Chapter 172: Applying for a Lab
Bai Ye took out the paper and opening report given to him by his supervisor at that time: "Clinical Observation of Danqi Huoxue Pill on Coronary Heart Disease".
Danqi Huoxue Pill is an empirical prescription commonly used by Liu Lao to treat coronary heart disease, and after so many years of clinical efficacy observation, it is ready to be made into a finished medicine.
There is a detailed introduction to Danqi Huoxue Pill in the paper, but in fact, the recipe is very simple, only Danshen and Panax notoginseng are two flavors of traditional Chinese medicine.
However, a lot of experiments have been done, clinical observations have also been made, and animal experiments have also been done, which are very detailed.
Including the pharmacology and toxicology of drugs, a part of the research has also been done, in fact, it is a relatively complete drug research.
However, drugs are not others, and all the ingredients must be figured out, and then each ingredient must be analyzed to prove the effect on the human body, and even pharmacokinetics and pharmacokinetics must be thoroughly studied, and it may be marketed in foreign markets after several clinical trials.
Of course, what Senior Sister Bai Ye is doing is just her own doctoral project, it is a learning process, not to apply for a patent to be listed or anything, as long as it is made into a finished medicine, it is estimated that it will only be sold in the hospital, and it should not go to the market.
Not to mention her, even a large company does not have a single Chinese patent medicine listed abroad, so Bai Ye's work is actually a process of training and learning for him by Liu Boli.
However, although Liu Boli didn't take it seriously, Bai Ye still cared about it, this was the first assessment of himself by his mentor, and Bai Ye still wanted to do it well.
After Bai Ye read it carefully, he collected the medicinal ingredients and modern pharmacological research of salvia and notoginseng on the Internet.
Bai Ye has a foundation in pharmacology, and the skill level already has LV4: 12012/30000, but what is needed to analyze a drug specifically is not pharmacology, but chemistry.
For a whole day, Bai Ye searched the database in the dormitory and downloaded the papers on the modern research of salvia and notoginseng.
It's just that looking at so many chemical formulas, Bai Ye suddenly felt a little big, this large pile of various substances requires many steps to separate, for example, in the organic compound molecules, some have few hydrophilic groups, large polarity and are sparse to oil, and some have few hydrophilic groups, small polarity and are sparse to water. There are also salting out methods and so on.
Moreover, there are various physical methods for extraction and separation, such as fractionation and adsorption.
Bai Ye doesn't have a lot of research on pharmacy, but Bai Ye had an idea, this time it's June, and there are still classes in the School of Chinese Materia Medica, thinking of this, he got up and called the fat man and asked him to send a copy of the curriculum of the school's pharmacy major.
The fat man was very fast, and it didn't take long to send a class schedule.
The main courses of pharmacy include chemistry and pharmacy, and the main disciplines are organic chemistry, medicinal chemistry, biochemistry, physical chemistry, etc.
Bai Ye doesn't need to study all of them, but there are some key subjects that are still necessary to study.
Thinking of this, Bai Ye decided to skip class!
…………
Now that it's the exam month, it's the month of counting attendance and key points, after Bai Ye went, there were a lot of people, and the back row was full, leaving a few empty seats in the first row.
Bai Ye was helpless and found an opportunity to sit down in the first row.
Today's talk is about medicinal chemistry, which is a new discipline that has been added since 2011, which studies drugs from the molecular level and analyzes the relationship between the chemical structure and physical and chemical properties of drugs.
Bai Ye listened very carefully, although he didn't have a textbook, he never stopped taking notes in his hand.
However, after two or three days, Bai Ye found that this knowledge was not enough at all, and the most important thing was that the pertinence was not strong enough, so in desperation, Bai Ye went to the library to find books to study by himself.
In this way, you can learn in a targeted manner, and it may be more efficient to find a teacher after encountering problems.
If you simply consider the major you want to study, in fact, pharmaceutical analysis is more suitable, which is a sub-discipline of analytical chemistry.
In two days, after Bai Ye checked and read some books, he still felt a little cloudy, and he felt like he was in a fog.
So Bai Ye found Zhang Hanlin, hoping to apply for a laboratory and learn while experimenting, maybe the opportunity is greater, after all, this is a more experimental discipline.
Zhang Hanlin is basically obedient to Bai Ye now, and now he is the mascot of the school, so he happily agreed, and directly called the dean of the School of Chinese Medicine to ask Bai Ye to come to him.
As soon as the dean of the School of Chinese Materia Medica heard that Bai Ye was coming, he happily closed his mouth and received Bai Ye in person.
Now no one in the entire university of Chinese medicine knows Bai Ye, this is a mascot cornucopia, just in case he shows some talent in pharmacy and publishes a few top papers, or in case...... Accidentally made a major discovery!
Is it possible to apply for a country or something?
Thinking of this, Zhou Mao, dean of the School of Chinese Materia Medica, saw Bai Ye come in, and said kindly: "Come on, come on, welcome to our School of Chinese Materia Medica, that Xiao Liu, you go and pour a cup of tea for Xiao Ye." ”
Bai Ye was embarrassed and a little flattered, he was here to beg for someone, right?
Hurriedly said: "Dean Zhou, don't be busy, this time you came to ask for something." ”
Zhou Mao looked at Bai Ye with a crooked smile: "Come on, sit down and talk slowly." Do you need Uncle Zhou's help with anything?"
"That's right, Dean Zhou, the graduate supervisor I applied for, Academician Liu Boli, he gave me a small task to conduct a research on the drug composition of a Danqi Huoxue Pill. I have been reading the book for the past two days, and I always feel that I am not in the way, so I hope to apply for a laboratory in the School of Pharmacy with Dean Zhou, and I can do experimental research in person. ”
Zhou Mao listened to Bai Ye's words and nodded, it is estimated that this is an assessment or exercise of Liu Lao to Bai Ye, after all, after the clinic, there is not much contact with experiments, if you develop a more rigorous and mature scientific research attitude and ideas, it will undoubtedly be a good thing for future development, thinking of this, he also became serious: "Xiao Ye, how much do you know about pharmacy?"
Bai Ye shook his head: "I only have a little research on clinical pharmacy, but I am not very good at specific drug analysis, so I took a few classes and read a few books in our college two days ago." ”
After listening to this, Zhou Mao pondered for a while and said: "Well, in fact, pharmacy is a relatively comprehensive discipline, so let's give you a laboratory, you go to get some reagents from Mr. Yang in the equipment room to facilitate your experiments, and you can come to me directly if you have any questions during the period." ”
Bai Ye's face was overjoyed, and he hurriedly got up and thanked: "Thank you, Teacher Zhou!"
Zhou Mao waved his hand and said with a smile: "You're welcome, the materials and reagents are not enough, just ask, I'll give you a approval, do it well, when it's done, show me first, I'll check it for you, otherwise when I get to Liu Lao, I also said that my University of Traditional Chinese Medicine is delaying talents, haha." ”