Chapter 58, Drug Experiments

In the real yàn room, Shi Gaozhi hastily used dozens of rabbits to verify the efficacy of the sulfonamide he made, and found that it is indeed very effective in killing bacteria, and after the medicine, those rabbits are still alive, one is dead or nothing, only two are too alive, and they always like to rub their bodies on the wall of the cage.

"Boss, do you think there is something wrong with these two rabbits?" Hanks, a member of the real yàn, was much more concerned about the safety of the drug than Scrooge, so he quickly reminded Scrooge who was about to fill in the side effects column on the research report with "no obvious toxic side effects".

"Oh, don't you see they're alive?" Scrooge said disapprovingly.

Scrooge certainly knew what was going on, and that was the typical reaction of a sulfonamide allergy. Like other antibiotics, sulfonamides can cause allergic reactions. And compared to things like penicillin, sulfonamide allergies are more difficult to detect in advance. Fortunately, the allergic reaction of sulfonamides is much gentler than that of penicillin and the like, and it is nothing more than some skin reactions and lung reactions. Well, that is, there are some drug rashes, and then a little asthma or something, although it can also lead to shock when it is strict, but the probability is very low. Generally speaking, sulfonamide allergy does not kill people.

But Hanks, a recent immigrant who, according to his own account, studied chemistry at the University of Hamburg. However, he did not have a graduation certificate, because he violated the operating procedures of the real yàn room and was found out in private, and was expelled as a result.

Scrooge didn't know if what Hanks said was true or false, but he asked Hanks a few questions, and asked him to do a real thing, and found that Hanks was indeed trained in this area, so he retained the guy. Of course, Scrooge wouldn't give him the salary of a college student.

Hanks grabbed the two rabbits out of their cages and took a closer look.

"Boss, both rabbits have some herpes on their skin, and there are a lot of them on their lips and anus."

This is a typical symptom of a sulfonamide allergy. Scrooge nodded and said, "Stop medicating these two rabbits, give them plenty of water, and then see how it goes." Well, Hanks, I'll leave that to you. ”

A week later, Hanks came running and reported, "Boss, those two rabbits are fine." ”

"Oh, I see. What about other rabbits? Scrooge asked without raising his head.

"It's all good." Hanks replied.

"Well, then drag all those rabbits back to the market and sell them, and recoup the cost. In addition, prepare to prepare, tomorrow we will go to the hospital together for clinical practice. ”

"So fast! The creature has just been completed...... "In fact, Hanks thinks that the sloppy creature yàn is not completely finished.

"Because there are a few sepsis patients who are dying, and if they don't go, they will have to go to God." Scrooge said, "Anyway, they have no cure, just waiting to die, even if there is a problem with our medicine, for them, can it still be bad?" ”

……

Hospitals in the 19th century were still haunted places, not only because in the era when antibiotics were not discovered, but doctors did not have any special treatment for many diseases. At that time, people didn't even know the relationship between bacteria and diseases, and of course they couldn't talk about disinfection and sterilization. A scalpel, after dissecting the body of a patient who had died of tetanus, might be wiped with a towel and used to operate on another patient who was temporarily alive (in fact, dead), and a sheet just placed under the body of a patient who had died of cholera might not have been washed and laid on another patient's bed. As a result, when patients arrive at the hospital, not only can they not receive effective treatment, but they will also infect each other, and as a result, it has become the norm for patients to enter the hospital vertically and carry them out horizontally. In obstetrics and gynecology, for example, for most of the nineteenth century, the mortality rate of pregnant women giving birth in hospitals was more than 10 to 100 times higher than that of giving birth at home. After giving birth, death due to bacterial infection is even a fight with cholera smallpox. Patients and their families know this, too. So the patients who are sent to the hospital are either sick and dying, or because the disease is contagious. In fact, many people were sent to the hospital before their families organized a funeral for her. If there is any advantage of 19th-century hospitals, the only advantage is probably that there are no doctors. Because it is already a social consensus that going to the hospital is equivalent to death.

A few days ago, Scrooge's men came to the Baptist Charity Hospital, called Salvation, and explained to the director that they had a new drug that had a miraculous effect on sepsis, and that it had achieved good results in animal practice, and that they hoped to find a few patients with sepsis in this hospital to test the efficacy.

If this kind of thing is placed in the 21st century, it is definitely a very troublesome thing. The director of the hospital would not agree to such a businessman without any qualifications to come to the hospital to test any new drugs. However, fortunately, at this time it was still the 19th century, and there was no strict qualification management system at all, and as long as the patient or the patient's family signed for drug testing, no one cared about it. Not to mention that this is also a lovely charity hospital. The so-called charity hospitals are generally "free" hospitals run by churches or other groups. Patients who come to such hospitals for treatment generally have two characteristics: first, they have no money; Second, it's basically hopeless. Convincing such patients to sign a voluntary trial of a new drug that could save their lives is a simple task.

As a free charity hospital, the scale of the "Salvation" Hospital is very small, and its entire campus is an abandoned warehouse, where outpatient clinics, wards, operating rooms and so on are all in that large warehouse. Because the hospital is converted from a warehouse, the lighting conditions are very poor. So much so that when Scrooge and a few assistants, under the protection of several Blackwater security guards (no way, the hospital is in a slum, and the security here has always been very chaotic), came in through the gate of the hospital, their eyes did not adjust for a long time.

It took a while for Scrooge to get a good grasp of what was going on inside the hospital: several beds were laid out in dark corners, and the yellowed sheets were stained with old black blood. The ground was piled with all sorts of dirty stuff, and swarms of green-headed flies were buzzing there. The operating room is simply separated by a curtain of cloth.

"Hello, Mr. Scrooge, I am Heathfeld, the director of the hospital." A little old man held out his hand to Scrooge, well, it didn't seem to have scrubbed blood or something else.

Scrooge glanced at the guy and didn't stretch out his hand, but instead stuck his hand into his pocket of hundreds of millions.

"What are you kidding, when I don't know what kind of virtue a nineteenth-century hospital was? This is definitely a petri dish for all kinds of pathogenic bacteria! Look at that hand again, God knows what's on it? I was stupid to shake your hand! Scrooge thought.

Seeing Scrooge's actions, the dean was not too embarrassed, because he also realized that his hands were a little too dirty. So he wiped his hand on his apron casually, and said to Scrooge: "I'm sorry, I just finished delivering a girl, and I haven't had time to ...... yet."

Because Scrooge had promised to donate a little to the hospital, the director was very courteous, and he told Scrooge that there were now four patients in the hospital who had symptoms of sepsis for various reasons, and that they were willing to be treated after learning that there was a drug that might save their lives.

"Okay, then let them sign the power of attorney." Scrooge said he didn't want to stay in this place for a minute. The air in this place is full of all kinds of germs, and it is too dangerous.

The dean led a few people to the bedside, and Scrooge's entourage took out the authorization agreement from his purse, which would be a typical illegal agreement if it were placed in the future. Because it deprives the patient of almost any rights, according to it, no matter what problems arise with the patient thereafter, Scrooge and them do not have to bear any responsibility. When the lawyer Mr. Scrooge hired to draw up the agreement for Mr. Scrooge, Mr. Scrooge was worried about whether it was legal. But the lawyer told him that all such agreements were like this. This thing is definitely legitimate. So Scrooge sighed heartily: "This is really a golden age of rich people!" ”

Naturally, the patients who were about to be called away by the Lord would have no objection to this agreement. In fact, at this time, you just stretch out your long paws, take out an agreement written on parchment with a mysterious flame, and tell them that if you sign it, you will not die, well, many patients will sign it too.

Seeing the patient's signature, Scrooge motioned for Hanks to take out the medicine and give it to the dean, and explained to him the dosage and precautions for the medication. Scrooge noticed the sparkle in the patients' eyes when they saw the glass bottle containing the potion, which made him a little uncomfortable. "When did I get bored sympathy for these NPCs?" Scrooge thought.

……

Coming out of the hospital, Scrooge got into the carriage without saying a word, and Hanks sat next to him.

"Hanks, just came out of the hospital, what do you think?" Scrooge said.

"It's horrible! And those who are not sick will die of sickness there. If one day I get sick, I'd rather shoot myself in the head than sleep in a filthy place like that. ”

"It's not like that in rich people's hospitals, Hanks. In this world, heaven and hell are real, if you have money, you live in heaven, and if you don't have money, you fall into hell. Let's make money! Scrooge said.

"Boss, you're right, I must work hard, earn more money, and live a good life." Hanks thought Scrooge was encouraging him, so he replied. He didn't know that Scrooge was saying more to himself.

……

Perhaps it was because the germs of this era were still very pure, and they had not yet been poisoned by various chemical and biological weapons called antibiotics, so they did not have time to develop drug resistance and other things. Therefore, the effect of these drugs is amazing, and according to the news from the "Salvation" hospital, after only a week of treatment, the four patients have gradually recovered. It seems that it is already possible to expand the scope of the trial. And the time should not be far off for this drug to finally be put on the market.