The official name of the small blue pill is Sildenafil, which translates to Chinese called sildenafil, and the molecular formula of the white crystalline powder is C22H30N6O4S, which was originally a drug for the treatment of cardiovascular diseases, and it does not want to promote the movement of the blood, but contrary to the researcher's wishes, it is to go to the cavernous blood vessels, so its commercial name Viagra has become the "Viagra" that has been passed on by the master.

Not to mention that Zheng Jianguo doesn't remember the synthesis process at all, he doesn't remember the materials used alone, such as n-propylpyrazole, ethyl carboxylate and dimethyl sulfate, of course, these things are not very important to him, because these are all processes, even after refining sildenafil white crystalline powder, the purpose of sending it into the human body is to get the result: NO!

Together, these two letters do not mean opposition in English words, nor are they ordinal numbers in rankings, but nitric oxide, which represents the chemical formula.

As a nitrogen oxide, this thing is a toxic substance in the normal state, due to its own free radicals, it will also react after encountering oxygen, and the result of the reaction is NO2, nitrogen dioxide.

And if you encounter water at this time, then nitric acid will be formed, and at this point, congratulations on synthesizing strong acid!

According to Zheng Jianguo's memory, at this time, doctors used nitroglycerin to treat ischemic heart disease for this reason, and he also knew that nitric oxide can treat ischemic heart disease because this thing can play a role in dilating blood vessels.

Since blood vessels can be dilated, the blood vessels leading to the corpora cavernosa are also blood vessels, so the original single-plank bridge instantly expanded into an airstrip-

In fact, Zheng Jianguo also knows that this thing can promote blood circulation in the brain, regulate the secretion of insulin in the human body, reduce blood viscosity, smooth muscle relaxation, immune response, apoptosis and synaptic information transmission, and so on.

Of course, Zheng Jianguo at this time returned to the state when he first saw the graphite powder on the tape, that is, he only knew what it was and didn't know why, but this is a little different from graphite powder, and the history of doctors using nitroglycerin to treat heart disease can be traced back to 1878, that is, a century ago, there were doctors who did that.

However, in this century, Zheng Jianguo does not believe that there are no doctors who have studied this phenomenon, that is to say, it is impossible to belong to the state of darkness under the lamp like the Helicobacter before him, and the biggest possibility is that it is hindered by the development of electronic technology and cannot glimpse its mechanism of action, so if you want to confirm the correctness of this idea, you can go to the library to check the paper!

As the world's top medical school, Harvard Medical School's library collects all the world's officially issued academic journals, and the huge number of collections allows the whole school to keep abreast of the latest developments in various medical fields, and the journal that Zheng Jianguo is looking for is the journal "Blood Vessels", which is named after the medical profession.

With the development of science and technology, the division of labor of human beings is becoming more and more detailed, and although the medical journal "Blood Vessels" is not as famous as "Lancet", in the field of vascular medicine, it is the holy place of all doctors in this discipline.

Through more than two years of experience in researching literature, Zheng Jianguo chose to start with the latest issue of the journal "Blood Vessels", and because his two current professional fields are 108,000 miles different from cardiovascular medicine, coupled with the fear of being targeted by the FBI who doesn't know where he is, all he can do is pretend not to pay attention to start understanding, so he didn't find what he wanted until the day before Christmas Eve: "On How Endothelial Cells Cause Vascular Smooth Muscle Relaxation"——

"Blood Vessels, March 1979?"

Quickly glanced at the cover, Zheng Jianguo knew that this was what he wanted, but after he read the above report, he found that this paper came from the well-known Furchgott laboratory, the reason why it is said to be famous, but to evaluate it from his current vision, in fact, Furchgott laboratory, as a professional laboratory in vascular medicine, has been conducting research on this phenomenon for 25 years, and this also made Zheng Jianguo begin to face up to what he did.

Zheng Jianguo is a fake researcher, his essence can only be regarded as an academic thief who is worse than Nong Shaoshan, at least Nong Shaoshan is really through his own efforts and learning, although he has reached the pinnacle of life in a fraudulent way, this is only caused by the other party's low professional ethics, and Zheng Jianguo, who steals other people's academic achievements by stealing, is a red fruit with low character.

One is low professional ethics, the other is low character, this is a thorn buried in Zheng Jianguo's heart, especially at this time, seeing that it has taken 25 years for this laboratory to touch the shadow of NO, his conscience, which has long been thrown out of the clouds, seems to have recovered the temperature, so he put the journals and magazines on the shelf, and looked at "Blood Vessels" with dark eyes and fell into the battle between heaven and man.

Zheng Jianguo knew that the reason why endothelial cells caused vascular smooth muscle relaxation was because of the effect of NO, and at this time, people had not discovered NO, or even the endothelial relaxation factor, and he could use the excuse of discovering Helicobacter to justify himself - but when this idea flashed through his mind, two completely different figures appeared in his mind.

On one side, there is a figure holding a black fork: "You have even stolen Helicobium and graphene, this NO is just an invention that can make money, and you have found out in your conscience? You don't want money anymore? There are hundreds of millions of dollars a year, and you just watch it be made by others?"

On one side, there is a figure holding a white shield: "You have also done experiments, cleaned the laboratory, torn the tape, washed the reagent bottles, and buried yourself with literature in the cold wind and rain to keep warm, the director and experimenter in the Furchgott laboratory have been unknown for 25 years, do you know how many 25 years there are in life?"

The voice of the black fork's figure became louder: "You know that they can't enjoy their discovery at all, the pharmaceutical factory will not give them even a cent of profits, all the profits of NO are used to bribe and consolidate the hegemony of the pharmaceutical factory, you take this invention now, at least you can use the identity of the discoverer to share a piece of the pie from the pharmaceutical factory-"

Bai Dun's figure lowered his voice: "You are a researcher, at least in the eyes of the people next to you, you are a researcher, you know the degree of bitter criticism of researchers, they have a bright head on their heads at a young age that only sixty or seventy years old, most of their families are unhappy, they are all slaves, slaves who can't see the end at a glance-"

The figure of the black fork said loudly: "You get the money, you can help the development of the country, you can use this money to help countless people in the republic, hundreds of millions of people every year-"

The figure of the white shield opened its mouth widely, but it couldn't make the slightest sound, only the mouth shape: "Don't-"

"Hi~"

Just when the figure holding the black fork showed a bright smile, a familiar voice appeared out of thin air, and after it disappeared in an instant, the figure of the white shield showed a triumphant smile, Zheng Jianguo turned his head to look at Ulrika with a curious face, and nodded: "Hi, Ullika~"

"Well, Zheng, what are you looking at? I'm looking at the back from a distance and it seems to be you, but this side seems to be an area of vascular medicine—"

Ulrika's brown eyes swept over the journals and magazines on the shelves, especially on the few journals on vascular medicine that Zheng Jianguo had stared at before, shrugged her shoulders and said: "Tomorrow is Christmas Eve, do you have a place to go, why don't you come to my residence to play, now the research progress is not so rushed, we decided to take a good rest, you can also drink now-"

"Well, I'm sorry, I've got a date, I'm going to get on a plane to Washington, D.C., you should relax-"

Zheng Jianguo's eyes swept over Ulrika's three-dimensional face, and the figure holding the white shield in his mind shouted loudly at the same time: "You are now the discoverer of graphene and Helicobacter, if you find NO again, it will bring you unpredictable consequences, at least you can't explain how you suddenly crossed over to vascular medicine."

Now Ulrika has become suspicious of you! If the FBI asks her about your performance, you will be targeted by the relevant departments in the United States! And the discovery of NO will only make you a little more money, but are you short of money? Do you think the hundreds of millions of dollars you get a year are worth much, or do you probably end up being targeted and becoming a guinea pig?"

"It's greed and vigilance—"

In an instant, Zheng Jianguo also made a choice, and his mind blinded by greed returned to normal under the prevention of vigilance, and when he suddenly felt a chill on his back, Ulrika had already noticed his abnormality: "Zheng, are you uncomfortable?"

"It's a little, I felt a little blind just now, it looks like I'm going to go for a check-up, Ulrika, I'll go first. ”

Waving his hand and nodding, Zheng Jianguo turned around and walked out towards the library, leaving Ulrika to see his back disappear, then turned his head to look at the journals on the shelf, reached out and stroked the magazines including "Blood Vessels", and a suspicious look appeared on his face: "Why did you suddenly start to pay attention to vascular medicine? Could it be that he has already made a new discovery? This needs to ask Charlie to check Zheng's medical exam results to see how many points he scored in the vascular exam——"

At this time, Ulrika's thoughts, Zheng Jianguo had no way of knowing, walked out of the library and looked at the sunny sky, the blue look was not like a winter day at all, after Ulrika disturbed before, he had completely recovered his sanity at this time, as the vigilance in his heart said, he is now holding the two world-renowned discoveries of graphene and Helicobacter, and then put out the blue pill of NO, it is too dangerous under this superimposed effect - life is precious, and the price of freedom is higher, this is the old saying to death!

Of course, the reason why Zheng Jianguo completely gave up NO was because it was a little too far away from his Helicobacterium, and after reviewing the literature during this time, he found that his previous thoughts about NO were too natural, not to mention the need to find out the mechanism of action of NO alone, and the Furchgott laboratory alone had studied it for 25 years and scared him.

If the mechanism of action of NO takes 25 years to discover, Zheng Jianguo will not waste his precious life on it even if he is killed, although he vaguely feels that since the difficulty of this thing is so great, then it must be worth a Nobel Prize-

Zheng Jianguo didn't know that his idea was right, and the discoverer of NO really won the Nobel Prize in Physiology and Medicine.

First it was dangerous and then it was too difficult, Zheng Jianguo had completely given up NO at this time, of course, he was not without gain in the library during this time, he was picked up by Zhao Liangliang after getting off the plane that night, and he said after making a phone call to China: "Teacher, I asked Mr. Wei Jianran to transfer your "Journal of Molecular Biology" to receive it, right?"

"I got it, but I saw that the research value in it was not great, and the reference significance from 1971 to the present is greater than the practical significance, of course I translated it, and it is good for students to refer to it-"

Professor Ye Minde's voice was a little distorted, and he didn't know if it was the other party's voice or a little hoarse, Zheng Jianguo also showed a bright smile: "Then you must also remember that there is an article by Professor Clayp in it——"

"I remember it was an article about the use of dual primers to repair replication DNA, which Clap discovered in 1969 and gave a lecture at a high conference—"

Ye Minde, who was on the other end of the phone, quickly beckoned to Tao Ye next to him, who hurriedly brought the stack of manuscripts in front of him to him, quickly flipped to the page of the article about Clayp, looked at the regular script on it and said, "Well, he also wrote about the test process——"

"Teacher, do you know that if you want to tear a million layers of graphite, you only need to fold it in half with tape 20 times, right?"

Zheng Jianguo's voice was also a little distorted, and Ye Minde, who was wearing reading glasses and full of silver hair, looked stunned, and subconsciously said: "Jianguo, you are a good student with keen observations, and the same is true of the graphite layer of Helicobacter, and the teacher has been glad many times that your dedication to research was not hit at that time, so you will miss out on Helicobacter like other students and researchers who succumb to authority——"

"Teacher, I'm not talking about my grades on the Helicobacter and graphite layers, I'm not showing you credit, and I'm not trying to accuse you of making decisions that are no different from all the teachers, in fact, I need to thank you in this regard, to say that you accepted me, a graduate student who is a little out of the way, and to say that after all, it was with your pension money that I found Helicobacter, and my gratitude to you is unforgettable——"

Zheng Jianguo's words on the phone were unusually sincere, but when these words reached Ye Minde's ears, he also understood that this phone call was not as easy as in the past, and this thing was called to talk to himself: "Okay, good, there are no outsiders here, just Tao Ye is next to you, just say what you want to say——"

"Teacher, I have an idea. ”

Zheng Jianguo glanced at Zhao Liangliang, who was playing with a Zippo lighter in his hand, and then looked at the young lady at the front desk in front of him, and said into the microphone: "Just like tearing 20 times can separate millions of graphite layers, if according to Professor Klepp's test method, I calculated that the DNA obtained in each cycle is twice that of the previous cycle, then the DNA can be amplified 1000 times after 10 cycles, and 1 billion times can reach 1 billion times after 30 cycles!!