Sun Lien and Tang Min's mother talked for a long time, and Tang Min's mother was most concerned about only one question - where to sample the genes.

"The child already has two big scars on his head. At the mention of this, Tang Min's mother was a little emotional. The impact of a brain biopsy on a person is enormous, and the uncontrollable nature of the huge risks in the biopsy process makes every biopsy a big gamble. Tang Min's parents are almost gambling on their child's remaining memories, mobility and other valuable abilities to make a definitive diagnosis. "After the last biopsy, her right foot didn't move very flexibly......"

"If you want to take a sample, you should be able to draw blood. And the amount is not too much, about five milliliters. Sun Lien already has some preliminary understanding of gene sequencing, although it is still very superficial, but it is enough to answer questions for Tang Min's mother. "However, sampling does not necessarily lead to valuable leads...... I'll have to make this clear to you. ”

It is a very inhumane thing to give a desperate mother a false consolation that will soon be punctured. At the same time, as a doctor, this is also a very unwise and unprofessional behavior. Although it can be brutal, clearly informing the family in advance of the risks and uncontrollable factors can also give the family a more objective idea of what is about to happen.

"Genetic testing, on the one hand, is limited by the imperfection of genetic testing methods, and there may be some wrong results. If we find something valuable, we may need to take another sample for a second comparison. "On the other hand, if genetic testing doesn't detect a problem...... Then we may have to continue to observe Tang Min's next symptom changes. This process can take a long time. ”

"How sure are you that you can...... Can you find out what kind of illness she has?" Tang Min's mother asked rhetorically, "We have been to many hospitals, and the experts and scholars there were full of confidence at first, but later they all said that there was no way to ......."

"To put it bluntly, diagnosis is a process of trial and error. Sun Lien took out a pack of tissues from his pocket and handed it to Tang Min's mother, who was crying silently in front of him, "Although it sounds cruel...... But it's true. We're currently looking at two things, one is a genetic disorder – your brother's sudden vision loss is a clue. On the other hand, we have invited experts from the United States to study and sort out the cases, and it is estimated that we will soon be able to get a preliminary opinion. But if you ask me how sure I ......" Sun Lien paused, then shook his head and said, ""

Sun Lien couldn't say which situation was more cruel - a little girl who had a brain tumor at the age of seven, or a little girl who was diagnosed with a genetic disease at the age of seven. But complaining or self-pity is not a constructive attitude. The doctor's main job is to identify the problem and improve or simply solve the problem.

"Then ...... Please. After a long silence, Tang Min's mother bowed to Sun Lien. "We're running out of steam, and in any case, the Fourth Central Hospital will be the last hospital we will see. She raised her head and said to Sun Lien, "You are the child's last hope." ”

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When Sun Lien returned to the office, it was already six o'clock in the evening. Hu Jia just sent a WeChat message to ask Sun Lien what time he can get off work today, but Sun Lien can only describe in general terms that he has a very troublesome patient at hand, and he is still waiting for Xu Yourong and Rachel's diagnosis opinions on tumors.

"Sister Xu is back?" Hu Jia didn't care at all that Sun Lien might be home late, her attention was all focused on Xu Yourong's return to China, "And you came back with Rachel?"

Before Sun Lien could ask his girlfriend, Xu Yourong came back with Rachel and was hung up. He smiled wryly twice, and then decided not to call back and ask what was going on—instead of that, he thought he might as well go find Rachel and ask how far it had got.

Xu Yourong and Rachel occupy a small conference room with a window. Since the two of them entered the room, they have hung a sign outside the door that reads "In use, do not disturb". If it weren't for the fact that the figures of the two of them were across the table on the frosted glass outside the conference room, Sun Lien really didn't dare to knock on the door directly.

"Yo, Dr. Sun. After knocking on the door, it was the short-haired Rachel who came to open the door, and she greeted Sun Lien, "Come over to supervise the work?"

"Not the overseer. Sun Lien entered the conference room under the leadership of Rachel, he nodded to Xu Yourong, and then found an empty stool and sat down, "I have already contacted the sequencing company, and I will draw blood for Tang Min and send samples for testing later." ”

"You've figured out what disease she has?" Rachel's eyes lit up, then a confused and thoughtful expression, "Are you sure it's not a tumor?"

"I didn't know, and I'm not sure if it was a tumor. Sun Lien shook his head, "It's just that now there are just two directions of suspicion, working in two directions at the same time." He looked at Xu Yourong again, "How's your translation going?"

"I've basically finished reading it. Xu Yourong didn't look up, she was still looking at the case in front of her, and from time to time she wrote something on it with a pen. After writing the last few strokes, Xu Yourong raised his head and looked at Sun Lien, "I don't think it's a genetic disease." ”

"Do you think it's a tumor?" Xu Yourong has been working in neurosurgery for so many years, and she has probably seen more brain tumor patients than Sun Lien has seen. Sun Lien also attaches great importance to Xu Yourong's opinion, "What is the reason?"

"There are multiple masses, and most of the lesions are located around the major cerebral vessels and lateral ventricles. Xu Yourong explained, "Although the two biopsies did not detect any valuable lesions, we could see that there was a mild proliferation of glial cells, although it has not yet reached the point of diagnosing a tumor, but it does look like a tumor." ”

"If it's a tumor, it's more likely to be a diffuse glioma. Rachel added, "Multiple lobes are involved, and the disease is progressively worsening, which is very consistent with diffuse glioma." ”

"The question now is how to tell if a biopsy fails to detect cancer cells or not. Xu Yourong looked a little embarrassed, "If it is really a tumor, it is very likely that she is still in a relatively early stage." Starting treatment early has a very positive impact on her prognosis. ”