Chapter 174: Yes! Change the car...... (Ask for subscription)

174:

Bai Ye found the scientific research process of Danshen Dripping Pill from the Internet, because it is a decades-old drug, so a lot of papers have been published on the Internet, and many drugs similar to Danshen Dripping Pill have been produced.

At present, there are at least fifty or sixty kinds of Chinese patent medicines and liquids made of salvia and notoginseng on the market, and Bai Ye gritted his teeth and bought each of them.

After continuous separation and purification, Bai Ye was surprised to find that in fact, the specific pharmaceutical ingredients contained in these different preparations were different.

For example, compound Danshen Dripping Pill uses Danshensu and Panax notoginseng saponins, but there is a kind of Danshen tablets that use cryptotanshione, Danshen lipid 2A and Panax notoginseng saponins, Bai Ye is a little curious, what is the difference?

Because they are all common drugs on the market and can withstand clinical research, Bai Ye began the process of frantically inquiring about information.

Bai Ye suddenly understood Liu Lao's good intentions, an old drug, from research and development to the present decades, has been studied very thoroughly, trying everything he can think of, and doing experiments on every molecule or compound found to study his efficacy and toxicity.

Liu Lao's meaning is to let Bai Ye be exercised in this process, he believes that Bai Ye's strength can find stable artemisinin complexes in artemisinin, and such a person's thinking ability and innovation ability can stand the test.

Liu Lao asked Bai Ye to make Danqi Blood Activating Pills, hoping that Bai Ye could find out the differences between these drugs on the market, why there are these differences, why some molecules are removed, and why some compounds are retained, these are all in the materials, and many can be found in the database.

After Bai Ye researched this drug, his level could be improved a lot, at least for these two drugs, Bai Ye could eat it thoroughly!

After eating a medicine, you can eat all over the world, Bai Ye's mentor Master Zhang Xuewen has a nickname called Zhang Danshen, because he has a very high grasp of Danshen, not only from the perspective of traditional Chinese medicine, including modern medical research, and so on, he has his own unique views.

There is a saying: If a person is a person, he should do one line of work, one line of work, one line of work, one line of work.

If it doesn't work, do one line of work, one line of work, one line of work, no line, no line.

The same is true for medicines, if you do a good job of one drug, you can do it well if you go to other drugs.

So Liu Lao just let Bai Ye have a good start.

…………

Bai Ye has a temperament in his bones, if he wants to do it, he has to do the best, if the experiment doesn't work once, he will do it twice, and he will not stop until he gets the experimental results of the drug.

A week later, Bai Ye found that he had spent more than 20,000 yuan on medicine, which he never expected.

But fortunately, the Dongshan Animal Breeding Base has completely ceased operation, and when Bai Ye was about to pay the rent two days ago, Meng Yunxi suddenly told him that he didn't have to pay the rent this month, because a company was ready to take over, and the two sides were negotiating, everything was going well, so Bai Ye could finish what he was doing as soon as possible.

There was nothing wrong with Bai Ye's side, the two sides met, and the contract was terminated.

After the contract was terminated, the knife that was pressed on Bai Ye's head finally loosened a little, but he didn't expect that this was just the beginning, and it cost so much money just to buy medicine for his own experiments.

Bai Ye thought of the reagents he had used in the past two days, and he still felt that he should have an explanation with the school......

After all, there are more than 20,000 drugs, and this reagent is indispensable, right?

Thinking of this, Bai Ye suddenly felt that scientific research work was really an extremely expensive thing.

It's still the easiest work I do, just separation and extraction, and I didn't conduct experiments, so I spent so much money, if I started researching again......

Bai Ye suddenly didn't dare to think about it, scientific research without money as a guarantee is nonsense!

But let's talk about it after the fact, let's wait for the results of the experiment, so I started to study it again.

Every night, Bai Ye watched the experience of the separation and extraction skills that were constantly rising up, which was also a faint happiness......

It's been another three days, Bai Ye is already a little anxious, it's already mid-June, and everyone has started the carnival and nostalgia before graduation one after another, and Bai Ye is still trying and repeating.

Although no new substances have been discovered, Bai Ye's grasp of these two drugs is already very proficient, and even the separation and extraction have already arrived: LV4: 1024/30000.

But now Bai Ye is also pessimistic, if he can really make a new discovery, he would have been discovered a long time ago, and he is already very satisfied with this step.

It can be said that he now has a high degree of grasp of these two drugs and the preparations of Danshen notoginseng on the market.

No, that's the end of it?

Write a report on all the research at this stage? Anyway, the progress of the research is already very good.

During this time, Bai Ye also took out the "Traditional Chinese Medicine Processing Experience and Grade Classification" that he got by lottery to read.

However, Salvia notoginseng is too mature a drug, and there is not much difference between what is recorded above and now, the only difference is the difference in processing experience.

In this case, since it has nothing to do with concoction, then ...... What happens if you add quinoa?

The eighteen anti-anti of traditional Chinese medicine are all known, and all ginseng and peony are anti-quinoa!

Ginseng and quinoa will be toxic to drugs, compatibility contraindications, Bai Ye suddenly thought, since he can't find anything new, can he add quinoa and see what the reaction is?

Thinking of this, Bai Ye first inquired about the information, the information is there, and many people have done this experiment, but no one really explores how the reaction occurs, only that it will aggravate the neurotoxic effect of veratrol.

Bai Ye felt that this was an opportunity, and since he couldn't find something new, he simply went to create one.

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Three days later, Bai Ye looked at the substance on the chromatograph in surprise, a little dumbfounded, did it really come out?

Bai Ye reacted with the quinoa extract of many common substances in ginseng, and found that there was no effect at all.

So he tried to add another substance, which is also an extract of salvia, a substance called nortanshinon-3, but after putting it in, he was surprised to find that there was a reaction!

This nortanshinon-3 acts as a catalyst, catalyzing a series of reactions between the two extracts.

Bai Ye was stunned and found out!

However, when Bai Ye added this noradandone-3 to ginseng, Codonopsis, Panax notoginseng and other extracts to react with quinoa, there was no change at all.

What does that mean?

Specific catalysts!

Specific enzymes!

Bai Ye suddenly felt his head confused, and hurriedly began to inquire about the clinical research and experimental observation of nortanshinon-3, this substance does exist, but it is rarely done catalyst experiments, but this substance is often tested in the clinic, because the content in salvia is very small, and it can only be manifested when it reacts with veratrol.

What's the point of this thing?

This time, when Bai Ye added norshinon-3 and danshensu alone to decoction together, he found an abnormal change, noritanone-3 and danshenin were gone!

It should have gotten a new substance!

Bai Ye didn't know much about pharmacy in the first place, he looked up books and began to frantically search for information, and even missed the dinner before graduation.

After checking the information and doing research and analysis, Bai Ye found a problem, and he couldn't do the next work.

What to do?

Cooperate!

A person's energy is too limited, so Bai Ye found Zhou Mao, and after Zhou Mao learned the news, he stood up suddenly, got up and followed Bai Ye out.

In the laboratory, the two stayed up all night, and Zhou Mao suddenly looked at Bai Ye with a solemn face, and said:

"Do animal experiments, observe indicators!"

There are too many instruments and equipment needed to do animal experiments, and the current laboratory is completely incompatible, but Zhou Mao is the dean of the School of Chinese Medicine, and this right is still there.

Scientific research is always wasted.

Two weeks later, in the laboratory, Zhou Mao and Bai Ye met and smiled!

The results are out, when these two substances are shared, a new substance can be produced, and this substance effectively increases the activity of antioxidant enzymes and reduces free radicals!

What does this mean?

Quite simply, when these two drugs are combined, they will not improve blood circulation, dilate coronary blood vessels, and will not affect blood clotting function.

It has only one simple and not simple effect: scavenging oxygen radicals.

What are oxygen radicals, which are the products of oxidation that the human body produces every day after metabolism, and these substances are produced in other situations: such as stress, smoking, radiation, exposure to pollutants......

Once there are too many oxygen free radicals in the body, it will damage the cell membrane, making the cells lose stability and cannot work properly.

For example, it affects the secretion of hormones, conducts electrolytes and physiological signals, etc., and even causes some chronic diseases, which can also lead to DNA damage, causing tumors, cardiovascular diseases or apoptosis.

What is the end result?

Accelerates aging.

Therefore, it is now believed that regular use of antioxidant supplements can neutralize the damaging power of this oxygen radical and protect cells from oxidative damage, achieving a delayed aging process.

As early as 1996, a study showed that tanshinone contained in Danshen injection can scavenge oxygen free radicals caused by myocardial infarction and protect myocardial cells from damage.

The Department of Pharmacology of the Faculty of Medicine of the National University of Singapore also uses scientific methods to study the efficacy of salvia as a western medicine, and has found that after the oxidase activity is determined, salvia helps to improve the activity of antioxidant enzymes and reduce free radicals.

But no one found out why!

Bai Ye and Zhou Mao looked at each other, and finally got the result!

Zhou Mao looked at Bai Ye, and a smile appeared on his haggard face: "You...... What a genius!"

After getting along in the past few days, the relationship between the two is getting better and better, and it is not just the relationship between teachers and students.

Bai Ye smiled, scratched his hair, and made a mess, he glanced at Zhou Mao: "Uncle Zhou, you can change cars!"

Zhou Mao listened: "Bastard boy! haha...... Yes, change cars!"