Nan Zhiqiao shook his head, "No, I've just read some literature related to cloth disease and know a little." Pen %Fun %Pavilion www.biquge.info"

Ye Zhenzhen sighed in her heart: "Nan Dashen is too modest, he can know so clearly after reading some literature, so if he specializes in research, wouldn't it be even more powerful." Ye Zhenzhen asked: "Senior Nan, have you ever had the ability to never forget?"

Nan Zhiqiao: "It's not enough to remember it, but after reading it once, you can remember it nine times out of ten." ”

Ye Zhenzhen stuck out her tongue and said in her heart, it is really a great god, a certain sage once said that genius is one percent of talent and ninety-nine percent of hard work, it seems that if you want to become a great god, this one percent of talent is very important.

The little nurse recovered from the shock and asked Nan Zhiqiao: "Teacher Nan, what are the symptoms of cloth disease? This patient in our ambulance has meningeal irritation, what other symptoms does cloth disease have? You tell me about it, so that I can also know how to distinguish patients in the future." ”

Nan Zhiqiao: "Brucellosis is a systemic disease, and people can have a variety of clinical signs and symptoms after suffering from it, but it often lacks specificity. Because these signs and symptoms can also be present in patients with other medical conditions. The disease also varies widely, with the exception of severe cases, some mild cases can only be diagnosed by bacteriological or immunobiological methods.

There is a certain incubation period from infection to the appearance of clinical symptoms, but the length of the incubation period is uncertain, which is related to the type, bacterial volume, virulence and immunity of Brucella invading the body. In general, the incubation period is 1-3 weeks, with an average of two weeks, and it has been reported that the shortest is only three days and the longest is one year.

The onset of brucellosis is acute and slow, and a small number of patients have prodromal symptoms, which are quite similar to severe colds, general malaise, fatigue, loss of appetite, muscle and large joint pain, headache, insomnia, sweating, etc. Most patients have an acute onset and no prodromal symptoms, and the onset of the disease begins with acute symptoms such as chills, fever, and sweating.

The main symptoms of brucellosis are: fever, sweating, fatigue, osteoarticular and muscle pain, headache, neuralgia, and other symptoms.

Fever is one of the most common clinical manifestations of brucellosis and can be seen in patients at all stages, ranging from one to one and a half months, with an average of two to three weeks.

The symptoms associated with fever are excessive sweating, especially in patients in the acute stage, sweating is quite severe, often soaking through clothes and pants, making patients feel nervous, irritable, and even affecting sleep, and heavy sweating can also lead to collapse.

Most patients with brucellosis have the symptom of fatigue, the degree of fatigue varies from severity to severity, although the light can be engaged in general work, but it is easy to fatigue, and it is not easy to eliminate, and the severe ones are malaise and can not be qualified for their own work, because the symptoms of fatigue are more prominent in the manifestation of the disease, so some people call the disease 'lazy disease'.

Osteoarticular and muscle pain is also the most common symptom of brucellosis and is often the main reason patients seek medical attention. In the acute phase of brucellosis, the pain is mostly migratory, similar to rheumatic fever, mainly in the large joints. Some pain is very severe, often make the patient toss and moan, and even general analgesics can not be relieved, the nature of the pain can be like a cone or intractable dull pain, the time of occurrence is mostly related to fever, often the pain is aggravated when the fever begins, and the pain is relieved when the body temperature drops in the morning. One or more significant tender points are often found near painful joints and bones. The pain in the chronic phase is generally confined to a certain part, and it is also more common in large joints, which is a persistent dull pain or soreness, and some are only a feeling of heaviness, which affects joint movement. Due to the stiffening and contracture of the tendons of the elbow fossa and popliteal fossa, the joints of the limbs are often stiffened and deformed, and even cause lifelong disability that cannot be recovered.

Headache is one of the common symptoms in the acute phase of brucellosis, and patients in the chronic phase often have headache while being fatigue and weakness. Individual patients with severe headaches often have meningeal irritation, which is typical of ranchers.

Neuralgia is mostly caused by nerve trunk or nerve root involvement, and radicular neuralgia usually occurs two to three months after the disease, and patients feel less severe pain in the lower limbs. Nerve trunk lesions mostly occur in the intercostal nerves and sciatic nerves. When the intercostal nerves are affected, the patient feels severe chest pain that worsens with breathing. In sciatica, severe pain in both lower limbs and limited movement.

Other symptoms of brucellosis in the acute phase often manifest as anorexia, diarrhoea, constipation, intractable cough, and cough up white frothy sputum. A small number of female patients may have swelling, pain and miscarriage. Patients in the chronic phase often present with depression, apathy, insomnia, irritability, irritability, chills and warmth, impotence, sperm loss, fever in hands and feet, and lack of appetite. One of the symptoms of the disease is the aggressive behavior of the rancher before he falls unconscious. ”

When the little nurse heard that the disease could cause a miscarriage of a female patient, she thought to herself, she was not married, and if she was infected, she would not leave sequelae and would not be able to have children, so she asked: "If the woman has the disease, will it affect the future fertility?"

Nan Zhiqiao continued: "Female patients with brucellosis can develop mastitis, salpingitis, oophoritis, endometritis, amenorrhea, dysmenorrhea, and excessive vaginal discharge, but it is rare to have symptoms such as miscarriage, premature birth, and infertility. ”

The little nurse frowned and asked, "Infertility symptoms are rare, that is, it is possible to produce infertility sequelae?"

Nan Zhiqiao nodded, "Well, so, try to avoid contracting cloth disease." ”

A trace of panic flashed on the little nurse's face, and Nan Zhiqiao then said: "In case of infection, as long as it is treated in time, the chance of these sequelae will be greatly reduced." ”

The little nurse breathed a sigh of relief.

Ye Zhenzhen originally thought that the disease was just a class B infectious disease, and the severity was naturally not as serious as a class A infectious disease, but when she heard Nan Zhiqiao say this about the symptoms of the disease, she was also nervous, although the fatality rate of the disease is not high, but when it is serious, it will leave people with lifelong disabilities, and women may be infertile, which is also very terrifying.

Ye Zhenzhen asked: "As long as you get the cloth disease vaccine, will you be able to avoid being infected with the disease?"

Nan Zhiqiao: "There is no vaccine that can achieve 100% preventive effect, first of all, after the vaccination of the vaccine, the body's response to the vaccine, everyone has a difference, and then, even after vaccination, the body produces antibodies, but the duration of antibodies in the body is indefinite, especially the cloth disease vaccine, at present, China uses 104M freeze-dried live vaccines, the protection of the vaccines is limited, the duration is short, inoculation of a vaccine, can protect the body for one to two years, continuous use can produce certain adverse reactions. Therefore, the use of vaccines on a large scale is not recommended, but only in the event of an outbreak or epidemic of the disease, for severely threatened groups, or in times of emergency, such as bioterrorist attacks, the vaccine can be used for vaccination. ”