In May 1886, four new drugs stirred up the medical profession in half of Europe.

Thanks to Mr. Nicklaus's tireless efforts, samples of aspirin were delivered to more than 600 physicians across Europe, and with the excellent results of their trials, Heinz received orders for more than 40,000 bottles throughout April.

Meanwhile, in the May issue of the journal German Medicine, three more papers were published, following the two aspirin-related papers in the previous issue, and only one from the Charlotte Hospital of the University of Berlin and the other two from the far-flung Heidelberg University Medical School.

The same is about antipyretic and analgesic, and the other is about antirheumatic effects.

In this era when people are extremely unaware of many diseases, and at the same time lack of drugs that can be treated, doctors often think more about how to relieve the patient's apparent pain, so things like Yapian, Kekayin, and even later Hailuoeyn will become popular and become one of the most common supplies in the doctor's medicine cabinet. Therefore, it is conceivable that if there is a drug that can relieve the symptoms of high fever and headache in patients, and its adverse reactions are almost negligible, it will be welcomed by doctors and patients!

In this case, aspirin naturally immediately burst into flames!

And what can be more popular than aspirin is naturally only the product of the same Heinz pharmaceutical company, three sulfonamides that have just been launched on the market!

It's hard for people in the 21st century to imagine what people endured more than 100 years ago.

Ordinary enteritis is enough to pose a great threat to humans, and fever and cough after a rain can be fatal, and in this case. Most people don't even know what the cause of these threats is - because of the tireless efforts of Pasteur and Koch, very few know that it might be caused by something like a gadget.

Therefore, the appearance of sulfonamide is like a thunderclap that resounded in the sky!

"At the end of the day, it's the end of an era and the beginning of an era!"

At his own dinner table, John explained to his grandfather why he was so careless. He said calmly: "The emergence of the three sulfonamide drugs has ended the era when people could not fight those tiny creatures head-on, and at the same time opened a new era of active confrontation with them, and for any doctor, if they want not to lag behind this era, they must take the initiative to understand and use sulfonamide drugs, which is an unavoidable future......

……

Returning to Berlin from Vienna, Johann only rested at home for two days.

Just two days later, John rushed to Heinz Pharmaceutical at the urging of the elder Huntelaar. Of course. He was sent to the company not because of business or company management, nor because of the production of four new drugs that were already on the right track, but because during the time he left Berlin for Vienna, after the cooperation of as many as thirty chemists, the method of industrial production of lidocaine and procaine finally came to fruition!

This sudden news surprised John very much!

Ever since John began his epochal appendectomy at Charlotte Hospital, neuraxial anesthesia has become the routine anesthesia for this procedure. In other areas of surgery, infiltration anesthesia is also used by surgeons. Increasingly, gas inhalation anesthesia is being replaced.

But......

The extremely low production and high price of the two local anesthetics made everyone complain, and Professor Bergman even asked John or Thomas every few days. Urging them to do their best to solve the problem of drug production and cost. You must know that although John has invented two ways to prepare local anesthetics, due to the high requirements for technical conditions, only the chemistry laboratory in the university has the ability to prepare a small amount, and the cost is even more frightening, and a local anesthetic drug alone under a surgery requires tens or even hundreds of marks!

Other words. Only those who are wealthy can enjoy safer local anesthetic drugs.

If it weren't for John's supply of local anesthetic drugs to Charlotte Hospital at cost price, and Professor Bergman's decision not to charge for them, I am afraid that there would be very few people who could afford procaine and lidocaine, and the meaning of saving zài would have been completely lost.

As a result, the Department of Chemistry at the University of Berlin and the R&D department of Heinz Pharmaceuticals have started to work together.

The University of Berlin is strong in chemistry. Naturally, there is no doubt about it, and John has always maintained a fairly close relationship with the Department of Chemistry. Originally, when the two local anesthetics were prepared, many chemists and students at the University of Berlin mastered the corresponding skills in order to make a little extra money, and with the recruitment of Ehrlich and Hoffmann by Heinz Pharmaceutical, and the recruitment of a large number of chemists, the strength suddenly became stronger.

With abundant financial support, the Department of Chemistry and Heinz Pharmaceuticals began to cooperate.

More than 10 experienced chemists and more than 20 outstanding chemistry students began a planned and organized study, and they began to look for ways to quickly and massively prepare procaine and lidocaine in factories according to the molecular formula provided by John and the corresponding preparation method in the real yàn chamber......

In just three months, Heinz Pharmaceuticals has spent more than 150,000 marks on research!

This amount is undoubtedly an astronomical amount for any chemistry of this era, considering that the annual education and research funding of the chemistry department of the University of Berlin is about the same amount, and it only took three months for Heinz Pharmaceuticals to use up the money. Countless expensive real yàn equipment has been purchased, many expensive consumables and raw materials have been consumed in countless real yàn, in the eyes of the manager Nicklaus, the real yàn room is like a bottomless pit to devour the spare funds of Heinz Pharmaceutical Company!

Of course, if a qiē shun lì is studied, then a qiē is worth it.

What cheap and abundant local anesthetic drugs mean is something that any surgeon who has seen it can say right now, let alone the shrewd businessmen of Heinz Pharmaceuticals. So John just made this request, and it was carried out by Nicklaus, Hoffman and others without discount!

Now, Yiqiē's dedication and hard work have finally made people see the hope of success.

And......

"It's still a good idea to come up with it so quickly."

On the carriage rushing to Heinz Pharmaceuticals, John thought silently with a happy face: "With the cooperation of Heinz Pharmaceuticals this time, Heinz Pharmaceuticals has established a good cooperative relationship with the Department of Chemistry of the University of Berlin, and has begun to collaborate on the pace of researching new drugs, which is what I really want to see......

……

I'll definitely code another chapter tonight.,But I don't know if I can release it.,Hire someone to fix the network tomorrow morning.。 (To be continued......)