In order to decide whether to continue to do PCR, Dean Zha organized five project teams and discussed frequently for two days. Pen ~ fun ~ pavilion www.biquge.info

On the last day, everyone came to the conclusion that "do".

This conclusion is not actually unexpected by anyone.

Or rather, what everyone is looking forward to is such an outcome.

Speaking of which, including Zhang Leshan and Director Zhao, the leaders and members of all five project teams are also very confident and promising middle-aged and elderly researchers, and in the scientific research circles of the third world, everyone is also regarded as a figure in their respective fields.

It is true that everyone points to Yang Rui's PCR mixed international influence, but this does not mean that without Yang Rui, everyone has no confidence to do research.

Who hasn't done a scientific research project to fill the gap in China?

Whether it's reverse engineering or repeated experiments, being a researcher or a professor is a skilled worker.

"Without Yang Rui, we are just redoing the PCR, I think this is okay, it can help our people understand the PCR, and it will help to study the next generation of PCR. Lao Li always speaks from a strategic position and is good at finding a theoretical fulcrum, which is also an important experience experienced by people who have come from the turbulent era.

Zhang Leshan agreed: "Sharpening knives does not mistake woodcutters, and we do PCR ourselves, which can also play a role in training the team." ”

Their goal was originally to let Yang Rui teach directly, and then skip the PCR stage and go directly to the second-generation PCR.

Now, in the case that no one can repeat the experiment of the first generation of PCR, the second generation of PCR has become a castle in the air, and it can only be done one by one.

"In that case, you'll have to increase the cost. "What Director Zhao has in mind is different from Zhang Leshan and others, but the goal is the same.

Not everyone is full of achievements, such as Director Zhao, he loves money.

For those who do scientific research, the best way to embezzle scientific research funds is to do scientific research, and to make scientific research for achievements.

It's the same SCI, others spend an average of 20,000 yuan, and you spend 40,000 yuan, and the leader just doesn't investigate, and he will take a look at you.

Therefore, if you want to embezzle funds, you have to use 10,000 yuan to publish SCI and then report 18,000 funds - the embezzled funds mentioned here are indeed taking the funds to your own home, which is different from embezzling funds for research.

Ordinary scholars are more generous in terms of misappropriation of funds, and there is less psychological burden in overreporting and overpaying, but when it comes to getting money and going home, they often have to find some good projects and big projects to do.

For example, Director Zhao, he fell in love with PCR.

As for the others, even if they don't want to embezzle funds, they need funds to conduct experiments.

And the only one who can decide on the funding is Dean Cha.

Everyone's eyes were on Dean Cha.

Dean Zha said with great pressure: "On the dean's side, I am cutting the project and cutting the budget every day, and the PCR project is only launched under special circumstances, and the 800,000 yuan of funding that was said to be good will increase in a blink of an eye, which is hard to say." ”

"Dean Cha, if you can find Yang Rui, I don't think you need 800,000, maybe 500,000 can copy the PCR, but now it's not like you can't find anyone. ”

"Redoing PCR is not a trivial matter...... On the U.S. side, how is the contact?" Dean Cha still hasn't finalized.

"The Americans still have no problem cooperating with the second-generation PCR, but they are only willing to contribute to the research funds of the second-generation PCR. ”

"How much?"

"I didn't say it over there, but it's good to talk about. Speaking of this, Zhang Leshan said quite excitedly: "I listen to the Americans, as long as we are willing to give them a certain share, they are willing to pay at least a few million." Zhang Leshan paused and said, "Dollars!"

Not only Dean Cha, but the eyes of several people lit up. For researchers at the Chinese Academy of Sciences, tens of millions of yuan are quite attractive, but they are also often seen. A few million dollars is different, if it all goes to the project team, it is not only rare, it is almost like a new job.

Director Zhao said with some unease: "When Sinovel Labs did PCR, it was said to have spent tens of millions of dollars. ”

"That's also cost-effective, besides, we now have a research direction, materials and articles, and it is impossible to spend more than him. Zhang Leshan said that it is still very reasonable, PCR is difficult to do in creativity, aside from creativity, the difficulty of PCR is not high, in contrast, the difficulty of heat-resistant polymerase is higher - of course, such an analysis is required by the world's first-class standards

The former Stem company, the original author of the PCR, had two Nobel Prize winners, and it took the company more than a year to complete the PCR.

The most difficult part of the experiment is that the small parts are difficult to grasp, and the data is often biased because of the small parts.

The most troublesome thing is that the tiny parts are often not visible to you from the literature.

Yang Rui also spent several months because of this, before that, he did a lot of preparations, and did quite targeted exercises, it can be said that when repeating the PCR technique, Yang Rui's speed is already very fast.

However, the work in the laboratory has always been overlooked.

Yang Rui's hard work did not fall in the eyes of Zhang Leshan and others, they only knew that Yang Rui had spent a few months, and they took it for granted that they had many people and instruments, and if they redid an experiment, they would definitely do it better and faster than Yang Rui.

The self-confidence of several project team leaders affected Dean Cha, who finally made up his mind and said, "You go to make a budget, and I will go to the dean and say that no matter what, I want to keep the funds of the Americans." Also, it's important to hurry. ”

"Yang Rui took half a year to make it, our five groups of cooperation, two or three months can have eyebrows, when the time comes, as long as you eat the PCR, the second generation is estimated to be a little interesting. When Director Zhao heard about the funds and budget, he immediately became stronger.

Zhang Leshan coughed and said, "What do we say about the share issue that the Americans said?"

"How much do they want?"

"I don't talk about it, listen to them, the more shares they give, the more money they are willing to pay. ”

"It's not impossible to sell to them, you just follow the vitamin C scheme. Dean Cha paused for a moment, and then said: "It is best to earn foreign exchange through exports." ”

The two-step production of vitamin C is a world-class invention of China's biological industry. To put it simply, it is the previous vitamin tablets, the cost of one piece is a few dollars, the two-step method made by the Chinese to produce vitamin C, in a fully synthetic, and cheap way of full synthesis, instantly reduce the cost of vitamin tablets to a few cents, not the cost of a few cents, but the cost of 100 tablets a few cents.

Before the reinvention of vitamin C in China's health care industry and the distinction between plant vitamin C, mineral vitamin C or natural vitamin C, the two-step production of pure impurity-free vitamin C scared several pharmaceutical giants, especially Roche Pharmaceutical, into a cold sweat.

This is not a Chinese-style romance novel, but the ending is Chinese-style romance novel-style.

Through various means, Roche pharmaceutical and other companies bought all the patents and methods for the production of vitamin C by the two-step method, and then they did not put it into production, but did not hesitate to hide it, and continued to use backward production technology to produce expensive vitamin C tablets, and continue to enjoy the dividends of this billion-level market until the patent for the two-step production of vitamin C expired.

However, for research institutions like the Chinese Academy of Sciences, it is rare for them to have the opportunity to earn foreign exchange through exports.

The two-step technology of producing vitamin C can sell for millions of dollars, and in their eyes, it is almost foamy white, and so far, Roche has not shown any intention of hiding the patent.

From Dean Cha's point of view, such a selling method is naturally very cost-effective.

Zhang Leshan also thought so, and said confidently: "I will have a good talk with them and strive to create value for the hospital."

In fact, everyone is so confident that no one cares what the real structure of PCR's patent ownership is, and the few people present have no such concept at all, and they think more about the value of the technology itself.

A group of people returned excitedly and began to desperately make a high budget.

Whether it's for meritorious service or for the beloved banknotes, everyone's goal direction is still the same.

The Americans across the ocean are also excited.

After DuPont gave up the appeal, the property rights of the PCR have been very clear, and I heard that the Chinese side is willing to cooperate in the development of the second-generation PCR, and is willing to release part of the equity, and several private companies that have found the news through the Ministry of Energy are very positive.

Darbeko, an adviser to the Ministry of Energy, was also surprised to show efficient judgment, and the Ministry of Energy paid for the cooperation with the Chinese side. However, Darbeko, who is familiar with Yang Rui, still tried to contact Yang Rui while paying money.

At the same time, the Ministry of Energy and private companies have also appointed lawyers to go to China, and the equity or other things naturally need to be signed by the patentee, which is a necessary process before the money is paid.