Chapter 223 Chinese Medicine Monomers
Maple Leaf Pharmaceutical Company was transferred to Ambrera Company, but people in the company had great opinions about Ling Shizhe's approach, thinking that his boss was investing indiscriminately, especially Alison and Foster had a lot of opinions on Maple Leaf Pharmaceutical. The products produced are all big road goods in the market, and there are no bright products, so its product sales are also average, although it can provide drugs for its own medicine, but with the company's annual production volume, Raccoon Hospital can't digest so much.
The Maple Leaf Company's new drug research and development capabilities are also very poor, and it can only play a little bit of patent fees, copycat the expired drugs of those large companies. But there is also a problem, you can copy, others can also copy, under the fierce market competition, the profits of drugs have also been pressed to the extreme, even if the drug wants to sell well, it all depends on the marketing methods of the company's sales staff, but the marketing methods of the Maple Leaf Company are not very good, otherwise it will not be so in a half-alive state.
In Alison and Foster's view, if Maple Leaf Pharmaceutical Company wants to change this situation, there is only one way to go, that is, to study new drugs with a market, but how can the research of new drugs be so easy, R&D funds alone are astronomical, if Ling Shizhe wants to develop new drugs, it will inevitably affect the company's other R&D projects greatly, so it is not surprising that Alison and the company have resistance to Maple Leaf.
Maple Leaf Pharmaceutical Company was also unhappy, thinking that after Ambrera bought the company, it would pay for the development of new drugs, but it waited for such a result, so the two sides fell out.
This obviously did not benefit the unity of the company, so Alison informed Ling Shizhe, who was far away in Hong Kong, hoping that he could come and deal with it himself.
The key is that Alison doesn't know what Ling Shizhe's plans for the future of this pharmaceutical company are, and he doesn't approve of Ling Shizhe's entry into the pharmaceutical field, so he doesn't want to care very much.
Seeing the fax sent by the Canadian company, Ling Shizhe smiled bitterly at Li Li: "It seems that you have to go to Canada with me, call your eldest brother too." ”
"What does this have to do with my eldest brother?" "It doesn't matter, whether the Maple Leaf Company can get out of this half-dead situation is really inseparable from your eldest brother." Ling Shizhe said with a smile.
After Li Li called Li Zhen in Taiwan/Bay with a stomach full of questions, she flew to Canada with Ling Shizhe.
"Big brother, I didn't expect you to arrive first." After Li Li walked out of the passage at Toronto Airport, she saw that Li Zhen was already in the airport hall.
Li Zhen looked at Li Li and smiled: "Not only am I here, but Uncle Qin is also here." ”
"Uncle Qin?" Li Li looked behind Li Zhen and found an old man sitting on a chair pretending to sleep, hurriedly came to the old man's side, and said happily: "Uncle Qin, you have good bones, I didn't expect that for my business, your boss would come from thousands of miles away." ”
Uncle Qin opened his eyes and looked at Li Li, and said with a smile: "Girl, I haven't congratulated you on being a mother!" I'm coming to Canada this time, and I'm not leaving, so I've decided to retire here. ”
Li Li looked at her eldest brother suspiciously, and Li Zhen smiled: "It was arranged by your husband." ”
Hearing Li Zhen say this, Li Li seemed to understand something? Qin Bo's name is Qin Junren, born in a family of traditional Chinese medicine in the capital, and his ancestors have been imperial doctors in the Ouchi for generations, specializing in treating the imperial relatives of the Manchu government.
After Emperor Xuantong stepped down, the Qin family also left the palace and left the capital, and opened a medical center in Hangzhou/Zhou. During the Anti-Japanese War, the Qin family medical hall was destroyed in the war, and Qin Bo's family was also killed by the Japanese, so in order to avenge his family, Qin Bo joined Li Chunlai's anti-Japanese army and became a military doctor with the army.
Later, the Kuomintang was defeated and retreated to Taiwan/Bay, and Qin Bo also followed Li Chun to Taiwan/Bay.
Since the ancestors of the Qin family were all imperial doctors and had a lot of secret recipes in their hands, Ling Shizhe took a fancy to this and asked Li Zhen to invite him.
Ambrera sent two cars, one for Li Zhen, Ling Shizhe and Alison, and one for Li Li, Qin Bo and Yang Shuxin, the general manager of Maple Leaf Pharmaceuticals, to drive towards the location of Maple Leaf Pharmaceuticals outside Toronto.
In the car, Li Zhen said to Ling Shizhe: "Brother-in-law, I have already invited you over, what are you going to do with Uncle Qin to your pharmaceutical company?" Let me tell you, Uncle Qin is already eighty years old, but he can't stand the toss. ”
"Don't worry, I won't let him do anything, I just asked Qin Bo to come over and be a consultant for my pharmaceutical company." Ling Shizhe explained.
Li Zhen laughed and said: "Then you will be disappointed, I know that you have taken a fancy to the prescriptions in Qin Bo's hand, but have you thought about it, these prescriptions are all traditional Chinese medicine, Europe and the United States do not recognize our traditional Chinese medicine, and it is useless for you to take it." ”
Ling Shizhe said with a smile: "Although Europe and the United States do not recognize traditional Chinese medicine, have you ever heard of a technique called the westernization of traditional Chinese medicine?" ”
Traditional Chinese medicine is different from Western medicine, Chinese medicine is taken in the form of decoction, which is the most prescribed dosage form prescribed by doctors, but often young people are more resistant, one is because it needs to be boiled, it is more troublesome, and the other is that the decoction has a stronger taste; But Western medicine is different, it is taken in the form of tablets, as long as a glass of water and medicine are swallowed, it is convenient and fast, and the effect is faster than that of traditional Chinese medicine, so Western medicine is very popular with people.
As a result, some TCM practitioners began to improve the preparation of Chinese medicine and turn it into Chinese patent medicine to make it easier for people to take it.
For a long time, traditional Chinese medicine has had "problems" such as unknowable adverse reactions and difficult control due to unclear active ingredients and low quality control standards, which has made traditional Chinese medicine and traditional Chinese medicine injections "scaled diseases". At one time, some people even thought that traditional Chinese medicine was a product of ignorance and backwardness and should be abolished. Even Lu Xun once said: "Chinese medicine is nothing but a kind of intentional or unintentional liar".
In addition, the internationalization of traditional Chinese medicine has been struggling for many years, and traditional Chinese medicine gives people a sense of decline, even in the current traditional Chinese medicine hospitals, the use rate of Western medicine is much higher than that of traditional Chinese medicine. Coupled with the prejudice against traditional Chinese medicine in Europe and the United States, traditional Chinese medicine has been slow to open the European and American markets.
In the 50s, a research technology called biopharmaceuticals emerged in the West, which allowed the majority of Chinese medicine practitioners to see a ray of light, and they began to combine traditional Chinese medicine manufacturing technology with biopharmaceutical technology, and invented a new type of biomanufacturing technology that meets the standards of Western medicine - traditional Chinese medicine Westernization technology. For example, in the 60s, Japan launched the world's first traditional Chinese medicine injection, ginkgolide injection, which successfully entered the European and American markets.
A distant relative of Mr. Ding Zhaozhong, a famous Chinese high-energy physical scientist, is also a master in the Westernization of traditional Chinese medicine, he invented the monomerization technology of traditional Chinese medicine, and also successfully entered the European and American markets of traditional Chinese medicine.
The so-called traditional Chinese medicine monomer technology is a technology that uses Western biological extraction technology to extract effective chemical ingredients from Chinese herbal raw materials to make Western medicine tablets.
In fact, the so-called Westernization technology of traditional Chinese medicine is a new type of chemical synthesis technology. Compared with traditional chemical medicines, Chinese herbal medicines contain not a single chemical component, and they are peaceful and more suitable for the human body.
For example, the monomerization of traditional Chinese medicine (i.e., the effective part of traditional Chinese medicine), such as ginkgolide, basically retains the characteristics of multiple targets of traditional Chinese medicine, synergy between components, and attenuating effects, and also basically retains the effectiveness and safety of traditional Chinese medicine.
In addition, there are three flavors in the compound Danshen Dripping Pill: Danshen, Panax notoginseng and borneol, in the past, we made compound Danshen preparations, which were directly made into medicines, ground into powder to make tablets or concentrated and processed. According to the composition of traditional Chinese medicine monomers, it is to extract the notoginseng saponins in Panax notoginseng and the danshensin in Salvia, extract the clear active ingredients in them, and then carry out pharmaceutical synthesis.
Traditional Chinese medicine monomers are very in line with the requirements of the Western pharmaceutical market, and do not contradict the principles of traditional Chinese medicine itself, and the effect is better for the treatment of a certain disease, so the traditional Chinese medicine monomer technology has been widely used in the Republic of later generations. But it is not without shortcomings, that is, although the monomer technology is in line with the Western pharmaceutical market, and also greatly improves the therapeutic effect of traditional Chinese medicine, the toxicity of traditional Chinese medicine has been amplified.
It was precisely with the monosystem medicine technology that Ling Shizhe dared to invite Qin Bo to guide him in the westernization of traditional Chinese medicine.
"What kind of monomerization technology are you talking about, can it really solve the problem that traditional Chinese medicine is not recognized by the West?" Qin Bo asked with concern, Chinese medicine has always been not recognized by the West, and it has become a heart disease in his heart, and now seeing that Chinese medicine has the possibility of being recognized by the West, his heart is warm again, which is also the reason why he agreed to Ling Shizhe to come to Canada.
Ling Shizhe patted the old man's hands, calmed the old man's excited mood, and then took out a single comparative product catalog published by the Republic of China from his briefcase and handed it to the old man.
Li Zhen took out the old man's reading glasses, Qin Bo took them and put them on, and looked at them carefully.
"Old man, does this chart work for you?" After the old man finished reading, Ling Shizhe asked.
"Where did you get this watch?"
Ling Shizhe said with a smile: "Don't ask about this, I just want to ask, with this chart, can you turn the Chinese medicine prescription you hold in your hand into a medicine recognized by Westerners." ”
"There's a big possibility." The old man thought about it and answered Ling Shizhe's words, Qin Bo studied Western medicine when he was young, and he was very clear about the context of Western medicine theory and pharmaceutical principles, so he completely understood what Ling Shizhe said about the monomer technology of traditional Chinese medicine, and now that he sees this chart, he is more confident about the westernization of traditional Chinese medicine.
"Okay, I'll do it, I'll give you all the prescriptions in my hand." The old man made a decision.
"Thank you, Uncle Qin." Ling Shizhe said happily, the ultimate purpose of his invitation to the old man this time is the various prescriptions in the old man's hand, without these prescriptions, Ling Shizhe can only study from scratch like other pharmaceutical companies, but with these prescriptions, he can skip all the previous steps and directly carry out the production of finished medicines, and soon enter the clinical trial stage, thereby saving a lot of time and research and development costs. This is the same reason that he knows the prescription of Viagra.
Therefore, Chinese medicine is a huge treasure, for thousands of years our ancestors have developed Chinese medicine prescriptions that can treat various diseases, as long as you know these prescriptions, and know the correct method of Westernization of Chinese medicine, it is difficult to make money.
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