Chapter 5 Toxic Bacteriophages
From the moment he recovers his mind, Hogu is at a disadvantage because the single-cell cluster does not have 'vision' and is very passive.
It was only when the foreign cells came into contact with the cluster of single cells that Hogu was able to learn of each other's presence.
Even if you don't have vision, you can sense the direction of fluid flow through the neural network of your skin and judge the objects around you.
The problem is that the single-cell cluster that Hogu is currently hosting is so rudimentary that this kind of thing is just as difficult to do.
To defend against those external threats, Hogu had to retreat to passive defense, and the key to this passive defense lies in the cell wall.
"The main attack mode of the bacteriophage is infection, and then the dove occupies the magpie's nest, and in the parasitic cell, it copies its own offspring in large numbers, and after reaching a certain number, destroys the cell membrane and cell wall from the inside out in various ways......"
"So...... The key to defending against this kind of enemy is that in the initial infection stage, as long as this link is destroyed, those guys will not be able to take me for the time being. ”
So, a question was put in front of Hogu - by what means should it destroy the infection stage of the phage?
The key to defending against bacteriophages is the cell wall, but this is only Huo Gu's idea, and the specific details have not yet been figured out.
"The original mild bacteriophage was an injection that bypassed the cell membrane responsible for defense and implanted its own genes into a single cell......
"If the cell wall is thick enough and the gap is small enough to allow only small molecules to enter and exit, well, then it can be very defensive."
With a general direction, it was much faster in terms of supplementing details, and Huogu didn't spend much energy to finalize the travel of the cell wall.
Suddenly, something occurred to Hogu.
"Wait! If it is like some influenza viruses, it deliberately destroys its own protein shell, directly transports gene fragments, and bypasses the small molecule voids in the cell wall......"
"Only the specialized type can maximize the effect, and if the cell wall is used to take into account the function of screening, then the protective effect will be ......."
Hogu's attention gradually shifted to the location of the cell membrane.
"The screening function is left to the cell membrane, and the defense work is left to the cell wall."
"If the cell wall can be broken through, then the defense of the cell membrane will not play a big role, after all, the 'balanced type' is not as effective as the 'specialized type'."
For better comparison, Hogu uncoiled and copied the genes of the phage protein shells in the gene chain.
After a while, the empty shell of the bacteriophage protein appeared in front of Huogu.
"This ......"
When he saw the empty protein shell of the phage, Hogu was in trouble.
With the comparison of the real thing, it found that the phage is very small, if the single cell as a host is a high-rise building, then the phage is the body size of a person or a pet dog.
It's really not quite what it thinks.
"In other words, the opening of the cell wall should be designed to the extent that it can only pass through a single small molecule in order to act as a phage?"
Just then, another unexpected visitor met a cluster of single cells.
As Hogu feared, the killer of the microbial world is a bacteriophage, and this time, the heavens do not intend to continue to favor Hogu and this single-cell cluster.
Immediately after the gene fragment invaded the outermost single cell, the phage immediately declared its sovereignty over the parasitic cell, frantically transcribing its own genes, creating a large number of phage genes and those protein shells.
Obviously, this is a toxic bacteriophage.
"Damn it!"
Hogu almost didn't scold, parasitic on a single cell with a protein structure connection, which meant that it was impossible to separate from the entire cluster of cells at once as he did last time.
Not daring to hesitate too much, Hogu immediately commanded the cells to divide and isolate the infected single cells.
It is not a single cell that is directly connected to the parasitic cell, but a cell that is centered on the parasitic cell and the entire area at the edge.
This is done just in case, the speed at which individuals in a cluster of single cells are separated is the speed at which a single cell replicates, and if the rate at which a single cell replicates itself cannot keep up with the speed at which the phages break down the parasitic cells, then it is pointless to let the docking cells divide and isolate.
As a result of failed isolation, large areas, or even entire clusters of single cells, will be infected.
Hogu couldn't afford to take that risk.
The development, as Hogu feared, was even worse, as the toxic phages had broken open the membranes of the parasitic cells and infected other cells faster than expected.
At this time, the unwinding division of a single cell is only halfway through.
One of Hogu's hearts hung in the air, focused on the cells that were dividing.
In the past, those single cells that seemed to him to divide at a reasonable rate now seem to be slow to a turtle speed.
"Hurry up... Hurry up... Hurry up ......"
His attention shifted back and forth between the cells and the phage, and Hogu was unconsciously chanting the single cells that were dividing.
The minutes just passed.
I don't know if this kind of fragmented urging really had a certain degree of effect, or if it was just a coincidence, the single cell that was dividing, the single cell took the lead in completing the division, separating and abandoning the entire single cell area in the vast darkness to avoid the second large-scale infection of toxic phages.
"We can't let this happen again, and we have to get the cell wall tuned as soon as possible."
Huogu, who has experienced this toxic phage crisis, has palpitations and is more eager to complete the cell wall that can resist phages.
After replenishing the missing parts of the single-cell cluster, Hogu began to work on the cell wall.
The thickness of the cell wall is not an issue, and if the cell wall is repeated several times, a superposition effect can be created to increase the thickness of the cell wall.
The problem that plagues Hogu now is the permeability of the cell wall, which is accidentally obtained, the tunnel that interacts with matter, and can accommodate several phages in and out.
Obviously, the tunnel was too big, and the accidentally obtained cell wall did not provide any defense against the phages.
If it's a single one, it's fine, as long as you don't enter the tunnel, you can resist it, but if it's facing a cluster of phages, then the situation where phages enter this tunnel is almost inevitable.
"We have to find a way to reduce this tunnel."