Drawing with certain constraints is a training that has been done since junior high school. Pen, fun, pavilion www. biquge。 info

Of course, junior high schools in China.

According to the domestic teaching model, the most important point of junior high school geometry problems is to draw pictures, no matter what the topic is, as long as students can draw pictures according to the requirements of the topic, most of the problems can be solved.

The transmembrane conformation of G protein-coupled receptors is actually the same, but it is a little more complicated, or rather, much more complex.

There are hundreds of restrictions, all of which have been accumulated over the years by biology researchers. In the field of G protein-coupled receptors, the completion of a certain stage of the project in a planned scale is something that only the top laboratories can do, but outside the top laboratories, there are always some small and medium-sized laboratories that are trying to make a living, and they can't complete big projects, so they do some small projects and complete some small tests.

For example, a lab can test the relationship between a certain enzyme and a certain G protein-coupled receptor, and they don't even have to thoroughly discuss the relationship between the two, and they can do something about it.

But if they're doing the right thing, that's the constraint to consider.

The human eye cannot see the G protein-coupled receptor, just as the human eye cannot see the quark, nor can the movement of the quantum be seen by direct observation.

On the one hand, Yang Rui collected the published data of various countries and arranged special personnel to check and analyze them, and on the other hand, he readjusted the division of labor in the laboratory and liberated Su Xiankai and Gu Qiang from the heavy production of bovine rhodopsin protein - the innovation part is over, and the rest is the arduous and excellent production process, which naturally belongs to the work of scientific research dogs.

Researchers, including Su Xiankai and Gu Qiang, need to expend more energy to provide Yang Rui with a variety of data in the heavy, arduous, repetitive and innovative substrate analysis work.

Yang Rui has actually already got the answer, and if the reward is as long as the answer, he can easily get it.

It's a pity that the real world is as cruel as "one lesson, one practice" and "winter vacation homework".

The description of "process (omitted)" is so cruel in the eyes of students, and it is also a serious problem for Yang Rui.

He has to make up the process by himself, and children who have done math problems know that if you can make the process without other help, the answer behind can only play a reference role.

Fortunately, this is not a problem that he has to make up all on his own.

Compared with Yang Rui, who has full confidence, the pressure on Gu Qiang and others is much greater.

They don't know how close they are to success, they don't know if there are any competitors in the market, and they can't even be sure if they're wrong.

Fortunately, Yang Rui divided the research project into very small pieces, and everyone was in charge of their own affairs, as long as they did their own thing, all thanks to this, the atmosphere of suspicion in the laboratory did not expand.

Despite this, the atmosphere in the laboratory is still getting weirder.

Gu Qiang washes the test tubes three times a day, three each time. He would wash them for a long time until each tube had reached the standard "water does not hang on the wall" level.

Su Xiankai changes his white coat every day, of course, not for the sake of love, he only puts on his lucky white coat at some important moments, such as running glue, centrifuge, and column.

Professor Man Hai is a more traditional Chinese who is quite strict with his students on weekdays, but after entering the ion channel laboratory, everyone gradually found that his preference for red clothing grew, first red socks, then red belts and red autumn pants, and then extended to red sweaters, coats and shoes, as for the deeper red, no one wants to explore.

Yang Rui looked very helpless, and was even more worried that everyone was too nervous, which reduced the sharpness of their thinking - at this time, the researchers, like the junior high school students, were nervous and sensitive, and the pressure was so heavy that they were self-indulgent, and it was inevitable to focus on the immediate and difficult to pay attention to the surroundings.

Even in the face of the college entrance examination, Yang Rui is more recommended to reduce pressure, and if the goal is scientific research results, it is even more so.

It's just that the old men in their thirties and forties are obviously not fans of language stress relief, no matter how much Yang Rui says at the weekly meeting, no one can listen to it, and even the food Dafa that has been tried and tested cannot play a role at this time.

Although the shiny braised pork made in the kitchen was eaten up like a whirlwind, everyone's eating speed was obviously much faster than before, and they all looked thoughtful.

This state is too familiar to Yang Rui.

"I think so, after everyone has completed their tasks every day, let's rest early, and don't fight for an hour or two. As the integrity of the conformation gradually improved, Yang Rui once again proposed a new scheme.

In the past, he supervised the work of the researchers, whether it was the 110-hour program or various commendation programs, but it was like driving, you couldn't press the gas pedal all the time, and you had to brake a little when the speed was too fast.

The researchers, accustomed to the express mode, ignored him.

Gu Qiang said even more arrogantly: "If I go to sleep, the progress of the laboratory will fall, there is no need." ”

Yang Rui wanted to say that sleeping alone does not affect the progress of the laboratory, but looking at Gu Qiang's raised small chin, Yang Rui felt that it still didn't stimulate him.

"Actually, I already have a well-established protocol for the transmembrane conformation of G protein-coupled receptors. Yang Rui decided to be more realistic, and said: "We are now far ahead of foreign scholars, but we don't need to be too anxious." ”

"As long as it's not done, it's not time to be happy. ”

"Yes, the lead is not fast, and the one who is still ahead of the finish line is the champion. Professor Man Hai added professionally, saying, "I have run 5,000 meters before, and the leaders often fail to win the championship. ”

"But the one who leads must change the speed. Well, you have to run fast. Tian Bing suddenly said, and he didn't know which side he was from.

Yang Rui coughed lightly twice and said, "No one is interested in my transmembrane conformation scheme?"

"Didn't you figure it out two weeks ago. Gu Qiang said tiredly: "We're not perfecting your plan now. ”

"What's the matter, dissatisfied with my plan?" Yang Rui deliberately raised his eyebrows.

Su Xiankai was afraid that Gu Qiang would talk nonsense, so he hurriedly said, "Director Yang, Gu Qiang is joking." ”

"I know he's joking, and it makes you seem to be telling the truth. Yang Rui waved his hand and said, "The atmosphere in the laboratory is too tense, I think it's okay, everyone will have a half-day rest tomorrow." ”

Although it was only a half-day break, it was also very unaccustomed to the researchers who worked all day.

Xu Zhengping stood up with some anxiety, looked around, and said: "Director Yang, if the current research direction is smooth, we want to make persistent efforts and complete some projects before resting." ”

"Don't you want to give you a holiday?" Yang Rui laughed.

"That ......" Xu Zhengping hesitated slightly, and said: "I think there is an old saying, call the stupid bird to fly first, our technical level may not be as good as foreign counterparts, we have to work harder." ”

For a moment, Yang Rui suddenly had a feeling of being educated.

"Tomorrow half a day off, you are not tired, I will be tired to death. Yang Rui waved his hand and forcibly issued the order.

From his point of view, his advantage is big enough, and compared to his ultimate goal, conformation is the first step, and he can't use up all his energy in the first stage.

……