Chapter 515: Awesome, Bioscience Laboratory
The idea proposed by Xiao Jianguo is actually not new, and there are people doing this in Shanghai. It's just that Xiao Jianguo and Xiao Jianying already run an environmental protection company, so it will be easier to do this.
However, Xiao Ming is not optimistic about this idea, the reason is very simple - there is no technical content.
Your company can recruit garbage sorting and recycling staff to collect garbage, and other companies can also do garbage sorting and recycling, which is something that does not have any technological content.
If there is capital involved, then it will be the same as the original shared bicycle and takeaway APP to burn money to grab the last chicken feather in the market.
Xiao Ming said: "If you don't have core technology, don't invest rashly. People who do business are very smart, today we think of the way others will think of tomorrow, even if we occupy the market of garbage classification, it will definitely be a big investment and a small return, and there is a possibility of being replaced at any time. ”
Xiao Ming's words are actually the true meaning of the development of Pangu Technology to today, and only with core technology will it not be afraid of competition.
Xiao Ming painted a big cake for Xiao Jianguo and said: "Environmental protection companies can still do it, and garbage classification must also be done, but all this can be handed over to machines instead of people, and people are inert." After the year, Pangu Technology will study a detailed plan for garbage classification and treatment methods, which can be shared with Uncle at that time. ”
Xiao Jianguo is definitely willing to listen to Xiao Ming's advice, after all, in the operation of the company, Xiao Ming is much more sophisticated than Xiao Jianguo, who has been a public official for decades.
In the afternoon, Xiao Jianguo and Liu Xiong continued to be students and listened to Xiao Ming's lectures.
Zheng Xuanyu and Lin Weiwei are also familiar with each other, Lin Weiwei listened to Zheng Xuanyu talk about what happened in the medical laboratory, and realized that the laboratory was not a monotonous life, but a rediscovery of the world.
After dinner, Xiao Ming sent Zheng Xuanyu downstairs to go home.
It's not Chinese New Year's Eve yet, but there is already a New Year's atmosphere in Jiangcheng at night.
The bright fireworks in the night sky and the bright lights in the community are all heralds the arrival of the new year.
Jiangcheng is one of the few cities that allows citizens to set off fireworks on the streets, and after the pollution has eased, the city still allows people to enjoy that happiness at the end of the year and the beginning of spring.
"That's it, go up. Zheng Xuanyu walked to the parking lot.
"Remember what my mom just said?" Xiao Ming asked.
Zheng Xuanyu just covered her mouth and snickered, "Let me come to play often." ”
The fiery red fireworks reflected on Zheng Xuanyu's face, and a gentle flame also appeared in her deep eyes......
The citizens of Jiangcheng are still immersed in the atmosphere of the festival, but the Pangu Science and Technology Park is busy on the first working day after the festival.
With the increasing supply of C14 micronuclear materials in Nananfei, Tianhe new energy vehicles will achieve mass production this year.
The busiest is still the life science laboratory, and many experimenters take the initiative to work overtime in the laboratory during the Spring Festival, and there is a decisive breakthrough in the research on the Ebola virus.
Gao Siqi, who went home for the Spring Festival, came to the laboratory early to command, and Zheng Xuanyu also became Gao Siqi's most powerful assistant, she will be fully responsible for the follow-up treatment, which is quite important work.
"The Ebola virus is 970 nanometers long, filament-like, and belongs to a single-strand negative-strand RNA virus with 18,959 bases, an envelope, and a fibrous surface with a pure virion composed of a helical ribonucleucle-shell complex, containing negative-strand linear RNA molecules and 4 virulent structural proteins. ”
Gao Siqi said: "We start with this envelope, which is the envelope, its glycoprotein recognizes and binds to the host surface receptor, then the viral envelope binds to the host cell membrane, and finally the viral capsid and viral genome enter the host to complete the infection process." ”
"Whether it's the capsule or the glycoprotein on its surface, it belongs to the gene expression of the base combination. That is, no matter how the virus changes the glycoprotein that expresses it in the process of replication and proliferation in the future, it is actually the expression of genes. ”
"The body's antibodies can't recognize the virus, and the envelope of the virus can quickly recognize and fuse with human cells, which is the biggest contradiction. ”
Xiao Ming knew that the laboratory already had the perfect solution, and said, "So what?"
"Ebola's glycoprotein changes after continuous replication, so I would like to thank Super Xiaochu here, she used the most perfect mathematical thinking and biological logic to find the only commonality of these different glycoproteins, and this commonality at the molecular level, we also located it.
Our method is to tell the body's immune system about the glycoprotein characteristics on the surface of Ebola's envelope, and increase the number of NK cells in the body through drugs, relying on NK cells to defeat Ebola on their own. ”
"The way the immune system memorizes is similar to that of traditional virus vaccines, except that the traditional vaccine uses an inactivated viral shell, and we use the common molecular spot of multiple forms of Ebola as the antigen. ”
"Xiao Chu, open the screen!"
The video shows a microscopic video of the results of the laboratory's research.
Gao Siqi said: "In fact, telling the immune system to let it recognize the Ebola virus, like vaccination, is not very difficult, but the more difficult is to artificially increase the content of NK cells. ”
NK cells, also known as natural killer cells, are important immune cells in the body. At present, in the life sciences, the origin of this type is not very clear, and it is generally derived artificially in the bone marrow, and development and growth also depend on mature bone marrow cells.
In past studies, NK cells have been induced by culturing thymocytes in vitro in the presence of cytokines such as IL-2 under laboratory conditions, but this induction is extremely costly and the cell mortality rate is extremely high.
How to increase the body's NK cells?
The traditional way is to take Ge-132, or to use in vitro culture and then deliver it into the body.
However, both methods have drawbacks, first of all, the premise of taking Ge-132 to improve NK cells is that the body's immune system is not attacked and is not controlled by Ebola, then it can release signals to produce NK cells.
If you are attacked by Ebola, no matter how much Ge-132 you take, the immune system will also send instructions to prevent NK cells from being produced.
In vitro production of NK cells in vivo delivery is also very unreliable. First of all, the cost is high and the technical difficulty is high, and secondly, under the interference of the virus, a large number of NK cells from the outside world enter the body at this time, in order to cause a complete disorder of the body's immune system, not only will not destroy the cells infected by Ebola, but will also cause new troubles.
Gao Siqi said: "So there is only one way, at the first step of the immune system being affected by Ebola into the body, it sends a command to let every cell in the body produce a large number of NK cells, and destroy Ebola and the cells infected by it in the first place." ”