In the next few days, Bai Ye was immersed in the laboratory all day long, and Bai Ye had a reference for the study of salvia and notoginseng.

Because these two drugs are actually used a lot, they have long gone through the stage of modern research in clinical practice.

Of course, the medicinal properties of traditional Chinese medicine are too complex, and there are too many compounds in it, and it is really a very difficult and cumbersome process to find out all of them.

It has to go through continuous separation and extraction, and then various processes to separate all the components of the drug, and then analyze the specific molecules.

The production method of Danqi Blood Activating Pill is very simple, after Bai Ye bought Danshen and Panax notoginseng from the market, after processing and processing, Bai Ye did not make pills, but made a decoction.

Because pill analysis is not convenient, it is better to use decoction for analysis.

Bai Ye configured the decoction according to the method written in those materials, and then continuously added the medicine to it, and then distilled and extracted it to obtain some water-soluble substances......

However, Bai Ye found a very important problem, that is, after the two traditional Chinese medicines were added, their original chemical structure would be changed, and a chemical reaction would occur to obtain new substances. This will undoubtedly increase the difficulty of extraction.

So Bai Ye extracted separately, first made salvia, he crushed the salvia into coarse powder, added ethanol to heat and reflux to extract three times, filtered, combined the filtrate, recovered ethanol under reduced pressure, and concentrated into a thick paste with a relative density of 1.30~1.35, and then heated to 80 °C with hot water......

This is a cumbersome process, but the harvest is great, Bai Ye looked at the sample he got: orange-red crystals, this should be the so-called cryptotanshione, Bai Ye took his alumina ......

In fact, the extraction and separation of traditional Chinese medicine is a very important and critical channel for the modernization of traditional Chinese medicine.

It is of great significance to explore and study the active ingredients in traditional Chinese medicine to discover active substances with novel structures or new mechanisms, so as to find new drugs with high efficiency and low toxicity.

Therefore, after Bai Ye's research in the past few days, he found that Liu Lao's purpose should be this, to cultivate his own way of thinking, as for the two drugs of salvia and notoginseng, to really separate and extract?

Both of these drugs are old-fashioned things, many people have studied them, the technology is very perfect, as long as you follow the process step by step, you can get the results.

Bai Ye basically spent the past few days in the laboratory and library and in the office of Zhou Mao, the dean of the Department of Chinese Medicine.

When Bai Ye encountered a problem, he went to the library to check it, but if he couldn't solve it, he checked it on the Internet, and finally consulted Zhou Mao.

Zhou Mao is not a doctor, he is a graduate student of Beijing Pharmaceutical University, and after graduation, he has been a teacher here, and has done a lot of projects, he and Zhang Hanlin are two kinds of people, although they are also doing scientific research in the school, but for him, the school is a platform, a platform to serve themselves.

As the dean of the School of Pharmacy, he has maintained long-term cooperative relations with many pharmaceutical companies, such as Zhennan Pharmaceutical, and often helps them do some drug research, such as drug composition analysis, drug toxicity identification, etc.

Bai Ye also got to know him a little bit in recent days, this is an economically minded scientific research worker, it is said that he has set up a small studio outside to undertake such outsourcing projects, and many of his graduate students have followed him directly after graduation.

He also sold some of his studio's small discoveries to patent applications to those pharmaceutical companies, and it can be said that he was the first person in Jinxi University of Traditional Chinese Medicine to drive a car of more than 500,000 yuan openly.

These are what others say, but Zhou Mao does not deny it, he openly admits that he does something.

But these do not affect his work, and on the contrary, many graduates every year are jobs and units that Zhou Mao helps to contact, so he is still very popular in the graduate student circle of the School of Chinese Materia Medica.

During this period of time, Bai Ye and he are relatively familiar with each other, and Zhou Mao is also very level, his professionalism is just very solid, in his words, what is the ability? It is your guy's business, if you don't even have this, what else do you have?

I have to say that economic construction as the center can indeed stimulate the development of science and technology, let's say Zhou Mao, he is the person who won the provincial progress award twice, but the patent was sold by him, and the money was used to buy a Lu Xun drove into the campus.

Originally, it caused a lot of jokes at the time, but the next year, Zhou Mao sold a patent again, this time for more money than last time.

However, Zhou Mao was very patient with Bai Ye's advice, and told Bai Ye a lot of things, salvia and notoginseng, Zhou Mao also did extraction and separation, so he was very proficient.

personally taught Bai Ye by word and deed in the laboratory, and told Bai Ye some precautions and things that need to be paid attention to.

Especially what is easy to miss and pull down, in Zhou Mao's words, that is, if you follow the path taken by others, you can only get the results of others, but if you follow the path of different people, there may be different results.

And invention and creation are to discover subtle differences, starting from the details.

Bai Ye has basically been a library except for the laboratory in the past few days, but he has gained a lot! Especially under the condition of ten times the experience bonus, Bai Ye's skills have been directly improved.

Basic Discipline Skills: Medicinal Chemistry: LV3: 2300/10000.

Scientific Skill: Separation and Extraction: Lv3: 6999/10000.

The improvement of separation and extraction skills has made Bai Ye's speed in doing separation and extraction work significantly faster.

He followed Zhou Mao's methods and ideas, and according to the ideas and methods of different people, to do the extraction work from multiple angles.

However, the two traditional Chinese medicines of salvia and notoginseng are too common, and people have also studied them badly, so after Bai Ye tried many times, there was still no receipt, except for the separation and extraction skills that had been further improved, and when he reached lv4 level, there was still no receipt.

So, Bai Ye decided not to study the two drugs separately, and decided to combine them, and try the substances after the reaction of the two drugs to see if he could get something different.

Two days later, Bai Ye was already able to isolate some common substances according to some of the techniques and instruments he had learned in these days, and the compatibility of salvia and notoginseng was very common, but it was not uncommon for people to analyze it.

For example, compound Danshen Dripping Pill is a medicine made of Panax notoginseng and Danshen extract, and he mainly uses Danshensu and Panax notoginseng saponins. This drug has been widely used in China, South Korea, Russia and other places for the treatment of coronary heart disease, cerebral thrombosis, etc.

After Bai Ye extracted those substances, he suddenly had an idea, since they only used salshensu and notoginseng saponins, were other substances useless?

Perhaps from the perspective of compound Danshen Dripping Pills, we can reverse the study of Danqi Huoxue Pill.

So, Bai Ye went directly to the pharmacy to buy this drug, and then began to analyze it.

Compound Danshen Dripping Pill is widely used in clinical practice, and the most important thing is its safety and drug toxicity analysis, which has no problem in a large number of clinical trials.

Then Bai Ye suddenly understood something.

Mr. Liu's purpose is not to let himself study this mature product, but to let himself compare the mature compound Danshen Dripping Pill through the study of Danqi Huoxue Pill, and then understand what the idea of the modern development of Chinese medicine is.

For example, Danqi Huoxue Pill is just a Chinese medicine prescription, while Compound Danshen Dripping Pill is a drug that can be commonly popular in foreign markets.

Where is the gap between them, is it obvious that they are extracting the effective ingredients and then proving their effectiveness through experiments?

The advantage of compound salvia dripping pills is to take its essence and remove its dross, so as to achieve a more mature modern product!

Bai Ye was suddenly curious, opened the history of the development of compound Danshen Dripping Pills, and was surprised to find that his mentor, Academician Liu Boli, was actually the person in charge of this topic, and he was the first prize of the National Science and Technology Progress Award in 2003.

Bai Ye took a deep breath, I see, if it wasn't for his mistake, he probably wouldn't have discovered the teacher's intentions.

But...... Bai Ye also has a new research direction.

Since the compound salvia dripping pill is to remove those dross and take out one of the essences, then if I go the opposite way, do it in reverse thinking, find out those dross, and really discover the reason why he was removed, will there be new discoveries?

Discovering something that is beneficial to mankind is progress, it is an invention, but if something harmful is invented and people avoid it, it is also a kind of progress! Moreover, many poisonous things are increasingly being found to have new effects.

Thinking of this, Bai Ye started his own action!