Chapter 1: The Decisive Battle Against the Virus

"What's going on with Phantom Moon?" Xu Wu asked on the phone, and after listening to the first sentence after receiving the call, he said to Sister Xing that there was something at home, and she would go back first and run home.

The last time Phantom Moon called him like this, it was when the rabbit population had dropped dramatically. Is this the case again now?

"There's good news and bad news, which one do you want to hear, Lord?" said Phantom Moon was not in a hurry now.

"Let's hear the bad news first. Xu Wu seemed to be affected by the phantom moon, slowed down his running pace slightly, and listened more carefully to the voice on his mobile phone.

"The bad news is that there are multiple viral infections on the islands, with 2,203 animals already dead and 30,220 infected. The virus is still spreading. ”

"What! How can there be a virus! I've never been involved. By the way, those five people are the so-called adventure events. Xu Wu suddenly woke up, there was only one possibility, the sudden increase in variables on the island.

Xu Wu's footsteps sped up again, exerting all his strength, leaving all the surrounding buildings behind.

He could imagine what was going on the island, and the ashes were still on his bookshelf. The horror of being infected by the virus carried by humans without antibodies in the body, what happened in Guigen's body before, if it were repeated on the island, would be terrible.

There are no antibiotics or antiviral drugs on the island, but there are some natural medicines, but as I don't understand Chinese medicine, it is difficult for me to match the drugs and prescribe the right medicine.

Even if I really understood the theory of Chinese medicine, would these infected animals not be able to cooperate with me in taking medicine? I had to think of a better way to treat the creatures on the island.

But the most important thing now is to stop the virus from spreading and prevent it from spreading.

The voice continued to come from the phone: "The good news is that because there are creatures of all families on the island, reward the island owner with a pterodactyl egg." Please keep up the good work. ”

"Pterodactyl?drink...... Are there any extinct creatures?" asked Xu Wu as he ran.

It's almost there, almost home. Xu Wu, who was panting, looked at the door of his house just a hundred meters away, and kept urging his somewhat sore thighs to move forward. If you get home a second earlier, you'll be six minutes ahead of you to deal with things on the island.

The way the virus reproduces is not to divide into two or four like mitosis, but to rely on the replication of nucleic acids, one into hundreds, and one hundred into ten thousand.

Don't say six minutes, even a second, Xu Wu doesn't want to give it.

"Actually, I think the island owner has a misunderstanding about the game, for the game itself, it doesn't really matter whether it is extinct or not, as long as the genetic creature can be found on the earth, the island can reproduce it. When Phantom Moon said this, Xu Wu had already turned off his mobile phone, because he had already arrived home.

Quickly opened the door of the house, ran back to his room, and shouted directly: "Phantom Moon, teleport." ”

"Yes, my lord. Phantom Moon bowed slightly, and then a large blue light enveloped Xu Wu, Xu Wu's figure gradually blurred, his clothes were quickly tattered visible to the naked eye, and soon he landed naked on the island.

Xu Wu inhaled heavily, a chill poured into his chest, and for a moment he only felt that his body didn't seem to be so tired.

Looking around, I found myself in a halfway up the mountain, with a large pine forest behind me, and a huge rock under my feet, somewhat smooth by the wind and rain.

Looking ahead, not far away is a small stream, winding towards the base of the mountain.

"Map!"

Xu Wu, who summoned the map, found that he was on the northeast mountain, and the straight line was not very far from the grassland epidemic area where the incident occurred, probably only an arm's length away from himβ€”calculated on the map.

However, no matter how far away it was, as long as he was not directly teleported to the grassland on the island, it would be impossible for him to rush over in time, and it would make no difference.

He walked under the tree behind him and tried to find some shelter, but found that it was either a small banyan leaf, or an even finer pine leaf, and he couldn't find even patches of bark. I had no choice but to sit on the rocks with my bare butt and start giving orders.

"Phantom Moon, mark the infected animals on the map. ”

The first thing is to find out what kind of animal is infected.

A red dot appeared on the map, from the northwest to the entire grassland in a fan-shaped distribution, the closer to the northwest, the more dense, what made Xu Wu even more panicked was that there had been individual cases of infection in the forest, and there seemed to be a case of infection in the farthest southeast, which may have been brought by some flying animals.

After finding all the infected cases, Xu Wu needed to know how the viruses were infected.

"Phantom Moon, what viruses are raging on the island?"

The phantom moon appeared beside Xu Wu, and he didn't control Xu Wu's new clothes, and said happily: "According to my analysis, what is raging on the island today is a contagious influenza A virus, and the main symptoms are acute high fever, body aches, significant fatigue and respiratory symptoms. Transmission is through airborne droplets, contact and bodily fluids. The first patient was a female human who landed on the island. ”

"Flu? How can the flu in humans spread to other creatures? I see, this cheetah is a feline, right? And this is a horse, this is a big difference from the human species, isn't it? The number of chromosomes is different. And actually infected sparrows? This is human flu, right? It's not bird flu, how can it spread so easily across species?" Xu Wu was puzzled, as far as he knew, viruses generally had corresponding host types, just like avian flu rarely infected people.

Phantom Moon shook her head and denied: "Island Master, what you said is right, but influenza A is easy to mutate, don't you have many subtypes such as H1N1 and H3N2 in your history? Do you see the squirrel looking at your naked squirrel over there? The white fur, probably you haven't seen it in this species? It's all a recent mutation. ”

"So is it the virus that mutates beyond the species limit? Damn, how can so many mutations mutate in this direction. Xu Wu called out helplessly.

Genetic variation is not necessarily all good things, but more about breaking the otherwise useful and meaningful sequences, resulting in bad results.

But thinking about these things didn't help, and now Xu Wu can only find a way to stop the spread of the virus and control the epidemic within the original scope first.

Clicking on the sporadic cases, Xu Wu said: "Adjust!"

A sparrow that landed on a cherry blossom tree in the Flower Plains was subdued, and its body climbed upward, and the surrounding scenery seemed to stop the passage of time.

Xu Wu clicked on the gene bank and said with some reluctance: "The apoptosis gene is activated." Adjusted. ”

As soon as the words fell, the sparrow fell back into the tree, still surrounded by green leaves, and not far away there was a flock of butterflies flying around a large field of orchids and moons.

But after a while, the sparrow only felt that his heart was a little disordered, and the heart that had been beating all the time, the heart that maintained its physical activity, had a trace of pain, as if it was striking at it.

A minute later, the sparrow fell from the tree, and the cause of death was heart failure.

"Adjust!", "Adjust!"...... A series of commands were given, and the scattered red dots on the map all disappeared without a trace.

Xu Wu didn't want to do this, but he didn't dare to let these creatures with viruses move around and bloom in all directions, he didn't dare to imagine at all.

As for using the power of the Phantom Moon to directly regulate the immune system?

Time continued to pass, and when Xu Wu and Phantom Moon communicated, there were more than a dozen more infected creatures.

How to isolate it? It became a huge problem in front of Xu Wu.

These are not people, and they can't listen to him and stay in a certain place obediently. Even if you are human, it is probably difficult to stay in one place for a long time.

Not letting them move is not a big problem for territorial hunters, they have their own hunting range, and they don't usually run around much. But wandering creatures who have no fixed place to live are a big problem.

However, if you think about it carefully, you will find that there are not many creatures of this kind, and even if they are migratory animals, they will not make a big migration for a while.

So there's no need to quarantine, he can't do it anyway, and it's really important to think about what he can do.

So what can he do? All he can do is genetically modify, and only genetically modify.

What genes can be intervened to block the spread of the virus?

The virus itself may be able to change the sequence of the virus so that it loses its ability to replicate. No, no, this is not the right idea, one virus loses replication does not affect other viruses, it just kills one virus.

It should be adjusted to affect the virus.

By the way, some people have tried to control the reproduction of mosquitoes by releasing some sterilized mosquitoes into the wild. (Neutered mosquitoes are treated male mosquitoes that do not produce eggs that do not develop after mating with females.) This reduces the rate at which mosquitoes reproduce.

In the same way, it seems that the virus can also be modified to let it secrete some components to interfere with the replication or transmission of the virus while infecting the host. As long as the virus spreads and replicates, the spread of the flu can be stopped.

What else can be done?

The effects of antiviral drugs are mainly aimed at different programs in the viral replication cycle, and maybe I can refer to it.

Xu Wu recalled what he had learned before and continued to think.

With the five processes of adsorption, penetration, uncoating, nucleic acid and protein synthesis, assembly and release, what steps can he intervene in through genetic adjustment?

"Phantom Moon, give me a list of all the antiviral drugs that are available on the market now, as well as the reasons for their miracles and the ingredients in those creatures. ”

Penetration and uncoating inhibitors – amantadine, amantadine, enfvirdi, maraviro

DNA polymerase inhibitors – acyclovir, ganciclovir, valacyclovir, famciclovir, foscarnet

Reverse transcriptase inhibitors - nucleosides - lamivudine, zidovudine, emtricitabine, tenofovir, adefovir disoproxil, non-nucleosides - efaviren, nevirapine

......

Xu Wu looked at such a list of drugs and clicked on some of them.

Amantadine, production method: obtained by reaction with urea after adamantane bromination. Pass

......

Interferon: An antiviral glycoprotein produced by body cells after viral infection. You can try this

Xu Wu initiated another adjustment, this time targeting an infected horse on the grassland.

Just as he was about to adjust, Phantom Moon suddenly said: "The interferon in this horse's body has already begun to be expressed, and it is not recommended that the island owner interfere." ”

"Ah, what should I do!" Xu Wu was a little at a loss, in fact, even if Phantom Moon didn't say anything, he knew that such adjustments would not help at all, and he didn't have enough resources or energy to do these things that needed to be constantly regulated.

The idea of increasing the amount of interferon in the body is not feasible in the first place.

"Bump!" the pine tree made a muffled noise, and it was kicked by Xu Wu, and it shook to both sides, dropping a few pine cones down.

The surrounding woods were startled by the sudden sound, and the birds, the squirrels, fled in all directions.

Xu Wu took a deep breath and leaned on the fresh air around him to calm himself down.

Anger is the behavior of the incompetent, and he has to think calmly about the solution.

It would be nice if there was a circle of organisms around the infected area that would be immune to the flu, so that it would not spread. How can we activate the immune system of organisms in advance to make them immune to this virus?

His head suddenly seemed to explode, Xu Wu patted his head and exclaimed, "That's right, vaccine!"