After being reminded by Ma Yilong, the three of them remembered today's business.

Erli hurriedly led him and Zhao Hao to the biological laboratory opposite the door of the germ laboratory.

As soon as Ma Yilong entered, he saw that there were six sealed boxes on the ground, and on the pieces of paper pasted on them, the names of six counties such as 'Tongxiang' and 'Wukang' were written.

"This is the diseased silkworm sent by the six counties that were affected by the disaster, and the silkworm dustpan where it is located." Zhao Hao introduced to Ma Yilong: "I asked them to send them directly to the medical school for pathogen identification. ”

The room is full of specimens of silkworm babies, which is simply a large-scale scene of killing silkworm babies.

"......" Ma Yilong couldn't help but feel a little surprised, shouldn't this kind of thing be sent to the Agricultural College? Could it be that these guys who treat people know how to raise silkworms better than the old man?

I'm afraid they've never seen silkworms before. It's not right, medically it is said that silkworms, silkworms, and silkworm sand can all be used in medicine...... Even the white-zombie silkworm with leuveria can treat a variety of diseases.

But that's all they know about silkworms, right? Zhao Xiaozi asked them for help, didn't he ask Yu Blind?

Seeing that Ma Yilong was silent, Zhao Hao knew that he didn't believe that the medical school could also treat silkworms. He smiled at the two Li Divine Doctors: "Come, tell us what you have found." ”

"Fei Yan is in charge of this." Li Shizhen glanced at the eldest disciple and said, "It's better for you to talk about it." ”

"Yes, Master." Pang Xian Pang Feiyan responded, and then said to Zhao Hao: "After receiving the sick silkworm, we followed the 'four-step disease law' taught by Gongzi, and first compared the sick silkworm and the healthy silkworm under the microscope. It was found that the diseased silkworms suffering from taveria in three counties including Tongxiang had short oval hyphae in their blood, but there were no healthy silkworms in their blood. ”

"Silkworm disease in Wukang and other three counties is another manifestation - microscopic examination of blood can see that there are tiny particles moving, the more particles the more serious the disease, because its body color is dull and rust-colored, we tentatively call it 'rust disease'."

"Oh......" As soon as Ma Yilong heard something, he put his unhappiness behind him, and asked curiously: "What kind of microscope do you have, can you see things in blood?" ”

"Of course." Pang Xian smiled and put a piece of prepared glass under the microscope, and taught Ma Yilong to watch it after focusing on it.

"Oh my God......" Ma Yilong exclaimed unsurprisingly when he saw that there were so many things in his blood.

Pang Xian made a comparison for him one by one, and Ma Yilong stared at it carefully, as if there were indeed some differences. But he was already dizzy and couldn't see clearly.

"This means that silkworm disease is caused by these two little things?"

"At this time, it can't be said that way, you must strictly follow the 'four-step syndrome law' and get a solid proof to confirm it."

"What's the remaining three steps?" Ma Yilong's attitude immediately turned around, and he was modest like a primary school student.

"The second step is to isolate the microorganisms and obtain a pure culture in the culture medium." Pang Xian said: "The third step is to cultivate."

The raised microorganisms are inoculated back into the healthy silkworms, and the same disease will recur. The fourth step is to test the diseased silkworm carcass

If this microorganism can be disposed of, it can be proved that it is the causative agent of the disease. ”

"Well......" Ma Yilong pondered for a moment, and couldn't help but applaud with admiration: "The idea of strict prohibition is impeccable!" ”

"I'm ashamed, this microscope and the four-step disease law were all created by Zhao Gongzi, and I just sit back and enjoy it." Pang Xian said modestly.

"Hey, Director Pang can't say that." Zhao Hao was so modest that he said in his heart: "Science is a relay race, I just stuffed the baton of my predecessors into your hands." ”

The two Li Divine Doctors both nodded secretly, even though Zhao Gongzi was full of shortcomings, his modest virtue was indisputable. In fact, they mainly complained that Zhao Hao came too little...... The feeling of no one to guide you and groping your way through the darkness is too painful.

"Science......" Ma Yilong suddenly felt that he was a little too proud in the past. I always subconsciously regard science as a miracle, and I don't really appreciate its essence, and I don't really introduce it into the agricultural college.

At least compared to medical school, it's far behind......

~~

"After identifying the two sources of infection," Pang Xian took out a thick test diary from the bookcase, and continued as he flipped forward:

"We started looking at how the two diseases were transmitted. After observation, it was found that the artiania bassiana was mainly transmitted through contact with the diseased silkworms, followed by trauma infection. After the death of the diseased silkworm, a layer of white silk will be generated on the body surface, which is very easy to fall off, and the weight is light and heavy, and it will be scattered with the wind, and the healthy silkworm will be sick if it touches it. ”

"But fortunately, according to our observations, all the silkworms born from the eggs are healthy...... Even if the silkworm is hatched by a diseased moth laying eggs, until the adult moth, no pathogen can be found in the blood. Pang Xian said and looked at Zhao Hao and said, "So can it be speculated that this disease will not be inherited to the next generation?" ”

"If that's the case, the problem will be much easier!" Zhao Hao slapped his palm and smiled: "Right now, the spring silkworms have fallen, and the summer silkworms have not been raised." If all the silkworm eggs are fine, then as long as the silkworm houses and mulberry fields in these counties are completely sanitized, white zombie disease should be prevented. ”

"That's great. Beauveria bassiana's resistance to disinfectants is far worse than that of mold, and several methods of disinfection we currently have can easily sanitize it. Pang Xian laughed happily.

Ma Yilong was stunned when he heard this, and stammered and asked, "Can white-vealoa be cured so easily?" ”

He used the medicine he configured, with careful care, and could only cure eighty percent of the diseased silkworms, and he always had recurrent attacks, which was naturally a little unbelievable.

"If nothing else, it should be possible." Zhao Hao smiled and nodded.

"But don't rejoice too early, another 'silkworm rust' is much more troublesome." Li Yuanming is accustomed to pouring cold water.

"How?" Ma Yilong hurriedly asked.

"We found that the eggs laid by the sick moth give birth to silkworms that are born with disease!" I only heard Pang Xian's deep voice: "That is to say, the silkworms in the previous infection period will become the source of infection in the next period, so that the cycle of this disease will go on and on, and it will be difficult to cure it." Therefore, the method of dealing with white bruveria cannot eliminate silkworm rust. ”

"In other words, you need to find a healthy silkworm moth before you can get healthy eggs?" After all, Ma Yilong ordered Hanlin and served as a prefect, and quickly grasped the key.

"Not bad." Li Yuanming continued: "A research team found that the silkworms produced by sick eggs are stunted after hatching, and they die at the age of serious age, and die before the fourth instar at the longest. And they will infect the rest of the silkworms, so they must be resolutely eliminated! ”

"The easiest way is to destroy all the silkworm eggs in the affected counties and bring in silkworm seeds from other counties that are not diseased." Ma Yilong immediately thought of a countermeasure, and then said bitterly: "But in this way, the sericulture industry in these counties will not be able to recover for many years." ”

After the silkworm moth breaks out of the cocoon, it begins to copulate for half a day or even a day. However, as soon as they are separated, the male moth dies and the female immediately begins to lay eggs. Silkworm farmers use thick paper made of mulberry to undertake silkworm eggs, one can lay more than 200 eggs, the silkworm eggs are naturally glued to the paper, one by one evenly spread, naturally there is no accumulation. Silkworm growers collect silkworm egg paper and prepare it for the next year.

Silkworm eggs can only hatch after a dormant period of as short as half a year and as long as ten months, and they are very sensitive and fragile, once the temperature is hot and cold, or the humidity changes too much, a large number of hatches will be poor. Silkworm farmers take care of the silkworm eggs more carefully than they take care of pregnant women, and in the end, half of them survive and burn high incense.

And silkworm babies are just as fragile, and they don't form cocoons when they are slightly frightened. So much so that in the month of raising silkworms, Jiangnan is not allowed to visit the door, and the family is not allowed to cry and quarrel, and the whole family does not dare to breathe. But with such care, there are always two or three out of ten silkworms that cannot form cocoons. Coupled with the inevitable natural disasters of silkworm disease, it is always necessary to replenish half of the seeds.

Besides, now all counties still want to expand production, and the silkworm farmers' silkworm eggs are still insufficient for their own use, where can they buy silkworm eggs?

Therefore, you can't start from scratch unless you have to......

"Is there any way to distinguish a sick silkworm moth?" Ma Yilong asked with expectation, anyway, he couldn't see the difference with his eyes.

"This is the object of our research, and a research team has been set up for this purpose." Pang Xian replied: "After tracking, it was found that the black spots could not be detected in the silkworm eggs with a microscope. As the larvae gradually grow up, these black spots gradually appear, which are clearly visible in the pupal stage, and the black spots in the body of the diseased moth are already amazing, so we suggest that in order to screen out the silkworm eggs that are not infected with the disease, the moth should be used as the starting point for detection and control. ”

"Good!" Zhao Gongzi slapped his hands and praised: "Your level is advancing day by day, this time to deal with silkworm disease, it can be said that you use a knife to kill chickens!" ”

"......" Ma Yilong didn't taste it this time, but said happily and sincerely: "The level of your medical school is much higher than that of the Agricultural College, and the old man is ashamed of himself." ”

"Hey, Mr. Meng He, don't talk like that." Li Shizhen said with a faint smile: "Since the establishment of our Jiangnan Hospital, we have taken the prevention and control of plague as a top priority, and have been fighting schistosomiasis in Kunshan, so of course we have a little more experience." ”

As he spoke, he praised Zhao Gongzi as if his conscience had discovered: "This is all thanks to Gongzi for introducing science into medicine." ”

"Where, where." Zhao Hao smiled: "I just clicked the direction a little, it all depends on your accumulated hard work......

During the Xiaoice period, plagues were rampant, and the Black Death raged in Europe for hundreds of years. In the Ming Dynasty, the plague also became the last straw that broke the camel's back, and the plague epidemic that lasted for decades in northern China caused the population to die in large areas.

In particular, the plague in Beijing in October of the 16th year of Chongzhen's reign caused more than 200,000 deaths in Beijing. So much so that when Li Zicheng's troops approached the city, the plague-ridden city of Beijing could not even organize a decent resistance, and he was unhappy and hanged himself on the coal mountain......

Zhao Gongzi regarded the plague as an enemy more dangerous than the wild boar skin and Li Chuang, and from the very beginning, he had to train the 'Wu Liande' of the Ming Dynasty to lead the people of the Ming Dynasty to defeat the plague god!

Therefore, Zhao Gongzi said that this silkworm disease is also a good thing, at least let Jiangnan Hospital practice in advance on how to fight infectious diseases.

Although one is a silkworm and the other is a human, the principle is common.