"Lao Su, we don't have enough protein here. www.biquge.info"Fan Zhenlong walked around from the side of the experimental table, shouted, and then retracted his head and went away.

Su Xiankai snorted twice and complained, "Why did you run out again?"

"I can't help it, I can't do it all the time. Fan Zhenlong said in annoyance: "The amount of protein on our side is going to exceed the plan." ”

Su Xiankai's eyebrows twitched twice, and said, "I'm not sure if I can make the planned amount, you exceed the plan, what should I do?"

Fan Zhenlong said helplessly: "Of course we don't want to go beyond the plan...... It can only be said that what we thought in the early stage was too simple, and the three-dimensional structure of this thing is much more difficult than expected. ”

"It's really difficult. Gu Qiang was very reluctant to admit it, but he still said: "Our original plan may have to be completely revised......

"No need to modify it. Yang Rui himself kept scanning the literature and said, "The newly ordered equipment will arrive soon, and in addition, Lao Su, I will add two more people to you." ”

At the beginning of the plan, Yang Rui knew that he was going to overspend significantly, and he made various preparations.

took out 6 million US dollars, only to spend half of it carefully, and the rest was to be used as a reserve, besides, he still has a large amount of RMB that has not yet been used, and the funds of the ion channel laboratory, plus the allocation of the 863 plan, it is not a problem to make up 3 million yuan.

If it is not enough, he estimates that he can get another sum of money from Peking University, and theoretically, from domestic biomedical and animal husbandry central enterprises and even ministries and commissions, he can also raise a large amount of money.

This is the benefit of prestige, as long as the project is successful, these donations are taken for nothing.

As for the failure of the project, it is the prestige itself that is lost.

Yang Rui actually doesn't know how much money is needed to make the desired results, but he knows how much foreigners use, so he has a considerable estimate of the difficulty of each link.

As soon as Su Xiankai turned his head, he knew that Yang Rui had been prepared, which made him slightly embarrassed.

Yang Rui saw it, and Su Xiankai was embarrassed for a moment, and said: "The plan we made is based on the first-class foreign laboratories, and now, we have not yet reached the level of the first-class foreign laboratories, it doesn't matter, I have prepared more funds and more resources to make up for the gap between us." ”

After a pause, Yang Rui said: "G protein-coupled receptor is a world-class project, and after all, it is necessary to fight with first-class foreign laboratories with bayonets, so everyone, including me, must grow up as soon as possible." ”

As soon as he said this, Su Xiankai's expression softened.

However, the pressure of reality quickly pressed on Su Xiankai.

"Just adding two people and a batch of machines can't make up for the gap between us and first-class foreign laboratories. Su Xiankai noticed a loophole in Yang Rui's logic.

Yang Rui pursed his lips and said: "If we do a project like a first-class foreign laboratory, it will definitely not work, but our goal is to focus the material on bovine rhodopsin protein." ”

Several people in the laboratory looked at Yang Rui incomprehensibly.

Su Xiankai even asked: "Isn't our material bovine rhodopsin protein?"

"We are, but this is not necessarily the case in foreign laboratories. ”

"Why?"

"Because they want better materials, they want to try more templates, and this is our chance. Yang Rui still hasn't said a word, that is, he knows that at this stage, bovine viptosin protein is the best material.

G protein-coupled receptor, as a protein that can cross the membrane seven times, has a very complex molecular structure, and this complex molecular structure, even if it is the reason for human research, is also the reason why it hinders human research.

Bovine rhodopsin is the most stable and clear seven-transmembrane protein that scientists have found.

At least at this stage, it does.

Of course, the ambitions of scientists are limitless, and they will always want better materials.

Yang Rui also wants that when his laboratory becomes the world's top laboratory, even if it costs two or three times the cost, he will explore such a world.

In China in 1986, the Ion Channel Laboratory of Peking University was not qualified to do so.

In ordinary laboratories, it is a common practice to select one material, or in order to diversify risks, select a variety of experimental materials and carry out experiments directly.

Yang Rui gave his confidence to bovine vipplein protein, and that's it.

This kind of knowledge is a matter of course for Yang Rui, but for Su Xiankai and others, it is a little obscure. After 30 years, even if domestic graduate students do not read relevant papers, they can learn a lot of relevant information from their classmates and teachers, but in China in 86 years, there are no such conditions.

Foreign first-class laboratories do experiments, foreign top laboratories do scientific research, and domestic ordinary scholars have no concept at all.

Not to mention laboratory management, all of which are classified without confidentiality.

Yang Rui knows very well that in the field of G protein-coupled receptors, everything is chaotic, as is the case in eight or six years, and the same is true in one or six years.

It's just that, equivalent to other people, Yang Rui can see a little more information.

For example, in the chaotic field of vision, find the most appropriate material.

"I asked someone to send an extra batch of bull's eyes. Yang Rui stood up, made a phone call, said a few polite words, and hung up: "It's done, Lao Su, let's double the scale, no problem." ”

"Double?" Su Xiankai said with some discomfort: "Do you want to come step by step, and increase it by about 20% first?"

Yang Rui sighed and said, "Doubling is coming step by step." ”

He glanced at Gu Qiang and Fan Zhenlong, and said, "Don't listen to them say that it is more than double the estimate, it's true, with your current progress, I think that it is far from enough for you to provide twice as much bovine rhodopsin protein." ”

Gu Qiang was unhappy and said, "Director Yang, you look down on people." ”

Yang Rui raised his eyebrows and asked, "If you want me to look up to it, where have you gone now?"

Gu Qiang snorted for a long time and said, "We are close." ”

"If it weren't for the fact that you guys made some snacks, do you think I would add materials to you?" Yang Rui gave a sentence half of encouragement, and said: "Don't be verbose, you also have to learn a lesson, don't let Lao Su's hard work go to waste." ”

Su Xiankai's face had already collapsed, and he said: "I feel that I am similar to being a coolie, director, how can I say that I am also the deputy team leader, can't we give me a more energetic job?"

"Your work is energetic enough, in addition, our main work in the recent period is to produce bovine rhodopsin protein, so your side is the main direction of attack......

"You lied to me. Su Xiankai was full of suspicion.

Yang Rui said solemnly: "In the next month, or two months, the place where there will be a large increase in funds, materials, instruments and personnel is the production of bovine rhodopsin protein, understand?"

Su Xiankai believed it now, but frowned and asked, "Why?"

"Why? Because your teammates have a low level of experimentation, slow work, and high consumption, and don't have any other good ideas, you can only feed them with materials. ”

Yang Rui provoked one after another, and finally stirred up Gu Qiang.

Comrade Gu Qiang took the case and said: "You see, we don't have to feed it, and I will increase the success rate in the next day." ”

"Yes, I can speak Beijing dialect, and I can read it decently. Yang Rui suddenly had a smile on his face, which caught people off guard.

Gu Qiang was choked and couldn't help it, so he couldn't continue to talk about the topic of pronunciation.

Xu Zhengping coughed at this time and asked, "Yang Rui, do you really want to double the yield of bovine rhodopsin protein?"

"Yes, this is our only chance to catch up with foreign labs. Yang Rui deliberately said more seriously, and said: "We must realize the strength of the enemy, and we must not underestimate ourselves too much, the success rate of your experiments is indeed not high, but what about the researchers in foreign laboratories? How many times they can succeed? This is a big project, and there are still many experiments to follow, and it will be very long, so we need to gain an advantage from the source, so that we can eliminate the enemy's other forces, right?"

"Foreign laboratories, don't they want to improve the success rate from the source?" asked Fan Zhenlong.

"First, foreign laboratories cannot determine that the most appropriate material is bovine rhodopsin protein. Second, even if they do, they are hoping for the success of the next experiment. Third, their channels for obtaining fresh bull's eyes can't catch up with us. ”

The last one is Yang Rui's half-truth and half-hypothesis.

To a certain extent, after Yang Rui established the genetic engineering laboratory, his relationship with various animal husbandry companies was able to provide him with a large number of animal materials, which was limited to such a small point, which is the world's top condition.

Fan Zhenlong was a little stunned when he heard Yang Rui say the second point, he knew Yang Rui's speaking habits too well.

Fan Zhenlong couldn't help but ask suspiciously: "What do you mean by saying that they are pinning their hopes on the success rate of the next experiment?"

That's what it means literally. Yang Rui coughed.

"No, you say hope, you mean there should be no hope. ”

Yang Rui laughed twice and did not answer directly.

Fan Zhenlong asked again and again.

Yang Rui pondered the language and said, "Let's put it this way, it's more accidental. ”

More than just accidental, the three-dimensional structure of G protein-coupled receptors, like various star exploration programs, is completely stacked in numbers.

What quantities are piled up?

Bovine rhodopsin protein!

The top foreign laboratories, at this point, have actually ignited backwardness.

It was only when they realized that bovine rhodopsin was the best material, and only when they realized that a lot of material was needed to build up the three-dimensional structure of the G protein-coupled receptor, that they could be considered to have caught up with the progress of the ion channel laboratory.

Of course, once the top foreign laboratories realized this, they caught up extremely quickly.

Yang Rui could only run as fast as possible.

Fan Zhenlong was completely shocked by Yang Rui's answer.

He hesitated for a long time and asked, "How accidentally?"

"You can do it without worry, I will organize the production of enough materials. Yang Rui patted Fan Zhenlong's shoulder and let him relax.

Fan Zhenlong's heart is about to explode!