Chapter 516: This Cell, Super Fierce!

Gao Siqi said: "This time, we are using a similar approach to treating cancer, and the treatment of cancer is that we use gene-inducing drugs to block the gene expression of tumor cells. Now, we are also using gene-inducing drugs, but to stimulate the production and expression of NK cell populations in body tissues. ”

Gao describes it here as a group of NK cells, rather than a single NK cell, because the immune effect of NK cells must be coordinated with other cells of the same type, such as NKp46, NKp30 and NKp44, and other natural cytotoxic receptors.

The totipotency of somatic cells is very low, and Pangu Technology has overcome this problem with gene regulation and expression technology two years ago, and this time it is also based on this method to stimulate the production of NK cells, so that every somatic cell is a battlefield to fight against Ebola, even if the Ebola virus has completely invaded the human immune system, human beings can also stimulate the vitality of the remaining cells through external treatment, and carry out a comprehensive strangulation of Ebola.

Gao Siqi said: "If this treatment can be successful in the clinic, then we will make a major breakthrough in the war against the virus, and we will be able to successfully treat the influenza virus and even HIV in the future."

"Moreover, our treatment has advantages over the Maple Leaf vaccine. The Maple Leaf vaccines can only be administered in advance, and are ineffective against Ebola branch viruses, nor against Ebola multi-generational breeding. Our treatment is after the infection, even if the disease reaches the middle and late stages, it can still be perfectly treated. ”

Xiao Ming voiced his concerns, and he said, "What about the side effects?"

"Theoretically, local NK cells will follow the blood flow throughout the body after killing Ebola-infected cells," Gao said. If you are a person with an average physique, it will not be a big harm. If you are a person with allergies, it may cause a series of immune diseases, and if you are pregnant with a baby, then you may need to pay attention to the development of the fetus. As for the specific manifestations, only experiments are carried out in the clinic. ”

"Have you started clinical trials?"

"I reported to the relevant departments on the first day of the Spring Festival working day, but ...... There is no Ebola in Xia Guo. Gao Siqi is having a headache about this.

Perhaps it was because his mind had been on the experiment during this time, Gao Siqi rubbed his temples and couldn't think of a better way, "It's a good way to do experiments in Nan'anfei, but experiments are always experiments, and there are risks, if they fail and cause the death of the patient, we can't do it." After all, the epidemic area is under the attention of the WHO and the Western media. ”

Zheng Xuanyu took out the thinking of medical experiments at this time and said: "This time, our main means is to use the NK cell population in the human immune system, and the NK cell population is not only effective against the Ebola virus, but also against the ordinary flu.

In the method of medical experiments, there is an experimental method that is analogical experiment, assuming that drug A is effective for both A and B, and the difficulty of A is lower than that of B, then drug A can be used to experiment on A, and if it is successful, it will be tested on B.

This method of experimentation is gradual and is also a means for many university laboratories to apply for funding.

XXX university laboratories will say to the relevant departments at the higher level: "Look, our drugs are all effective against A, and they are fast against B, but they are still a little short of funds, ask for support!"

Zheng Xuanyu completely came up with the idea of a medical experiment in a university laboratory, she said: "If our treatment is effective against influenza, then we will form a report and apply for the WHO to directly enter the clinical trial in Nananfei." ”

Skipping the animal experiment and entering the clinical treatment in the fastest time is Zheng Xuanyu's request.

Xiao Ming immediately said, "I agree, let's use the influenza virus as a clinical experiment first, volunteers should be easy to find." ”

At this time, Wu Qiwen, the little brother who did the virus isolation experiment in the laboratory, raised his hand and said, "What other volunteers are you looking for, it's me." I didn't pay attention to it when I went home during the Spring Festival, and I got the flu, and I didn't get better after three days of hanging injections in the hospital at home, and now it's just right, free treatment. ”

Wu Qiwen was wearing a thick mask, and he took leave because of a cold a few days ago, and today he also came to continue to ask for leave and handover work, because his condition is more serious.

Wu Qiwen complained and said: "In the small county hospital where our family is located, I saw a cold, first prescribed me more than 200 medicines, took it for three days and did not get better, and then prescribed me a drip, and then infused me for three days, which cost me more than 1,000 yuan before and after. ”

Wu Qiwen has been fighting the virus throughout the Spring Festival, and he has never been comfortable.

A cold costs more than a thousand or two thousand, and it's normal now.

Gao Siqi immediately arranged, "Yes, let's analyze the disease strain and antigen first." ”

Wu Qiwen's cold virus was analyzed, and it belonged to the common influenza A.

The usual treatment is definitely anti-inflammatory and antiviral, and then wait for the body's immune system to completely defeat the virus, and the whole event needs to last two weeks or even longer.

If NK therapy is used, then the virus will be destroyed very quickly and the body will recover in a very short time.

After a day of pathological analysis and dosimetry, Wu Qiwen received an injection of gene inducer.

Gene inducers automatically seek out cells that are attacked by the virus, and finally settle in the vicinity of infected cells, where normal cells settle and activate tissues to continuously produce NK cell populations.

On the day of the injection, Wu Qiwen felt pain in the joints all over his body, and he also had a little fever and fever, and his throat was swollen and sore by the way.

After using the NK gene induction preparation, the fever subsided in half an hour, and the pain was no longer in the evening session.

At noon the next day, the experimental team took blood from Wu Qiwen to test the blood picture and virus infection, and found that the immune indicators of the blood picture had increased significantly, among which the number of NK cells had increased significantly, and the number of viruses in the blood was only one-tenth of yesterday.

On the third day, Wu Qiwen was comfortable, his nose was yellow, and his body was recovering rapidly.

On the fourth day, the influenza virus in Wu Qiwen's body completely disappeared, and he also completely recovered his health.

In only four days, the influenza virus, which had been arrogant in Wu Qiwen's body for more than half a month, was defeated, and he himself did not go through the painful process of treating the flu in an ordinary way after injecting the NK gene inducer.

Gao Siqi and Zheng Xuanyu recorded the entire clinical treatment process completely.

Xiao Ming immediately said after reading it: "The laboratory has made a meritorious service! If it is written as a paper, it can guide the entire viral medicine community."