Chapter 301 Special Drugs
In the process of human aging, the decomposition products of lipid free radicals are aldehydes, which can react with the amino groups of proteins, phosphorus and nucleic acids to cross-link molecules, and as a result of cross-linking, proteins are denatured and enzymes are inactivated. Pen, fun, pavilion www. biquge。 info
These denatured substances are engulfed by phagocytes but cannot be completely digested, resulting in an ever-increasing increase in the annual pigment within the cells.
The toxic effects of escaping the accumulation of neutralized free radicals may be the root cause of aging, so removing useless free radicals is likely to delay aging.
Of course, if the human body does not have too many useless free radicals, then free radical scavengers are useless.
However, the study of the extraction of the active substances inside the lost incense is not only for the free radical scavenger, because the active substances inside the lost incense can also improve speech, vision, hearing disorders, enhance concentration, treat rheumatic pain, strengthen liver function, lower blood sugar, help the treatment of arteriosclerosis, and help paralyzed limbs to restore mobility.
Of course, even if the active substance is not extracted, the edible value of Lost Fragrance is not small, Lost Fragrance has a strong astringent effect, regulates greasy skin, promotes blood circulation, stimulates hair regrowth, and improves hair loss.
Rosemary is a spice often used in Western cuisine, especially used in steak, potatoes and other dishes, as well as baked products, sweet with pine smell and flavor, rich fragrance, sweet with bitter taste.
It can be said that the lost incense crop has a very high economic value, of course, in order to fully exert its value, you must also have that ability.
Mo Xie has already used the cheat to get the results directly, and now it depends on whether the various active substances he has refined can work or not, and whether there are any toxic side effects.
If there are no toxic side effects, then in the next time, Mo Ye will start to reverse the extraction process and strive to achieve industrial production.
Walking into the laboratory, looking at the piles of glassware, these are the main experimental equipment in this laboratory, several other old microscopes can be used, and some other things, Mo Ye does not know and will not use, of course, they are also likely to be unusable.
At this time, the laboratory was divided into three parts by Mo Ye, one part was the breeding area, the other part was the pharmacological experimental area, and the other part was the experimental area.
The breeding area is all a variety of plants cultivated without soil, among which the lost incense is the most, and there are many other messy ones, which are all recently added by Mo Ye.
Of course, this is also because the area of this laboratory is not small, otherwise Mo Ye would not be able to grow so many plants.
There are more than a dozen mice in the pharmacology experimental area, and it is because of these mice that his laboratory will be discovered.
These mice, Mo Ye is ready to do free radical scavenger experiments, so they are more bitter, at the beginning they have to endure all kinds of waste, cigarettes, etc., and finally observe the effect of free radical scavengers.
And the last part is the main experimental area of Mo Ye, where Mo Ye mainly isolates various plants and extracts various active substances from these plants that he is more interested in.
Of course, if some more useful active substances are found again, Mo Ye will also find a way to extract some.
These extracts did not use the super biological detector to cheat, so he did not put them away, but kept them in the refrigerator in the laboratory, and those that cheated were collected into the space by Mo Ye.
Some time ago, Mo Ye's main job was to monitor the growth process of various plants, and after more than a month of observation, Mo Ye had collected enough information about the growth process of different plants, different times, and different environments.
Now, his main job is to isolate the various nutrients, or active substances, from the plants.
Lost incense couldn't understand it for a while, so in the past two days, Mo Xie put his mind on the relatively fast-growing coriander.
Coriander is also a good thing, especially to use the value, coriander is spicy, warm, to the lungs, spleen meridians; It has the effect of diaphoresis, dissipating appetite and qi, awakening the spleen and neutralization; It is mainly used to treat symptoms such as poor leakage, food stagnation, loss of appetite, and prolapse in the early stage of measles.
Originally, Mo Ye only liked its growth ability and regeneration ability, but with the in-depth study of biological knowledge and as he learned more and more about coriander, Mo Ye actually used the vegetables that are often used in it to refine several Chinese patent medicines.
At the earliest, Mo Ye discovered that the super biodetector could detect viruses and bacteria, otherwise the food found would not indicate whether it was toxic or not.
Later, he accidentally discovered the beneficial bacteria in the noble rot wine, which made Mo Ye more aware of the superiority of the super biological detector for scanning bacteria and viruses.
However, although he discovered this, Mo Xie never figured out how to use this ability, but with the completion of Mo Ye's leaky biological laboratory, Mo Xie knew how to use it.
Let's just say coriander, as long as it is paired with several other plants and treated a little, you can get drugs with various functions, and the effects that have been confirmed by traditional Chinese medicine can be studied, such as drugs for the treatment of measles.
The current traditional Chinese medicine treatment for measles is to use 3 strains of coriander and whiskers, 3 water chestnuts, 3 grams of comfrey, add half a bowl of water, fry for 15 minutes and filter the juice, take it in 2 times, take it once every 4 hours, and take it when the rash is about to appear, which can prevent complications.
Also, you can also use 500 grams of coriander, after the water is boiled, boil the coriander for 1~2 boils, and then pour the water into the basin, first with hot air fumigation, and then wash your hands with water, which can cure measles should not come out or the rash can not be penetrated.
Through these two home remedies, it is easy to know that some substances inside coriander can treat measles.
And which part of the substance is working, it is not difficult for Mo Ye to judge, because as long as the measles virus test is passed, the bioactive substances that can act on the measles virus can be accurately found.
If someone else did this, it would definitely not be easy, but for Mo Ye, it would be too easy, because the super biological detector could scan the microscopic world, and it could clearly observe the changes in the entire microscopic world.
Therefore, the development of the medicinal value of coriander is not difficult for Mo Ye at all.
Since he has such an ability, Mo Ye naturally has to work hard to tap its potential, so just around a coriander, Mo Ye has discovered several active substances, and these substances have been refined, and their medicinal value is definitely much stronger than the current Chinese patent medicine.
Coriander has many medicinal properties, such as treating stomach cold, hemorrhoids, indigestion, high blood pressure, cold and flu, and so on.
Just one coriander, Mo Ye can also develop nine kinds of medicines, the active substances extracted from coriander leaves and wine can treat stomach cold, the active substances extracted from coriander fruits, tangerine peel, Liuqu, ginger can treat indigestion, substances extracted from coriander and kudzu root can treat high blood pressure, and from coriander, caramel and rice soup can be obtained to treat colds.
It's just an ordinary vegetable, and you can refine seven or eight kinds of Chinese patent medicines by drawing on the formula of Chinese herbal medicine, what is this concept?
It is with this motivation that Mo Ye will work tirelessly to grow vegetables and do experiments in the laboratory.
Of course, although these are simple, but they are very cumbersome to do, even if Mo Ye has the help of a super biological detector, he needs to keep separating various substances, constantly testing these bioactive substances, and the effects of various viruses, which will definitely not be able to be completed in a while.
Although I know that there are many effects of coriander, Mo Ye did not start the experiment with all of them, but targeted and started the research from the simplest, because the cold virus is the easiest to collect, so Mo Ye's recent research is the Chinese patent medicine for the treatment of colds.
Although coriander, starch syrup and rice soup will form substances that kill cold viruses during the steaming process, the determination of this substance, the medicinal value, dosage, and mechanism of action need to be studied.
After all, traditional Chinese medicine has a slow effect, so it needs to be more refined, if the active substance that works can be accurately found, then can it be possible to increase the dose to improve the efficacy?
This is what Mo Xie is most interested in, because there are too few special medicines for treating colds, and the mutation of cold viruses is too fast, so today, with such advanced technology, human beings can't even cure a cold and cough, which is also an anomaly.
"The most annoying thing is clinical trials!" Looking at the bioactive substances extracted in his hands, Mo Ye sighed a little, even if he achieved this level, there would be no less trouble in the future.
Mo Ye has completed the screening of active compounds, and at this point, there are still a lot of things to do.
Of course, in fact, many laboratories are blocked by this step, because not all synthesized compounds can have ideal activity.
At this stage, it is necessary to screen out the preliminary active compounds as candidates through biological experiments, these compounds are called lead compounds, and the activity data obtained can be combined with the compound structure to obtain a preliminary structure-activity relationship analysis.
The structure-activity relationship can effectively guide the subsequent structural optimization of compounds, which is mainly carried out at the level of cell experiments.
Now Mo Xie doesn't have to be so troublesome, he can determine that the active substance screened out is an effective active substance, but even so, the next step is to evaluate the pharmacological effect, safety and toxicity of the drug, the absorption, distribution, metabolism and excretion of the drug.
This part of the experiment needs to be carried out at the animal level, and the results of cell experiments and live animal experiments can sometimes be very different.
The purpose of this step is to determine the effectiveness and safety of the drug, even if Mo Ye now knows that the drug he extracted is safe, he needs to do an experiment to make sure, because this is eaten by people, he doesn't dare to have any carelessness.
Even he himself would not dare to eat the things he extracted until he did animal experiments.