Chapter 82 Protection
"It's good to drink, it's good to drink. Li Mao nodded, "Old Lu...... Farewell, you came just in time, I'll bring you two boxes of candy and go. ”
"Hey candy?" Lu Weibei's brain was already down.
She's really here to consult a patient with an advanced tumor, right?
"My son, who has graduated with a doctorate and is studying automation, will send some candy and celebrate for him!" Li Mao said proudly.
"Ah, thank you, thank you, congratulations!" Lu Wei didn't hurriedly take the candy and thanked him.
Li Mao and his wife looked at her expectantly with joy and restraint on their faces.
Lu Weibei hesitated for two seconds, thought about the cup of Pu'er tea, and clenched his fists.
"It's not easy to graduate with a doctorate, which school did your son study?" Lu Wei said.
Li Mao and his wife seemed to have received an amnesty, and began to talk endlessly about how good their son was.
Li Mao and his wife did not have a university education, but they respected the reader very much in their hearts, named the child Li Zhishu, and always hoped that he could learn knowledge well. The family was not wealthy at first, and they often bought old books to read to their children. After coming and going, the child really became interested in learning.
Later, due to the demolition, their family began to become more affluent, and they put their children's extracurricular classes in the first place in spending.
Now Li Mao and his wife have several houses collecting rent, and they have also opened a small fruit stall, Li Zhishu graduated from one of the top universities in China and found one of the best jobs.
"After he went to college, we threw him a thank-you banquet. Thank you for the teacher's banquet, you always have to toast other teachers, don't you?" Li Mao told the story from Li Zhishu's birth to his doctorate graduation, and his voice fell, "Who would have thought that the wine would send me here." ”
Lu Wei was stunned.
Li Mao sighed, "Don't say goodbye, don't hide it, everything has passed through in my life, it's worth it! Life and death, I actually don't care, but Xiaoshu is different, if I really can't do it, he will regret it for the rest of his life." So, no matter what, I'm going to live, I'm going to live. Any kind of treatment plan, as long as you think it is effective, you can mention it, I will definitely cooperate! Money is not a problem, it really can't be done, let's sell a few houses. ”
Lu Wei hesitated for a moment, "Uncle Li, in your current state, it is difficult to recover, but we can find a way to extend the survival time." I suggest that you still talk to your son about your current physical state, which is not caused by that meal or drink, so that he does not have so much psychological pressure. ”
"Well, who hasn't?" sighed Mrs. Lee, "but what can be explained? ”
"So, we don't expect any recovery, if we can make me feel better, let him get over this hurdle. Li Mao said.
Lu Weibei nodded, "Okay, then let's start now." Your current condition, the doctor does not recommend surgical treatment, so we will mainly talk about several possible options for medical treatment. ”
Li Mao and his wife nodded and listened carefully.
Lu Weibei talked about all the situations and found that with FAP chemotherapy, Li Mao's survival time was the longest, about three years.
This FAP chemotherapy regimen is a three-drug combination regimen, because the side effects will be stronger with the addition of ADM drugs, and it is generally only recommended for patients with good heart and kidney status.
Lu Weibei hesitated for a moment and concluded, "Uncle Li, at present, it seems that the FAP chemotherapy regimen is most likely to maximize the survival time...... However, the side effects of this regimen are significant, and you may experience pain during the treatment......"
"Girl, do you mean that I can live a little longer with this plan, but it's just uncomfortable?" asked Li Mao.
"Yes. Lu Weibei nodded.
"What's so uncomfortable?" asked Mrs. Lee.
"Everyone's reaction to medication is different, and I can't say this well. The patient may feel the changes and may have reactions such as nausea, vomiting, stomatitis, hair loss, and high fever. Of course, we will also have some medication to help control the symptoms, and the patient will not be left to suffer these pains. Lu Wei said goodbye.
"That's it?" Mrs. Lee breathed a sigh of relief.
"Huh?" Lu Wei didn't react for a moment.
"What is this? Don't you know, our Lao Li once worked at the construction site before, and was smashed by a wooden board with a bowl-sized hole, and the stitches alone are seven stitches. At that time, the place was remote, and he didn't have any anesthetic. It's all over the place, what's the matter?" Aunt Li said.
"You can't say that...... The side effects of chemotherapy drugs are long-term and may not go away for several years. In a sudden situation like trauma, the body secretes adrenaline, which makes people feel less painful. But for chronic pain like stomatitis, adrenaline doesn't help. Lu Wei said goodbye.
Uncle Li waved his hand, "Isn't stomatitis just a rotten mouth, that's not a problem! It's not a problem to want to vomit like something nausea, when Xiaoshu was pregnant before, she vomited every day, so didn't she also carry it off." It doesn't matter if I lose my hair, I shave my head and I don't mess up my family. ”
"Oh, we were worried before, it's only a few days, I didn't expect this day to be counted by year, this is a good thing, a good thing!" Aunt Li said.
"Yes, maybe we can wait for our little book to get married. Li Mao said with a smile.
Lu Weibei also smiled, "That's good, then the rest will be left to your oncologist." ”
"Well, wait a minute, wait a minute, is this side effect going to happen from the beginning of taking the medicine?" asked Li Mao.
"I may not start the same day I eat it, but the side effects will start in the next few days, maybe a week or so. This is also related to the human physique. Lu Wei said goodbye.
"That's not good, that's not good, that little book, I can't get over this hurdle in my heart, that's not good. Is there a way to have fewer side effects?" asked Li Mao.
Lu Weibei gritted his teeth, "Uncle Li, this is not a joke, can we try it, tell Mr. Li first, and then make a decision?"
"Yes, you can't leave this disease untreated, Xiaoshu, I'll adjust it. Aunt Li also advised.
"You two don't understand. Who doesn't know that this cancer doesn't grow in a day or two? It's all terminal, and everyone knows that it's not a glass of wine. Li Mao sighed, "But if I start with that glass of wine, my body will never get better, then he will always remember that day, and remember that it was from that glass of wine that my body will not be able to do it." Let's use targeted drugs, I've heard that the side effects are small. ”
"But you still have a long time to live, Uncle Li, you do have a HER2 gene mutation that can be specifically killed by targeted drugs. But the drug corresponding to this mutation is lung cancer, breast cancer and other cancers, and there is no evidence that these drugs can work on liver cancer, which is too risky. Lu Weibei shook his head, "And even if it carries this gene mutation and can be controlled by the corresponding drugs, the abundance of such cells is too low, only seven percent of tumor cells carry this mutation, which is very dangerous." This means that the tumour cells will quickly become resistant to the drug and there is no way to control the condition. ”
In fact, if targeted drugs are used, Li Mao will only have 139 days to live.
"No, what do you mean when you just said drug resistance?" Li Mao asked.
Lu Wei didn't think for a moment, "Survival of the fittest, survival of the fittest, have you heard of this?"
"Yes, yes. Li Mao nodded again and again, "Doesn't it mean that you have to work hard to adapt to the environment, and only by adapting to the environment can you survive." ”
Lu Weibei nodded and said, "Yes, that's what it means." Did you know that the survival resources in this world are limited, and species that adapt to the environment will squeeze to death species that are not adapted to the environment?"
"You're not right! We're going to make the cake bigger together, and we can't think about squeezing anyone else to death. Li Mao said.
...... It seems that this concept needs to be explained in detail.
Lu Wei didn't think for a while, "You're right, then let's not discuss practical issues, let me make an analogy, if there are now a hundred white rabbits, ten black rabbits, and each pair of rabbits can give birth to two, then after they all give birth to children, how many black rabbits and how many white rabbits?"
"Do all the rabbits they give birth to are the same color as them?" asked Li Mao.
"Yes. Lu Wei nodded.
"What did the white rabbit and the black rabbit give birth to?" asked Aunt Li.
“...... We stipulate that white rabbits can only be with white rabbits, and black rabbits can only be with black rabbits. Lu Wei said goodbye.
Li Mao and his wife nodded and snapped their fingers.
"Three hundred white rabbits, thirty black rabbits. After a while, Li Mao raised his head.
"No, two hundred white rabbits, twenty black rabbits!" Aunt Li interrupted.
"Well, two hundred white rabbits, twenty black rabbits. Lu Weibei immediately gave encouragement, and quickly advanced the topic while secretly scolding himself for making too much of a detour, "So, there are two hundred and twenty rabbits now, but the existing food can only feed two hundred rabbits, so among these rabbits, black rabbits and white rabbits, do they all have to die?
"Gee, why is this so cruel. Aunt Li complained.
“...... Yes, I'll make an analogy later. Lu Wei didn't bow his head and admit his mistake, and continued to advance the topic, "But this time, let's make do with this example." I went on, but if all the black rabbits were killed before they gave birth, then there would be only 200 white rabbits after breeding, and there would be enough food to eat, and all of them would survive. In the end, 200 white rabbits were all alive. ”
Li Mao and his wife nodded as if they didn't understand.
The atmosphere was a little awkward all of a sudden, Li Mao stepped forward and snorted, "Cough, this should be said to Xiaoshu, he is smart and can understand." We're a little confused, don't you mind. ”
"No, no, you have a clear mind!" Lu Weibei hurriedly said to reassure, "Actually, what I mean is that this black rabbit is a tumor cell that carries a gene mutation, this black rabbit is a targeted drug, and this white rabbit is a tumor cell that cannot be killed by a targeted drug." As for the environment where food is limited, it is the human body. Cells with mutations and cells without mutations are competing for proliferation in the body because of limited survival resources. The use of targeted drugs, just like killing a black rabbit, not only cannot control the tumor, but may also make other tumors grow better. ”
"That's not right, I look at others, there are many people who use targeted drugs very well, we have a neighbor who has lung cancer, so he takes targeted drugs, and he has lived for almost eight years, and there is nothing wrong at all!" Li Mao said.
"Targeted drugs are certainly useful, but before using them, we have to consider how many cells can be killed by this targeted drug. Do you think, if we just killed a white rabbit instead of a black rabbit, wouldn't the effect be more obvious? After breeding, there can only be forty rabbits. Lu Weibei explained.
Mr. and Mrs. Li Mao nodded.
"But this black rabbit is dead, it's still a little useful, right?" asked Li Mao.
“...... Yes, but very limited. Lu Wei said goodbye.
"Then I think we can try it first, no, let's go to chemotherapy again." Li Mao said.
"Uncle Li, we don't know the development of the tumor in your body now, and if you blindly try targeted drugs, it may make the situation worsen very quickly during the attempt. And as I just said, the matching drug is not for liver cancer, and it is difficult to say whether it can be controlled. Lu Wei said goodbye.
"Let's just try, try, try. Li Mao said, "How long will it last?"
“...... This also varies from person to person, some people may not have any effect at all, and some people may have a tumor shrinking within a month or two. Lu Wei said goodbye.
"Yes, a month or two. After that drug fails, let's have chemotherapy!"
"The use of targeted drugs first, followed by chemotherapy, is also a plan. If that's the case, I suggest you ......," Lu Wei said tentatively.
Numbers appeared above Li Mao's head.
Lu Weibei looked at the string of numbers, beating little by little, and finally stopped at 375.
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