the patient to recover later and the fewer sequelae.

Because there is no clinical ability to reverse the damage in these two areas, doctors will actively intervene once they determine that these two areas may be at risk.

With the development of modern medicine, the fatality rate of acute pancreatitis has been so low that it can be taken less seriously. However, cerebral infarction and myocardial infarction are still the number one and second leading causes of death among Chinese residents.

If the problem of regeneration of heart muscle cells and nerve cells can be solved, many incurable diseases may be solved. Perhaps one day, those patients who are suffering from diseases will be able to regain a healthy heart and a normal brain with the help of a dose of medicine.

But this kind of thing, doctors can't do it now. Therefore, everything possible must be done to prevent a heart attack or cerebral infarction.

Hypokalemia is a dangerous symptom that can cause various muscle paralysis and even more serious arrhythmias and cardiac arrest. However, hypokalemia due to plasmapheresis is completely preventable – as long as the serum potassium is monitored intensively and potassium replacement is always prepared.

The treatment plan is carried out by a specialist, and Sun Lien sits in his office, looking through the literature. He was still a little uneasy in his heartβ€”Wang Ge's blood lipids had risen too fast, too much. In the past, although I have heard that some patients will have symptoms of elevated blood lipids after receiving hormone shocks, Sun Lien has not encountered this situation. What he couldn't understand even more was why it was rising so fast.

Hormone shocks are not without risk. Before taking hormone pulse therapy, families will need to sign a notification form that outlines the possible risks of various hormone shocks.

However, the work of consulting relevant literature is not very smooth, and after the recent revision of CNKI, Sun Lien often encounters the problem that good literature cannot be downloaded. THE INFORMATION ON WANFANG IS NOT COMPLETE, AND THE PAPERS ON PUBMED DO HAVE SOME RELATED CONTENT, BUT THEY ARE ALL PAID ARTICLES - A JAPANESE PAPER FROM AROUND 2000, PRICED AT $39.96 ON THE JOURNAL'S WEBSITE.

While doctors are more than willing to exchange experiences with each other, it is clear that the capitalist journal publishers do not think so. Twenty years ago, the paper cost close to 300 yuan to download, and the paper itself was only a four-page PDF and six figures. It's not a matter of robbing anymore...... This is simply a monopoly of knowledge. Compared with this kind of fee, three or five yuan for a paper on CNKI is simply cute, like a white rabbit, harmless to humans and animals.

Although the heart is full of dissatisfaction, the patient's health is still important. Sun Lien gritted his teeth and stomped his feet, and successfully spent the first amount of money given to foreign periodicals and magazines in his life. Then I downloaded this Japanese paper from 2000.

This is a case study of hyperlipidemia in patients after kidney transplantation. The authors documented 129 patients with hyperlipidemia after kidney transplantation. In addition, after the patients treated with methylprednisolone were switched to tacrolimus, the original hyperlipidemia was significantly improved.

After reading the paper, Sun Lien was a little disappointed. The content of this paper is very rigorous, and the arguments are very detailed. However, I don't know if it's because the Japanese have a preference for low-fat diets, and the triglycerides of the most severe hyperlipidemia patients recorded in the paper are only 282mg/dl, which translates to about 31.83mmol/L. This is still some distance from Wang Ge's blood lipid level of 50mmol/L.

Although the triglyceride level of Japanese patients did not rise as quickly as Wang Ge, the probability of hyperlipidemia was still high when receiving 500mg/d methylprednisolone. Of the 947 patients documented in the paper, 129 had varying degrees of elevated triglycerides. With a high blood lipidemia incidence of almost 13 percent, it doesn't seem like a problem.

"What are you doing?" Yuan Ping'an wandered to Sun Lien's side, stretched his neck to look at the computer screen, and then asked with some surprise, "Check the literature?"

"I'm a little worried about Wang Ge's blood lipid levels. Sun Lien sighed, "It's only the second day of the hormone shock, and his triglycerides will be 50......"

"This ...... Is there anything to worry about?" Yuan Ping'an pondered for a while, and then asked with some puzzlement, "After receiving hormone pulse therapy, it is a normal side effect for blood lipids to rise, right?"

"Yes. Sun Lien nodded, "But from normal, it suddenly soared to 50, and this level is too high." I'm worried if there are other factors that are causing such high triglyceride levels, so I'm looking up the literature. ”

Yuan Ping'an frowned and thought for a while, then continued to shake his head, "I really don't think there is anything special about this situation-I have seen a more exaggerated increase in the Association before. It's all normal after receiving hormone pulse therapy......" He shook his head and continued, "Forget it, it doesn't matter what I think, did you find anything about it?"

"Nope. Sun Lien sighed, "I've never seen such a high rise, so I checked it out...... It cost more than 200 yuan. ”

"STILL NEED TO SPEND MONEY?" YUAN PING'AN WAS EVEN MORE SHOCKED, "WHAT LITERATURE DO YOU USE?"

"IT'S PUBMED. Sun Lien deliberately opened his own payment interface and record, "The full text needs to be downloaded and paid." ”

Yuan Ping'an glanced at Sun Lien like a monster, "Are you really giving?" After a pause for a few seconds, he suddenly laughed, "That's right, you shouldn't have done much scientific research before, and you haven't seen many treasures." Speaking of this, Yuan Ping'an unceremoniously squeezed Sun Lien away from the front of the computer, and then began to type a web address on the keyboard with both hands, "Come, I'll show you a baby." ”

This feeling...... It's kind of like the old days in a college dorm.

"AFTER YOU SEARCH FOR THE LITERATURE YOU NEED FROM PUBMED, WRITE DOWN THIS PMID NUMBER, OR THIS DOI NUMBER. Yuan Ping'an handed over Sun Lien how to bypass the capitalist knowledge barrier, "and then enter it on this website......

"What are you doing?" Xu Yourong didn't know when he arrived in the office, but the atmosphere of the "men's club" on Sun Lien's desk was so strong that Xu Yourong himself was reluctant to approach, "The content of the network access in our hospital is stared at by the Information Department, don't say I didn't remind you, if you look back and criticize it, everyone's face is not good-looking." ”

"I'm sure you've used this site. Yuan Ping'an said without replying, "Isn't it just to look at P and HUB, and the information department can still eat me?"

Xu Yourong was silent for a while, "I remember the ...... that this website can't be accessed in China."

YUAN PING'AN RAISED HIS HEAD SUDDENLY, HE GLANCED AT XU YOURONG, WHO HAD A NOT VERY NORMAL EXPRESSION, AND THEN COUGHED, "I'M TALKING ABOUT PUBMED AND SCI-HUB." ”

Xu Yourong left the office without saying a word, and Yuan Ping'an continued to look down at the screen, as if nothing had happened.

Sun Lien lowered his head and wrote down the two websites that Yuan Ping'an said, and after a while, he asked, "What did you two just say...... It's not the same thing, is it?"