A life is more worthy of Shen Xi to be serious than a meal and a girlfriend, which Sun Lien is very confident in. But a joke is always finished, and a joke that is taken back in the middle of the story is no different from a mockery.

Sun Lien finished the work at hand, and then carefully locked the screen with the password that came with the old thing, and he was ready to go to the ward to see Tang Min's situation.

The little girl is now lying in the hospital room, slowly eating dinner with the help of her mother. Sun Lien couldn't see the carefree nature of children of this age from her face, and Tang Min's face was full of depression and sadness.

Sun Lien motioned for Tang Min's mother to continue feeding her, while he quietly sat on the sofa farthest away from Tang Min in the ward. The brand-new sofa is very soft and comfortable, and it also makes it easy for Sun Lien to observe Tang Min's movements and expressions.

"Mom......" After Tang Min ate a few more bites of food, he suddenly asked cautiously, "I...... Am I wrong?"

What he said was clueless, and Sun Lien and Tang Min's mothers were stunned.

"I ...... I shouldn't have secretly played with your lipstick......" Tang Min suddenly began to burst into tears, and large tears poured out of her godless eyes. "It must be because I played with your lipstick that I couldn't see ......"

The children's feelings are mostly straightforward and strong and simple. Somehow, this sentence was like a heavy hammer, smashing into Sun Lien's heart.

Tang Min's mother opened her mouth, tears quickly welling up on her face. But she bit the back of her hand fiercely, and comforted the child in a very normal and gentle tone, "Do you think Mom doesn't know? Mom already knew." ”

She slowly hugged her child, then gently stroked her head with her tooth mark hand, "You haven't done anything wrong, you're just sick, and there are a lot of amazing doctors who are already treating you." Min Min be good, be strong, you will be fine soon......"

Sun Lien could see Tang Min's mother's tears running down her face, and then slowly wet the clothes on the child's shoulders.

·

·

·

After a long while, Sun Lien saw Tang Min's mother with red eyes outside the ward.

"Excuse me...... Makes you smile. Tang Min's mother smiled embarrassedly with a thick nasal voice, "The child has been sick for so long...... She was also a little panicked. ”

"It's human nature. Sun Lien nodded kindly, he had not fully recovered from the shock just now. But he fully understood and admired the mother in front of him. He was silent for a moment and then said, "I'm here mainly because I want to discuss something with you and the child's father......"

"Her dad went shopping and should be back soon. Tang Min's mother's expression suddenly became a little nervous, "Yes...... Is it a matter of hospitalization?"

Sun Lien quickly shook his head. Thinking about it with my ass, I also know that Tang Min's illness is like gluttony that continues to eat away at the family's financial health. Traveling to many hospitals across the country continuously, the cost of going out to see a doctor all year round is definitely not affordable for ordinary families.

Looking at the slightly loose and old-style clothes on Tang Min's mother now, this is probably the winter clothes of several years ago.

"At the moment, your hospitalization and examination fees are free of charge. Sun Lien first took out the things that had been determined, so that Tang Min's mother should not be so nervous. "Professor Zhang should have told you that our diagnostic center has its own set of ...... Billing process. "If you and the child's father are willing to give us permission to use and study all of the child's diagnoses, then the hospitalization and examination fees are free of charge." ”

"Yes, yes, yes...... That's what Dr. Chang said. Tang Min's mother nodded, and she seemed to be a lot more relaxed.

"You don't have to worry about the cost. I am coming to you now mainly to discuss with you about the examination of your child. Sun Lien then continued to get down to business, "The situation is like this, I plan to take a sample of the child for a full sequence of genes test, and it will take about two weeks from sampling to the results. I think...... If you can do it earlier, then try to rush to the front. In this way, if we really find out what the problem is, we can also start to intervene in a relatively short period of time - she has been sick for a long time, and if we can intervene earlier, we may have a chance to recover some vision. ”

Sun Lien put it more ...... Guard. But he also left a chance for the poor mother and her child in front of him.

The vast majority of genetically induced diseases are incurable. There are only four adenovirus vector-based gene therapy drugs available for the treatment of spinal muscular atrophy and Leber congenital amaurosis type 2 and early-onset retinitis pigmentosa.

The therapeutic principle of these two adenovirus vector-based drugs is to use adenoviruses containing edited gene fragments to add the correct gene sequence to human cells to treat diseases caused by congenital factors.

But because the incidence of these three diseases is so low, and the cost of gene-editing adenovirus is too high, pharmaceutical companies have set a jaw-dropping price for both drugs. The SPINRAZA treatment for spinal muscular atrophy costs $750,000 for the first year and $375,000 per year for the second year and for a minimum of five years. Zolgensma, which also treats spinal muscular atrophy, is quoted as high as $2.12 million, but it is expected that no other treatment will be required for the rest of his life after one injection. Oral Evrysdi, on the other hand, costs $340,000 per year. Luxturna, which treats leber2 and early-onset retinitis pigmentosa, is priced at $850,000, but for now, the results will gradually decline over four years, and patients are likely to need to be treated again ten years after their first treatment to maintain results.

All in all, gene therapy is extremely difficult, and the efficacy is difficult to achieve the point of "one treatment, a lifetime cure". Most of them are ridiculously expensive, and their efficacy is inconsistent.

And Tang Min's symptoms are completely inconsistent with Leber2, which means that even if she is determined to have a genetic disease, none of the drugs can be used directly on her - even if the drug is frighteningly expensive.

However, this does not mean that Tang Min is completely hopeless.

Gene editing technology is maturing rapidly, and adenovirus-based gene editing treatment options are theoretically no more difficult than others. If it can be determined that Tang Min is suffering from a new genetic disease, then in a relatively short period of time, more doctors may notice that the symptoms of the patients they see are the same or similar to Tang Min's.

The greater the number of patients identified, the greater the willingness of pharmaceutical companies to develop drugs for the disease. And as they advance their research, there may be cures, or at least slowing the deterioration, of treatments.

That's hope.