Chapter 628 Great scientific ideas are often born in a café

Lucy hurried to the point: "Professor Shen, we at GLK are very interested in your LPJK1 project, and we want to cooperate with you. ”

"There is a partner in this project, and you know very well who the partner is, and you know me better than I know you. Shen Qi stared at Lucy with blazing eyes, she painted smoky makeup today, smeared blood-red, red to gaudy lip gloss, the biggest change was that Lucy, who originally had blonde curly hair, dyed her hair black and straightened.

Spicy eyes, Shen Qi rubbed his eyelids, this style of black straight length is not something that you Lucy can follow if you want to.

Lucy was quite happy with her new look, and she played with her blackened hair and said, "I mean, we can work with Obeqi Pharmaceuticals." ”

"Then you go talk to the business manager of Obeqi Pharmaceutical. ”

"Professor Shen, don't beat around the bush like this, right?" Lucy found that Shen Qi was very wary of her, and this was not a situation she wanted to see.

The active compound of LPJK1 has just been made, which is a very secret thing. Lucy is an Englishman, she doesn't come early or late, but when she comes to visit at this time, Shen Qi will of course be vigilant: "Lucy, you have 7 minutes and 24 seconds left." ”

"Whew......" Lucy couldn't help but take a deep breath to calm down, she felt that today's Shen Qi had a strong suppressive force, and the amiable Shen Qi last time was completely two people.

But think about it, last time Shen Qi represented China and Britain in state-to-state exchanges, with a strong sense of diplomatic ritual.

On diplomatic occasions, Shen Qi will of course be amiable and kind.

Today, Lucy visited the famous scientist Shen Qi alone as a representative of the company, and Shen Qi could not see her at all, or arrange a subordinate to deal with the matter.

Shen Qi took ten minutes to invite Lucy to coffee, which was already a great way to save face for the British woman.

Lucy took a sip of coffee and said: "R anemia is a rare disease, and only by opening the global market can we maximize the benefits. ”

This sentence finally gets to the point.

Shen Qi silently tore open the sugar packet and poured it into the coffee cup, stirring it slowly, as if thinking.

A new drug can be sold in China, not necessarily in the EU and the US.

Animal experiments and clinical trials have been done in China, and they have to be done again in the EU and the United States.

The FDA has the strictest review standards in the world, and even if the compound is made in accordance with the FDA standards in the preclinical research stage, it may not be able to pass the FDA review and enter the U.S. market. There are a lot of factors involved in this, technology, PR and even luck.

OBEQI Pharmaceutical obviously does not have any overseas resources, and if it wants to open up overseas markets, it needs to spend a lot of money and it will take a long time to operate. The development of drugs burns money, and the market operation also burns money.

Compared with foreign countries, China's rare drug protection policy is still improving. Shen Qi has predicted that if LPJK1, a rare drug, is only sold in the Chinese market, it will definitely lose money.

Shen Qi's original intention of doing LPJK1 was to save his wife and patients similar to his wife.

The original intention is correct and majestic, but in the specific implementation link, you can't lose money.

The pharmaceutical industry must have enough sales and sufficient profits, otherwise the pharmaceutical company will soon go bankrupt.

Many pharmaceutical companies have declared closure because they have failed to develop and sell a new drug.

Therefore, most small and medium-sized pharmaceutical companies sell compound patents to large pharmaceutical companies after animal experiments or clinical phase I, because large pharmaceutical manufacturers have a big business and can afford to consume them.

Shen Qi said: "Lucy, let's do it, after doing animal experiments, I will arrange for you and the business leader of OBEKI to discuss the overseas operation of LPJK1." ”

"Waiting for your good news. Lucy breathed a sigh of relief, this negotiation was actually a bit unconventional, after all, the animal experiments on LPJK1 had not been done.

Shen Qi sent Lucy to the door of the central building, and he kindly reminded him: "Lucy, you dyed your hair black and straightened it, this style is not suitable for you, let's return to your original golden curls." ”

"Oh, that's so sad, I've been doing this all day!" Lucy was devastated that her hairstyle was more important to her than her business.

Under normal circumstances, compounds that have been tested on animals will attract the attention of pharmaceutical predators. Compounds that have not passed animal experiments are of no value, and it is unknown whether the two dozen active compounds of LPJK1 can pass animal experiments.

After all, Shen Qi is a winner of the Philippine Award and a winner of the Promise, and his name is a gold-lettered signboard, which gives Lucy confidence.

Anyway, Lucy's initiative didn't cost GLK a penny, the coffee was still invited by Shen Qi, she drank two cups, a mocha and a latte.

After drinking, with Shen Qi's consent, Lucy also took away the custom-made, commercially unavailable, exquisite coffee cup full of high-tech elements made of metal and glass materials, and the coffee cup was printed with Shen Qi's quote: "Great scientific ideas are often born in coffee shops." ”

After sending Lucy away, Shen Qi immediately arranged for his subordinates to apply for patents for more than two dozen active compounds of LPJK1.

Originally, this work was done while animal experiments were being conducted, and there was no need to apply for patents for active compounds that caused obvious side effects or even death in experimental animals.

Now, Shen Qi is very vigilant, and while cooperating with foreign parties, he must also be vigilant against foreign parties.

Last time, Shen Qi took Lucy to visit their laboratory, and today Shen Qi only let Lucy drink coffee in the central café, and at most gave her a custom-made coffee cup, that's all.

Shen Qi arranged for a general to run the patent registration: "He Lin, stop the experimental work at hand in your group, what you have to do now is to go to the patent office, and the product patents, intermediate patents, synthesis method patents, and combination patents of more than 20 active compounds of LPJK1 are all registered." At the same time as running the domestic patent office, you should also apply for PCT, which you should be familiar with. ”

The PCT stands for International Patent Application, and this organization has more than 100 member states. He Lin smiled: "Director Shen's desire to survive is very strong, is he so insecure?"

"He Lin, you studied in a capitalist country, you know the nature of capitalism very well, and in order to obtain the maximum benefit, they will do whatever it takes. You can't have the heart to hurt others, and you can't have the heart to defend people. Speed speed, this thing is over, everyone has a holiday, I will take everyone to the outdoor team building activities to relax. ”

Shen Qi was heartbroken for the LPJK1 project, and his dear wife was not idle.

Ou Ye and three students are working on a strong BSD conjecture.

One teacher, three students, all quite Buddha. They also do not apply for scientific research funds, nor do they report projects to the state, and Ouye pays out of their own pockets to carry out research on topics that strengthen the BSD conjecture.

Compared with the extremely expensive drug research and development, the research of purely theoretical mathematical topics does not cost a few dollars.

A few computers, a few whiteboards, a few boxes of A4 paper, a few boxes of pens, a few cups of coffee, a few bottles of boiled water, a few takeaways, and all the equipment and materials to spend money on.

Xiaoyun said in a tone of memorizing the text: "Professor Shen has made a wonderful argument in the History of Number Theory: in order to prove the BSD conjecture, you must first be familiar with the Hasse conjecture, and then, you have to prove the Taniyama-Shimura conjecture yourself and use Wiles's method to prove it. When you make this point, you are not far from proving Fermat's theorem, so please go ahead and use Mr. Andrew Wiles's elliptic curve method to prove Fermat's theorem. ”

If you proved Fermat's theorem, continue reading below, otherwise skip to the next chapter. In the following article, you can use the pattern of the Riemann zeta function to extend L(E,s) to a function that can give an answer to any complex number s. In order to make it easier for you to understand the content of this chapter, I suggest you read another book by me, "The Riemann Hypothesis Proof". ”

"Xiaoyun, don't tell me that you can recite the full text of "The History of Number Theory"? That book has hundreds of pages!" Of course, Zhao Tian has also read "The History of Number Theory" written by Shen Qi, which is an elective textbook for undergraduates of the School of Mathematics of Yan University, and is also a compulsory textbook for the Department of Mathematics at Princeton.