Chapter 50 Mathematically

Mathematical induction, which is the generalization of infinite sequences, is a kind of confidence, but this is based on continuity

The complexity is large, and it will be biased towards the unchanging state

The relationship between internalization and externalization in complex space is approached in infinity

The inertia of the sequence, the influence exerted by the environment, will manifest itself probabilistically, but will eventually have a statistically significant distribution

The anchoring effect, the basis of cognition, we change it, we can get people to make the decisions we want, which is the contrast effect. The small contrast www.biquge.info pen, fun, and pavilion is also closed, and the internal and large contrast is vertical

The equivalence of prime numbers --- density --- distribution function of density

An even number can be formed by the addition of prime numbers, which is the connection between addition and multiplication

The whole is an unconscious statistic, like the thermal motion of gas molecules

Geometry is the limit of cognition, and the resolution of the number axis determines the space of one dimension: real numbers--- fractions--- irreducible numbers (non-cyclic numbers, transcendent numbers) - complex numbers (two-dimensional). If it is close enough to infinity, it will manifest different properties

Any sequence of rational numbers can be treated as a real number when it converges, i.e., am-an tends to 0, which is based on our cognitive limits and a solid foundation by comparison

The paradox is to understand different levels at the same time

Straight lines are not infinite but finite closed in Riemannian geometry, indicating that the geometric form of coupling is feasible

Dimensionality means that the combination is incrementally incremental, i.e., complex, and can be simplified using a certain pattern

The way out of drug research lies in group research. Consider networks, matrices, differential equations

A single active ingredient is a special solution, artemisinin in Artemisia annua, schisandrin and biphenyl diester extracted from Schisandra chinensis for the treatment of hepatitis, ginkgo biloba extract (egb) extracted from Ginkgo biloba leaf composed of a variety of ginkgo flavonoid glycosides and ginkgolides, etc., which can be regarded as a low-order approximation; a class of chemical structures are similar, similar functions, and play a synergistic role, which can be regarded as second-order, (different antagonistic components can also work together) The next step is to build a connection to form a three-dimensional structure, that is, a system. hierarchical coupling, such as reactions within the human body

Ambiguity is like a wave function, describing the overall situation, which is the overall concept

The mechanism of action, the composition of the formula, and the compatibility of the prescription are also combinations, and the important thing is the combination of differential equations with hierarchical coupling

The proportions of the components and the respective concentration ranges are a system of levers, which is a mechanistic idea, and I see it as an approximation

Classified according to polarity

The overall effect, the overall indicator, is like the correspondence of two wave functions. The interaction between the external intervention system (TCM compound) and the biological response system (the complex system of the human body).

Non-anatomical structures are the materialization of relationships between tissues

Drug resistance is that its target is fixed, biological instinct will produce resistance, and its effect is rigid, which is prone to toxic side effects

Use omics to approximate the full picture of relationships

The research should be related to the etiology, location, and pathogenesis (pathological link) of the specific disease it treats, which can be considered to be optimized by combining genetic algorithms

Extraction and efficacy screening of the effective parts of the traditional Chinese medicine compound for the treatment of vitiligo", the traditional Chinese medicine compound can be divided into flavonoids, coumarin, anthraquinones and chalcones according to the large categories of chemical components it contains. The correlation between chemical composition and efficacy was explored by using four pharmacological indexes, including insecticidal and spot removal, wind dispersion and dehumidification, nourishing essence and blood, and tonifying kidney and yang. The results showed that flavonoids had the effect of activating tyrosinase activity and increasing skin photosensitivity, coumarin had the effect of dispersing wind and dehumidifying and sensitizing the skin to ultraviolet radiation, anthraquinones had the effect of sperm and blood deficiency and skin itching, and chalcones had the effect of stasis and stagnation and dark effect of rash. Through a variety of active ingredients in 4 effective parts, such a prescription not only conforms to the regulatory effect of traditional Chinese medicine with multiple links, levels and targets, but also combines the overall biological effect of modern medicine, which can directly activate cellular immunity, enhance tyrosinase activity, improve the skin's photosensitivity to ultraviolet rays, and induce targeted migration of melanocytes (i.e., induce melanocyte growth), proliferate, develop and regenerate to promote melanin synthesis, providing the possibility for the effective site drug treatment of vitiligo diseases of this TCM compound.

Polylateral research must follow the rules of the relative pattern of square evidence

This can be calculated by the continuous decomposition of the various symptoms until they are quantized

Firstly, through a series of in vitro and in vivo metabolism studies, the common and main metabolic pathways of CYP3A-mediated hydroxylation metabolism into triol saponins in ginseng were determined[8], and then the regulatory effect of lignans, the main component of the adjuvant drug Schisandra chinensis, on intestinal and hepatic CYP3A was studied, and it was found that the short-term administration of lignans had a significant inhibitory effect on intestinal CYP3A, and significantly improved the oral bioavailability of ginsengtriol-type saponins, which partially explained the synergistic effect of the adjuvant drug Schisandra chinensis. The compatibility mechanism of improving the pharmacodynamic effect of Jun Yao ginseng. Multi-level coupling: drug metabolism enzymes, transporters, intestinal flora, protein binding

Multiple causes and effects, such as the process of drug formation, also have an impact on the properties of the drug

Take analogies, extravagant and inward, deductive reasoning--- reductive decomposition (simplify, find structure, but there is deduction) --

Holistic, endogeneous, complex, universal, extensional, dynamic, open, orderly, self-organized

Hypothesis: Individuals are free in nature, can behave in isolation, and have overall patterns, i.e., statistically significant, predictable, additive, and --------- wave functions

The leap in level, the change in scale

Complexity and degrees of freedom, which are axes of coordinates, predict changes in order (Taylor series)

Complex systems often have different scales in space, and their structure often has multiple levels, and changes in individuals within a hierarchy can affect another level

System quantization, topological identity

In the process of evolution of complex systems in different fields, universal laws are followed

Enzymes connect different levels due to their catalytic properties

Linear regression, weighted parameters

The sum of squares is the angle of the probability distribution as a function of misestimation

Diversity may not be evolutionary differentiation, but at another level is a multilinear decoupling of the wave function, coupled to genes and genes (reproductive isolation of species)

The reduction in activation energy due to the catalytic action of enzymes is a marginal effect

Planck's constant is the embodiment of the non-conservation of the universe, the difference between the two forces, which can also be regarded as a probability, and the embodiment of a sufficiently large scale is inevitable, which is also the reason for the emergence of life and evolution

The change in the structure of the enzyme may cause a great change in the scale, such as excessive force, or it can be a special solution of the wave function, and some factors such as pH value and temperature are a kind of operation

Chaperones enhance the response, competitive molecules rate limiting, which is the relationship between molecules

The maximum velocity, the pH value means the optimal solution, considering the ratio of the power ratio of the chemical equilibrium used

Physical motion, the circulation of organisms, that is, pathways, etc., the relative motion can be regarded as the construction of a space of living beings. Taking into account Einstein's theory of relativity, we seem to conclude that there is a limit similar to the speed of light, and that the rules of relative motion are equivalent to the stability of dynamic systems

The particle is the quantization of physics, and the quantization of biology is the object of the hierarchy, that is, the non-closed cycle

Displacement-combination, distance-total, velocity is the time differential of displacement, then the combined time differential is probability, acceleration is the differentiation of velocity and the substantive embodiment of space, and the time differential of probability is the probability density, which is the depiction of the world; v=wr

Force is the interaction between objects, is the cause of change, corresponding to the interaction of living things, is like the coupling cycle of waves, and moment is the cause of the state of rotation m=f*r, a vertical relationship

Unequal is approximation, the first step to understanding

First-order structure: sequence, second-order: specialized structure such as spiral turn angle (probabilistic emergence), and third-order: domain

Consciousness is the manifestation of the subconscious, which is a probabilistic behavior, but whether this is substantive or combined, I think, should be the possibility of connection between different individuals, and this network-type connection structure is bound to lead to a pattern, that is, what we call the rule: modularity and hierarchical coupling. This can be seen as a set of quants with a certain tendency, satisfying a series of physical laws, such as Boltzmann distributions and operator operations of wave functions.

Modularity seems to be an independent entity at a certain level, and we will have a sense of separation. But it is also a living and evolving individual, which makes the whole robust and resistant to certain changes, while maintaining the ability to quickly return to a new homeostasis after a drastic change. The nature of the network, from a human perspective, seems to be a bit ruthless, but is this similar to the way of heaven? It is not for the sake of survival, it is not for the sake of destruction, and the way of heaven is not benevolent, and all things are used as dogs.

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