Yang Rui's genetic engineering lab reopened. Pen × fun × Pavilion www. ｂｉｑｕｇｅ。 ｉｎｆｏ

This time, Haidian District prepared a grand ceremony for him and invited many guests.

Yang Rui is not against this ceremony, the so-called meteorological update, he also needs everyone, mainly partners, to know that the situation has changed.

An application-oriented laboratory is different from a laboratory that does basic research. Generally speaking, the more profitable the lab, the more external support it needs, such as the genetic engineering lab, when you use mice and rabbits for experiments, you can keep them in the basement or yard at your own expense, and when you use cows as a laboratory, it is unlikely to be on your own.

If the area is larger, such as breeding of improved varieties, it is not possible for a pasture to complete. Fifty years ago, the British and the Japanese were conducting similar research around the world with the help of a nation.

For Yang Rui's genetic engineering laboratory, large donations, as well as the sale of technical products, are still indispensable.

In contrast, the ion channel laboratory is much simpler, in addition to the difficulty of applying for funding, when it comes to spending money, the basic laboratory is still relatively simple.

Of course, it's not a bad thing that an applied lab needs external support. The diversification of resources always makes it easier to develop application-oriented laboratories.

In fact, the replacement of application-oriented laboratories is very fast. This also means that its resource consumption is very large, and if it can't be positioned correctly, it will soon be unable to circulate.

The North China Institute of Animal Products is a clear example of this, which relies on national resources to make application-oriented laboratories, and once weaned, they are immediately unable to hold on.

Although Yang Rui has seen many similar examples in the textbook, his personal experience is still quite deep, and he can't help but smile on his face when he sees Director Mei and others of China Animal Husbandry Corporation.

In the eyes of Director Mei and others, this is a sign of enthusiasm.

Thinking about Yang Rui, shooting a wild boar while talking and laughing, and being so enthusiastic about dealing with people, the future is really limitless...... Director Mei thought while holding Yang Rui's hand tightly, shaking it up and down, and said: "It's good that Director Yang is back, all of us in China Animal Husbandry Corporation support Director Yang." ”

Yang Rui smiled even brighter, but said: "Director Mei said this, I am relieved, our genetic engineering laboratory has resumed research work, and when the 1,000 acres of pasture are in place, all kinds of research elements will be lived." ”

When they met, they said 1,000 acres of pasture? Director Mei was stunned, Yang Rui let go of his hand with a smile and beckoned others to go.

"This guy ......" Director Mei looked at Yang Rui's back with a smile and said, "The laboratory has just been brought back, and I can't do it." ”

"Then do you want to give it or not?" Chief Tie stood in the shadows, his inverted triangle stout figure like a superhero.

When Director Mei saw his old classmates, his expression suddenly returned to his student days, his eyebrows were not eyebrows, and his eyes were not eyes......

"You don't even have the qualifications to vote, what do you say you've done all these years? "Director Tie from Qingmu spares no effort to satirize his old classmates.

Director Mei said "hey" from Beijing and Beijing, but when he wanted to continue, he wisely shut up and said: "The results made by the genetic engineering laboratory are not shared by all units? Why don't you say that you will take 1,000 acres of pasture?"

"If Yang Rui moves the laboratory to my site, let alone 1,000 acres, I can get 10,000 acres. ”

"That's your ranch isn't worth anything. Director Mei snorted twice and said, "Every inch of land in the capital is expensive, do you know?"

"It's like you're herding cattle in Tiananmen Square. Director Tie pouted: "Aren't you herding cattle?"

……

Yang Rui greeted the guests unconsciously.

It is said that it is "we", mainly cadres of Haidian District and the municipal party committee and government. A laboratory, upside down, is still a laboratory, that is, an incident with Lu Shou, the Haidian District Government, whether it is to express apologies or to express attention, many people came, and they also took the trouble to re-sign with Yang Rui.

The main content of the contract is to hire Yang Rui to be fully responsible for the work of the Haidian District Genetic Engineering Laboratory, because there is no need to prepare for Yang Rui, such a contract is very easy to sign.

The contract period was set at 10 years, but Yang Rui didn't care.

At his current level, in fact, it is more important to practice internal skills and brush out external skills.

Internal strength is research and management ability, and external strength is to brush your face and reputation.

A simple laboratory, whether it is worth millions or tens of millions, in the final analysis, needs researchers to operate, and China in the 80s was certainly short of money, but in fact it was even more lacking in people.

For example, the Haidian District Genetic Engineering Laboratory can attract Li Xingzhou and Lu Shou to intervene, and it is Yang Rui who has made the results, which is the role of internal strength. And Yang Rui can have the opportunity to play internal skills, which is made by the donations of various companies, and what the companies see is Yang Rui's external skills.

Otherwise, if we only rely on the appropriation of Haidian District itself, it is estimated that it will not be able to achieve results in the 21st century.

Of course, if someone else comes to you, even if you have sufficient funds, you may not be able to do it to what extent.

This is the synergistic effect of internal and external strength.

What Yang Rui cares more about now is the process of researching the results, as well as the results derived from the results.

On the other day, no matter which laboratory he goes to, or continues to control the genetic engineering laboratory, everyone also looks at the process and achievements.

The process is to see if he can repeat his results, and the results are to see whether the research direction he chooses is valuable.

The genetic engineering laboratory itself is actually part of Yang Rui's achievements.

If 1,000 acres of pasture falls on the head of the genetic engineering laboratory, after a few decades, if Yang Rui still masters the genetic engineering laboratory, this is naturally an important resource, that is, he does not master the genetic engineering laboratory, which can also be regarded as his achievement, which not only shows his vision, but also can brighten his resume, just like the previous heads of the Cavendish laboratory, whether it is a sequential retiree, or a change of door, when people see them, they will still take out the Cavendish laboratory at that time for reference。

Compared with the curiosity of government officials and cadres of state-owned enterprises, the researchers in the laboratory are excited.

The genetic engineering laboratory has been closed for a long time, and everyone is even ready for the laboratory to go yellow, and now, so many people are attending the ceremony of the reopening of the laboratory, but the researchers have taken a reassuring pill.

After a few hours of ushering in, everyone quickly entered the state of scientific research.

Yang Rui is even more so.

He didn't expect to rely on Qiao Gong's "appreciation" for a lifetime, not to mention that Qiao Gong's "appreciation" was originally aimed at his academic ability.

Yang Rui didn't even take the opportunity of hunting wild boars to force donations, because he knew that as long as he made results in his laboratory, donations would only continue to flow, and he didn't need to force them at all.

"Gu Qiang, you use a microscalpel to directly segment the embryos. Ouyang Shi, you have a new project here, and we will strive to overcome the embryo sex identification technology in the near future. Yang Rui did not stand in the laboratory to hold a mobilization meeting like a leader, and his mobilization was to directly assign tasks.

Although there were a few weeks out of the experiment, the researchers in the 80s were very conscious, everyone was trying to grab time, and conducting theoretical research was a very familiar job.

Gu Qiang immediately agreed and asked, "Do you want to determine the segmentation method as a microscalpel direct segmentation method?"

"I think this method has the most potential, what do you think?" Yang Rui clearly knew that this method was the most efficient, but discussion was inevitable.

Gu Qiang thought for a while and said, "If you want me to choose, I think the freehand division method is the best." ”

"Oh? Why?"

"Although the success rate is worse than that of the microscalpel segmentation method, the equipment requirements are low, and the cost is not high if you want to expand in the future. Gu Qiang said very clearly.

Yang Rui smiled and said, "You also know how to control costs." ”

"In the past few days, I have read a lot of information. Gu Qiang was a little proud.

"But you haven't thought about how much a Simmental cow embryo costs?" Yang Rui did not copy the research data, he also did in-depth thinking, at this time descriptively: "Mouse embryos, we want as much as we want, Simmental cattle embryos are to be purchased with foreign exchange, at the beginning there may be how many quantities, no matter how low the cost of equipment for freehand segmentation, which do you think China Animal Husbandry Corporation will choose?"

"With more training, the success rate of manual segmentation is at most 5 percentage points lower than that of the microscalpel method. Gu Qiang reluctantly argued.

Yang Rui smiled and said, "I believe that your success rate can be so high, I want to find you two students, how long will it take for you to mention their success rate to this data?"

Gu Qiang laughed twice: "This depends on talent." ”

He is an experimental genius, and not everyone is an experimental genius.

However, Yang Rui's answer satisfied Gu Qiang's vanity, so he silently responded.

"The task of embryo segmentation is left to you, and you not only have to practice it yourself, but also form a document to ensure that after a certain period of training, other technicians can achieve a similar success rate. Yang Rui said and looked at Ouyang Shi.

Gu Qiang was a little anxious, and hurriedly spoke: "I listened to you talk to them, didn't you say that the embryo division work should be completed in our laboratory?"

"Of course, our lab will do it, but you don't have to do it. Otherwise, are you going to do embryo segmentation in the next few years?" Yang Rui's expression was a little serious.

Gu Qiang shook his head again and again, this kind of work is done once or twice, and it will be miserable to do it as a daily work.

Yang Rui nodded and said, "You have to sum up your experience, it's best to break down the steps, so that the technicians I recruit later can learn it, this is an important job to liberate yourself." ”

Gu Qiang's expression was solemn. He was quite willing to study embryo segmentation techniques, but it made me shudder to think about it if he had to follow the established steps for several years.

Yang Rui said to Ouyang Shi again: "Gender identification technology is the focus of our next period of time, and I will do it with you." ”

"Okay, which method do you want to try first?" Ouyang Shi's expression was solemn. The gender identification technology of embryos is not as simple as a B-ultrasound in the hospital to see if there is ***.

If you want to use B-ultrasound to see the appearance characteristics, it will take at least four months for humans, even if you look at the gestational sac through B-ultrasound, it will take 6 weeks, that is, 40 to 50 days.

Obviously, such a long time is not only inefficient but also meaningless for cattle embryo transfer. The technique of determining the sex of cattle embryos is used to select males and females. For example, when beef cattle are needed, bulls are usually chosen, but if you want to expand the size of the herd, you choose cows, and if you wait until a few weeks to make a difference, the cost of sex selection is too high.

Therefore, the sex identification technology of cattle embryos does not use ultrasound at all, because the requirement is not months, not weeks, but the number of embryonic cells as the boundary.

In terms of commercialization, the maximum embryo that ranchers and researchers can tolerate is 8 cells!

In other words, when the embryo of a cow divides from a fertilized egg into two, two into four, and four into eight, it is the last window to determine the sex.

8 cells, a small state that is not visible to the naked eye, it is necessary to distinguish between male and female, and this difficulty is no longer something that can be guessed by the divine doctor.

However, biologically, many detection methods have been developed. Earlier ones include cytogenetic analysis, differential analysis of embryonic development rate, male-specific antigen detection, and so on.

Although there are many methods, none of them is easy and pleasant for the 85-year-old Chinese laboratory, and Ouyang Shi's solemn expression also comes from this.

Yang Rui is the best at doing this kind of multiple-choice question, patted Ouyang Shi with a smile, and said, "Let's try the X chromosome association enzyme assay first, and the Y chromosome-specific DNA probe." ”

"Well, why?"

"Because these two technologies are developed on the basis of PCR technology. Yang Rui pointed to himself and said with a smile: "It's not me who blows, PCR technology, I'm very familiar with it." ”

The atmosphere that had just become a little serious suddenly became cheerful.

Ouyang Shi couldn't suppress his surging admiration, and suddenly shouted: "Long live Director Yang! Long live!"

Although everyone else looked at him with surprised expressions, Comrade Ouyang Shi didn't care at all.

"Hooray!"

"Hooray!"

"Hooray!"

In the genetic engineering laboratory, Ouyang Shi's lonely and surging voice is filled.

…… (To be continued.) )