Professor Qu is very particular about washing his hands, first washing with soap, and at the same time carefully brushing with a small brush, and the skin folds are the key areas of brushing. After washing, rub with iodine wine, and apply alcohol after wiping.

Professor Qu turned off the faucet not with the palm of his hand, but with his elbow. This is done to avoid recontamination of the white palms with germs.

Shen Qi copied and pasted Professor Qu's hand-washing operation, and he said while washing: "To tell the truth, the medical laboratory of our center is indeed in the process of employing people, and at this stage it is mainly engaged in the research and development of chemical drugs. Pharmacy is an extremely large and complex discipline that encompasses more than just chemistry. ”

"Chemical drug synthesis is a very applied scientific research work, and it is not difficult to dig up some application-oriented elite talents. It is very difficult to dig up scholars who study basic medical theory, and basically no one studies this major when Chinese students go to study abroad, and it is difficult for foreign researchers of basic medical theory to come to China to work. Personally, I attach great importance to the fundamental theoretical aspects of mathematics, physics, chemistry, biology and medicine. Therefore, Lao Qu, we should still increase efforts to train local researchers of basic medical theories. ”

"It's the engineers who do drug synthesis. Those who do basic theoretical research in medicine are masters. Shen Qi turned off the faucet with an elbow and returned to the office with Professor Qu.

"Director Shen, you have said so much, it is nothing more than asking for people. As I just said, you can take these students of mine away. You can take it, including me. "Professor Qu is very generous.

"Then it's settled. ”

"Take it, take it, take it, take it. Professor Qu waved his hand and agreed.

Shen Qidong looked around, but didn't find what he was looking for: "Lao Qu, don't you have coffee here?"

"As a medical practitioner who has been practicing for 30 years, I recommend that you drink less coffee and more boiled water. Professor Qu poured a glass of boiled water and handed it to Shen Qi: "Director Shen, you said that you are a master who does basic medical theory research, and I strongly agree with this. I have been studying anemia for many years, thalassemia, Fanconi anemia, I have studied all these diseases, and I have made a little bit of progress. Let's talk about severe thalassemia, it is a hereditary disease, the treatment plan is not complicated, blood transfusion, iron removal. In more severe cases, the spleen is removed or a stem cell transplant is performed. ”

"Anemia type R is not hereditary, but the disease is more complex, much more complex than thalassaemia. At present, the best drug on the market is this capsule from GLK, but you and I both know that this drug is sold expensively, but it cannot solve the fundamental problem. It can only be said that after taking GLK's medicine, the patient's quality of life will be slightly improved. Without taking this medicine, the patient will suffer more. We also want to do gene activation therapy, but there is no new drug for this. Without new drugs, no matter how good the clinicians are, they can't come up with a better treatment plan. Director Shen, I have a general understanding of the LPJK1 project in your center, and I heard that LPJK1 is a gene activation therapy drug?"

"Yes. Shen Qi nodded.

Professor Qu asked, "You haven't entered animal testing yet, have you?"

"It's coming. ”

"I hope you can succeed and save people's lives, and your merit is immeasurable. By the way, how is your wife's health doing?"

"The same old way. Shen Qi patted Professor Qu's documents and said, "Can I make a copy of the diagnosis and treatment observation records of these patients with type R anemia and take them back for study?"

"Of course. ”

"Thank you, then I'll take my leave. ”

Shen Qi's purpose of visiting the hospital had been achieved, and he returned to the center and convened a meeting of all the members of the chemistry laboratory.

Shen Qi told Professor Qu that it is the engineer who does the synthesis of drugs, and the master who does the basic theoretical research.

It's such a reason, if a scholar who studies the basic theory of medicine produces results, he is basically going to the Nobel Prize in Medicine. Those who do drug synthesis also have the opportunity to win the Nobel Prize, but the forced standard is certainly not as high as that of the basic theory.

Compared to other fields, pharmaceuticals are the most technically demanding. There are many Nobel Prize winners in internationally renowned pharmaceutical companies, and there is not much difference between what they do from academia to industrial application, which is also medical academic research, medical theory to applied research.

In many other fields, academia and industrial applications are basically separated, people who study mathematics leave academia to go to the sea to become investment banks, people who study the microstructure of materials go to work new energy vehicles, and people who study computers do everything.

Academics despise the mercenary motives of industrial applications, believing that they have been corrupted by sugar-coated shells.

The industrial application community is not accustomed to the stubbornness of the academic community, what is the best thing in these years? Of course, it is money.

Shen Qi also has this kind of contradiction in their center, and this contradiction is difficult to completely resolve, so they can only try to adjust it.

This contradiction in the chemical drug laboratory of Shen Qi Scientific Research Center is the shallowest one, in the field of drug research and development, academic research and engineering application are closely linked, and the division is not obvious.

"LPJK1 has entered a critical stage, and everyone will work hard for a while to make a few more samples. After the meeting, Shen Qi entered the chemistry laboratory and conducted experiments with the researchers.

"In the 0202nd experiment of LPJK1, the S-rearrangement reaction was carried out with azatriazole and 1,3-dithiane as the starting material...... "He Lin became the main operator.

The S-rearrangement reaction was invented by Shen Qi, and the international chemical community has not yet officially named this new type of rearrangement reaction.

"Heated to 200 degrees Celsius, thermocyclization ...... The intermediate is formed, malonic acid is added, and the S rearrangement is ...... again" The assistant Cao Fan assisted Mr. He Lin very slippery, after all, he is a doctoral student of Yan University, and his understanding ability is very strong, and he has achieved proficiency in operating the new type of S rearrangement reaction in a short time.

Regardless of whether it was Newton or Leibniz who invented calculus, they agreed on the same definition of calculus, which was a new mathematical tool for solving other mathematical or physical problems at the time.

Shen Qi's invention of the S-rearrangement reaction is also a tool, of course, the academic significance of the S-rearrangement reaction cannot be compared with calculus, after all, there are too many existing organic synthesis reactions.

"The final product should be an eight-membered heterocycle, and hopefully the yield will be higher...... Photocatalysis, de-side chain ......" Cao Fan did the experiment very handy, which attracted Shen Qi to nod and praise.

The LPJK1 project has reached this stage, and it is no longer just a project for the synthesis of rare anemia drugs.

The purpose of this project is to develop a drug for type R anemia with high yield, low side effects and significant efficacy, and in the process of development, new things such as novel rearrangement reactions and stable synthesis of macrocyclic compounds are incorporated.

Novel rearrangement reactions and macrocyclic compounds are very academic, while drug synthesis is an engineering application.

It turns out that in the top chemical laboratories, academic research and engineering applications are very closely combined.

The synthesis of a new drug requires not only a profound academic theoretical researcher, but also a skilled engineering application operator.

The LPJK1 experiment is still progressing in an intense and orderly manner, and Shen Qi is sitting in the laboratory, and he feels that he is about to produce results.