Because the Uesugi family urgently needed to seize the territory of about 300,000 koku in the seven counties of Kasai (Tsazawa-gun, Esashi-gun, Iwai-gun, Iwasen-gun, Moto-sen-gun, Benyoshi-gun, Tome-gun, and Momo-gu gun) to carry out land seizures and castle destruction, the court had no choice but to acquiesce to Anton Aiji's attack on the Asari family. However, the court intensified its invasion of Yuri-gun.

Three years of Yonglu, January 1. On the occasion of the New Year, the court ordered the lord of Yomejo Castle, who remained in the three counties of Shonai, to assemble their troops and march north to cooperate with Katsunaga Shirobe and others to invade Yuri Gun.

Beginning in September of the second year of Eiroku, Katsunaga Sekabe led by Shitomi Tsukiji, Yorisada Tendo, Mitsunobu Nobuzawa, Keitsuna Takemata, Tadahide Okawa, Keiko Chisaka, and Keigaga Yamamoto Temple will succeed Shigee Shinbata, Mitsukin Suda, Tadanao Shimazu, Tadanao Fujita and other generals in the Shonai invasion of Yuri County The progress of the invasion of Yuri County is still relatively fast. In addition to the owner of the Nejokan, Oi Mitsuyasu (Yajima Mitsuyasu, Onodera Keimichi's son-in-law Onodera Shigeromechi), the forces of the Takizawa family, the Corn family, the Ishizawa family, the Shimomura family, the Ziyoshi family, and the Hanekawa family were successively destroyed by the Uesugi army. However, the owner of the Serita Pavilion, Serita Jushi, was unable to defend himself, so Katsucho Sebe temporarily gave up this place and went north to attack the wealthy families such as the Lagoon family and the Ziyoshi family. Serita Ryo borders the three counties of Shonai, and it happens to be the first battle in which the security of Nokata, the Yoshiji left behind, Kanetomi Itagaki, and Mamoru Itagaki Kawachi will enter Yuri-gun.

General Bao Nokata, Ryori Yoshi, Itagaki Kanetomi, Itagaki Kawachi Mamoru and other generals led more than 800 people to march at night and attack the Serita Pavilion where Serita Jumi was located. Serita Jumi closed the city gate, and the remaining Yoshishi ordered several of his men to climb the wall and enter, and then open the Otemon Gate. Since Serita Jumi was a small wealthy family, the structure of the warp wheel of the city wall was very shabby, so Imai Hyogo, a retainer under the command of the Yoshishi clan, led several ashigaru to climb the wall and enter the castle, but he also succeeded in opening the castle gate. However, several castle soldiers on Seratora's side noticed the movement and picked up their guns and stabbed them, although Imai Hyogo and several Ashigaru were stabbed by the castle soldiers, and even fled in embarrassment. However, fortunately, the castle gate had been opened, and the generals such as Baoan Nokata, Stay-behind Yoshiji, Itagaki Kanetomi, and Itagaki Kawachi Mamoru led their troops to quickly attack the Serita Pavilion, and it didn't take long to capture this very shabby small castle, and set fire to it, and also beheaded Serita, who was against the Uesugi family.

After that, the generals such as the security Nokata, the Yoshiji who stayed behind, Kanetomi Itagaki, and Mamoru Itagaki Kawachi attacked the Ayukawa family and the Ishizawa family again. As a result of the last experience, the security Nokata, the left-behind Yoshi, Itagaki Kanefu, Itagaki Kawachi Mamoru and so on will be more unscrupulous and more open. The castles of the Ayukawa family and the Niga Ho family are also the same as Seratorikan, very simple and short. The generals such as the security nohshi, the left-behind Yoshi, Itagaki Kanefu, and Itagaki Kawachi Mamoru simply ordered all the troops under their command to climb the wall and enter the city in one go. Imai Hyogo, the retainer who stayed behind in the Yoshiclan, and the Tajiri Pavilion owner, Security Yojiro, and others entered the city first, and their performance was the most prominent, but they were also stabbed by the defenders of the castle with guns and suffered a certain degree of injury. In the end, the generals such as Baoan Noshi, Staying in Yoshiji, Itagaki Kanefu, and Itagaki Kawachi Mamoru still successfully captured Higa's Castle and Nishime Castle, and killed more than 500 people from the Niga's family and the Ayukawa family. At this point, under the hard work of the Minamiide Uesugi retainers, the Uesugi army captured most of Yuri-gun, and many Yuri-gun wealthy clans who colluded with the Yasuto family, Hiyama Yasudo family, and Tozawa family were leveled.

On January 5th, Anan Nokata, Yoshiji Liumori, Kanetomi Itagaki and Mamoru Itagaki Kawachi will join Katsunaga Shibabe, Shitoyo Tsukiji, Yorisada Tendo, Notsunobu Takesawa, Keisuna Takemata, Tadahide Okawa, Keiko Chisaka, and Keinaga Yamamoto Temple will merge at Kosukegawakan, and at this time, only the Akao Tsu family, the Otsushi family, and the Iwaya family will be left among the Yuri Twelve.

Since the territory of the three wealthy families of the Akao Tsu family, the Tatsu family, and the Iwaya family is exactly in a triangle shape, they can be horns and rescue each other. Hiraoka Castle, Iwaya Castle, and Akaotsu Castle, where the Akaotsu family, the Taetsu family, and the Iwaya family depended, were all mountain castles that were easy to defend and difficult to attack, and a long-term confrontation would be extremely disadvantageous to the besieging side. At that time, Akao Tsu Ieho himself was personally in charge of Akao Tsu Castle, so Sebe Katsunaga took the opportunity to attack Takayama Castle and Matsunosaki Castle behind Akao Tsu, and captured Matsunosaki Castle, Takayama Castle, Ashikawa Castle and other branch cities around Akao Tsu Castle, and slaughtered more than 500 defenders in Matsunosaki Castle, Takayama Castle, Ashikawa Castle and other places, which made the gate of Akatsu Castle wide open and there was no danger to defend.

At the same time, Tiantong Lai Zhen and Yan Ze Manyan led their elite soldiers and began to attack the Yue family and the Iwaya family. Tiantong Yorizhen and Yanze Manyan ordered the troops under their command to bite a wooden stick in their mouths, and the horses they rode tied their tongues, so that they did not make a sound during the march, and unknowingly marched to Hiraoka Castle, where Mitsushige was located, and Iwaya Asamomori, where Iwaya Asamomori was located, and Mitsushige and Iwaya Asamomori did not expect that the Uesugi army would attack overnight. After defeating Koshiko Mitsushige and Iwaya Asasei, Tendo Yorisada and Nobusawa Mannobu divided their troops to garrison Hiraoka Castle and Iwaya Castle to prevent the Akao Tsu family from attacking.

When Mitsushige and Iwaya Asamoto led the remnants to flee to Mt. Sasamori, they were raided by the Yamamoto Temple Keichobu, who had been in ambush for a long time, and the two of them, Mitsushige Okotsu and Iwaya Asamoto, who were suddenly attacked, were caught off guard and were soon killed by the Uesugi army.

In the early morning of January 6, Akao Tsuieho was horrified when he learned that Matsunosaki Castle, Takayama Castle, Ashikawa Castle, Hiraoka Castle, Iwaya Castle and other places had been captured by the Uesugi army, so he had to strengthen the garrison of Akaozu Castle.

However, Katsucho Sebe did not intend to give Akao Tsu Iebo time to strengthen the castle defense of Akao Tsu Castle, and quickly ordered Takemata Keitsuna, Okawa Tadahide, Tsukiji Shitoyo, Itagaki Kanetomi, Itagaki Kawachi Mamoru and other generals to lead an army of 5,000 to launch a fierce attack on Akao Tsu Castle, and organized hundreds of iron artillery ashigaru to fire at Akao Tsu Castle.

Because the Akao Tsu army had not yet learned the benefits of iron cannons before. As a result, under the iron artillery attack of the Uesugi army, the Akaotsu soldiers and horses were frightened and in chaos. Soon, the Uesugi army took advantage of the situation to defeat Ninomaru and Nishinomaru of Akao Tsu Castle. After seeing that he could no longer hold Akao Tsu Castle, the Akao Tsu family committed suicide with his eldest son Akao Tsu Mitsumasa, his second son Akao Tsu Michitoshi and others in Honmaru.

With the fall of Akao Tsu Castle and the demise of the Akao Tsu family, Yuri Twelvehead disappeared from the stage of the two countries in Tohoku Ou.

Since the governor of the Minato family was replaced by Anton Moji, the younger brother of Anton Aiji, at this time, he was unable to provide assistance to Yuri's twelve heads. However, the Minato and Hiyama Anto clans were thus unified, and Anton Aiki basically swept away the interference of the weak forces around him, and there were no worries, and his territory was completely connected with the Nanbu clan, and it was only a matter of time before he invaded Mutsu. It's completely free to attack the southern territory.

Knowing the news that Harimasa Nanbu personally led 4,000 troops south to Ichigo Castle, Anton Aiji, seeing that the time was ripe, began the long-prepared Hokji-aku invasion campaign, and its primary target was naturally the relatively wealthy Antler Prefecture.

Long before the Antlers invasion, in the second year of Yongroku, Anton Aiji had already begun to work on diplomacy. The Antlers County is easy to defend and difficult to attack, and all the surrounding forces are well aware of this, so in order to maximize the benefits of their military actions, it is often the best strategy to coerce and induce the enemy internally. Of course, judging from the actual situation of the Hiyama Andong family at that time, the war with the Asari family had just ended, and the consumption of the Hiyama Andong family was still relatively large, so it was naturally not appropriate to send troops to Antler County at this time.

Anton Aiji first sent his retainers to defend the twelve castles, which were important transportation points in Antler County, to put pressure on the local lords, and then sent his retainers to lobby. This trick really worked, and successively the national lords of the Antler County, such as the Osato family, the Hanawa family, and the Chai Uchi family, fell to the side of the Hiyama Ando family, and then the national lord of the Nishitsugaru region, Kasei Ziqing, took the initiative to fall to the Hiyama Andong family because he was dissatisfied with the rule of the southern family. After some recuperation, Anton Aiji is finally ready to launch his invasion of Antlers.