At lunchtime, Grace came to Yang Rui with a plate, sat down, and asked, "Is there anyone here?" Pen & Fun & Pavilion www.biquge.info"

"No, no, Miss Grace is welcome. Huang Mao, who was at the same table, hurriedly got up and said, "I just have something to ......."

"Sit down, I'd like to have a chat with you. Grace sat Huang Mao down with a look of her eyes.

Huang Mao was inexplicably affected, and obediently returned to the position just now.

Tu Xian and Wang Xiaoyun, who originally wanted to leave, also looked at Grace curiously.

"I want to join your experimental group, is that okay?" Grace didn't have any foreplay at all, and directly inserted Yang Rui, just like her previous style.

Yang Rui put down his chopsticks in surprise and said, "You mean Huarui Laboratory?"

"That's right. ”

"I'm afraid I can't pay your salary, and Sinovel Labs can't afford to pay too much for research. Yang Rui thought for a moment and said slowly.

Although Grace often works for non-profit organizations, she is also a professor at Cambridge, and she earns more than $30,000 a year in either job.

In fact, a professor at the University of Cambridge would earn more than $100,000 if he taught both the department and the college.

However, Sinovel Lab currently does not absorb foreign researchers, and simply pays Grace tens of thousands of dollars, which Yang Rui thinks is not very appropriate.

On top of that, Sinovel Labs can't afford to join a scholar like Grace for the time being.

Salary aside, after any laboratory recruits cattle, the first thing to be prescribed should be research funds.

Yang Rui didn't know exactly what Grace's ability was, but with the general level of Cambridge professors, it was normal to spend a million dollars a year on experiments.

If it is an ion channel laboratory, it is barely reasonable to spend millions of dollars a year to recruit a Cambridge professor and wait for the award, but Huarui laboratory is not a real non-profit laboratory, and Yang Rui consciously can't suppress the joining of a scholar with a special personality like Grace.

Grace naturally thought about such a question, and said, "What is the annual salary you can afford? How about I take the same salary as a Chinese scholar and accompany you to complete the project of removing ferrite?"

As soon as Grace said this, Yang Rui's chopsticks were unstable: "You don't want research funds?"

"I just want to help you make deferiprone quickly, as long as I am doing the deferiprone project, I can use the research funds of deferiprone to do relevant research. ”

"The current salary in China is very low, just over $100 a month. Yang Rui is not scaring Grace, Huang Mao and others currently have the highest salary in the laboratory, that is, more than 1,000 yuan, and they get overtime pay, that is, 3,000 yuan at most, converted into US dollars, which is usually less than 500, of course, the official price is more than that, but normal people cannot exchange the official price for US dollars.

Grace thought of this and said calmly: "I can live with my savings." My life is not demanding. ”

"I believe in you, but ......"

"Salary is not an issue. Grace said, "I just hope that ferrite will be available soon, and I believe that with your ability, you will be able to do it." ”

Grace felt very good about Yang Rui.

She felt that Yang Rui was the purest researcher she had ever met.

Developing a new drug is not an easy task, and it is never cheap, with an average full development cost of $100 million, or a half-way development cost of $10 million, which is beyond normal philanthropy.

Grace had not heard of a philanthropist, or charitable organization, who would spend his entire fortune developing a cure for a disease that did not make money.

All drug development projects are profit-led by pharmaceutical companies, and even if they are charitable organizations set up for a certain disease, all they can do is urge and negotiate, and they are not able to lead drug development.

As an important member of Sinovel Company, Yang Rui personally executed this work, which can be understood not only because of his excellent technical level, but also because he is the person in charge of the project.

Grace couldn't imagine how many quarrels and arguments were needed, and how strong persuasion was needed for Yang Rui to make Sinovel resolutely devote itself to the research of deferitone.

No matter what it is, it makes Grace admire it very much.

Yang Rui didn't know what Grace was thinking, thought about it, and said, "I can't guarantee anything......"

"I don't need your guarantee......"

"I can't guarantee that ferriprone will be on the market, nor can I guarantee what step it will be able to do, and I can't guarantee the price of ferriprone after it is listed, or even whether it will continue to be completed in our hands, you know? This is a very risky project, and ultimately it will be attributed to capital. Yang Rui said very carefully and practically. He has the ability to complete preclinical research at a lower cost, which accounts for more than one-third of the new drug research, but for capital, this is only the first step in a long journey.

Not to mention the Phase I and Phase II clinical trials, which block 90% of the drugs from being marketed, the extremely high cost of Phase III alone can block the ambitions of any small pharmaceutical company. Each time there is as little as two or three hundred, and as many as 1,000 people in the third phase of clinical trials, after doing eight or nine times, the cost is often quite hundreds of millions of dollars, and that's it, the FDA may not be able to pass the review.

Outside of the U.S., the cost of clinical trials is also not low, and the cost of public relations may be even higher......

The development of new drugs is a bottomless pit, and Yang Rui is now involved in it, which can already be called ambitious.

The future of deferiprone is likely to be sold to big pharma companies after better data is available, as is the case with all small pharma research processes.

This is the operating rule of the pharmaceutical system, small biotechnology companies conduct research on one or two targets and do preclinical research, large biotechnology companies conduct research on multiple targets and still do preclinical research, and small pharmaceutical companies acquire biotech companies' target research while doing biological target research, and carry out preliminary compound synthesis and clinical research, but in the end, almost all drugs that want to be marketed have to go through the hands of large pharmaceutical companies.

In Europe and the United States, such a system is unbreakable, only excellent capital can change the operating attitude, in addition, no matter how strong the scholar can only be like a well-known director in the Hollywood system, participate in the film, but can not dominate the film, no matter how strong the biotechnology company can only be like a production company, produce films, but can not distribute films, with the ability to operate the whole process, all-round profits, only large pharmaceutical companies, just like Hollywood's large distribution companies.

Grace groaned for a few seconds, then said again, "I believe in you." ”

Yang Rui was surprised and couldn't help asking, "Why do you believe me?"

"In your ability, if it was to make money, you could have chosen other drugs, but you chose to deferione. Grace smiled and said, "Like I said, you're a good scholar, but you're a fighter first......"

"Fighter, I really can't talk about it. ”

"Maybe you don't know, but you are indeed charging against this rotten medical system, you may fail, most of you will fail, with your cleverness, you probably expected it, but you still stood up and ran, like Don Quixote. Grace's voice was not high, and only the people at the table could barely hear her.

Yang Rui raised his head, and suddenly, he was a little unsure of his thoughts, perhaps, there was really some element in his subconscious, which was restless and restless.

However, after a few seconds, Yang Rui put down this idea and said, "Our goal is just to make deferiprone and complete the relevant research as fully as possible, that's all." ”

"I understand, so, did I join?" Grace had a look on her face that believed you, and her eyes stared at Yang Rui even more directly.

Yang Rui hesitated for a moment and said, "You can't get any income except for your salary." ”

"I do. ”

"Okay, we should also get into animal testing, are you willing to do it?"

"Animal experiments? Grace noticed Yang Rui's expression, smiled, and said, "Don't worry, I'm not a hypocritical environmentalist." ”

……