Chapter 1183 - Try It Yourself
The tense and perpetual scientific research competition is actually non-existent, as if no matter how strong the army is, it can't keep participating in siege warfare, and it has to give them a chance to repair. Pen | fun | pavilion www. biquge。 info
The same is true for laboratories participating in the world's top scientific research competitions, although high-level laboratories have multiple groups to be able to rotate, but it is more normal to adjust slightly between competitions, or to slow down and stabilize a little when occupying a leading position.
Of course, the most common mode of rest is that of a slightly backward laboratory. There is usually only one winner in scientific research competition, so laboratories that have fallen behind many times will often make groundbreaking experiments into repeat experiments when the pursuit is hopeless, so as to reduce costs, temporarily recuperate, and wait for the next battle.
However, the risk of doing so is obvious, if you fall behind in autonomy and thus reduce the competitiveness, the initiative of the competition is in the hands of other labs.
If the leading laboratories suspend the publication of information and postpone the publication of papers, then it is not uncommon for them to unknowingly lose the second round of the scientific research competition, or even the third and fourth rounds.
This is exactly what Yang Rui hopes to do.
Nowadays, the scientific research competition on G protein-conjugated protein is in the ascendant, and all laboratories are still in a warm-up state, and Yang Rui does not want to startle the snake.
Now, too, is the only time that the ion channel lab has an advantage.
If those well-known laboratories actually have a certain understanding of each other, it is not so easy to postpone the publication of information or postpone the publication of papers, at the very least, the other party can guess your progress, and in addition, you can also understand the situation through the instruments and equipment you have purchased.
The most direct information comes from the funders, whether it is a government-invested project, a corporate consortium or a foundation, or even an individual-funded project, it is always necessary to publish some information, especially in developed countries, there is a considerable system to ensure this.
In this way, it is possible to start a project that exceeds the original project schedule requirements, whether it is additional funds or the use of surplus funds.
However, these are usually those that belong to foreign laboratories, to first-class laboratories in developed countries, and not to third world laboratories.
Even if the ion channel laboratory has to report any information to the research management department, the foreign laboratory does not care.
To this day, no "foreign friends" know that Yang Rui wants to put the big satellite of G protein-coupled receptors.
Besides, satellites are not something you can put if you want to, and before proving himself, Yang Rui deliberately ran to put satellites, which may not have any effect.
However, the researchers in the ion channel laboratory did not have the slightest suspicion.
At least in the domestic environment, Yang Rui is the most qualified candidate to be a G protein-coupled receptor.
And to say that no one in China can make G protein-coupled receptors, no one wants to listen to it, and no one believes it.
In order to prove similar negative propositions, the Chinese do not know how much effort and sweat they have put in.
In the spring of 1986, the researchers at the Ion Channel Laboratory once again felt a sense of urgency.
"Put the lid of the centrifuge on. ”
"The 50 ml test tube is not weighted? Don't you want to die? Do you know how powerful this thing is?"
"These are ultracentrifuges, and if you throw the test tubes out, they can smash through the wall and kill the two people next door. ”
Su Xiankai walked in small steps in the laboratory, tirelessly checking every step.
The first step in the G protein-coupled receptor is to produce large amounts of bovine rhodopsin protein. The production and volume here are relative to the normal laboratory scale, but in terms of steps, it is not much less than that of a factory.
The most troublesome part here is that the production of bovine rhodopsin protein requires a low-temperature ultracentrifuge before it can be used.
And the cryogenic ultracentrifuge ...... Before Yang Rui's ion channel laboratory was purchased, there was only one in the whole of Peking University.
As for now, in order to make G protein-coupled receptors, Yang Rui bought 6 units in one go, each of which cost more than 80,000 US dollars, and the most expensive one is 150,000 US dollars, which is more than the net worth of many laboratories.
If it weren't for your own money, or the ion channel laboratory's own funds, Peking University would not necessarily approve it, not to mention forcibly organizing, forcibly talking and delaying are possible, and the value of the existence of superior leaders is to suppress you with power when your three views are not in harmony.
Low-temperature ultracentrifuges are indeed needed.
Bovine rhodopsin protein is used for comparative research, it is equivalent to the basic resource of the whole experiment, and the more the quantity required, the better.
Without a large amount of bovine rhodopsin protein, Yang Rui's current project is impossible to talk about.
In fact, it was because foreign laboratories had discovered the connection between bovine rhodopsin protein and G protein-coupled receptors that Yang Rui decided to carry out this project.
This makes bovine rhodopsin protein a basic material, and the more the better, and the more you do, the more you do, the basic material will be consumed, but unfortunately, the treatment of bovine rhodopsin protein is not a basic treatment......
Su Xiankai's early task is to understand bovine rhodopsin and produce it as quickly as possible.
It's boring and necessary.
It's a bit like the production of uranium during the development of the atomic bomb.
The atomic bomb requires a large amount of uranium for both research and production, and there is no problem in saying that the atomic bomb is built on the production of uranium.
However, important is important, and this work is not easy.
Unlike standardized factory production, Su Xiankai needs to constantly adjust the parameters of various reagents, and even experimental methods, as if he is doing the real questions of the college entrance examination every day, keep doing, keep doing, and try his best to get high scores.
He seems to be doing similar topics forever, but he always makes unexpected mistakes, which makes Su Xiankai anxious.
"How's it going. In recent days, Yang Rui has also cared about Su Xiankai's work.
Su Xiankai knew why, shook his head slightly, and said: "I still need a while, the recent concentration of the solution is too low, I want to increase it a little, and then increase the speed of the centrifuge a little, and reduce the time a little......
"It's not been a while. Yang Rui patted Su Xiankai on the shoulder and said, "Let's start sending materials to Fan Zhenlong's group today." ”
"No, then how can it be done!" Su Xiankai hurriedly shook his head and said: "We have very little inventory now, Fan Zhenlong just started to do it, mistakes must be indispensable, it is a waste of time for materials, you wait for me to improve another link, accumulate a little more inventory......"
"Old Sue. Yang Rui shook his head and said: "The scientific research competition is a battlefield, and it is never possible to be fully prepared. ”
"I ......" Su Xiankai opened his mouth and said, "What if the back is broken?"
"I believe in you. Yang Rui gave such a sentence.
Because, to tell the truth, Yang Rui also didn't know how to increase the amount of bovine rhodopsin that met the requirements.
He has a way to point out the direction, but what Su Xiankai needs now is not direction, he wants specific experimental values, or even just numerical values, but more experience accumulated from experiments.
This is something that Yang Rui can't give, what he gives you is only requirements and funds.
Su Xiankai's eyes were red, he looked at Fan Zhenlong obliquely, and said, "You kid had better not waste my hard work." ”
"I try. Fan Zhenlong's honest answer made people's teeth itch.
……