"Dr. Edward, how am I doing?"

After Edward came, Li Hongyu asked everyone to wait outside the door, and asked quietly, according to the medical knowledge he mastered, it was not a good thing for him to burn at this time, so he could not let others know his situation in order to appease people's hearts.

"Your Excellency, although the operation went well, your wound caused an infection, and now I am trying to find a way to treat you." Hearing this, Edward did not hide anything, and said to Li Hongyu.

"What are the odds of success?" Li Hongyu suddenly smiled bitterly when he heard this, the thing he didn't want to see was still inevitable.

"Twenty percent." Edward pondered for a moment, and then solemnly gave Li Hongyu a number.

At present, there are no effective anti-inflammatory drugs, and once infected, he can usually only wait for death, relying on his own immunity to survive, so the mortality rate is very high, and the 20% chance has been exaggerated by him.

"Twenty percent!" Hearing this, the corners of Li Hongyu's mouth suddenly showed a wry smile, this is not such a simple thing as only one of the five people who can live, and his death has basically been pronounced.

"Dr. Edward, if there are good anti-inflammatory drugs, my condition will get better." After a moment of silence, Li Hongyu looked up at Edward.

"Yes."

Edward nodded when he heard this, then looked at Li Hongyu helplessly and said, "But as far as I know, none of the current drugs can achieve a good anti-inflammatory effect, unless a new drug can be found." ”

"Dr. Edward, what I'm going to do for you next is top secret, and you must not reveal it to anyone, can you promise me?" Li Hongyu knew what Edward meant, so he said to him in a deep voice.

"I swear in God's name that I will never tell anyone." Edward's face showed a suspicious look, and then solemnly raised his right hand and said to Li Hongyu.

"Dr. Edward, I now have a pharmaceutical method that I need you to achieve."

Li Hongyu smiled slightly when he saw this, and then said to Edward in a deep voice, "If this method can be realized, it will be refined to be an effective drug that can deal with infection, 'penicillin'!" ”

"Penicillin?" Edward was slightly stunned when he heard this, he knew about penicillium, but this was the first time he had heard of "penicillin".

"If nothing else, it works really well for infections." Li Hongyu bowed slightly, penicillin was a good anti-inflammatory medicine in later generations, saving countless lives, and he also remembered the preparation method of penicillin in a daze after being injured, so he asked Edward to give it a try.

Of course, due to the lack of medical conditions in later generations, Li Hongyu's penicillin extraction can only be refined by local methods, and whether he can succeed before his condition deteriorates depends on luck.

"Is there such a drug?" Edward's face was full of surprise, he had never heard of an effective anti-inflammatory drug in his years of practice, and he was from an Eastern population that was backward in natural sciences, so it seemed difficult to believe for a while.

"The manufacturing principle is very simple, but the actual production is more troublesome and requires a lot of thought." Li Hongyu knew from Edward's look that he was shocked by this, so he methodically and briefly explained the principle of making penicillin.

To make penicillin, a large amount of penicillium is collected, cultured with a nutrient solution, filtered, and stirred with rapeseed oil.

After stirring, the water is extracted, i.e. the refined culture, and in this way most of the intolerant and lipid-containing substances can be removed.

Then, the charcoal is ground into a powder and added to the refined culture broth to allow the charcoal to absorb penicillin.

The carbon, which has absorbed penicillin, is then placed in a container such as a separating column, washed with distilled and acidic water, and then rinsed with alkaline water.

Then the penicillin will be divided into a certain part, concentrated and then dissolved, which is the later separation tube column color layer separation method.

Finally, staphylococci were cultured in agar medium and tested for drug susceptibility to drugs, and the significant effect could be judged.

"Master Tongshi, you studied medicine?" After Li Hongyu finished explaining the principle, Edward looked at him with a stunned expression and asked, the method that Li Hongyu said just now was very professional, even he was ashamed of himself.

"I know a little bit about it." Li Hongyu smiled, he couldn't explain much to Edward now, so he then said, "Without further ado, I'll let Miss Li'er and Miss Youlan help you." ”

"Remember, this matter is the top secret of the Ming Dynasty, and it must not be leaked." As he spoke, Li Hongyu instructed in a deep voice.

Penicillin is a kind of high penicillin is an important antibiotic with high efficiency, low toxicity and wide clinical application, according to Li Hongyu's understanding, its successful development has greatly enhanced the ability of human beings to resist bacterial infection, led to the birth of the antibiotic family, and created a new era of antibiotic treatment of diseases.

In Li Hongyu's memory, penicillin was introduced in World War II, when it saved many Allied soldiers.

Therefore, penicillin is not only a medicine, but also an important strategic material, and Li Hongyu naturally does not want its production method to leak out.

Originally, in order to keep it secret, Li Hongyu didn't want Edward to participate in the production of penicillin, but wanted Yang Li'er and Youlan to do it.

However, considering that Yang Li'er and Youlan did not have enough medical knowledge, Li Hongyu still let Edward participate in it after careful consideration, and Edward in Bangkok can be said to be an expert in medicine, and the success rate of penicillin with his participation will be greatly improved.

"Don't worry, I will keep my oath." Edward also realized the importance of the matter, so he replied solemnly.

After Edward left, Li Hongyu called Yang Li'er, Youlan, and Yamashita Sakurako in, told them about penicillin, and asked Yang Li'er and Youlan to assist Edward in making penicillin, and Yang Li'er's Dutch level was enough to communicate with Edward.

Yang Li'er and Youlan were naturally reluctant to leave Li Hongyu and wanted to stay and take care of him, but when they learned that penicillin was the drug that saved Li Hongyu's life, the two of them changed their minds and decided to fully cooperate with Edward to prepare the medicine and leave Li Hongyu to be taken care of by Sakurako Yamashita.

"Li'er, if my illness worsens and I can't handle affairs, you must remind Lord Wang and General Bai not to act recklessly, I think the shooting incident is not simple, and the Spaniards should have been framed."

After explaining the penicillin matter, Li Hongyu Yufeng turned around and talked about the case, and said to Yang Li'er in a deep voice, "If they have irrational and radical actions, you will use my seal to suppress the matter." ”

"If we can't find out the truth of the case and let Gonzalez go, Daming now needs friends who can trade, not enemies."

Saying that, Li Hongyu told Yang Li'er that he didn't want the relationship between Daming and Spain to deteriorate because of his death, and he had to plan for what happened after him, and he wanted to leave a stable situation for Yang Li'er and Youlan and others.

"Let him go?" Yang Li'er's eyes showed a look of surprise when she heard this, you must know that Gonzalez is now a major suspect.

"He's a man of chivalry, and he wouldn't do anything like that." Li Hongyu bowed slightly, and opened his mouth to explain to Yang Li'er, "Just like our Ming scholars regard fame as life, Gonzalez would rather die than desecrate the chivalry he respects. ”

"But in this case, how can you explain to the imperial court?"

Yang Li'er naturally understood the chivalry of the West, knew that what Li Hongyu said was right, she knew that Li Hongyu was explaining the aftermath, so she looked at Li Hongyu with red eyes and asked, The dignified Ming auxiliary minister was shot dead in the vassal country, where does the face of the Ming Dynasty exist?

"Find a substitute for the dead ghost to carry this black cauldron and appease his family." Li Hongyu smiled bitterly when he heard this, and then said helplessly, no matter what, someone must be found to be responsible.

"You'll be fine, sir!" Hearing this, Youlan couldn't control the sadness in her heart anymore, and her tears made you burst out of her eyes, and at this time, Li Hongyu was still thinking about them and Da Ming, which made her feel quite uncomfortable.

"Don't cry, it's not beautiful if you cry." Li Hongyu smiled when he saw this, stretched out his hand to wipe the tears from the corners of Youlan's eyes, and felt inexplicably sad in his heart, he was also reluctant to Yang Li'er and Youlan and others.

After Yang Li'er, Youlan, and Sakurako Yamashita left, Li Hongyu asked Gonzales to bring Gonzales, presumably Gonzalez's current mood must be extremely complicated, and this kind of feeling of being wronged is not pleasant.

"Mr. Tongshi, I didn't let you shoot you." After seeing Li Hongyu lying on the hospital bed, Gonzalez's face changed a few times, and then said solemnly, he is not the kind of person who shirks responsibility, but how can he admit what he has not done?

"I believe in you." Li Hongyu smiled when he heard this, and stretched out his hand to the seat in the room, "Please take a seat." ”

"You believe me?" Gonzalez was stunned when he heard this, Li Hongyu's reaction was beyond his expectations, and he looked at Li Hongyu suspiciously after sitting down.

"I should have been born into a noble family, so I was proud, and I was raised in chivalry, which does not allow you to commit such a despicable act of assassination." Li Hongyu bowed slightly, and then opened his mouth to explain.

"Thank you for believing in me." Gonzalez's face softened when he heard this, and he secretly breathed a sigh of relief, since all the evidence was now against him, he was really at a loss for words.

"What enemies do you have?" Li Hongyu coughed a few times, and then asked in a deep voice, the reason why the other party framed Gonzalez, then of course he had to use Gonzalez as a starting point to investigate.

"I've just been in Bangkok for a short time, so I don't have this kind of enemy who wants to kill me." Gonzalez thought for a moment, then shook his head at Li Hongyu.

"If it's not your enemy, then the opponent's target is Spain behind you." Li Hongyu pondered for a moment when he heard this, and then said with a serious expression, "Which country do you have the worst relations with in Bangkok?" ”

"Holland!" Gonzalez's eyes lit up, and Li Hongyu's words invisibly reminded him, and he looked at Li Hongyu with some surprise and asked, "Could it be that the Dutch did it?" ”

"It's just a possibility, it's not certain."

Li Hongyu shook his head, and then explained to Gonzalez, "Since the interests of overseas markets are involved, any country from the West may be the mastermind of this matter, and no one wants to see your Spanish power overseas getting stronger and stronger." ”

At the beginning of the 17th century, despite the loss of the Armada in the battle with the English navy, the Spanish navy remained the most powerful maritime power in Europe.

Therefore, European countries certainly do not want to see Spain continue to expand its influence abroad, they are competitors to each other, so they may all be guilty of Spain.

Therefore, in addition to the Netherlands, which is now at war with Spain, Britain, which had fought a large-scale naval war with Spain, is also seriously suspected, and countries such as France and Germany are also inevitably involved.

Gonzalez knew what Li Hongyu meant, and his brows suddenly furrowed, and after Li Hongyu reminded him of this, he realized that the situation was much more complicated than he thought.

"Isn't there a way to determine which country did it?"

After a long time, Gonzalez looked up at Li Hongyu, the murder of Li Hongyu was not only related to his reputation, but also involved Spain's interests in the East, and he was definitely unwilling to bear this black cauldron.

"No crime in the world can be perfect, and it will definitely leave clues." Li Hongyu groaned slightly when he heard this, and then said to Gonzalez with a serious expression, "The first clue they left is the gunman's information. ”

"Gunman's information?" Gonzalez looked at Li Hongyu with some confusion, as if there were no other clues except for the musket and the fabric of the Spanish army's uniform.

"It was a complicated environment, and the gunman was quite far away from me, but he was still able to hit me accurately, which shows that he is a master with a musket."

Li Hongyu nodded and explained to Gonzalez in an orderly manner, "In addition, he was able to escape under the pursuit of many pursuers, which shows that he is very familiar with the surrounding environment, and due to the suddenness of yesterday's duel, it is impossible for the other party to step on the point, which means that he must have been in Bangkok for many years." ”

"The locals in Bangkok are not proficient in muskets, and the other side's muskets are definitely soldiers from European countries, and they are officers, and only officers are in a position to do a lot of shooting training."

After listening to Li Hongyu's words, Gonzalez's eyes suddenly lit up, Li Hongyu's words made his mood suddenly brighten, and he said to Li Hongyu with some excitement, "Just check which country has been in Bangkok for a long time and the officers who have a good musket can lock the murderer's target!" ”

"As for the situation of the military camps of other countries in Bangkok, I think the people in your military camps know very well, if you think about who is most familiar with the situation of the military camps of various countries in Bangkok, I will let him come to meet you."

Li Hongyu smiled slightly when he heard this, he seemed to have no clue about being shot, but in fact, as long as he peeled off the cocoon, he could analyze a lot of information from it, and then look for flaws according to this information.

"Captain Rohr."

Gonzalez said a name without hesitation, "Captain Rohr has been in Bangkok for five years and knows the situation in the military camps of various countries very well. ”

"Okay, I'll have Captain Rohr fetched." Li Hongyu secretly breathed a sigh of relief when he heard this, hoping that this Captain Luo Er could provide useful information and then find out the gunman.

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