"No, the rancher is already ill and can no longer be vaccinated against the disease, otherwise, it will only aggravate the clinical reaction. Pen & Fun & Pavilion www.biquge.info"

Ye Zhenzhen asked: "Who is the vaccine for?"

Nan Zhiqiao glanced at Ye Zhenzhen, as well as the medical staff beside him, and said quietly, "Give it to us." ”

"Ah, for us? You mean, we have the possibility of being infected?"

Nan Zhiqiao: "Well, the disease is very contagious, we have come into contact with sick sheep and patients, and the possibility of infection is very high, so high-risk groups like us should be vaccinated in advance to prevent it." ”

A little nurse sitting at the other end of the carriage, only twenty years old, looked at Nan Zhiqiao's words, and saw Nan Zhiqiao handsome and chic, with a cold temperament, and the image of a male god in the minds of a standard girl, the little nurse asked Nan Zhiqiao with admiration: "Are you an expert in infectious diseases?"

Before Nan Zhiqiao could answer, Ye Zhenzhen pointed at Nan Zhiqiao and hurriedly said to the little nurse: "Yes, he is an expert in infectious diseases at the Chinese Center for Disease Control and Prevention, and he is very powerful, and the epidemic in the sheep ranch can be detected in time thanks to him." ”

Nan Zhiqiao glared at Ye Zhenzhen, turned to the little nurse and asked, "Is there anything wrong with you?"

The little nurse looked at Nan Zhiqiao and nodded again and again, "Well, I just graduated from nursing school this year, I have been working for less than two months, and I don't know about many diseases in the hospital, I just want to ask, does he really have cloth disease?

Nan Zhiqiao: "Judging from the clinical symptoms, he has signs of brucellosis, but to confirm the diagnosis, he has to go to the hospital for laboratory testing, but the hospital's reserve of testing capacity for zoonotic infectious diseases is generally not as good as that of the CDC, and then it is necessary to ask for help from the Municipal Center for Disease Control and Prevention." ”

The little nurse frowned, as if she was recalling something in the depths of her memory, thought for a long time, and said: "When I was studying in school before, I only saw an introduction to cloth disease in books, and the book only briefly introduced that cloth disease is a disease caused by a bacterium, and there are no more, but I didn't expect that I encountered this infectious disease today, you are an expert in this area, can you give us a detailed introduction?"

After the little nurse finished speaking, she looked at Nan Zhiqiao with an expectant expression, Nan Zhiqiao glanced at Ye Zhenzhen beside her, Ye Zhenzhen also nodded, and echoed with a smile: "I also want to listen, Senior Nan, you can tell us about it." ”

Nan Zhiqiao thought to himself, I just made a report to the experts from all over the country at the meeting today, and here I want to popularize the knowledge of infectious diseases for these little hairy children, but shouldn't this be what the teacher should look like, Nan Zhiqiao cleared his throat, sat upright, and began to explain: "Brucellosis, the full name of brucellosis, is a zoonotic infectious allergic disease caused by the invasion of bacteria of the genus Brucella, and it is a Class B infectious disease reported by the Law of the People's Republic of China on the Prevention and Treatment of Infectious Diseases.

It is a public health problem facing the whole world, especially in developing countries. However, it is only more than 100 years since people really understood the disease and continued to develop and study it in depth.

As early as 1860, Morston made a systematic description of the disease and proposed it as a clinically independent infection based on clinical features and autopsies, called 'Mediterranean flaccid fever'.

In 1887, Bruce, a British military doctor, isolated Brucella ova from the spleen of a British garrison soldier who had died of 'Maltese fever'.

In 1897, the Danish scholar Bang and the American scholar Traum in 1914 isolated the bovine breed Brucella and the porcine breed Brucella from the amniotic fluid of aborted cows and the aborted fetuses of pigs, respectively. In 1918, Evans found that in the process of studying the cultures of Brucella ovis and Brucella bovine, the two were similar in morphology and culture characteristics, and there was a cross in serum reactions. Later, after the successive research of Meyer et al., by 1920 they were classified into the same genus according to the common properties of the two, called Brucella. Diseases of humans and animals caused by bacteria of this genus are collectively referred to as 'brucellosis'. Soon after, the porcine species Brucella was also included in this genus.

Bevan in South Africa in 1921 and Keefer in 1924, as well as Viviani in Italy and Evans in North America, isolated Bovine and Porcine Brucella from patients, thus epidemiologically confirming for the first time that sick cattle and pigs are the other two sources of human disease.

In China, as early as 1905, Boone reported two cases of brucellosis in Chongqing. In 1916, a patient with cloth disease was also found in Fujian. In 1925, four Indian expatriates were found to be infected with brucella in Henan, and the sheep breed Brucella was isolated from the blood of the patients. In 1932, 1936 and 1949, Xie Shaowen reported 29 cases of brucellosis in Beijing. In 1936, 21 out of 109 cattle were found to have been aborted in Wangye Temple, Inner Mongolia, and two strains of bovine brucella were isolated from the aborted cattle fetuses. Also in 1936, the Japanese Kitano Masaji and others conducted a survey of sheep in Baichengzi, Jilin Province, and found that the infection rate reached 33%. In 1938, the Japanese Hikoyoshi Hiroki also found patients with cloth disease in Baichengzi.

After the founding of the People's Republic of China, the epidemic in most provinces and municipalities in China has occurred and prevalent to varying degrees, and the epidemic situation in China was the most serious in the fifties and sixties of the 20th century, significantly decreased in the seventies, and continued to decline after the eighties, and the epidemic situation in the mid-nineties was in an echo area, and the upward trend of the epidemic in the 21st century has become more and more serious. In recent years, the epidemic has mainly occurred in Inner Mongolia, Shanxi, Heilongjiang, Liaoning, Hebei, Shaanxi, Henan, Jilin, followed by Xinjiang, Tibet, Shandong, etc., and Gansu, Qinghai, Ningxia, Sichuan, Beijing, Tianjin, Jiangsu, Anhui, Zhejiang, Fujian, Guangdong, Guangxi and other scattered epidemics.

All provinces and autonomous regions in the country have had animal outbreaks to varying degrees. There are more than 20 kinds of domestic animals and wild animals that are prevalent in the disease, and the city of S where we are now located, because of the geographical environment and climate, has developed animal husbandry, and it is a natural epidemic area of the disease, and there have been epidemics of the disease before. ”

The medical staff in the ambulance were dumbfounded, and the eyes of the little nurse turned from the nymphomaniac worship just now to shock, but I didn't expect that the man in front of him, who was only about thirty years old, could memorize the things in the professional literature backwards, and even remembered the era and the name of the person so clearly, worthy of being an expert in the Chinese Center for Disease Control and Prevention.

Ye Zhenzhen had heard of Nan Zhiqiao's name for a long time, and had been with her in Paris for a while, and knew that Nan Zhiqiao was a young god in the biological academic world, and now she was not so surprised that Nan Zhiqiao could tell the history of the development of the disease so clearly.

Ye Zhenzhen asked: "Senior Nan, are you specialized in the study of cloth disease at the Chinese Center for Disease Control and Prevention?"